Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in intestine and neurons. Is an ortholog of human EHF (ETS homologous factor); ELF3 (E74 like ETS transcription factor 3); and ELF5 (E74 like ETS transcription factor 5).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is an ortholog of human ETV1 (ETS variant transcription factor 1); ETV4 (ETS variant transcription factor 4); and ETV5 (ETS variant transcription factor 5).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Involved in gonad development and regulation of cell division. Predicted to be located in nucleus. Expressed in head neurons and pharynx. Is an ortholog of human ELF1 (E74 like ETS transcription factor 1); ELF2 (E74 like ETS transcription factor 2); and ELF4 (E74 like ETS transcription factor 4).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in diabetes mellitus (multiple); hematologic cancer (multiple); and thrombocytopenia. Is an ortholog of several human genes including ETS1 (ETS proto-oncogene 1, transcription factor); ETS2 (ETS proto-oncogene 2, transcription factor); and ETV6 (ETS variant transcription factor 6).
Is affected by cyc-1; ets-4; and eat-2 based on microarray studies. Is affected by methylmercuric chloride and multi-walled carbon nanotube based on microarray and RNA-seq studies.
Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Part of RNA polymerase II transcription repressor complex. Expressed in vulval precursor cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Lewy body dementia; and schizophrenia. Is an ortholog of human ELK1 (ETS transcription factor ELK1).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in nervous system. Is an ortholog of human FEV (FEV transcription factor, ETS family member).
Predicted to enable U3 snoRNA binding activity. Predicted to be involved in endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of 90S preribosome. Expressed in tail. Is an ortholog of human TBL3 (transducin beta like 3).
Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of axon extension involved in regeneration and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including P1; germ line; head; socket cell; and sperm. Human ortholog(s) of this gene implicated in ovarian cancer. Is an ortholog of human SPDEF (SAM pointed domain containing ETS transcription factor).