- pha-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; pharynx development; and positive regulation of metabolic process. Located in nucleus. Expressed in several structures, including arcade cell; enteric muscle; gonad; pharynx; and rectum. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); lung carcinoma (multiple); and type 2 diabetes mellitus. Is an ortholog of human FOXA1 (forkhead box A1) and FOXA2 (forkhead box A2).
- fkh-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in head neurons.
- fkh-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus.
- fkh-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Located in nucleus.
- fkh-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity. Involved in several processes, including nematode larval development; neuron differentiation; and non-motile cilium assembly. Located in nucleus. Expressed in several structures, including AWB; Daaa; body wall muscle cell from D lineage; head muscle; and somatic nervous system. Is an ortholog of human FOXG1 (forkhead box G1).
- fkh-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in gonad and pharyngeal neurons. Is an ortholog of human FOXL3 (forkhead box L3) and FOXL3-OT1.
- fkh-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including intestine; neurons; pharynx; reproductive system; and ventral nerve cord. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); communication disorder (multiple); and tuberculosis (multiple). Is an ortholog of human FOXP2 (forkhead box P2).
- fkh-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables sequence-specific DNA binding activity. Involved in male germ-line sex determination and male gonad development. Predicted to be located in nucleus. Expressed in gonadal sheath cell; male gonad; somatic gonad precursor; spermatheca; and in male. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 4. Is an ortholog of human FOXI2 (forkhead box I2) and FOXI3 (forkhead box I3).
- fkh-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anatomical structure morphogenesis; cell differentiation; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ASEL; ASER; head neurons; neurons; and tail neurons. Human ortholog(s) of this gene implicated in several diseases, including lymphedema-distichiasis syndrome; obesity; and type 2 diabetes mellitus. Is an ortholog of human FOXC2 (forkhead box C2); FOXL3 (forkhead box L3); and FOXL3-OT1.
- fkh-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including axon regeneration; determination of adult lifespan; and learning or memory. Acts upstream of or within ERAD pathway and defense response to other organism. Located in nucleus. Expressed in several structures, including intestine; neurons; pharyngeal-intestinal valve; rectal valve cell; and somatic nervous system.