Enables DNA-binding transcription factor activity. Involved in several processes, including cellular response to zinc ion; fatty acid metabolic process; and positive regulation of macromolecule biosynthetic process. Located in nucleus. Expressed in several structures, including amphid neurons; head; intestine; and neurons. Used to study alcohol use disorder. Human ortholog(s) of this gene implicated in several diseases, including carotid artery disease; diabetes mellitus (multiple); and vascular dementia. Is an ortholog of human SREBF2 (sterol regulatory element binding transcription factor 2).
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ABpla; ABplp; ABpra; and ABprp.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in anterior/posterior pattern specification; regulation of neurogenesis; and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including ABpla; ABplp; ABprp; MSaa; and MSpa.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including amphid sheath cell; coelomocyte; ganglia; non-striated muscle; and rectal gland cell.
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in several structures, including E; Ea; Ep; MSa; and MSp.