pkc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein kinase C activity. Involved in several processes, including nervous system process; regulation of presynaptic dense core granule exocytosis; and signaling. Located in cholinergic synapse and neuron projection. Expressed in ganglia; linker cell; and neurons. Human ortholog(s) of this gene implicated in cerebral infarction. Is an ortholog of human PRKCE (protein kinase C epsilon).
kin-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein kinase regulator activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body; nucleus; and plasma membrane bounded cell projection. Part of protein kinase CK2 complex. Expressed in germ cell; gonad; intestine; pharynx; and vulva. Human ortholog(s) of this gene implicated in leiomyoma. Is an ortholog of human CSNK2B (casein kinase 2 beta).
kin-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including
daf-16;
daf-12; and
sir-2.1 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.
kin-32 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP binding activity and protein tyrosine kinase activity. Predicted to be involved in regulation of cellular component organization and signal complex assembly. Predicted to be located in dendritic spine and focal adhesion. Expressed in body wall musculature; head mesodermal cell; head neurons; and uterine muscle. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); ductal carcinoma in situ; and endometrial hyperplasia. Is an ortholog of human PTK2 (protein tyrosine kinase 2).
kin-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables cAMP-dependent protein kinase activity. Involved in positive regulation of oocyte maturation. Predicted to be located in cytosol and nucleus. Predicted to be part of cAMP-dependent protein kinase complex. Expressed in several structures, including excretory cell; gonad; head muscle; intestine; and ventral cord neurons. Human ortholog(s) of this gene implicated in several diseases, including adrenal cortical adenoma; platelet-type bleeding disorder 19; and primary pigmented nodular adrenocortical disease. Is an ortholog of human PRKACA (protein kinase cAMP-activated catalytic subunit alpha).
kin-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity. Involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process. Located in centrosome; cytoplasm; and nucleus. Expressed in several structures, including BDU; marginal cell; seam cell; tail; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease and inclusion body myositis. Is an ortholog of human CSNK1A1 (casein kinase 1 alpha 1).
kin-29 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables histone deacetylase inhibitor activity and protein serine/threonine kinase activity. Involved in several processes, including dauer entry; positive regulation of growth rate; and transforming growth factor beta receptor signaling pathway. Located in cytoplasm and nucleus. Expressed in body wall musculature; hypodermis; intestine; nervous system; and non-striated muscle.
kin-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in
hyp6 and
hyp7 syncytium.
kin-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in
hyp6 and
hyp7 syncytium.
kin-30 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and reproductive organ cancer (multiple). Is an ortholog of several human genes including FLT3 (fms related receptor tyrosine kinase 3); KIT (KIT proto-oncogene, receptor tyrosine kinase); and PDGFRA (platelet derived growth factor receptor alpha).
unc-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable calmodulin binding activity and syntaxin-1 binding activity. Involved in regulation of multicellular organismal process; spermatogenesis; and synaptic vesicle exocytosis. Located in presynaptic active zone. Expressed in head neurons; neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis. Is an ortholog of human UNC13C (
unc-13 homolog C).
twk-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in cholinergic neurons and ventral cord neurons.
pgp-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATPase-coupled transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Expressed in amphid neurons and intestine.
dxbp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable double-stranded DNA binding activity. Predicted to be involved in DNA damage response and DNA replication. Located in nucleolus. Expressed in several structures, including somatic cell. Is an ortholog of human KIN (Kin17 DNA and RNA binding protein).
csk-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein tyrosine kinase activity. Involved in several processes, including feeding behavior; muscle cell development; and nematode larval development. Located in cell-cell junction and plasma membrane. Expressed in several structures, including anus; head neurons; hermaphrodite somatic gonadal cell; pharyngeal muscle cell; and vulval cell. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is an ortholog of human CSK (C-terminal Src kinase).
ubc-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Contributes to ubiquitin-protein transferase activity. Involved in protein ubiquitination and regulation of protein localization to cell surface. Part of ubiquitin conjugating enzyme complex. Expressed in several structures, including intestinal cell. Is an ortholog of human UBE2N (ubiquitin conjugating enzyme E2 N) and UBE2NL (ubiquitin conjugating enzyme E2 N like (gene/pseudogene)).
egl-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell fate commitment; regulation of DNA-templated transcription; and vulval development. Located in nucleus. Expressed in several structures, including developing hermaphrodite gonad; egg-laying apparatus; intestinal cell; neurons; and uterine pi cell. Human ortholog(s) of this gene implicated in high grade glioma. Is an ortholog of human SOX13 (SRY-box transcription factor 13); SOX5 (SRY-box transcription factor 5); and SOX6 (SRY-box transcription factor 6).
vha-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in lysosomal lumen acidification. Predicted to be part of proton-transporting V-type ATPase, V1 domain. Expressed in head. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IID and developmental and epileptic encephalopathy 93. Is an ortholog of human ATP6V1A (ATPase H+ transporting V1 subunit A).
set-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in MSpaaapa; germ line; and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including
daf-2;
eat-2; and
pgl-1 based on microarray; tiling array; and RNA-seq studies. Is affected by eleven chemicals including Alovudine; stavudine; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: SET domain superfamily and SET domain.
rps-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable small ribosomal subunit rRNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of cytosolic small ribosomal subunit and small-subunit processome. Is an ortholog of human RPS13 (ribosomal protein S13).
dhs-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable carbonyl reductase (NADPH) activity. Is an ortholog of human DHRS2 (dehydrogenase/reductase 2); DHRS4 (dehydrogenase/reductase 4); and DHRS4L2 (dehydrogenase/reductase 4 like 2).
kin-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Expressed in intestine; pharynx; and tail.
dhs-22 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 13 and Leber hereditary optic neuropathy. Is an ortholog of several human genes including RDH11 (retinol dehydrogenase 11); RDH12 (retinol dehydrogenase 12); and RDH13 (retinol dehydrogenase 13).
mig-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in positive regulation of cell migration. Located in axon; neuronal cell body; and plasma membrane. Expressed in several structures, including QR.a; QR.p; QR.pa; body ganglion; and somatic neurons.
inx-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable gap junction channel activity. Involved in positive regulation of nematode male tail tip morphogenesis. Predicted to be located in gap junction and plasma membrane. Expressed in several structures, including CAN; amphid sheath cell; ganglia; pharyngeal motor neurons; and tail hypodermis.
sra-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables olfactory receptor activity. Involved in several processes, including detection of chemical stimulus involved in sensory perception of smell; negative regulation of response to food; and negative regulation of vulval development. Predicted to be located in membrane. Expressed in amphid neurons; body wall musculature; head; hypodermis; and muscle cell.
prx-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in nematode larval development. Predicted to be located in peroxisomal membrane. Predicted to be part of peroxisomal importomer complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 11A. Is an ortholog of human PEX13 (peroxisomal biogenesis factor 13).
arl-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity and GTPase activity. Involved in cilium organization; receptor localization to non-motile cilium; and sensory perception of chemical stimulus. Acts upstream of or within motile cilium assembly. Located in plasma membrane bounded cell projection. Expressed in ciliated neurons and head. Used to study Joubert syndrome. Human ortholog(s) of this gene implicated in Joubert syndrome 8. Is an ortholog of human ARL13B (ADP ribosylation factor like GTPase 13B).
che-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in chemosensory behavior; cilium organization; and protein localization. Located in axoneme; ciliary basal body; and ciliary transition zone. Part of intraciliary transport particle B. Expressed in neurons. Used to study ciliopathy. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Is an ortholog of human IFT57 (intraflagellar transport 57).
flor-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex.
his-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Predicted to be part of nucleosome. Is an ortholog of several human genes including H3C1 (H3 clustered histone 1); H3C3 (H3 clustered histone 3); and H3C4 (H3 clustered histone 4).
kin-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein serine/threonine kinase activity. Involved in response to hermaphrodite contact and vulval location. Located in neuronal cell body; nucleus; and plasma membrane bounded cell projection. Part of protein kinase CK2 complex. Expressed in oocyte. Human ortholog(s) of this gene implicated in breast cancer. Is an ortholog of human CSNK2A1 (casein kinase 2 alpha 1) and CSNK2A3 (casein kinase 2 alpha 3).
skr-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1).
atg-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in mitophagy; piecemeal microautophagy of the nucleus; and protein localization to phagophore assembly site. Predicted to be located in cytosol and phagophore assembly site. Predicted to be part of Atg1/ULK1 kinase complex. Expressed in body wall musculature; nerve ring; neurons; and pharyngeal muscle cell. Is an ortholog of human ATG13 (autophagy related 13).
gly-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity. Predicted to be involved in protein N-linked glycosylation. Located in perinuclear region of cytoplasm. Expressed in several structures, including ganglia; intestine; muscle cell; ventral nerve cord; and vulva. Is an ortholog of human MGAT1 (alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase).
D2045.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10); KCTD13 (potassium channel tetramerization domain containing 13); and TNFAIP1 (TNF alpha induced protein 1).
K02F6.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein homooligomerization. Is an ortholog of human KCTD10 (potassium channel tetramerization domain containing 10); KCTD13 (potassium channel tetramerization domain containing 13); and TNFAIP1 (TNF alpha induced protein 1).
trpp-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in trans-Golgi network. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 13. Is an ortholog of human TRAPPC9 (trafficking protein particle complex subunit 9).
taf-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein heterodimerization activity. Predicted to be involved in transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 60. Is an ortholog of human TAF13 (TATA-box binding protein associated factor 13).
str-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Located in non-motile cilium.
dyf-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary anterograde transport and intraciliary transport involved in cilium assembly. Predicted to be located in ciliary basal body and ciliary base. Predicted to be part of intraciliary transport particle B. Expressed in neurons. Is an ortholog of human IFT56 (intraflagellar transport 56).
nhr-114 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in regulation of gene expression. Acts upstream of with a positive effect on S-adenosylmethionine cycle. Located in nucleus. Expressed in germ line; hypodermis; and intestine. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human NR1H3 (nuclear receptor subfamily 1 group H member 3).
aka-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in endosomal transport. Predicted to be located in early endosome membrane. Is an ortholog of human ZFYVE9 (zinc finger FYVE-type containing 9).
M106.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 15-oxoprostaglandin 13-oxidase activity. Predicted to be involved in prostaglandin metabolic process. Predicted to be located in cytoplasm. Expressed in head and tail. Is an ortholog of human PTGR2 (prostaglandin reductase 2).
usp-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable cysteine-type deubiquitinase activity. Predicted to be involved in proteolysis. Predicted to be located in cytosol and nucleus. Is an ortholog of human USP13 (ubiquitin specific peptidase 13) and USP5 (ubiquitin specific peptidase 5).
Cbn-kin-19 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
Cjp-kin-19 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
Ovo-kin-19 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
Bma-kin-19 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
Cre-kin-19 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
OVOC8481 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
Cbr-kin-19 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
Cre-kin-29 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-29. In C. elegans,
kin-29 is involved in several processes, including dauer entry; positive regulation of growth rate; and transforming growth factor beta receptor signaling pathway.
imp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables aspartic endopeptidase activity, intramembrane cleaving. Involved in ecdysis, collagen and cuticulin-based cuticle; proteolysis; and regulation of multicellular organismal development. Predicted to be located in endoplasmic reticulum membrane. Is an ortholog of human HM13 (histocompatibility minor 13).
Ppa-kin-19 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-19. In C. elegans,
kin-19 is involved in Wnt signaling pathway, regulating spindle positioning and positive regulation of proteasomal ubiquitin-dependent protein catabolic process.
dhhc-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable palmitoyltransferase activity. Predicted to be located in Golgi membrane. Expressed in body wall musculature and neurons. Is an ortholog of human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13) and ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17).
Cbr-kin-29 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-29. In C. elegans,
kin-29 is involved in several processes, including dauer entry; positive regulation of growth rate; and transforming growth factor beta receptor signaling pathway.
Cbn-kin-29 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-29. In C. elegans,
kin-29 is involved in several processes, including dauer entry; positive regulation of growth rate; and transforming growth factor beta receptor signaling pathway.
Cjp-kin-29 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
kin-29. In C. elegans,
kin-29 is involved in several processes, including dauer entry; positive regulation of growth rate; and transforming growth factor beta receptor signaling pathway.
ints-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in centrosome localization and regulation of mitotic cell cycle. Predicted to be located in nucleus and perinuclear region of cytoplasm. Predicted to be part of integrator complex. Is an ortholog of human INTS13 (integrator complex subunit 13).
dmsr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables neuropeptide receptor activity. Involved in regulation of cellular response to heat and regulation of circadian sleep/wake cycle, sleep. Located in neuronal cell body membrane. Expressed in AIY; RID; and tail neurons.
nas-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in extracellular region. Expressed in IL2L; IL2R; and amphid neurons. Is an ortholog of human ASTL (astacin like metalloendopeptidase).
T16G12.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tRNA binding activity. Predicted to be involved in tRNA re-export from nucleus. Predicted to be located in cytoplasm and nuclear matrix. Predicted to be part of nuclear pore. Is an ortholog of human IPO13 (importin 13).
nac-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables low-affinity sodium:dicarboxylate symporter activity and succinate transmembrane transporter activity. Involved in succinate transport. Predicted to be located in membrane. Expressed in alimentary system. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 25. Is an ortholog of human SLC13A2 (solute carrier family 13 member 2) and SLC13A5 (solute carrier family 13 member 5).
prp-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable pre-mRNA intronic binding activity and snRNA binding activity. Predicted to be involved in spliceosomal tri-snRNP complex assembly. Predicted to be located in nucleus. Predicted to be part of U5 snRNP and catalytic step 2 spliceosome. Expressed in germ line. Used to study retinitis pigmentosa 13. Human ortholog(s) of this gene implicated in retinitis pigmentosa 13. Is an ortholog of human PRPF8 (pre-mRNA processing factor 8).
PPA06809 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13.
R09D1.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and prostate cancer. Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3).
SRAE_2000227700 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Vacuolar protein sorting-associated protein 13, SHR-binding domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
CBG02475 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
SRAE_2000242500 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
OVOC11000 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
TMUE_1000003295 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans C25H3.11.
CJA13673 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans T08G11.1.
PPA19529 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.9.
SRAE_1000346500 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
dcaf-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleolus. Predicted to be part of small-subunit processome. Is an ortholog of human DCAF13 (DDB1 and CUL4 associated factor 13).
glb-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable several functions, including heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Expressed in head; somatic nervous system; and tail neurons.
CBG12391 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
CRE29770 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
OVOC483 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
TMUE_1000004346 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
CJA08825 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans C25H3.11.
snu-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome; maturation of LSU-rRNA; and maturation of SSU-rRNA. Predicted to be located in nucleolus. Predicted to be part of ribonucleoprotein complex. Is an ortholog of human SNU13 (small nuclear ribonucleoprotein 13).
CBN29394 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans C25H3.11.
CRE11977 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Ricin B-like lectins; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans C25H3.11.
Bm5678 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
Bm2384 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Ricin B-like lectins; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13, VPS13 adaptor binding domain; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
SRAE_1000288200 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Predicted to enable protein tyrosine kinase activity. Is an ortholog of C. elegans
daf-2 and members of the C. elegans ver and kin gene classes including
ver-3 and
kin-15. In C. elegans,
daf-2 is involved in several processes, including dauer exit; regulation of developmental process; and regulation of macromolecule metabolic process.
TMUE_1000005019 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable protein tyrosine kinase activity. Is an ortholog of C. elegans
daf-2 and members of the C. elegans ver and kin gene classes including
ver-3 and
kin-15. In C. elegans,
daf-2 is involved in several processes, including dauer exit; regulation of developmental process; and regulation of macromolecule metabolic process.
PPA43957 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Autophagy-related protein C terminal domain; Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Autophagy-related, C-terminal; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; SHR-binding domain of vacuolar-sorting associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
TMUE_1000003292 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13-like, N-terminal domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal.
CBN15531 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Autophagy-related protein C terminal domain; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Autophagy-related, C-terminal; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans T08G11.1.
CBN29401 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Vacuolar-sorting-associated 13 protein C-terminal; Autophagy-related protein C terminal domain; Vacuolar protein sorting-associated protein 13, SHR-binding domain; Autophagy-related, C-terminal; Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, C-terminal; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans T08G11.1.
Ppa-kin-2 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; and RmlC-like jelly roll fold. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
TMUE_2000010143 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Cyclic nucleotide-binding domain; Cyclic nucleotide-binding-like; and RmlC-like jelly roll fold. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
tctn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in cilium assembly. Predicted to be located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital syndrome IV. Is an ortholog of human TCTN1 (tectonic family member 1) and TCTN3 (tectonic family member 3).
tin-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metal ion binding activity. Predicted to be involved in protein insertion into mitochondrial inner membrane. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial intermembrane space protein transporter complex. Is an ortholog of human TIMM13 (translocase of inner mitochondrial membrane 13).
nhr-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in intestine.
gcy-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Predicted to be involved in cGMP biosynthetic process and receptor guanylyl cyclase signaling pathway. Predicted to be located in plasma membrane. Expressed in RIML; RIMR; and nervous system.
Y50D4B.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in membrane. Predicted to be part of receptor complex. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and prostate cancer. Is an ortholog of human FLT3 (fms related receptor tyrosine kinase 3).
Bma-kin-2 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
Cbr-kin-2 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
SRAE_X000072000 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
CRE11978 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13-like, N-terminal domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
Cbn-kin-2 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
Cre-kin-2 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
Ovo-kin-2 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
CBN25792 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13-like, N-terminal domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
tag-196 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in protein catabolic process. Predicted to be located in extracellular space. Expressed in intestine and tail. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 13. Is an ortholog of human CTSF (cathepsin F).
Cjp-kin-2 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable cAMP-dependent protein kinase regulator activity. Predicted to be involved in regulation of protein phosphorylation. Predicted to be part of cAMP-dependent protein kinase complex. Is an ortholog of C. elegans
kin-2. In C. elegans,
kin-2 is involved in several processes, including medium-term memory; negative regulation of oocyte maturation; and negative regulation of protein kinase C signaling.
CBN01346 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13-like, N-terminal domain; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; Vacuolar protein sorting-associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans C25H3.11.
CBN29682 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13; Vacuolar protein sorting-associated protein 13, SHR-binding domain; and SHR-binding domain of vacuolar-sorting associated protein 13. Is an ortholog of C. elegans C25H3.11.
kin-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein tyrosine kinase activity. Predicted to be involved in phosphorylation. Expressed in head neurons; marginal cell; pharyngeal muscle cell; pharyngeal-intestinal valve; and tail neurons. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Is an ortholog of human FER (FER tyrosine kinase) and FES (FES proto-oncogene, tyrosine kinase).
str-220 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled olfactory receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and olfactory behavior. Predicted to be located in membrane. Expressed in AWBL and AWBR.
rpl-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of cytosolic large ribosomal subunit. Is an ortholog of human RPL13 (ribosomal protein L13).
vps-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in protein retention in Golgi apparatus and protein targeting to vacuole. Predicted to be extrinsic component of membrane. Expressed in vulval muscle. Human ortholog(s) of this gene implicated in Parkinson's disease 23; choreaacanthocytosis; and choreatic disease. Is an ortholog of human VPS13A (vacuolar protein sorting 13 homolog A).
Y55F3AM.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in germ line; rectal epithelial cell; rectum; and somatic gonad precursor based on proteomic; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
daf-2; and
skn-1 based on microarray; proteomic; and RNA-seq studies. Is affected by six chemicals including Rifampin; allantoin; and Capsaicin based on RNA-seq; proteomic; and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.
ndx-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable NADH pyrophosphatase activity. Predicted to be involved in NAD catabolic process; NADH metabolic process; and NADP catabolic process. Predicted to be located in peroxisome. Is an ortholog of human NUDT13 (nudix hydrolase 13).
F42A6.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable Hsp70 protein binding activity and nuclear import signal receptor activity. Predicted to be involved in protein import into nucleus. Predicted to be located in cytosol and nucleus. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 13. Is an ortholog of human HIKESHI (heat shock protein nuclear import factor hikeshi).
Ighl16 [Search on AGR]
Rattus norvegicus Orthologous to human IGHV3OR16-13 (immunoglobulin heavy variable 3/OR16-13 (non-functional)); INTERACTS WITH 17beta-hydroxy-5alpha-androstan-3-one (ortholog); dimethylarsinic acid (ortholog); methylarsonic acid (ortholog).
zipt-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in intracellular zinc ion homeostasis and zinc ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome spondylodysplastic type 3. Is an ortholog of human SLC39A13 (solute carrier family 39 member 13).
CJA19200 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Vacuolar protein sorting-associated protein 13-like, N-terminal domain; Repeating coiled region of VPS13; N-terminal region of Chorein or VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal. Is an ortholog of C. elegans T08G11.1.
PPA36091 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Ribosomal protein S7 domain superfamily; Repeating coiled region of VPS13; Vacuolar protein sorting-associated protein 13, second N-terminal domain; VPS13, repeated coiled region; Vacuolar protein sorting-associated protein 13; and Vacuolar sorting-associated protein 13, N-terminal.
dpy-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be a structural constituent of cuticle. Involved in cuticle development involved in collagen and cuticulin-based cuticle molting cycle. Located in collagen and cuticulin-based cuticle extracellular matrix.
C25H3.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable glycosyltransferase activity and metal ion binding activity. Predicted to be involved in mitochondrion organization; protein retention in Golgi apparatus; and protein targeting to vacuole. Predicted to be extrinsic component of membrane. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 4. Is an ortholog of human VPS13D (vacuolar protein sorting 13 homolog D).
Pex13 [Search on AGR]
Drosophila melanogaster Peroxin 13 (Pex13) encodes a peroxisome protein important for sperm development.