sos-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including epidermal growth factor receptor signaling pathway; female gamete generation; and positive regulation of vulval development. Predicted to be located in plasma membrane. Human ortholog(s) of this gene implicated in several diseases, including Noonan syndrome 4; Noonan syndrome 9; and reproductive organ cancer (multiple). Is an ortholog of human SOS1 (SOS Ras/Rac guanine nucleotide exchange factor 1).