Predicted to be an extracellular matrix structural constituent. Involved in several processes, including basement membrane organization; generation of neurons; and response to misfolded protein. Located in basement membrane. Expressed in several structures, including anal depressor muscle; basal lamina; body wall musculature; egg-laying apparatus; and intestine. Human ortholog(s) of this gene implicated in familial nephrotic syndrome; junctional epidermolysis bullosa; and lung small cell carcinoma. Is an ortholog of human LAMA5 (laminin subunit alpha 5).
Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds. Predicted to be involved in carbohydrate metabolic process. Expressed in somatic cell.
Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in ketone body biosynthetic process and leucine catabolic process. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Is an ortholog of human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase) and HMGCLL1 (3-hydroxy-3-methylglutaryl-CoA lyase like 1).