• mcm-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable single-stranded DNA binding activity. Predicted to contribute to single-stranded DNA helicase activity. Involved in gonad development; locomotion; and nervous system development. Located in nucleus. Expressed in several structures, including P lineage cell; Q lineage cell; Z2; somatic gonad precursor; and sperm. Human ortholog(s) of this gene implicated in immunodeficiency 54. Is an ortholog of human MCM4 (minichromosome maintenance complex component 4).
  • sle-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development and mitotic cell cycle.
  • stu-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development; mitotic cell cycle; and vulval development.
  • stu-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development; mitotic cell cycle; and vulval development.
  • stu-17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within embryo development; mitotic cell cycle; and vulval development.
  • str-58 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-14 and lin-4 based on microarray studies.
  • F38H4.16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-14 and lin-4 based on microarray studies.
  • T12B5.18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by sir-2.1; lin-14; and lin-4 based on microarray studies.
  • suv-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • eif-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ribosomal large subunit binding activity. Involved in miRNA-mediated gene silencing. Predicted to be located in cytosol and nucleolus. Predicted to be part of preribosome, large subunit precursor. Used to study obesity. Is an ortholog of human EIF6 (eukaryotic translation initiation factor 6).
  • F39E9.19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies.
  • F39E9.20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies.
  • F39E9.25 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by lin-14 and lin-4 based on microarray studies.
  • Y51A2A.18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-14 and lin-4 based on microarray studies. Is affected by Atrazine based on microarray studies.
  • srh-86 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and clk-1 based on microarray and RNA-seq studies.
  • srx-91 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies.
  • T04A11.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-16; lin-4; and lin-14 based on RNA-seq and microarray studies.
  • clec-248 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and cnd-1 based on tiling array; RNA-seq; and microarray studies.
  • math-11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and clk-1 based on tiling array; microarray; and RNA-seq studies.
  • C33A12.16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by clk-1; lin-14; and lin-4 based on microarray studies. Is affected by resveratrol and Sirolimus based on microarray studies.
  • lin-28 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA binding activity and enzyme binding activity. Involved in several processes, including regulation of cell fate specification; regulation of development, heterochronic; and regulation of gene expression. Located in cytoplasm and nucleus. Expressed in germ line; hypodermis; muscle cell; nervous system; and neurons. Is an ortholog of human LIN28A (lin-28 homolog A).
  • lin-15A [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in several processes, including negative regulation of vulval development; protein stabilization; and vulval development. Located in nucleus. Expressed in gonad.
  • lin-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables mRNA 3'-UTR binding activity. Involved in several processes, including egg-laying behavior; mating; and negative regulation of gene expression. Part of polysome. Expressed in several structures, including P5.p hermaphrodite; P7.p hermaphrodite; gonad; neurons; and ventral nerve cord.
  • lin-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • F39E9.21 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD and intestine based on RNA-seq and microarray studies. Is affected by lin-14 and lin-4 based on microarray studies.
  • lin-38 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in negative regulation of vulval development.
  • lin-56 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in several processes, including protein localization to nucleus; protein stabilization; and vulval development. Located in nucleus. Expressed in somatic cell.
  • ZK673.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable metal ion binding activity.
  • lin-53 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables histone deacetylase binding activity. Involved in several processes, including cell fate specification; embryonic digestive tract morphogenesis; and nematode male tail tip morphogenesis. Acts upstream of or within mitochondrial unfolded protein response. Located in nucleus. Part of DRM complex and NuRD complex. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P5.p hermaphrodite; P7.p hermaphrodite; and P8.p hermaphrodite. Is an ortholog of human RBBP4 (RB binding protein 4, chromatin remodeling factor) and RBBP7 (RB binding protein 7, chromatin remodeling factor).
  • ets-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in negative regulation of vulval development.
  • Y32B12B.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in negative regulation of vulval development.
  • lin-54 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Located in autosome and condensed nuclear chromosome. Part of DRM complex. Expressed in several structures, including pharynx and vulva. Is an ortholog of human LIN54 (lin-54 DREAM MuvB core complex component) and TESMIN (testis expressed metallothionein like protein).
  • srbc-80 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; eat-2; and lin-14 based on RNA-seq and microarray studies. Is affected by Sirolimus based on RNA-seq studies.
  • srw-114 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray studies. Is affected by adsorbable organic bromine compound and allantoin based on microarray studies.
  • pph-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable protein serine/threonine phosphatase activity. Involved in cortical actin cytoskeleton organization; establishment of mitotic spindle localization; and first cell cycle pseudocleavage. Located in astral microtubule and cell cortex. Is an ortholog of human PPP6C (protein phosphatase 6 catalytic subunit).
  • lin-31 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables sequence-specific DNA binding activity. Involved in vulval development. Located in nucleus. Expressed in several structures, including P11.p; P9.p; gonad; nerve ring; and vulval precursor cell. Is an ortholog of human FOXB2 (forkhead box B2).
  • F19F10.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable kinase activity. Predicted to be involved in negative regulation of vulval development and phosphorylation.
  • lin-27 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • lin-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables protein-macromolecule adaptor activity and signaling receptor binding activity. Involved in several processes, including egg-laying behavior; positive regulation of vulval development; and protein localization to basolateral plasma membrane. Located in cell-cell junction. Expressed in gonad; head; somatic gonad precursor; somatic nervous system; and vulval precursor cell. Is an ortholog of human LIN7A (lin-7 homolog A, crumbs cell polarity complex component); LIN7B (lin-7 homolog B, crumbs cell polarity complex component); and LIN7C (lin-7 homolog C, crumbs cell polarity complex component).
  • srb-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-12; lin-4; and lin-14 based on tiling array and microarray studies. Is affected by five chemicals including resveratrol; Atrazine; and Chlorpyrifos based on microarray studies.
  • rsp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable mRNA binding activity. Involved in gonad development and regulation of termination of DNA-templated transcription. Located in nucleus. Expressed in several structures, including PVDL and PVDR. Human ortholog(s) of this gene implicated in bipolar disorder; clear cell renal cell carcinoma; and ovary epithelial cancer. Is an ortholog of human SRSF7 (serine and arginine rich splicing factor 7).
  • F47G4.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by several genes including pie-1; lin-4; and lin-14 based on RNA-seq and microarray studies. Is affected by Cholestanol based on microarray studies.
  • lin-65 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in chromatin remodeling and mitochondrial unfolded protein response. Located in cytosol and nucleus. Expressed in head neurons and intestine.
  • F15H10.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-15B; dpy-21; and lin-37 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies.
  • lin-46 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable molecular adaptor activity and molybdopterin molybdotransferase activity. Involved in regulation of development, heterochronic. Located in cytoplasm and nucleus. Expressed in hypodermis; seam cell; and vulval precursor cell.
  • mau-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • lin-25 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in defense response to Gram-positive bacterium and vulval development. Acts upstream of or within with a positive effect on cell fate specification. Located in cytoplasm and nucleus. Expressed in several structures, including P3.p hermaphrodite; P4.p hermaphrodite; P8.p hermaphrodite; hermaphrodite distal tip cell; and vulval cell.
  • srab-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.
  • sas-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in centriole and cytoplasm.
  • lin-52 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in embryo development; negative regulation of signal transduction; and regulation of neurogenesis. Predicted to be located in nucleus. Predicted to be part of DRM complex. Expressed in AS neuron; anal depressor muscle; chemosensory neurons; excretory cell; and intestine. Is an ortholog of human LIN52 (lin-52 DREAM MuvB core complex component).
  • C55B6.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in NSM; hypodermis; muscle cell; and neurons based on tiling array; RNA-seq; and microarray studies. Is affected by several genes including daf-12; lin-4; and lin-14 based on microarray and tiling array studies.
  • F28A10.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; eat-2; and lin-14 based on RNA-seq and microarray studies. Is affected by six chemicals including glycine; Doxycycline; and paraquat based on RNA-seq and microarray studies.
  • H40L08.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by dpy-21; thoc-5; and lin-29 based on RNA-seq studies.
  • lin-62 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • srh-278 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in NSM based on tiling array studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on tiling array; RNA-seq; and microarray studies. Is affected by Sirolimus based on microarray studies.
  • T21G5.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray studies. Is affected by five chemicals including resveratrol; Chlorpyrifos; and paraquat based on microarray studies.
  • lin-14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and single-stranded DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; regulation of cell fate specification; and regulation of nematode larval development, heterochronic. Located in condensed nuclear chromosome. Expressed in several structures, including QL; QR; neurons; oocyte; and somatic nervous system.
  • let-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within nematode larval development.
  • lsy-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • irld-26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain.
  • math-25 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and smn-1 based on tiling array; RNA-seq; and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like.
  • F26F2.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-35; nhr-49; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by six chemicals including Mercuric Chloride; Psoralens; and allantoin based on microarray and RNA-seq studies.
  • amo-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • lin-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA binding activity. Involved in embryo development; male sex differentiation; and regulation of multicellular organismal development. Part of DRM complex. Is an ortholog of human LIN9 (lin-9 DREAM MuvB core complex component).
  • lin-41 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables mRNA binding activity and translation repressor activity. Involved in several processes, including negative regulation of gene expression; regulation of developmental process; and reproductive process. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Located in cytoplasm. Part of messenger ribonucleoprotein complex. Expressed in several structures, including germ cell; hypodermal cell; intestine; neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in hydrocephalus. Is an ortholog of human TRIM71 (tripartite motif containing 71).
  • glb-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables heme binding activity; iron ion binding activity; and oxygen binding activity. Predicted to be involved in oxygen transport and response to hypoxia. Expressed in neurons and somatic nervous system.
  • cps-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables endonuclease activity; protein homodimerization activity; and sequence-specific DNA binding activity. Involved in RNA catabolic process and apoptotic DNA fragmentation. Located in mitochondrion. Is an ortholog of human ENDOG (endonuclease G).
  • Y57G11C.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable 6-phosphogluconolactonase activity. Predicted to be involved in pentose-phosphate shunt, oxidative branch. Located in nucleus. Expressed in germ cell. Is an ortholog of human PGLS (6-phosphogluconolactonase).
  • Y57E12B.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Ag nanoparticles; and single-walled carbon nanotube based on microarray and RNA-seq studies.
  • F02D10.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-28; hmg-3; and daf-2 based on RNA-seq and microarray studies.
  • mes-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to contribute to nucleosome binding activity. Involved in regulation of gene expression. Part of PcG protein complex and nucleosome. Expressed in Z2; Z3; germ line; intestinal cell; and oocyte. Is an ortholog of human EED (embryonic ectoderm development).
  • vab-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • rax-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • dpy-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables calmodulin binding activity.
  • lin-16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • F12F6.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-29; set-2; and emr-1 based on RNA-seq studies.
  • 21ur-10109 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-29; set-2; and lem-2 based on RNA-seq studies.
  • vet-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in gastrulation. Located in cytoplasm.
  • B0507.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-35; isp-1; and lin-15B based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.
  • C49G7.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is affected by sucrose and stearic acid based on RNA-seq studies. Is predicted to encode a protein with the following domain: CUB-like domain.
  • C14E2.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on tiling array; RNA-seq; and microarray studies. Is affected by four chemicals including Rifampin; allantoin; and Sirolimus based on RNA-seq studies.
  • 21ur-10648 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • 21ur-14833 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • 21ur-11815 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • ZK328.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • MTCE.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • Y71A12B.26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • lin-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables sequence-specific DNA binding activity. Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including egg-laying behavior; negative regulation of transcription by RNA polymerase II; and vulval development. Located in nucleus. Part of RNA polymerase II transcription repressor complex. Expressed in vulval precursor cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Huntington's disease; Lewy body dementia; and schizophrenia. Is an ortholog of human ELK1 (ETS transcription factor ELK1).
  • K10G6.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies.
  • fer-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • math-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-14 and lin-4 based on microarray studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like.
  • F15H10.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including lin-35; lin-15B; and met-2 based on microarray and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.
  • W09C5.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AVE; intestine; and ventral nerve cord based on tiling array and microarray studies. Is affected by several genes including daf-16; lin-4; and lin-14 based on microarray and RNA-seq studies. Is affected by adsorbable organic bromine compound based on microarray studies.
  • T14B4.19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in male-specific anatomical entity based on microarray studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is affected by nine chemicals including Atrazine; cadmium; and Quercetin based on microarray and RNA-seq studies.
  • sli-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • lin-26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including establishment or maintenance of epithelial cell apical/basal polarity; tissue development; and vulval development. Located in nucleus. Expressed in several structures, including Z2; epithelial cell; germ line; gonad; and somatic gonad precursor.
  • Y82E9BR.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in male based on RNA-seq studies. Is affected by lin-15B and daf-2 based on microarray studies.
  • F35E8.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; eat-2; and lin-35 based on microarray and RNA-seq studies.
  • T08G5.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-35; alg-1; and lagr-1 based on RNA-seq and microarray studies.
  • pfkb-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).
  • pfkb-1.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).
  • such-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • C53A3.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including mut-2; mir-35; and lin-54 based on RNA-seq and microarray studies.
  • srh-188 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; lin-52; and etr-1 based on RNA-seq and microarray studies.
  • W08F4.20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including mut-2; lin-54; and tdp-1 based on RNA-seq and microarray studies.
  • mcd-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable metal ion binding activity. Involved in nematode larval development; positive regulation of growth rate; and programmed cell death.
  • B0547.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; lin-4; and lin-14 based on tiling array and microarray studies. Is affected by adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function (DUF545) and SPK domain.
  • odr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • lin-42 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA polymerase II-specific DNA-binding transcription factor binding activity. Involved in negative regulation of dauer larval development; negative regulation of miRNA transcription; and regulation of development, heterochronic. Located in cytoplasm and nucleus. Expressed in head; hyp7 syncytium; and pharyngeal muscle cell. Human ortholog(s) of this gene implicated in advanced sleep phase syndrome 1. Is an ortholog of human PER1 (period circadian regulator 1) and PER2 (period circadian regulator 2).
  • B0524.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-12; dpy-21; and lin-22 based on tiling array and RNA-seq studies.
  • F46F2.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD based on RNA-seq studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by seven chemicals including multi-walled carbon nanotube; metformin; and Psoralens based on RNA-seq and microarray studies.
  • srpr-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in DD neuron based on microarray studies. Is affected by several genes including lin-4; lin-14; and cep-1 based on RNA-seq and microarray studies. Is affected by four chemicals including Tunicamycin; multi-walled carbon nanotube; and single-walled carbon nanotube based on RNA-seq and microarray studies.
  • lin-61 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable chromatin binding activity and methylated histone binding activity. Involved in vulval development. Located in nucleus. Part of chromatin. Expressed widely. Is an ortholog of human L3MBTL2 (L3MBTL histone methyl-lysine binding protein 2) and MBTD1 (mbt domain containing 1).
  • F58E1.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD and NSM based on tiling array and RNA-seq studies. Is affected by several genes including let-60; lin-4; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by ten chemicals including rotenone; Psoralens; and allantoin based on RNA-seq and microarray studies.
  • 21ur-3731 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by efa-6 and set-2 based on RNA-seq studies.
  • 21ur-5057 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 and cpl-1 based on RNA-seq studies.
  • K04D7.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by cep-1 and rnp-6 based on RNA-seq studies.
  • T22D1.22 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 and nfki-1 based on RNA-seq studies.
  • lin-15B [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA binding activity and metal ion binding activity. Involved in negative regulation of Ras protein signal transduction; negative regulation of vulval development; and regulation of cell fate specification. Expressed in several structures, including anterior gonad arm; oocyte; and somatic cell.
  • irld-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; lin-15B; and cyc-1 based on microarray; tiling array; and RNA-seq studies.
  • 21ur-3208 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by hmg-3 and rnp-6 based on RNA-seq studies.
  • F15H9.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by sftb-1 and rnp-6 based on RNA-seq studies.
  • 21ur-15248 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 and cpl-1 based on RNA-seq studies.
  • lin-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables dynein complex binding activity. Involved in several processes, including gonad development; microtubule cytoskeleton organization; and regulation of protein localization. Located in cell cortex; condensed chromosome; and spindle.
  • 21ur-4346 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by hpl-2 and rnp-6 based on RNA-seq studies.
  • B0334.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by hda-6 and ptl-1 based on RNA-seq studies.
  • K10H10.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by hda-6 and ptl-1 based on RNA-seq studies.
  • Y40B10A.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 and csr-1 based on RNA-seq studies.
  • sas-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables identical protein binding activity and protein domain specific binding activity. Involved in centriole replication; protein localization; and regulation of cell cycle. Located in centriole and cytoplasm.
  • ubxn-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in cytoplasm. Expressed in pharynx. Is an ortholog of human UBXN6 (UBX domain protein 6).
  • C28H8.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons; pharyngeal-intestinal valve; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and clk-1 based on microarray and RNA-seq studies. Is affected by Alovudine; resveratrol; and Atrazine based on RNA-seq and microarray studies.
  • linc-131 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by dpy-21 and rnp-6 based on RNA-seq studies.
  • MTCE.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by prg-1 and rnp-6 based on RNA-seq studies.
  • lin-40 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable histone deacetylase binding activity; transcription coactivator activity; and transcription corepressor activity. Acts upstream of or within chromatin organization; mitochondrial unfolded protein response; and positive regulation of protein localization to nucleus. Located in nucleus. Part of NuRD complex. Expressed in distal tip cell and somatic cell. Is an ortholog of human MTA1 (metastasis associated 1) and MTA3 (metastasis associated 1 family member 3).
  • ptr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in molting cycle. Predicted to be located in cytoplasmic vesicle membrane and plasma membrane. Expressed in anterior hypodermis.
  • srz-68 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in ADL based on single-cell RNA-seq studies. Is affected by etr-1 and lin-52 based on RNA-seq studies.
  • pbo-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables extracellular ligand-gated monoatomic ion channel activity. Predicted to be involved in monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in body wall musculature.
  • pfd-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable protein-folding chaperone binding activity. Predicted to be involved in chaperone-mediated protein complex assembly and protein folding. Located in cytoplasm. Expressed in body wall musculature; hypodermal cell; intestinal cell; and non-striated muscle. Is an ortholog of human PFDN6 (prefoldin subunit 6).
  • mua-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be a structural constituent of cytoskeleton. Involved in cell-cell adhesion. Located in hemidesmosome. Expressed in hypodermis; touch receptor neurons; uterus; and ventral cord neurons. Human ortholog(s) of this gene implicated in partial lipodystrophy; primary autosomal recessive microcephaly; and progressive myoclonus epilepsy 9. Is an ortholog of human LMNB2 (lamin B2).
  • gfat-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Predicted to be involved in UDP-N-acetylglucosamine metabolic process and fructose 6-phosphate metabolic process. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12; obesity; and type 2 diabetes mellitus. Is an ortholog of human GFPT1 (glutamine--fructose-6-phosphate transaminase 1).
  • coq-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable oxidoreductase activity. Involved in ubiquinone biosynthetic process. Predicted to be located in mitochondrion. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 6. Is an ortholog of human COQ6 (coenzyme Q6, monooxygenase).
  • mab-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • fbxa-160 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-35; lin-15B; and rsr-2 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol and copper sulfate based on microarray studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain.
  • Y52B11A.19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ABplpaapap; ABplpapapa; ABplppppap; ABprpaapap; and ABprpapapa based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including lin-35; lin-15B; and met-2 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.
  • F44E7.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in germ line based on RNA-seq studies. Is affected by iff-1; mys-1; and lin-52 based on RNA-seq studies.
  • lec-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable galactoside binding activity. Located in cytoplasm. Expressed in intestine and pharynx. Is an ortholog of human LGALS7 (galectin 7) and LGALS7B (galectin 7B).
  • lin-17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables receptor tyrosine kinase binding activity. Involved in several processes, including axis specification; cell differentiation; and sex differentiation. Located in neuron projection membrane. Expressed in several structures, including P3.p male; P4.p male; PQR; epithelial cell; and male-specific anatomical entity.
  • 21ur-13767 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6; blmp-1; and cpl-1 based on RNA-seq studies.
  • C05E4.16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6; set-2; and etr-1 based on RNA-seq studies.
  • 21ur-5731 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lem-2; emr-1; and rnp-6 based on RNA-seq studies.
  • 21ur-14806 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by emr-1; lem-2; and rnp-6 based on RNA-seq studies.
  • 21ur-4002 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6; blmp-1; and cpl-1 based on RNA-seq studies.
  • F13B12.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by dlc-1; rnp-6; and camt-1 based on RNA-seq studies.
  • 21ur-975 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lem-2; emr-1; and rnp-6 based on RNA-seq studies.
  • 21ur-9861 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by emr-1; lem-2; and rnp-6 based on RNA-seq studies.
  • C07A12.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by daf-2 and rnp-6 based on microarray and RNA-seq studies.
  • Y111B2A.35 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by daf-2 and rnp-6 based on microarray and RNA-seq studies.
  • H03G16.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including mir-35; crh-1; and lin-54 based on microarray studies. Is affected by resveratrol based on microarray studies.
  • 21ur-1241 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by emr-1; lem-2; and rnp-6 based on RNA-seq studies.
  • 21ur-12912 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lem-2; emr-1; and rnp-6 based on RNA-seq studies.
  • C26H9A.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by set-6; baz-2; and hda-1 based on RNA-seq studies.
  • Y111B2A.36 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by prg-1; rnp-6; and etr-1 based on RNA-seq studies.
  • dlc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable dynein intermediate chain binding activity. Predicted to be involved in microtubule-based process. Predicted to be located in cellular anatomical entity. Predicted to be part of cytoplasmic dynein complex.
  • sup-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-12; rrf-3; and pgl-1 based on tiling array and RNA-seq studies. Is affected by Tunicamycin and sodium arsenite based on RNA-seq studies.
  • sul-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables heparan sulfate 6-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to be located in Golgi stack; cell surface; and endoplasmic reticulum. Is an ortholog of human SULF1 (sulfatase 1) and SULF2 (sulfatase 2).
  • pvl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • sur-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable protein phosphatase regulator activity. Involved in embryo development; nematode larval development; and positive regulation of vulval development. Predicted to be located in cytosol. Predicted to be part of protein phosphatase type 2A complex. Human ortholog(s) of this gene implicated in Alzheimer's disease; breast cancer; spinocerebellar ataxia type 12; and systemic lupus erythematosus. Is an ortholog of human PPP2R2A (protein phosphatase 2 regulatory subunit Balpha) and PPP2R2D (protein phosphatase 2 regulatory subunit Bdelta).
  • cdr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in cytoplasm.
  • egg-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in apical plasma membrane. Expressed in excretory system; neurons; pharynx; rectal epithelial cell; and vulva.
  • abu-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in pharynx development. Expressed in pharyngeal muscle cell.
  • tba-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Predicted to be located in cytoplasm and microtubule. Expressed in HSN; ciliated neurons; intestine; and vulva.
  • acbp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable fatty-acyl-CoA binding activity. Predicted to be involved in fatty acid metabolic process.
  • dsl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable Notch binding activity. Predicted to be involved in cell fate specification. Predicted to be located in membrane.
  • set-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables histone H3K9 dimethyltransferase activity and histone H3K9 trimethyltransferase activity. Predicted to be involved in chromatin remodeling and methylation. Part of chromatin. Expressed in embryonic cell; gonad; muscle cell; nervous system; and sperm. Is an ortholog of human SUV39H2 (SUV39H2 histone lysine methyltransferase).
  • eak-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable protein tyrosine phosphatase activity. Involved in dauer larval development. Located in plasma membrane. Expressed in XXXL and XXXR.
  • ncx-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable calcium:sodium antiporter activity. Predicted to be involved in intracellular calcium ion homeostasis and monoatomic cation transport. Predicted to be located in membrane. Expressed in ADLL and ADLR. Is an ortholog of human SLC8B1 (solute carrier family 8 member B1).
  • haf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATPase-coupled transmembrane transporter activity. Involved in regulatory ncRNA-mediated post-transcriptional gene silencing. Located in perinuclear endoplasmic reticulum. Expressed in germ line; intestine; and muscle cell. Is an ortholog of human ABCB8 (ATP binding cassette subfamily B member 8).
  • rgs-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Human ortholog(s) of this gene implicated in nephrolithiasis. Is an ortholog of human RGS14 (regulator of G protein signaling 14).
  • H05C05.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by several genes including clk-1; pgl-1; and lin-35 based on microarray and RNA-seq studies.
  • F53A3.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by daf-2; rnp-6; and mrps-5 based on microarray and RNA-seq studies.
  • M04F3.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable calcium ion binding activity. Is an ortholog of human PDCD6 (programmed cell death 6).
  • atf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in ATF6-mediated unfolded protein response and positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response. Predicted to be located in nucleus. Expressed in several structures, including intestine; muscle cell; pharyngeal gland cell; rectum; and vulva. Human ortholog(s) of this gene implicated in achromatopsia 7. Is an ortholog of human ATF6 (activating transcription factor 6) and ATF6B (activating transcription factor 6 beta).
  • lin-24 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including germ line; head mesodermal cell; interfacial epithelial cell; neurons; and pharyngeal muscle cell based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-16; skn-1; and hsf-1 based on microarray; tiling array; RNA-seq; and proteomic studies. Is affected by five chemicals including Zidovudine; bortezomib; and paraquat based on RNA-seq and microarray studies.
  • catp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATPase-coupled monoatomic cation transmembrane transporter activity and polyamine transmembrane transporter activity. Involved in protein folding. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including egg-laying apparatus; gonad; oocyte; pharynx; and somatic gonad precursor. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in primary pulmonary hypertension. Is an ortholog of human ATP13A3 (ATPase 13A3).
  • C44B7.20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-29 based on RNA-seq and microarray studies.
  • K10G4.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; pgl-1; and lin-15B based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies.
  • C31G12.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-15B; rsr-2; and flcn-1 based on microarray and tiling array studies. Is affected by Atrazine and dafa#1 based on microarray studies.
  • aqp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables water channel activity. Involved in water transport. Located in neuronal cell body and non-motile cilium. Expressed in IL1 neuron. Is an ortholog of human AQP8 (aquaporin 8).
  • pnm-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • zig-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in homeostatic process. Predicted to be located in neuron projection membrane. Expressed in body wall musculature; enteric muscle; head neurons; and vulval muscle.
  • srf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • T16H12.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including B cell; MSpaaapa; germ line; germline precursor cell; and neurons based on microarray; tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on microarray and RNA-seq studies. Is affected by seven chemicals including rotenone; D-glucose; and stavudine based on RNA-seq and microarray studies.
  • irld-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. Is predicted to encode a protein with the following domains: Receptor L-domain superfamily; Receptor L-domain; and Receptor L domain.
  • arl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables GTPase activity. Involved in intracellular transport. Located in axoneme; cytosol; and dendrite. Expressed in ciliated neurons. Used to study Bardet-Biedl syndrome and ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 1; Bardet-Biedl syndrome 3; and retinitis pigmentosa 55. Is an ortholog of human ARL6 (ADP ribosylation factor like GTPase 6).
  • F22B3.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AVK based on RNA-seq studies. Is affected by several genes including lin-4; lin-14; and fbf-1 based on tiling array; RNA-seq; and microarray studies. Is affected by CGP37157; copper sulfate; and allantoin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; PAN-like domain; and PAN-3 domain.
  • Y82E9BL.19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including eat-2; lin-35; and lin-15B based on RNA-seq studies. Is affected by six chemicals including tryptophan; multi-walled carbon nanotube; and Psoralens based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Domain of unknown function DUF38/FTH, Caenorhabditis species; F-box A protein FB224; and FTH domain.
  • 21ur-2624 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including hsp-6; hpl-2; and numr-1 based on RNA-seq studies.
  • T06C12.16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; ptl-1; and efa-6 based on RNA-seq studies.
  • C08F1.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in muscle cell based on microarray studies. Is affected by several genes including mut-2; lin-54; and hda-2 based on RNA-seq and microarray studies.
  • F27B3.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including lin-35; dpl-1; and efl-1 based on RNA-seq and microarray studies.
  • srh-189 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-16; daf-12; and lin-4 based on microarray and RNA-seq studies. Is affected by resveratrol based on microarray studies.
  • F31C3.16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including atfs-1; nuo-6; and adr-1 based on RNA-seq studies.
  • Y24D9A.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including hsp-6; unc-30; and dlc-1 based on RNA-seq studies.
  • cogc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in gonad morphogenesis and regulation of cell migration. Predicted to be located in Golgi membrane. Predicted to be part of Golgi transport complex. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIl. Is an ortholog of human COG6 (component of oligomeric golgi complex 6).
  • F25B4.16 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by rnp-6 based on RNA-seq studies.
  • math-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ALA; NSM; RIB; amphid sheath cell; and excretory system based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including eat-2; lin-15B; and hsp-6 based on microarray; tiling array; and RNA-seq studies. Is affected by multi-walled carbon nanotube and Alovudine based on RNA-seq studies. Is predicted to encode a protein with the following domains: MATH/TRAF domain; MATH domain; and TRAF-like.
  • F19B10.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including met-2; spr-5; and lin-52 based on RNA-seq studies. Is affected by bortezomib and Tamoxifen based on RNA-seq studies.
  • VT23B5.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; set-2; and lin-22 based on microarray and RNA-seq studies. Is affected by Ethanol based on RNA-seq studies.
  • W08G11.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in germ line based on RNA-seq studies. Is affected by several genes including hpl-2; set-2; and lin-52 based on microarray and RNA-seq studies.
  • lin-48 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in anatomical structure morphogenesis and response to salt stress. Located in nucleus. Expressed in ciliated neurons; interfacial epithelial cell; intestine; labial sensillum; and tail. Human ortholog(s) of this gene implicated in posterior polymorphous corneal dystrophy 1. Is an ortholog of human OVOL1 (ovo like transcriptional repressor 1) and OVOL2 (ovo like zinc finger 2).
  • F54D1.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies. Is affected by glycine based on RNA-seq studies.
  • ekl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in protein secretion. Is an ortholog of human TANGO6 (transport and golgi organization 6 homolog).
  • par-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables protein kinase C binding activity and small GTPase binding activity. Involved in several processes, including establishment of mitotic spindle localization; gonad development; and polarity specification of anterior/posterior axis. Located in P granule and cell cortex. Is extrinsic component of cytoplasmic side of plasma membrane. Expressed in several structures, including ABa; EMS; Psub2; Psub3; and excretory cell. Is an ortholog of human PARD6B (par-6 family cell polarity regulator beta).
  • lin-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables beta-catenin binding activity and phosphatase binding activity. Involved in several processes, including negative regulation of centrosome duplication; regulation of protein stability; and ubiquitin-dependent protein catabolic process. Located in cytosol and nucleus. Part of cytoplasmic SCF ubiquitin ligase complex. Expressed in several structures, including body wall musculature; enteric muscle; germ line; hypodermal cell; and neurons. Is an ortholog of human FBXW11 (F-box and WD repeat domain containing 11).
  • ddx-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and RNA helicase activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleus. Is an ortholog of human DDX10 (DEAD-box helicase 10).
  • hst-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification and regulation of growth. Predicted to be located in membrane. Expressed in AIBL; AIBR; RIML; RIMR; and neurons. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome and hypogonadotropic hypogonadism 15 with or without anosmia. Is an ortholog of human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
  • cah-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Predicted to be located in cytoplasm. Expressed in head neurons; nervous system; and tail neurons. Is an ortholog of human CA6 (carbonic anhydrase 6).
  • C06E4.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including eat-2; lin-15B; and xpo-1 based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies.
  • C02F4.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including sir-2.1; clk-1; and lin-39 based on RNA-seq and microarray studies.
  • lin-39 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including positive regulation of DNA-templated transcription; positive regulation of developmental process; and regulation of cell division. Located in nucleus. Expressed in several structures, including hypodermis; male-specific anatomical entity; neurons; somatic nervous system; and ventral cord blast cell. Is an ortholog of human HOXA5 (homeobox A5).
  • lsy-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables mRNA 3'-UTR binding activity. Involved in determination of left/right asymmetry in nervous system and miRNA-mediated gene silencing. Expressed in ASEL; head neurons; and tail neurons.
  • F07C4.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in ABprpapppa; SIA; and g1P based on single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and clk-1 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including methylmercuric chloride; Mercuric Chloride; and Ag nanoparticles based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: ShKT domain and ShK domain-like.
  • T05B9.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-35; and lin-28 based on tiling array; RNA-seq; and microarray studies. Is affected by seven chemicals including metformin; Sirolimus; and Psoralens based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: PAN/Apple domain and PAN domain.
  • ccpp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables metallocarboxypeptidase activity. Involved in egg-laying behavior and proteolysis. Predicted to be located in cytoplasm. Is an ortholog of human AGBL4 (AGBL carboxypeptidase 4).
  • inx-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable gap junction hemi-channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Predicted to be located in gap junction and plasma membrane. Expressed in head neurons; pharyngeal cell; and rectal valve cell.
  • K06H6.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including eat-2; clk-1; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by Chlorpyrifos based on microarray studies.
  • Y50E8A.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ADE sheath cell; AVK; germline precursor cell; head mesodermal cell; and pm8 based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; daf-2; and dpy-10 based on microarray and RNA-seq studies. Is affected by fifteen chemicals including methylmercuric chloride; rotenone; and Tunicamycin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: THAP domain and THAP-type zinc finger.
  • mes-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in regulation of gene expression. Located in nucleus. Part of PcG protein complex and nucleosome. Expressed in several structures, including Caa; Psub4; Z2; Z3; and germ line.
  • aex-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable GTP binding activity and GTPase activity. Involved in exocytosis; positive regulation of defecation; and positive regulation of protein catabolic process. Located in synaptic vesicle. Expressed in ALML; ALMR; BDUL; BDUR; and neurons. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Is an ortholog of human RAB27A (RAB27A, member RAS oncogene family).
  • Y51A2A.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; eat-2; and hsp-6 based on microarray and RNA-seq studies.
  • 21ur-11897 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies.
  • B0564.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable dioxygenase activity. Predicted to be located in nucleus. Is an ortholog of human ALKBH6 (alkB homolog 6).
  • AC3.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-16; clk-1; and hsp-6 based on microarray and RNA-seq studies.
  • C31C9.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by isp-1 and nuo-6 based on microarray studies. Is affected by Sirolimus based on microarray studies.
  • C29F9.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-12; lin-15B; and mut-2 based on microarray and tiling array studies. Is affected by adsorbable organic bromine compound based on microarray studies.
  • clec-235 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by lin-15B; drh-3; and eat-2 based on microarray and RNA-seq studies. Is affected by Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.
  • sra-19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray studies. Is affected by resveratrol; adsorbable organic bromine compound; and Sirolimus based on microarray studies.
  • Y57G11C.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-12; lin-15B; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies.
  • F23F12.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; sir-2.1; and lin-35 based on RNA-seq and microarray studies. Is affected by Humic Substances and Sirolimus based on microarray studies.
  • ptps-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables 6-pyruvoyltetrahydropterin synthase activity and identical protein binding activity. Involved in tetrahydrobiopterin biosynthetic process. Predicted to be located in mitochondrion. Expressed in hypodermis and neurons. Human ortholog(s) of this gene implicated in BH4-deficient hyperphenylalaninemia A and phenylketonuria. Is an ortholog of human PTS (6-pyruvoyltetrahydropterin synthase).
  • lin-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. Located in cytoplasm; nucleus; and plasma membrane. Expressed in body wall musculature; neurons; vulva; and vulval precursor cell. Is an ortholog of human RYK (receptor like tyrosine kinase).
  • hsp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATP hydrolysis activity; heat shock protein binding activity; and protein folding chaperone. Involved in mitochondrial unfolded protein response. Located in mitochondrion. Expressed in muscle cell. Human ortholog(s) of this gene implicated in Alzheimer's disease; Parkinson's disease; autosomal dominant sideroblastic anemia 4; and rheumatoid arthritis. Is an ortholog of human HSPA9 (heat shock protein family A (Hsp70) member 9).
  • lin-44 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable cytokine activity and frizzled binding activity. Involved in several processes, including nematode male tail tip morphogenesis; neuron migration; and positive regulation of cell projection organization. Predicted to be located in extracellular space. Expressed in several structures, including P6.pa; P6.pp; anchor cell; rectal epithelial cell; and tail. Human ortholog(s) of this gene implicated in several diseases, including Schopf-Schulz-Passarge syndrome; carcinoma (multiple); and split hand-foot malformation 6. Is an ortholog of several human genes including WNT10B (Wnt family member 10B); WNT11 (Wnt family member 11); and WNT9B (Wnt family member 9B).
  • egl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable G protein-coupled peptide receptor activity. Involved in negative regulation of egg-laying behavior. Predicted to be located in plasma membrane. Expressed in GLR; nerve ring; and neurons.
  • aat-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables PDZ domain binding activity. Predicted to be involved in amino acid transmembrane transport. Located in apical plasma membrane.
  • gspd-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glucose-6-phosphate dehydrogenase activity. Predicted to be involved in glucose metabolic process and pentose-phosphate shunt, oxidative branch. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; diabetes mellitus (multiple); and favism. Is an ortholog of human G6PD (glucose-6-phosphate dehydrogenase).
  • R05A10.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; rrf-3; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by dafa#1 based on microarray studies.
  • F46A8.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including rrf-3; pgl-1; and lin-35 based on microarray and RNA-seq studies. Is affected by stavudine; allantoin; and Sirolimus based on RNA-seq studies.
  • F53E10.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including dpy-10; lin-35; and rde-4 based on microarray studies. Is affected by five chemicals including Humic Substances; R24; and paraquat based on microarray studies.
  • sup-39 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-12; etr-1; and rnp-6 based on tiling array and RNA-seq studies.
  • C41D11.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in membrane. Is an ortholog of human TM2D3 (TM2 domain containing 3).
  • srh-108 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on microarray studies. Is affected by etr-1; lpd-3; and lin-52 based on RNA-seq studies. Is affected by Sirolimus and allantoin based on microarray studies.
  • F29A7.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in maturation of 5.8S rRNA. Expressed widely. Is an ortholog of human MPHOSPH6 (M-phase phosphoprotein 6).
  • 21ur-13288 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD based on RNA-seq studies. Is affected by rnp-6 and cpl-1 based on RNA-seq studies.
  • C51F7.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD based on RNA-seq studies. Is affected by cep-1 and rnp-6 based on RNA-seq studies.
  • hpl-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables H3K27me3 modified histone binding activity and chromatin binding activity. Involved in several processes, including developmental process involved in reproduction; nematode larval development; and regulation of gene expression. Located in nuclear periphery. Expressed in several structures, including AWCL; AWCR; hyp7 syncytium; and vulval precursor cell.
  • ceph-41 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons and somatic gonad precursor based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including lin-4; lin-14; and sir-2.1 based on RNA-seq and microarray studies. Is affected by five chemicals including paraquat; Atrazine; and Colistin based on RNA-seq and microarray studies. Human ortholog(s) of this gene implicated in Joubert syndrome 15. Is an ortholog of human CEP41 (centrosomal protein 41).
  • scrm-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable phospholipid scramblase activity. Predicted to be involved in plasma membrane phospholipid scrambling. Predicted to be located in plasma membrane.
  • lin-33 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ABalaaaarl; accessory cell; excretory cell; head mesodermal cell; and neurons based on microarray; tiling array; RNA-seq; proteomic; and single-cell RNA-seq studies. Is affected by several genes including daf-2; let-7; and gld-1 based on microarray; RNA-seq; and proteomic studies. Is affected by eight chemicals including procyanidin; Sirolimus; and Rifampin based on microarray; RNA-seq; and proteomic studies. Is predicted to encode a protein with the following domain: Phosphorylation site.
  • cnc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in defense response to fungus and innate immune response. Expressed in intestine.
  • C51E3.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; lin-39; and adr-1 based on RNA-seq; tiling array; and microarray studies. Is affected by estrogen and Acrylamide based on microarray studies.
  • lin-30 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • lin-35 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of cell cycle; negative regulation of vulval development; and positive regulation of brood size. Located in nucleus. Expressed in several structures, including head and tail. Used to study intellectual disability. Human ortholog(s) of this gene implicated in several diseases, including germ cell cancer (multiple); high grade glioma (multiple); and urinary system cancer (multiple). Is an ortholog of human RBL1 (RB transcriptional corepressor like 1) and RBL2 (RB transcriptional corepressor like 2).
  • nduo-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable NADH dehydrogenase (ubiquinone) activity. Predicted to be located in mitochondrial membrane and respirasome.
  • T03F6.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glucosamine-6-phosphate deaminase activity and identical protein binding activity. Predicted to be involved in N-acetylglucosamine catabolic process; N-acetylneuraminate catabolic process; and glucosamine catabolic process. Predicted to be located in cytoplasm. Expressed in tail. Is an ortholog of human GNPDA1 (glucosamine-6-phosphate deaminase 1).
  • nsph-1.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including Caaaaa; Caaaap; anterior hypodermis; germ line; and mc1 based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including pgl-1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by four chemicals including rotenone; Rifampin; and paraquat based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Cytosolic motility protein.
  • CRE19958 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
  • Caenorhabditis remanei
    Is predicted to encode a protein with the following domains: Ras-mediated vulval-induction antagonist and Protein LIN-8. Is an ortholog of C. elegans lido-6.
  • clsp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable anaphase-promoting complex binding activity. Predicted to be involved in mitotic DNA replication checkpoint signaling and mitotic G2 DNA damage checkpoint signaling. Located in nucleus. Is an ortholog of human CLSPN (claspin).
  • acl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glycerol-3-phosphate O-acyltransferase activity. Predicted to be involved in cellular lipid metabolic process and glycerol-3-phosphate metabolic process. Located in mitochondrion. Expressed in muscle cell. Is an ortholog of human GPAM (glycerol-3-phosphate acyltransferase, mitochondrial).
  • fbxa-148 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including pgl-1; lin-15B; and fbf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride and Chlorpyrifos based on microarray studies.
  • F13H10.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in I band and striated muscle dense body. Is an ortholog of human ENPP6 (ectonucleotide pyrophosphatase/phosphodiesterase 6).
  • rme-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables small GTPase binding activity. Involved in endocytosis; molting cycle; and regulation of clathrin-dependent endocytosis. Located in clathrin-coated endocytic vesicle; early endosome; and plasma membrane. Expressed in several structures, including anterior gonad arm; coelomocyte; intestine; oocyte; and pharynx. Is an ortholog of human GAPVD1 (GTPase activating protein and VPS9 domains 1).
  • bus-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • T08G5.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including sir-2.1; nuo-6; and pptr-1 based on tiling array; RNA-seq; and microarray studies.
  • T28F2.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ABplapaaaap; ABplapaaap; ABprapaaaap; ABprapaaap; and intestine based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including sir-2.1; npr-1; and lin-35 based on quantitative PCR; microarray; and RNA-seq studies. Is affected by eight chemicals including rotenone; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: COMM domain-containing protein 4/6/7/8. Is an ortholog of human COMMD4 (COMM domain containing 4).
  • F58D5.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in sensory neurons based on RNA-seq studies. Is affected by nuo-6 and sek-1 based on RNA-seq studies.
  • mig-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable serine-type endopeptidase inhibitor activity. Involved in several processes, including anatomical structure morphogenesis; distal tip cell migration; and nematode larval development. Located in basement membrane. Expressed in several structures, including CAN; GLR; basal lamina; enteric muscle; and somatic gonad precursor. Is an ortholog of human PAPLN (papilin, proteoglycan like sulfated glycoprotein).
  • ain-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in several processes, including embryo development; negative regulation of gene expression; and regulation of developmental process. Located in P-body. Expressed widely.
  • sas-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in centriole replication. Located in centriole and cytoplasm.
  • csn-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable metallopeptidase activity. Predicted to be involved in oogenesis. Predicted to be located in cytoplasm and nucleus. Predicted to be part of COP9 signalosome. Is an ortholog of human COPS6 (COP9 signalosome subunit 6).
  • max-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • otpl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable proton channel activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in plasma membrane. Is an ortholog of human OTOP1 (otopetrin 1); OTOP2 (otopetrin 2); and OTOP3 (otopetrin 3).
  • CBN00007 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
  • Caenorhabditis brenneri
    Predicted to enable protein dimerization activity. Predicted to be involved in negative regulation of vulval development. Is an ortholog of C. elegans ZK662.5; ets-6; and lin-15B.
  • cct-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable unfolded protein binding activity. Predicted to be involved in protein folding. Predicted to be located in cytoplasm. Predicted to be part of chaperonin-containing T-complex. Is an ortholog of human CCT6B (chaperonin containing TCP1 subunit 6B).
  • osm-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in several processes, including non-motile cilium assembly; response to osmotic stress; and sensory perception of mechanical stimulus. Located in cilium; cytoplasm; and neuronal cell body. Expressed in neurons. Human ortholog(s) of this gene implicated in asphyxiating thoracic dystrophy. Is an ortholog of human IFT52 (intraflagellar transport 52).
  • gpi-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glucose-6-phosphate isomerase activity and monosaccharide binding activity. Predicted to be involved in gluconeogenesis; glucose 6-phosphate metabolic process; and glycolytic process. Predicted to be located in cytosol. Expressed in head. Used to study Parkinson's disease. Human ortholog(s) of this gene implicated in several diseases, including congenital nonspherocytic hemolytic anemia; leukemia (multiple); and neuromuscular disease. Is an ortholog of human GPI (glucose-6-phosphate isomerase).
  • pfk-1.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type); PFKM (phosphofructokinase, muscle); and PFKP (phosphofructokinase, platelet).
  • K05F6.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including eat-2; mir-35; and lin-54 based on RNA-seq and microarray studies. Is affected by five chemicals including resveratrol; Atrazine; and Quercetin based on microarray studies.
  • R03H10.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-35; alg-1; and hda-2 based on RNA-seq and microarray studies. Is affected by bortezomib; Sirolimus; and allantoin based on RNA-seq and microarray studies.
  • lpd-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable rRNA binding activity. Involved in lipid storage. Predicted to be located in membrane. Predicted to be part of preribosome, large subunit precursor. Is an ortholog of human PPAN (peter pan homolog) and PPAN-P2RY11 (PPAN-P2RY11 readthrough).
  • dyf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in intraciliary transport and non-motile cilium assembly. Located in dendrite and neuronal cell body. Expressed in ciliated neurons and hypodermis. Is an ortholog of human IFT46 (intraflagellar transport 46).
  • clec-124 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine and in male based on RNA-seq and microarray studies. Is affected by several genes including daf-2; lin-4; and lin-14 based on microarray and RNA-seq studies. Is affected by six chemicals including aldicarb; Zidovudine; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: C-type lectin fold; C-type lectin-like; and C-type lectin-like/link domain superfamily.
  • fbxa-68 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.
  • T28A11.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in body wall muscle cell based on tiling array studies. Is affected by several genes including sir-2.1; lin-35; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Thioredoxin-like fold; Thioredoxin-like superfamily; and Thioredoxin-like. Is an ortholog of human NXNL2 (nucleoredoxin like 2).
  • him-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables 3'-5' DNA helicase activity and enzyme binding activity. Involved in several processes, including determination of adult lifespan; meiotic nuclear division; and resolution of recombination intermediates. Located in chromosome and nucleus. Used to study Bloom syndrome. Human ortholog(s) of this gene implicated in Bloom syndrome. Is an ortholog of human BLM (BLM RecQ like helicase).
  • nol-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable RNA binding activity. Involved in negative regulation of innate immune response. Predicted to be located in condensed nuclear chromosome and nucleolus. Predicted to be part of CURI complex; UTP-C complex; and small-subunit processome. Is an ortholog of human NOL6 (nucleolar protein 6).
  • B0336.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA binding activity. Expressed in intestine and neurons.
  • F23F1.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ABalaaaarl; ABalaaaarr; accessory cell; anterior hypodermis; and rectal epithelium based on RNA-seq; single-cell RNA-seq; and microarray studies. Is affected by several genes including lin-4; eat-2; and lin-14 based on microarray and RNA-seq studies. Is affected by eight chemicals including Alovudine; stavudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: GM2-AP, lipid-recognition domain superfamily.
  • 21ur-4206 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by spt-16 and rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies.
  • 21ur-4710 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by spt-16 and rnp-6 based on RNA-seq studies. Is affected by D-glucose based on RNA-seq studies.
  • snf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables PDZ domain binding activity and acetylcholine transmembrane transporter activity. Involved in acetylcholine transport; choline transport; and positive regulation of locomotion. Predicted to be located in postsynaptic membrane. Expressed in body wall musculature; enteric muscle; neurons; and vulval muscle. Used to study Duchenne muscular dystrophy. Human ortholog(s) of this gene implicated in hyperekplexia 3 and obesity. Is an ortholog of human SLC6A14 (solute carrier family 6 member 14) and SLC6A5 (solute carrier family 6 member 5).
  • Y22F5A.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by set-6; baz-2; and egl-43 based on RNA-seq studies.
  • ZK617.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 and etr-1 based on RNA-seq studies. Is affected by Tunicamycin and Oligosaccharides based on microarray studies.
  • clec-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including skn-1; lin-4; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by twenty-three chemicals including aldicarb; tryptophan; and 1-methylnicotinamide based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Spermadhesin, CUB domain superfamily; C-type lectin-like; C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin fold; and CUB domain.
  • srz-36 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including lin-15B; hpl-2; and cyc-1 based on microarray and RNA-seq studies. Is affected by Rifampin; dibromoacetic acid; and nitroguanidine based on RNA-seq and microarray studies.
  • Y105C5A.1274 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on microarray studies. Is affected by several genes including sir-2.1; lin-35; and nhr-49 based on RNA-seq and microarray studies. Is affected by resveratrol based on microarray studies.
  • pals-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including skn-1; elt-2; and lin-35 based on microarray and RNA-seq studies. Is affected by seven chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.
  • him-17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in germline cell cycle switching, mitotic to meiotic cell cycle and resolution of meiotic recombination intermediates. Part of chromatin. Expressed in germ line; head; and tail.
  • Y53F4B.26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including pgl-1; dcr-1; and lin-15B based on microarray and RNA-seq studies. Is affected by five chemicals including allantoin; Sirolimus; and Psoralens based on RNA-seq studies.
  • F47B8.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Is an ortholog of human SLC37A4 (solute carrier family 37 member 4).
  • pfk-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable several functions, including 6-phosphofructokinase activity; carbohydrate derivative binding activity; and identical protein binding activity. Predicted to be involved in canonical glycolysis; fructose 1,6-bisphosphate metabolic process; and fructose 6-phosphate metabolic process. Predicted to be located in cytoplasm. Predicted to be part of 6-phosphofructokinase complex. Expressed in germ line; hypodermis; neurons; and pharynx. Human ortholog(s) of this gene implicated in glycogen storage disease VII. Is an ortholog of human PFKL (phosphofructokinase, liver type) and PFKM (phosphofructokinase, muscle).
  • sra-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Located in cilium. Expressed in head and tail.
  • fkb-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables Hsp90 protein binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in chaperone-mediated protein folding. Predicted to be located in cytoplasm. Expressed in dorsal nerve cord; intestine; and ventral nerve cord. Human ortholog(s) of this gene implicated in major depressive disorder. Is an ortholog of human FKBP4 (FKBP prolyl isomerase 4) and FKBP5 (FKBP prolyl isomerase 5).
  • daf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of dauer larval development; and regulation of insulin receptor signaling pathway. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including cuticle; excretory system; interfacial epithelial cell; neurons; and vulval cell. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)).
  • hcp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable histone binding activity. Involved in attachment of mitotic spindle microtubules to kinetochore; embryo development; and mitotic chromosome condensation. Located in condensed chromosome, centromeric region and nucleoplasm. Part of condensin complex. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Is an ortholog of human NCAPD3 (non-SMC condensin II complex subunit D3).
  • efa-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable guanyl-nucleotide exchange factor activity. Involved in several processes, including cellular component disassembly; regulation of cellular component organization; and regulation of mitotic centrosome separation. Located in cell cortex; microtubule minus-end; and plasma membrane. Expressed in U.la; U.lp; and linker cell. Is an ortholog of human PSD (pleckstrin and Sec7 domain containing).
  • lir-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA binding activity and metal ion binding activity. Predicted to be located in nucleus. Expressed in muscle cell; neurons; spermatheca; and vulva.
  • ccr-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable poly(A)-specific ribonuclease activity. Involved in nuclear-transcribed mRNA poly(A) tail shortening. Located in cytoplasm. Part of CCR4-NOT complex. Expressed in body wall musculature; germ line; neurons; somatic cell; and in male. Is an ortholog of human CNOT6 (CCR4-NOT transcription complex subunit 6) and CNOT6L (CCR4-NOT transcription complex subunit 6 like).
  • C53A5.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in cholinergic neurons and pharyngeal cell based on tiling array and single-cell RNA-seq studies. Is affected by several genes including skn-1; lin-4; and lin-14 based on microarray and RNA-seq studies. Is affected by ten chemicals including Tunicamycin; Psoralens; and allantoin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Galactose oxidase/kelch, beta-propeller; Kelch-type beta propeller; Kelch repeat type 1; and Kelch motif.
  • F46B3.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AVK; germline precursor cell; and hypodermis based on tiling array; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including lin-4; lin-14; and daf-3 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including tryptophan; Tunicamycin; and Rifampin based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: Protein of unknown function DUF282, Caenorhabditis species and Caenorhabditis protein of unknown function, DUF282.
  • elt-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in cell fate commitment; negative regulation of transcription by RNA polymerase II; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Expressed in several structures, including ABarpaapap; ABarpaappa; ABarpaappp; ABprpppppaa; and body wall muscle cell from MS lineage.
  • ubc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ubiquitin conjugating enzyme activity. Predicted to be involved in ubiquitin-dependent ERAD pathway. Predicted to be located in nucleus. Expressed in germ line and oocyte. Is an ortholog of human UBE2J1 (ubiquitin conjugating enzyme E2 J1).
  • srsx-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AWC-OFF based on single-cell RNA-seq studies. Is affected by lin-15B; adr-1; and etr-1 based on microarray and RNA-seq studies. Is affected by Sirolimus based on microarray studies.
  • twk-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Expressed in hypodermis and tail. Is an ortholog of several human genes including KCNK2 (potassium two pore domain channel subfamily K member 2); KCNK4 (potassium two pore domain channel subfamily K member 4); and KCNK5 (potassium two pore domain channel subfamily K member 5).
  • arf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable GTP binding activity and GTPase activity. Involved in negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; and positive regulation of endosome to plasma membrane protein transport. Located in basolateral plasma membrane; cytoplasmic side of apical plasma membrane; and recycling endosome membrane. Expressed in several structures, including excretory cell; intestine; pharyngeal muscle cell; ventral nerve cord; and vulva. Is an ortholog of human ARF6 (ADP ribosylation factor 6).
  • T04B8.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by unc-30; isp-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by paraquat based on microarray studies.
  • ZK1236.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by rnp-6 and etr-1 based on RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.
  • linc-85 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in PQR and somatic gonad precursor based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-2; cep-1; and lin-29 based on RNA-seq and microarray studies.
  • math-17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including skn-1; sir-2.1; and lin-35 based on microarray and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.
  • lir-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine; neurons; and somatic gonad precursor based on microarray and RNA-seq studies. Is affected by several genes including dpy-10; daf-12; and hsf-1 based on microarray; tiling array; and RNA-seq studies. Is affected by nine chemicals including Tunicamycin; stavudine; and metformin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Phosphorylation site.
  • linc-91 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including sek-1; cep-1; and lin-29 based on RNA-seq studies. Is affected by antimycin; atracurium; and paraquat based on RNA-seq studies.
  • E02H9.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by tdp-1; nhr-25; and nuo-6 based on microarray studies. Is affected by Atrazine; fluoranthene; and Microcystin-LR based on microarray studies.
  • tsp-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in common variable immunodeficiency 6. Is an ortholog of human CD81 (CD81 molecule).
  • blos-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in lysosome localization. Predicted to be part of BORC complex. Is an ortholog of human BORCS6 (BLOC-1 related complex subunit 6).
  • D1007.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in spliceosomal snRNP assembly. Located in striated muscle dense body. Is an ortholog of human GEMIN6 (gem nuclear organelle associated protein 6).
  • metl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable tRNA (cytosine-3-)-methyltransferase activity. Predicted to be involved in tRNA methylation. Is an ortholog of human METTL6 (methyltransferase 6, tRNA N3-cytidine).
  • Y53F4B.63 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by nuo-6 based on microarray studies. Is affected by six chemicals including Rifampin; Sirolimus; and allantoin based on RNA-seq and microarray studies.
  • evl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • clec-109 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including rrf-3; lin-4; and lin-14 based on tiling array; microarray; and RNA-seq studies. Is affected by four chemicals including Zidovudine; allantoin; and Sirolimus based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold and C-type lectin-like/link domain superfamily.
  • Y19D10B.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable metalloendopeptidase activity. Predicted to be involved in protein processing. Predicted to be located in plasma membrane.
  • rps-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytoplasm; nucleolus; and ribosome. Predicted to be part of small-subunit processome. Is an ortholog of human RPS6 (ribosomal protein S6).
  • Y102A5C.43 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including hsp-6; unc-30; and hpl-2 based on RNA-seq studies. Is affected by Colistin based on microarray studies.
  • srr-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD based on RNA-seq studies. Is affected by several genes including elt-2; lin-15B; and rrf-1 based on microarray and RNA-seq studies. Is affected by tryptophan and cadmium based on microarray studies.
  • rig-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable cell-cell adhesion mediator activity. Involved in several processes, including axon guidance; negative regulation of defecation rhythm; and regulation of locomotion. Located in axon; neuronal cell body; and synapse. Expressed in several structures, including body wall musculature; neurons; non-striated muscle; rectal epithelium; and spermatheca. Human ortholog(s) of this gene implicated in several diseases, including Compton-North congenital myopathy; familial adult myoclonic epilepsy 5; and high grade glioma. Is an ortholog of human CNTN6 (contactin 6).
  • mboa-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable 1-acylglycerophosphocholine O-acyltransferase activity and lysophospholipid acyltransferase activity. Involved in glycerophospholipid biosynthetic process; positive regulation of growth rate; and post-embryonic development. Predicted to be located in endoplasmic reticulum and membrane. Expressed in pharyngeal muscle cell and tail. Is an ortholog of human LPCAT3 (lysophosphatidylcholine acyltransferase 3).
  • mdt-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable transcription coactivator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED6 (mediator complex subunit 6).
  • PPA08494 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
  • Pristionchus pacificus
    Is predicted to encode a protein with the following domains: PDZ domain 6; PDZ domain; and PDZ superfamily. Is an ortholog of C. elegans lin-7. In C. elegans, lin-7 is involved in several processes, including egg-laying behavior; positive regulation of vulval development; and protein localization to basolateral plasma membrane.
  • C08E3.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including skn-1; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by seven chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq and microarray studies.
  • acr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable acetylcholine-gated monoatomic cation-selective channel activity. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Human ortholog(s) of this gene implicated in lung disease (multiple); nicotine dependence; and stomach cancer. Is an ortholog of human CHRNA3 (cholinergic receptor nicotinic alpha 3 subunit) and CHRNA6 (cholinergic receptor nicotinic alpha 6 subunit).
  • acp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic).
  • F54F7.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including hsp-6; mdt-15; and adr-1 based on RNA-seq studies. Is affected by Doxycycline based on RNA-seq studies.
  • grd-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Expressed in excretory duct and excretory pore. Is predicted to encode a protein with the following domain: Ground-like domain.
  • ser-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables octopamine receptor activity. Involved in positive regulation of fatty acid beta-oxidation by octopamine signaling pathway. Predicted to be located in dendrite. Expressed in intestine; neurons; and in male.
  • acp-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic).
  • acp-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to be located in membrane. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic).
  • linc-96 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including nhr-49; atfs-1; and nuo-6 based on RNA-seq studies. Is affected by Zidovudine based on RNA-seq studies.
  • cdc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATP binding activity and ATP hydrolysis activity. Predicted to be involved in mitotic DNA replication checkpoint signaling. Located in condensed nuclear chromosome; cytoplasm; and nucleolus. Expressed in seam cell. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 5. Is an ortholog of human CDC6 (cell division cycle 6).
  • gfat-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glutamine-fructose-6-phosphate transaminase (isomerizing) activity. Involved in IRE1-mediated unfolded protein response. Expressed in tail. Used to study Machado-Joseph disease. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 12; obesity; and type 2 diabetes mellitus. Is an ortholog of human GFPT1 (glutamine--fructose-6-phosphate transaminase 1).
  • C54G10.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; rrf-3; and lin-4 based on tiling array; microarray; and RNA-seq studies. Is affected by five chemicals including Tunicamycin; Sodium Chloride; and cholesterol based on microarray and RNA-seq studies.
  • D1005.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including nhr-49; lin-15B; and hpl-2 based on microarray and RNA-seq studies. Is affected by nine chemicals including hydrogen sulfide; methylmercuric chloride; and Mercuric Chloride based on microarray and RNA-seq studies.
  • fbxa-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in several structures, including ABalapapap; ABalapppap; ABalpapppa; ABarapappa; and AVK based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including age-1; lin-4; and eat-2 based on microarray and RNA-seq studies.
  • ceh-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in transdifferentiation. Acts upstream of with a positive effect on multicellular organismal-level water homeostasis. Located in cytosol and nucleus. Expressed in body wall musculature; hyp7 syncytium; intestine; and neurons. Human ortholog(s) of this gene implicated in X-linked deafness 2. Is an ortholog of human POU3F1 (POU class 3 homeobox 1); POU3F3 (POU class 3 homeobox 3); and POU3F4 (POU class 3 homeobox 4).
  • pgp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATPase-coupled transmembrane transporter activity and efflux transmembrane transporter activity. Involved in response to nematicide. Predicted to be located in plasma membrane. Expressed in amphid neurons and head. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); carcinoma (multiple); and intrahepatic cholestasis (multiple). Is an ortholog of several human genes including ABCB1 (ATP binding cassette subfamily B member 1); ABCB11 (ATP binding cassette subfamily B member 11); and ABCB4 (ATP binding cassette subfamily B member 4).
  • T24D5.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; sir-2.1; and lin-35 based on tiling array; RNA-seq; and microarray studies. Is affected by eleven chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies.
  • Y70C5B.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in somatic gonad precursor based on RNA-seq studies. Is affected by lin-15B and etr-1 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.
  • lin-66 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in negative regulation of gene expression and regulation of development, heterochronic. Located in cytoplasm. Expressed in body wall musculature; hypodermis; intestine; neurons; and vulval muscle.
  • sym-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Located in extracellular space. Expressed in vulB1 and vulB2.
  • dph-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable diphthine-ammonia ligase activity. Predicted to be involved in peptidyl-diphthamide biosynthetic process from peptidyl-histidine. Is an ortholog of human DPH6 (diphthamine biosynthesis 6).
  • lir-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Expressed in several structures, including head; intestinal cell; muscle cell; pharynx; and tail. Is predicted to encode a protein with the following domain: Phosphorylation site.
  • C25D7.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; dpy-10; and lin-4 based on RNA-seq and microarray studies. Is affected by nine chemicals including multi-walled carbon nanotube; Doxycycline; and Acrylamide based on RNA-seq and microarray studies.
  • F59H6.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD and head mesodermal cell based on RNA-seq studies. Is affected by several genes including daf-2; clk-1; and lin-35 based on microarray and RNA-seq studies. Is affected by Alovudine based on RNA-seq studies.
  • dnc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable dynein complex binding activity. Predicted to be involved in mitotic spindle organization. Part of dynactin complex. Is an ortholog of human DCTN6 (dynactin subunit 6).
  • F29C12.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-16; fbf-1; and nuo-6 based on RNA-seq and microarray studies. Is affected by Cry5B based on microarray studies.
  • F59B2.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable N-acetylglucosamine-6-phosphate deacetylase activity. Predicted to be involved in N-acetylglucosamine catabolic process. Is an ortholog of human AMDHD2 (amidohydrolase domain containing 2).
  • F13E9.20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by eat-2 and rnp-6 based on RNA-seq studies. Is affected by five chemicals including Zidovudine; Psoralens; and allantoin based on RNA-seq studies.
  • praf-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in membrane. Is an ortholog of human ARL6IP5 (ADP ribosylation factor like GTPase 6 interacting protein 5) and PRAF2 (PRA1 domain family member 2).
  • msh-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable four-way junction DNA binding activity and mismatched DNA binding activity. Involved in maintenance of DNA repeat elements and mismatch repair. Predicted to be located in nucleus. Predicted to be part of MutSalpha complex. Used to study Lynch syndrome. Human ortholog(s) of this gene implicated in several diseases, including colorectal carcinoma; hereditary nonpolyposis colorectal cancer type 5; and mismatch repair cancer syndrome. Is an ortholog of human MSH6 (mutS homolog 6).
  • elo-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable fatty acid elongase activity. Involved in methyl-branched fatty acid biosynthetic process. Predicted to be located in membrane. Expressed in amphid neurons; intestine; nerve ring; and vulva.
  • lin-59 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable histone H3K36 methyltransferase activity. Involved in several processes, including ectodermal cell fate specification; egg-laying behavior; and nematode male tail tip morphogenesis. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in hypodermis; intestine; and muscle cell. Used to study leukemia. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 52. Is an ortholog of human ASH1L (ASH1 like histone lysine methyltransferase).
  • hrg-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable heme binding activity and heme transmembrane transporter activity. Predicted to be involved in heme transport. Predicted to be located in lysosomal membrane and plasma membrane.
  • lsy-26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • puf-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable mRNA 3'-UTR binding activity. Involved in germ cell development. Predicted to be located in cytoplasm and nucleus.
  • C42C1.19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glucose 6-phosphate:inorganic phosphate antiporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II; glycogen storage disease Ib; and glycogen storage disease Ic. Is an ortholog of human SLC37A4 (solute carrier family 37 member 4).
  • D1081.19 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including isp-1; unc-30; and nuo-6 based on RNA-seq and microarray studies. Is affected by six chemicals including Atrazine; cadmium; and fluoranthene based on microarray studies. Is predicted to encode a protein with the following domains: Peptidase S1, PA clan; Nematode trypsin-6-like family; Chymotrypsin family Peptidase-S1; and Peptidase S1, PA clan, chymotrypsin-like fold.
  • lpr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in lipid transport. Predicted to be located in extracellular region. Expressed in amphid neurons.
  • lsy-20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • gst-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable glutathione transferase activity. Involved in innate immune response. Is an ortholog of human HPGDS (hematopoietic prostaglandin D synthase).
  • mfsd-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within with a positive effect on synaptic vesicle exocytosis. Located in synaptic vesicle. Is an ortholog of human MFSD6 (major facilitator superfamily domain containing 6).
  • ndx-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ADP-ribose diphosphatase activity and metal ion binding activity. Is an ortholog of human NUDT9 (nudix hydrolase 9).
  • prdx-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable peroxiredoxin activity. Predicted to be involved in cell redox homeostasis. Predicted to be located in cytosol and mitochondrion. Is an ortholog of human PRDX6 (peroxiredoxin 6).
  • mut-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • acp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable phosphatase activity. Predicted to be involved in dephosphorylation. Expressed in ALML; ALMR; PLML; PLMR; and spermatheca. Is an ortholog of human ACP6 (acid phosphatase 6, lysophosphatidic).
  • Y105C5B.1420 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; rrf-3; and hsp-6 based on microarray and RNA-seq studies. Is affected by antimycin based on RNA-seq studies.
  • E03H12.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in ALML; ALMR; BDUL; and BDUR based on single-cell RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on tiling array and microarray studies. Is affected by Sirolimus based on microarray studies.
  • C04E12.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-16; daf-12; and lin-4 based on tiling array; microarray; and RNA-seq studies. Is affected by twelve chemicals including multi-walled carbon nanotube; stavudine; and Psoralens based on RNA-seq and microarray studies.
  • Y38H8A.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including eat-2; lin-35; and aak-2 based on RNA-seq studies. Is affected by four chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies.
  • vha-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATPase binding activity. Involved in nematode larval development. Located in apical plasma membrane. Part of vacuolar proton-transporting V-type ATPase complex. Expressed in Psub2; excretory cell; hypodermis; pharyngeal-intestinal valve; and uterus. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive cutis laxa type IIA; autosomal recessive osteopetrosis 1; and developmental and epileptic encephalopathy 104. Is an ortholog of several human genes including ATP6V0A1 (ATPase H+ transporting V0 subunit a1); ATP6V0A2 (ATPase H+ transporting V0 subunit a2); and TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3).
  • linc-128 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons and sensory neurons based on RNA-seq studies. Is affected by several genes including unc-30; dlc-1; and efa-6 based on RNA-seq studies.
  • linc-53 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including nhr-49; cep-1; and rnp-6 based on RNA-seq studies. Is affected by stavudine and Zidovudine based on RNA-seq studies.
  • ric-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • B0511.12 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in endoplasmic reticulum organization. Predicted to be located in endoplasmic reticulum. Is an ortholog of human PCNX2 (pecanex 2) and PCNX3 (pecanex 3).
  • emb-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable mRNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Located in nucleus. Expressed in embryonic cell. Is an ortholog of human AQR (aquarius intron-binding spliceosomal factor).
  • xpo-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable tRNA binding activity. Predicted to be involved in tRNA re-export from nucleus. Predicted to be located in cytoplasm and nuclear matrix. Predicted to be part of nuclear pore. Is an ortholog of human XPOT (exportin for tRNA).
  • nhr-80 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Involved in determination of adult lifespan; positive regulation of metabolic process; and post-embryonic development. Located in nucleus. Expressed in head; intestine; muscle cell; somatic nervous system; and tail neurons.
  • Y52B11A.18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AVG based on single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-35 based on RNA-seq and microarray studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.
  • linc-31 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AVK and neurons based on RNA-seq studies. Is affected by several genes including etr-1; elli-1; and ints-6 based on microarray and RNA-seq studies.
  • rga-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in defense response to fungus. Used to study long QT syndrome. Is an ortholog of human ARHGAP36 (Rho GTPase activating protein 36) and ARHGAP6 (Rho GTPase activating protein 6).
  • fmil-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable calcium ion binding activity. Predicted to be located in membrane.
  • fut-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables galactoside 6-L-fucosyltransferase activity and glycoprotein 6-alpha-L-fucosyltransferase activity. Involved in fucosylation and protein N-linked glycosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT8 (fucosyltransferase 8).
  • srb-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable transmembrane signaling receptor activity. Involved in defense response to Gram-positive bacterium and detection of chemical stimulus. Located in cilium. Expressed in chemosensory neurons; head; tail; and uv1.
  • skr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable cullin family protein binding activity. Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to be located in cytoplasm and nucleus. Is an ortholog of human SKP1 (S-phase kinase associated protein 1).
  • wrt-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular space; and plasma membrane. Expressed in anterior ganglion (ant); hypodermis; and neuronal sheath cell. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human SHH (sonic hedgehog signaling molecule).
  • dop-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger; chemical synaptic transmission; and dopamine receptor signaling pathway. Predicted to be located in dendrite. Expressed in several structures, including AVF; SMDVL; head neurons; intestine; and lumbar neurons.
  • unc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable signaling receptor binding activity. Involved in several processes, including axon guidance; regulation of locomotion; and sex differentiation. Acts upstream of or within dendrite morphogenesis. Located in axon; basement membrane; and cytoplasm. Expressed in several structures, including P1; VA12; accessory cell; interneuron; and somatic neurons. Human ortholog(s) of this gene implicated in congenital mirror movement disorder. Is an ortholog of human NTN1 (netrin 1).
  • F09E10.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-16; daf-2; and lin-35 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; silicon dioxide nanoparticle; and Colistin based on RNA-seq and microarray studies.
  • lin-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in negative regulation of vulval development. Located in nucleus. Expressed in germ line; head neurons; and oocyte.
  • sma-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables BMP binding activity. Involved in several processes, including defense response to other organism; nematode male tail tip morphogenesis; and positive regulation of nitrogen compound metabolic process. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Expressed in ASI; hypodermis; intestinal cell; pharynx; and tail. Human ortholog(s) of this gene implicated in several diseases, including bone development disease (multiple); carcinoma (multiple); and glaucoma (multiple). Is an ortholog of human BMPR1B (bone morphogenetic protein receptor type 1B).
  • F35E2.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in male based on RNA-seq studies. Is affected by several genes including let-60; lin-4; and eat-2 based on RNA-seq and microarray studies. Is affected by seven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.
  • Y7A5A.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in muscle cell; neurons; and sensory neurons based on RNA-seq and microarray studies. Is affected by several genes including lin-22; hda-2; and etr-1 based on tiling array and RNA-seq studies. Is affected by fluoranthene based on microarray studies.
  • hsp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in germ line based on proteomic studies. Is affected by several genes including daf-16; lin-4; and eat-2 based on proteomic; microarray; and RNA-seq studies. Is affected by seven chemicals including metformin; allantoin; and Sirolimus based on RNA-seq studies.
  • Y45G12C.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including clk-1; lin-15B; and cyc-1 based on microarray and RNA-seq studies. Is predicted to encode a protein with the following domains: 7TM GPCR, serpentine receptor class r (Str) and Serpentine type 7TM GPCR chemoreceptor Str.
  • nspf-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-39 based on RNA-seq; tiling array; and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.
  • R106.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in DD neuron and neurons based on microarray studies. Is affected by several genes including dpy-10; eat-2; and lin-35 based on RNA-seq and microarray studies. Is affected by four chemicals including Quercetin; Hydrolyzable Tannins; and Sirolimus based on microarray studies.
  • cat-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Acts upstream of or within non-motile cilium assembly.
  • W02D9.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in trans-Golgi network. Is an ortholog of human YIPF6 (Yip1 domain family member 6).
  • arp-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable nucleosome binding activity. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of Swr1 complex. Is an ortholog of human ACTR6 (actin related protein 6).
  • B0507.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including sir-2.1; lin-15B; and prg-1 based on microarray; tiling array; and RNA-seq studies. Is affected by aldicarb; Rifampin; and bortezomib based on microarray and RNA-seq studies.
  • met-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables histone H3K36 methyltransferase activity. Involved in negative regulation of transcription by RNA polymerase II and negative regulation of vulval development. Predicted to be located in nucleus. Predicted to be part of chromatin. Expressed in hypodermis; intestine; and muscle cell. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and idiopathic pulmonary fibrosis. Is an ortholog of human SETD2 (SET domain containing 2, histone lysine methyltransferase).
  • gly-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein glycosylation. Predicted to be located in Golgi apparatus. Is an ortholog of human GALNTL6 (polypeptide N-acetylgalactosaminyltransferase like 6).
  • Cjp-lin-36 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
  • Caenorhabditis japonica
    Is an ortholog of C. elegans lin-36. In C. elegans, lin-36 is involved in embryonic digestive tract morphogenesis.
  • F22E5.22 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including pmk-1; tax-6; and ogt-1 based on microarray studies. Is affected by four chemicals including Testosterone; Colistin; and dafa#1 based on microarray studies.
  • pde-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable 3',5'-cyclic-AMP phosphodiesterase activity. Involved in negative regulation of oocyte maturation. Human ortholog(s) of this gene implicated in primary pigmented nodular adrenocortical disease. Is an ortholog of human PDE8A (phosphodiesterase 8A) and PDE8B (phosphodiesterase 8B).
  • sup-17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable metalloendopeptidase activity. Involved in several processes, including nematode male tail tip morphogenesis; positive regulation of transforming growth factor beta receptor signaling pathway; and vulval development. Located in cytoplasmic vesicle membrane and plasma membrane. Expressed in M lineage cell; hypodermis; intestinal cell; spermatheca; and vulva. Human ortholog(s) of this gene implicated in Alzheimer's disease 18; colorectal cancer; and reticulate acropigmentation of Kitamura. Is an ortholog of human ADAM10 (ADAM metallopeptidase domain 10).
  • fat-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables stearoyl-CoA 9-desaturase activity. Involved in innate immune response; long-chain fatty acid biosynthetic process; and post-embryonic development. Predicted to be located in endoplasmic reticulum membrane. Expressed in hypodermis. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 79. Is an ortholog of human SCD (stearoyl-CoA desaturase) and SCD5 (stearoyl-CoA desaturase 5).
  • elo-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable fatty acid elongase activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in membrane.
  • stu-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
  • T03G6.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Located in I band and striated muscle dense body. Expressed in vulval muscle. Is an ortholog of human ENPP6 (ectonucleotide pyrophosphatase/phosphodiesterase 6).
  • lin-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables small GTPase binding activity. Involved in several processes, including neuron-neuron synaptic transmission; positive regulation of backward locomotion; and protein localization. Located in several cellular components, including Golgi trans cisterna; somatodendritic compartment; and trans-Golgi network transport vesicle. Expressed in several structures, including ganglia; somatic gonad precursor; somatic nervous system; vulva; and vulval precursor cell. Is an ortholog of human APBA1 (amyloid beta precursor protein binding family A member 1) and APBA2 (amyloid beta precursor protein binding family A member 2).
  • mes-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables histone H3K27 methyltransferase activity. Involved in epigenetic regulation of gene expression; germ-line stem cell division; and tissue development. Part of PcG protein complex and nucleosome. Expressed in Z2; Z3; germ line; hypodermis; and intestine. Human ortholog(s) of this gene implicated in several diseases, including gastrointestinal system cancer (multiple); hematologic cancer (multiple); and respiratory system cancer (multiple). Is an ortholog of human EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit) and EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit).
  • pas-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in proteasomal protein catabolic process. Predicted to be located in nucleus. Predicted to be part of proteasome core complex, alpha-subunit complex. Is an ortholog of human PSMA1 (proteasome 20S subunit alpha 1).
  • nhr-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II; regulation of ovulation; and spermathecum morphogenesis. Located in nucleus. Expressed in BAGL; BAGR; chemosensory neurons; head neurons; and spermatheca. Human ortholog(s) of this gene implicated in Parkinson's disease and extraskeletal myxoid chondrosarcoma. Is an ortholog of human NR4A2 (nuclear receptor subfamily 4 group A member 2) and NR4A3 (nuclear receptor subfamily 4 group A member 3).
  • epg-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables phosphatidylinositol phosphate binding activity. Involved in autophagosome assembly. Located in cytoplasm. Expressed widely. Human ortholog(s) of this gene implicated in neurodegeneration with brain iron accumulation 5. Is an ortholog of human WDR45 (WD repeat domain 45).
  • Y65B4A.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine based on RNA-seq studies. Is affected by several genes including eat-2; pgl-1; and lin-15B based on microarray and RNA-seq studies. Is affected by eight chemicals including D-glucopyranose; Psoralens; and allantoin based on RNA-seq and microarray studies.
  • F40C5.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-16; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by five chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies.
  • Y37H2A.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including eat-2; lin-35; and nhr-49 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including aldicarb; hydrogen sulfide; and methylmercuric chloride based on microarray studies.
  • Cbn-lin-38 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
  • Caenorhabditis brenneri
    Is an ortholog of C. elegans lin-38. In C. elegans, lin-38 is involved in negative regulation of vulval development.
  • Cbr-lin-11 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
  • Caenorhabditis briggsae
    Predicted to enable DNA binding activity. Is an ortholog of C. elegans lin-11. In C. elegans, lin-11 is involved in several processes, including axonal fasciculation; egg-laying behavior; and positive regulation of vulval development.
  • orc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable ATP binding activity; ATP hydrolysis activity; and DNA binding activity. Predicted to be involved in DNA replication initiation and mitotic DNA replication checkpoint signaling. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 1. Is an ortholog of human ORC1 (origin recognition complex subunit 1).
  • K08E5.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AIBL and AIBR based on single-cell RNA-seq studies. Is affected by several genes including daf-16; lin-35; and cep-1 based on RNA-seq and microarray studies. Is affected by seven chemicals including rotenone; stavudine; and allantoin based on RNA-seq studies.
  • R02D5.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in intestine and in male based on RNA-seq studies. Is affected by several genes including rrf-3; pgl-1; and lin-29 based on RNA-seq studies. Is affected by five chemicals including antimycin; Cry5B; and cholesterol based on RNA-seq and microarray studies.
  • T26E4.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in g1AL; g1AR; and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including sir-2.1; lin-15B; and cyc-1 based on microarray; tiling array; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies.
  • Y116A8C.43 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-15B based on microarray and RNA-seq studies. Is affected by four chemicals including multi-walled carbon nanotube; Sirolimus; and Rifampin based on RNA-seq studies.
  • Cbr-lin-38 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
  • Caenorhabditis briggsae
    Is an ortholog of C. elegans lin-38. In C. elegans, lin-38 is involved in negative regulation of vulval development.
  • Ppa-lin-38.2 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
  • Pristionchus pacificus
    Is an ortholog of C. elegans lin-38. In C. elegans, lin-38 is involved in negative regulation of vulval development.
  • Cre-lin-38 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
  • Caenorhabditis remanei
    Is an ortholog of C. elegans lin-38. In C. elegans, lin-38 is involved in negative regulation of vulval development.
  • F38A1.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in MC neuron; MCL; MCR; and intestine based on single-cell RNA-seq and microarray studies. Is affected by several genes including daf-2; clk-1; and lin-15B based on microarray; tiling array; and RNA-seq studies. Is affected by resveratrol based on microarray studies.
  • F44F1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on RNA-seq and microarray studies. Is affected by four chemicals including methylmercuric chloride; cholesterol; and Doxycycline based on microarray and RNA-seq studies.
  • F42A9.18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in BAG and neurons based on single-cell RNA-seq and RNA-seq studies. Is affected by several genes including isp-1; nuo-6; and spc-1 based on RNA-seq studies.
  • F56B3.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Is an ortholog of human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6).
  • K08H10.5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including daf-2; eat-2; and hsp-6 based on RNA-seq and microarray studies. Is affected by methylmercury hydroxide; Doxycycline; and paraquat based on RNA-seq studies.
  • fut-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity. Involved in fucosylation. Predicted to be located in Golgi cisterna membrane. Is an ortholog of human FUT5 (fucosyltransferase 5) and FUT6 (fucosyltransferase 6).
  • hxk-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable fructokinase activity and glucokinase activity. Predicted to be involved in carbohydrate metabolic process; glucose 6-phosphate metabolic process; and intracellular glucose homeostasis. Predicted to be located in cytosol and mitochondrion.
  • T03F6.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be located in membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa 77. Is an ortholog of human REEP5 (receptor accessory protein 5) and REEP6 (receptor accessory protein 6).
  • Y116A8A.150 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including dlc-1; etr-1; and set-6 based on RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and metformin based on RNA-seq studies.
  • K02F2.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD; AVK; intestine; and somatic gonad precursor based on RNA-seq studies. Is affected by several genes including eat-2; hsp-6; and crh-1 based on RNA-seq and microarray studies.
  • linc-72 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including hsf-1; cep-1; and hsp-6 based on RNA-seq studies. Is affected by four chemicals including D-glucopyranose; Alovudine; and stavudine based on RNA-seq studies.
  • emc-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to be involved in autophagosome assembly. Predicted to be located in endoplasmic reticulum membrane. Predicted to be part of EMC complex. Is an ortholog of human EMC6 (ER membrane protein complex subunit 6).
  • F08F8.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Is affected by several genes including sir-2.1; nuo-6; and mrps-5 based on RNA-seq and microarray studies. Is affected by Diazinon; paraquat; and adsorbable organic bromine compound based on microarray studies.
  • F15H10.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in dopaminergic neurons based on tiling array studies. Is affected by several genes including eat-2; sir-2.1; and lin-35 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies.
  • K12B6.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in germ line based on RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray; RNA-seq; and proteomic studies. Is affected by seven chemicals including D-glucose; bisphenol A; and stavudine based on RNA-seq and microarray studies.
  • srlf-34 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Involved in response to gamma radiation.
  • C24H10.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in hypodermis based on RNA-seq studies. Is affected by several genes including clk-1; lin-35; and mex-1 based on microarray; tiling array; and RNA-seq studies. Is affected by four chemicals including hydrogen sulfide; Doxycycline; and dafa#1 based on microarray and RNA-seq studies.
  • fbxa-58 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AVA and intestine based on tiling array and microarray studies. Is affected by several genes including daf-16; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by paraquat; allantoin; and silicon dioxide nanoparticle based on microarray and RNA-seq studies.
  • T08G3.7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; lin-4; and eat-2 based on microarray; tiling array; and RNA-seq studies. Is affected by ten chemicals including methylmercuric chloride; Tunicamycin; and manganese chloride based on microarray and RNA-seq studies.
  • Y60C6A.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in RIC based on single-cell RNA-seq studies. Is affected by several genes including skn-1; sir-2.1; and lin-35 based on RNA-seq and microarray studies. Is affected by thirteen chemicals including stearic acid; sucrose; and Cry5B based on RNA-seq and microarray studies.
  • C04C3.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in FLPL and FLPR based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and lin-35 based on microarray and RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq and microarray studies.
  • C50H11.17 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in amphid sheath cell based on RNA-seq studies. Is affected by several genes including nhr-49; lin-15B; and hpl-2 based on microarray; tiling array; and RNA-seq studies. Is affected by tryptophan; multi-walled carbon nanotube; and Sirolimus based on microarray and RNA-seq studies.
  • F37C12.14 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in germ line and neurons based on microarray; RNA-seq; and single-cell RNA-seq studies. Is affected by several genes including daf-2; eat-2; and lin-35 based on microarray and RNA-seq studies. Is affected by multi-walled carbon nanotube based on RNA-seq studies.
  • F40H6.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in AFD; RID; neurons; posterior arcade cell; and in male based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including sir-2.1; lin-35; and alg-1 based on RNA-seq and microarray studies. Is affected by fluoranthene based on microarray studies.
  • K10H10.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enriched in NSM and neurons based on tiling array and RNA-seq studies. Is affected by several genes including eat-2; lin-15B; and set-2 based on microarray and RNA-seq studies. Is affected by five chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.
  • mstr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable DNA binding activity and zinc ion binding activity. Located in nucleus. Is an ortholog of human ZFAND5 (zinc finger AN1-type containing 5) and ZFAND6 (zinc finger AN1-type containing 6).
  • Cjp-lin-65 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
  • Caenorhabditis japonica
    Is an ortholog of C. elegans lin-65. In C. elegans, lin-65 is involved in chromatin remodeling and mitochondrial unfolded protein response.
  • Cbn-lin-65.1 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
  • Caenorhabditis brenneri
    Is an ortholog of C. elegans lin-65. In C. elegans, lin-65 is involved in chromatin remodeling and mitochondrial unfolded protein response.
  • Cre-lin-65 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
  • Caenorhabditis remanei
    Is an ortholog of C. elegans lin-65. In C. elegans, lin-65 is involved in chromatin remodeling and mitochondrial unfolded protein response.
  • cids-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD1A (regulation of nuclear pre-mRNA domain containing 1A).
  • cids-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable RNA polymerase II complex binding activity. Involved in mRNA 3'-end processing. Is an ortholog of human RPRD2 (regulation of nuclear pre-mRNA domain containing 2).
  • met-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables histone H3K36 methyltransferase activity and histone H3K9 methyltransferase activity. Involved in several processes, including negative regulation of vulval development; regulation of gene expression; and vulval cell fate commitment. Located in cytoplasm. Expressed in hypodermis; intestine; muscle cell; neurons; and in male. Human ortholog(s) of this gene implicated in several diseases, including Huntington's disease; autistic disorder; and prostate cancer. Is an ortholog of human SETDB1 (SET domain bifurcated histone lysine methyltransferase 1).
  • ctsa-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Predicted to enable serine-type carboxypeptidase activity. Predicted to be involved in proteolysis. Expressed in gonad. Human ortholog(s) of this gene implicated in galactosialidosis. Is an ortholog of human CTSA (cathepsin A).
  • grl-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Expressed in PVT. Is predicted to encode a protein with the following domain: Ground-like domain.
  • sel-7 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
  • Caenorhabditis elegans
    Enables identical protein binding activity and sequence-specific DNA binding activity. Involved in several processes, including lateral inhibition; negative regulation of transcription by RNA polymerase II; and positive regulation of Notch signaling pathway. Located in nucleus. Expressed in body wall musculature; pharyngeal muscle cell; and seam cell.
  • Cjp-lin-33 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
  • Caenorhabditis japonica
    Is an ortholog of C. elegans lin-33.
  • Cbn-lin-65.2 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
  • Caenorhabditis brenneri
    Is an ortholog of C. elegans lin-65. In C. elegans, lin-65 is involved in chromatin remodeling and mitochondrial unfolded protein response.
  • Cbr-lin-65 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
  • Caenorhabditis briggsae
    Is an ortholog of C. elegans lin-65. In C. elegans, lin-65 is involved in chromatin remodeling and mitochondrial unfolded protein response.
  • Bma-lin-33 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
  • Brugia malayi
    Is an ortholog of C. elegans lin-33.