vab-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; negative regulation of distal tip cell migration; and positive regulation of glial cell differentiation. Located in cytoplasm and nucleus. Expressed in several structures, including Y.p; distal tip cell; head muscle; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including bilateral optic nerve hypoplasia; eye disease (multiple); and glucose intolerance. Is an ortholog of human PAX6 (paired box 6).
mab-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ADF; SMD; and in male.
scl-21 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be located in extracellular space. Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain family 18 member B); and CLEC18C (C-type lectin domain family 18 member C).
mab-21 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis. Expressed in several structures, including PVC; VA2;
hyp7 syncytium; ray 6; and sensory neurons. Human ortholog(s) of this gene implicated in coloboma and syndromic microphthalmia 14. Is an ortholog of human MAB21L1 (
mab-21 like 1) and MAB21L2 (
mab-21 like 2).
mab-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metal ion binding activity and sequence-specific DNA binding activity. Involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. Located in nucleus. Expressed in several structures, including U cell; hermaphrodite gonad; neurons; tail hypodermis; and ventral nerve cord.
ins-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in maintenance of dauer; negative regulation of insulin receptor signaling pathway; and regulation of dauer entry. Expressed in several structures, including coelomocyte; gonad; head muscle; nerve ring; and neurons.
mec-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable CoA-ligase activity. Involved in detection of mechanical stimulus involved in sensory perception of touch and mechanosensory behavior. Located in neuron projection and neuronal cell body. Expressed in PLML; PLMR; and touch receptor neurons.
glb-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Located in endoplasmic reticulum. Expressed in ventral nerve cord.
gcy-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in microvillus membrane and neuron projection terminus. Expressed in intestine and nervous system.
twk-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables outward rectifier potassium channel activity. Involved in locomotion; muscle contraction; and potassium ion transport. Predicted to be located in membrane. Expressed in body wall musculature.
mab-20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables semaphorin receptor binding activity. Involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. Located in cell surface. Expressed in several structures, including linker cell; ray neurons; ray precursor cell; somatic nervous system; and vulval cell. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of human SEMA3B (semaphorin 3B) and SEMA3C (semaphorin 3C).
ubc-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in determination of adult lifespan; embryonic digestive tract morphogenesis; and protein metabolic process. Acts upstream of or within animal organ morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5).
klp-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic spindle assembly. Located in cell cortex; microtubule; and spindle pole. Expressed in Z2; Z3; and germ line. Is an ortholog of human KIF15 (kinesin family member 15).
vha-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Is an ortholog of human ATP6V1H (ATPase H+ transporting V1 subunit H).
dpy-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables procollagen-proline 4-dioxygenase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; embryo development; and embryonic body morphogenesis. Located in endoplasmic reticulum. Expressed in hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in myopia. Is an ortholog of human P4HA1 (prolyl 4-hydroxylase subunit alpha 1) and P4HA2 (prolyl 4-hydroxylase subunit alpha 2).
unc-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables syntaxin binding activity. Involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. Located in axon. Expressed in head neurons; intestine; nervous system;
uv1; and ventral cord neurons. Used to study alcohol use disorder and developmental and epileptic encephalopathy. Human ortholog(s) of this gene implicated in West syndrome; developmental and epileptic encephalopathy 4; and familial hemophagocytic lymphohistiocytosis 5. Is an ortholog of human STXBP1 (syntaxin binding protein 1).
his-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9).
mab-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including body ganglion; body wall musculature; male-specific anatomical entity; neurons; and vulval cell. Is an ortholog of human HOXB8 (homeobox B8) and HOXC8 (homeobox C8).
vps-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein-macromolecule adaptor activity. Involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. Located in cytoplasm. Expressed in body wall musculature; coelomocyte; hermaphrodite gonad; hypodermis; and intestine. Is an ortholog of human VPS18 (VPS18 core subunit of CORVET and HOPS complexes).
rpl-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Is an ortholog of human RPL18 (ribosomal protein L18).
flp-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable neuropeptide Y receptor binding activity. Involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. Predicted to be located in extracellular space. Expressed in coelomocyte; head; neurons; tail; and in male.
bus-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables acyltransferase activity. Involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. Located in endoplasmic reticulum. Expressed in several structures, including AIY; excretory gland cell; hypodermis; interfacial epithelial cell; and vulva. Is an ortholog of human LCLAT1 (lysocardiolipin acyltransferase 1).
vpat-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC18B1 (solute carrier family 18 member B1).
drag-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable coreceptor activity. Involved in several processes, including mesodermal cell fate specification; regulation of BMP signaling pathway; and regulation of dauer larval development. Located in plasma membrane. Part of receptor complex. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in hemochromatosis type 2A and multiple sclerosis. Is an ortholog of human HJV (hemojuvelin BMP co-receptor) and RGMA (repulsive guidance molecule BMP co-receptor a).
mab-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and post-embryonic hindgut morphogenesis. Located in nucleus. Expressed in several structures, including B.a; B.p; neurons; proctodeum; and rectal epithelial cell. Human ortholog(s) of this gene implicated in atrial heart septal defect 4; tetralogy of Fallot; and ventricular septal defect. Is an ortholog of human TBX20 (T-box transcription factor 20).
C53B4.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in nucleus. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple) and breast cancer. Is an ortholog of human SLC22A18 (solute carrier family 22 member 18).
atg-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables phosphatidylinositol phosphate binding activity. Involved in several processes, including determination of adult lifespan; gamete generation; and xenophagy. Acts upstream of or within with a positive effect on plasma membrane repair. Located in phagocytic vesicle. Expressed in several structures, including head and tail. Used to study Huntington's disease. Is an ortholog of human WIPI2 (WD repeat domain, phosphoinositide interacting 2).
C16C10.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human SAP18 (Sin3A associated protein 18).
SRAE_2000017800 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
Cbr-mab-21 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
Ovo-mab-21 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
Ppa-mab-21 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
Cre-mab-21 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
TMUE_2000010211 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
Cbn-mab-21 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
Cjp-mab-21 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Neurobeachin-like, DUF1088; Mab-21 domain; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
syx-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum. Predicted to be part of SNARE complex. Is an ortholog of human STX18 (syntaxin 18).
rab-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and lipid droplet organization. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Is an ortholog of human RAB18 (RAB18, member RAS oncogene family).
ceh-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; gamete generation; and negative regulation of oocyte maturation. Located in nucleus. Expressed in body wall musculature; gonad; neurons; non-striated muscle; and somatic nervous system. Is an ortholog of human POU2F2 (POU class 2 homeobox 2) and POU2F3 (POU class 2 homeobox 3).
gcy-23 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in neuron projection terminus. Expressed in AFDL and AFDR.
plx-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables semaphorin receptor activity. Involved in several processes, including axonal fasciculation; nematode larval development; and nematode male tail tip morphogenesis. Located in cell leading edge and cell surface. Expressed in several structures, including P3/4L; P9/10L; P9/10R; neuroblasts; and ray structural cell.
Bma-mab-21 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans
mab-21. In C. elegans,
mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis.
nuaf-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 18. Is an ortholog of human NDUFAF3 (NADH:ubiquinone oxidoreductase complex assembly factor 3).
slc-25A21 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 18. Is an ortholog of human SLC25A21 (solute carrier family 25 member 21).
set-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables histone H3K36 methyltransferase activity. Predicted to be involved in chromatin remodeling. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in body wall musculature; non-striated muscle; pharynx; and vulva. Is an ortholog of human SMYD1 (SET and MYND domain containing 1) and SMYD3 (SET and MYND domain containing 3).
znf-593 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable metal ion binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in cytoplasm and nucleus. Expressed in head. Is an ortholog of human ZNF593 (zinc finger protein 593).
lin-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. Located in cytoplasm; nucleus; and plasma membrane. Expressed in body wall musculature; neurons; vulva; and vulval precursor cell. Is an ortholog of human RYK (receptor like tyrosine kinase).
C04F12.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. Located in striated muscle myosin thick filament. Is an ortholog of human DUSP14 (dual specificity phosphatase 14); DUSP18 (dual specificity phosphatase 18); and DUSP21 (dual specificity phosphatase 21).
ptr-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in apical plasma membrane. Expressed in hypodermal cell; seam cell; and ventral cord blast cell.
ndx-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 8-oxo-GDP phosphatase activity; 8-oxo-dGDP phosphatase activity; and magnesium ion binding activity. Located in sarcoplasmic reticulum. Expressed in spermatheca and vulval muscle. Is an ortholog of human NUDT18 (nudix hydrolase 18).
Ppa-mab-5 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
nhr-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in anal depressor muscle; intestinal muscle; and vulval muscle.
gcy-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR.
npr-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Involved in regulation of muscle contraction. Predicted to be located in neuron projection and plasma membrane. Expressed in body wall musculature; chemosensory neurons; and head neurons. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor).
K07C11.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in receptor localization to non-motile cilium. Predicted to be part of BBSome. Expressed in amphid neurons and phasmid neurons. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 18. Is an ortholog of human BBIP1 (BBSome interacting protein 1).
Mab21l4 [Search on AGR]
Rattus norvegicus Orthologous to human MAB21L4 (
mab-21 like 4); INTERACTS WITH acetamide; bisphenol A; Cuprizon.
prp-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa 18. Is an ortholog of human PRPF3 (pre-mRNA processing factor 3).
wdfy-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be located in cytosol and membrane. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Is an ortholog of human WDFY3 (WD repeat and FYVE domain containing 3).
tctn-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in cilium assembly. Predicted to be located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital syndrome IV. Is an ortholog of human TCTN1 (tectonic family member 1) and TCTN3 (tectonic family member 3).
ttm-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. Is an ortholog of human DEGS1 (delta 4-desaturase, sphingolipid 1) and DEGS2 (delta 4-desaturase, sphingolipid 2).
ZC262.10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
daf-18;
csr-1; and
nhr-8 based on RNA-seq and microarray studies. Is affected by methylmercury hydroxide based on RNA-seq studies. Is predicted to encode a protein with the following domains: Tight junction protein, Claudin-like and Tight junction protein, claudin-like.
F33D4.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. Is an ortholog of human DEGS1 (delta 4-desaturase, sphingolipid 1) and DEGS2 (delta 4-desaturase, sphingolipid 2).
prp-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be involved in generation of catalytic spliceosome for second transesterification step. Predicted to be located in nuclear speck. Predicted to be part of U2-type post-spliceosomal complex; U4/U6 x U5 tri-snRNP complex; and U5 snRNP. Is an ortholog of human PRPF18 (pre-mRNA processing factor 18).
F41C6.6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in ABplpppaaa and ABprpppaaa based on single-cell RNA-seq studies. Is affected by several genes including
daf-16;
nhr-49; and
daf-18 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies.
rps-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of small ribosomal subunit. Is an ortholog of human RPS18 (ribosomal protein S18).
mdt-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II and termination of RNA polymerase II transcription. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED18 (mediator complex subunit 18).
Bma-mab-5 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
Cjp-mab-5 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
acr-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in neurons and ray.
Mb21d2 [Search on AGR]
Rattus norvegicus Orthologous to human MB21D2 (Mab-21 domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride.
CBG00043 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
Cbn-mab-5 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
Cre-mab-5 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
Cbr-mab-5 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
Ovo-mab-5 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
SRAE_1000326000 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Predicted to enable DNA binding activity. Is an ortholog of C. elegans
mab-5. In C. elegans,
mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.
alh-13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable glutamate-5-semialdehyde dehydrogenase activity. Predicted to be involved in L-proline biosynthetic process and phosphorylation. Located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including cutis laxa (multiple); enterocele; and hereditary spastic paraplegia (multiple). Is an ortholog of human ALDH18A1 (aldehyde dehydrogenase 18 family member A1).
C45G9.8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in AIB and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including
eat-2;
daf-18; and
csr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies.
Y52B11A.11 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in ABplpppppp; ABprpppppp; AVG; RIM; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including
daf-16;
hsf-1; and
daf-18 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies.
SZT2-AS1 [Search on AGR]
Homo sapiens ASSOCIATED WITH developmental and epileptic encephalopathy 18; genetic disease; Obesity
Mab21l3 [Search on AGR]
Rattus norvegicus Orthologous to human MAB21L3 (
mab-21 like 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl.
twk-48 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in migraine. Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18).
Y46C8AM.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
daf-16;
skn-1; and
daf-18 based on RNA-seq and microarray studies. Is affected by nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin-like/link domain superfamily; Lectin C-type domain; C-type lectin-like; and C-type lectin fold.
F41G3.20 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
daf-2;
daf-18; and
isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including resveratrol; Hydrolyzable Tannins; and Humic Substances based on microarray studies. Is predicted to encode a protein with the following domains: ShK domain-like; CC domain; and ShKT domain.
twk-39 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in migraine. Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18).
OVOC6127 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans
mab-23. In C. elegans,
mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process.
Ppa-mab-23 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans
mab-23. In C. elegans,
mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process.
cat-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables dopamine:sodium symporter activity and serotonin:sodium:chloride symporter activity. Involved in dopamine metabolic process; feeding behavior; and monoamine transport. Located in synaptic vesicle. Expressed in gonad; nervous system; and in male. Used to study amphetamine abuse and cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; type 1 diabetes mellitus; and von Hippel-Lindau disease. Is an ortholog of human SLC18A1 (solute carrier family 18 member A1) and SLC18A2 (solute carrier family 18 member A2).
daf-18 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables protein tyrosine phosphatase activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. Acts upstream of with a positive effect on protein import into nucleus. Located in several cellular components, including axon; cytoplasmic side of plasma membrane; and somatodendritic compartment. Expressed in several structures, including Z2; egg-laying apparatus; germ line; oocyte; and somatic nervous system. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and nervous system cancer (multiple). Is an ortholog of human PTEN (phosphatase and tensin homolog).
kel-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Expressed in head and tail. Is predicted to encode a protein with the following domains: Kelch-type beta propeller; BTB And C-terminal Kelch; Kelch motif; SKP1/BTB/POZ domain superfamily; Kelch repeat type 1; BTB-kelch protein; BTB/POZ domain; and BTB/Kelch-associated. Is an ortholog of human KLHL18 (kelch like family member 18).
Syx18 [Search on AGR]
Drosophila melanogaster Syntaxin 18 (Syx18) encodes a SNAP receptor involved in neuromuscular synaptic transmission.
F41D3.9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in neurons based on RNA-seq studies. Is affected by several genes including
daf-12;
clk-1; and
daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647.
Y102A5C.4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Is affected by several genes including
clk-1;
pgl-1; and
daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Alovudine; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684.
Y71A12B.15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplaapaaa;
hyp3; and interfacial epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including
clk-1;
daf-18; and
sma-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies.
dhhc-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Is an ortholog of human ZDHHC18 (zinc finger DHHC-type palmitoyltransferase 18) and ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9).
CBN17935 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
CBN19215 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
Il18rap [Search on AGR]
Mus musculus PHENOTYPE: Homozygous null mice exhibit defective IL-18-mediated immune responses such as the inability of splenocytes, T helper 1 cells and neutrophils to produce cytokines in response to IL-18. [provided by MGI curators]
Cre-mab-23 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-23. In C. elegans,
mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process.
SRAE_X000103200 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
OVOC379 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
Il18rap [Search on AGR]
Rattus norvegicus Predicted to enable coreceptor activity and interleukin-18 receptor activity. Involved in cellular response to cytokine stimulus and cellular response to hydrogen peroxide. Predicted to be part of interleukin-18 receptor complex. Orthologous to human IL18RAP (interleukin 18 receptor accessory protein); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
PPA10747 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
Cbn-mab-23 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-23. In C. elegans,
mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process.
Cbr-mab-23 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-23. In C. elegans,
mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process.
CRE09637 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
CBG08211 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
Bma-mab-23 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-23. In C. elegans,
mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process.
dmd-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; mechanosensory behavior; and negative regulation of synapse pruning. Predicted to be located in nucleus. Expressed in several structures, including AVG; body wall musculature; head neurons; intestine; and vulval muscle. Is an ortholog of human DMRT1 (doublesex and
mab-3 related transcription factor 1) and DMRTC2 (DMRT like family C2).
ref-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermal cell fate specification; negative regulation of transcription by RNA polymerase II; and nematode male tail tip morphogenesis. Located in nucleus. Expressed in several structures, including E lineage cell; embryonic cell; intestine;
mc3V; and pharyngeal cell. Is an ortholog of human HES5 (hes family bHLH transcription factor 5).
Bma-mab-10 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Cre-mab-10 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Cbr-mab-10 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Ppa-mab-10 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
TMUE_1000003090 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Cbn-mab-10 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Cjp-mab-10 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Ovo-mab-10 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-10. In C. elegans,
mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development.
Prr18 [Search on AGR]
Rattus norvegicus Orthologous to human PRR18 (proline rich 18); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon.
Cjp-lin-18 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable protein kinase activity. Is an ortholog of C. elegans
lin-18. In C. elegans,
lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance.
Cre-lin-18 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable protein kinase activity. Is an ortholog of C. elegans
lin-18. In C. elegans,
lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance.
vit-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Located in cytoplasmic vesicle; vesicle lumen; and yolk granule. Expressed in embryonic cell; gonad; intestine; oocyte; and pseudocoelom.
Cbn-lin-18 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable protein kinase activity. Is an ortholog of C. elegans
lin-18. In C. elegans,
lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance.
Zfp353 [Search on AGR]
Rattus norvegicus Orthologous to human KLF18 (KLF transcription factor 18); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; amitrole.
Cbr-lin-18 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable protein kinase activity. Is an ortholog of C. elegans
lin-18. In C. elegans,
lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance.
OVOC2377 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable protein kinase activity. Is an ortholog of C. elegans
lin-18. In C. elegans,
lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance.
TRM3 [Search on AGR]
Saccharomyces cerevisiae 2'-O-ribose methyltransferase; catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs
Ppa-mab-3.2 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-3. In C. elegans,
mab-3 is involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis.
Bma-gcy-18 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable protein kinase activity. Predicted to be involved in cyclic nucleotide biosynthetic process and intracellular signal transduction. Is an ortholog of C. elegans
gcy-18. In C. elegans,
gcy-18 is involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis.
Cre-daf-18 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans
daf-18. In C. elegans,
daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis.
Cjp-mab-3 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-3. In C. elegans,
mab-3 is involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis.
C18h18orf63 [Search on AGR]
Rattus norvegicus Orthologous to human C18orf63 (chromosome 18 open reading frame 63); INTERACTS WITH 2-palmitoylglycerol (ortholog); tebuconazole (ortholog).
Bm2938 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Enriched in digestive tract based on proteomic studies. Is predicted to encode a protein with the following domains: Alpha/Beta hydrolase fold; Alpha/beta hydrolase domain containing 18; and Alpha/beta hydrolase domain-containing protein 18. Is an ortholog of C. elegans C54G4.7.
Cbr-daf-18 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans
daf-18. In C. elegans,
daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis.
SRAE_X000132800 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans
daf-18. In C. elegans,
daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis.
Y47D3B.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in hypodermis and rectal epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including
eat-2;
clk-1; and
dpy-7 based on microarray and RNA-seq studies. Is affected by nine chemicals including multi-walled carbon nanotube; Alovudine; and Zidovudine based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like.
Cbn-mab-3 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-3. In C. elegans,
mab-3 is involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis.
Ovo-mab-3 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans
mab-3. In C. elegans,
mab-3 is involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis.
clec-128 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enriched in NSM based on tiling array studies. Is affected by
daf-2;
daf-18; and
eat-2 based on RNA-seq and microarray studies. Is affected by resveratrol; fluoranthene; and adsorbable organic bromine compound based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; Phosphorylation site; and C-type lectin-like.
npp-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to be a structural constituent of nuclear pore. Predicted to be involved in poly(A)+ mRNA export from nucleus; protein import into nucleus; and transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery. Located in kinetochore and nuclear membrane. Part of nuclear pore. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome and nephrotic syndrome type 18. Is an ortholog of human NUP133 (nucleoporin 133).
slc-25A18.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable L-aspartate transmembrane transporter activity and L-glutamate transmembrane transporter activity. Predicted to be involved in L-glutamate transmembrane transport; aspartate transmembrane transport; and malate-aspartate shuttle. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 3. Is an ortholog of human SLC25A18 (solute carrier family 25 member 18) and SLC25A22 (solute carrier family 25 member 22).