--- count: 1499 page: all query: mab-18 results: - allele: - class: variation id: WBVar01181635 label: gk615885 - class: variation id: WBVar00515270 label: gk292027 - class: variation id: WBVar01181575 label: gk562689 - class: variation id: WBVar00515300 label: gk292057 - class: variation id: WBVar01181545 label: gk510955 - class: variation id: WBVar01181573 label: gk407237 - class: variation id: WBVar01181585 label: gk387687 - class: variation id: WBVar01181653 label: gk867039 - class: variation id: WBVar00091743 label: ok452 - class: variation id: WBVar00515299 label: gk292056 - class: variation id: WBVar01181561 label: gk463785 - class: variation id: WBVar01181649 label: gk397487 - class: variation id: WBVar00515277 label: gk292034 - class: variation id: WBVar01181669 label: gk739326 - class: variation id: WBVar00515255 label: gk292012 - class: variation id: WBVar00515268 label: gk292025 - class: variation id: WBVar01181569 label: gk587153 - class: variation id: WBVar01181530 label: gk879400 - class: variation id: WBVar00278507 label: ns157 - class: variation id: WBVar01181617 label: gk760916 - class: variation id: WBVar01181577 label: gk621647 - class: variation id: WBVar00515279 label: gk292036 - class: variation id: WBVar01181580 label: gk910972 - class: variation id: WBVar01181613 label: gk412314 - class: variation id: WBVar01181554 label: gk616360 - class: variation id: WBVar01181558 label: gk652257 - class: variation id: WBVar01181664 label: gk363760 - class: variation id: WBVar00515288 label: gk292045 - class: variation id: WBVar01181571 label: gk314109 - class: variation id: WBVar01181583 label: gk609030 - class: variation id: WBVar00066789 label: cxTi4925 - class: variation id: WBVar00242582 label: sa503 - class: variation id: WBVar01181596 label: gk498371 - class: variation id: WBVar01181656 label: gk855103 - class: variation id: WBVar01181574 label: gk411911 - class: variation id: WBVar01181668 label: gk651401 - class: variation id: WBVar01181555 label: gk596262 - class: variation id: WBVar01181662 label: gk664794 - class: variation id: WBVar00088180 label: ju441 - class: variation id: WBVar01181557 label: gk538670 - class: variation id: WBVar01181565 label: gk762995 - class: variation id: WBVar01181587 label: gk414693 - class: variation id: WBVar00515297 label: gk292054 - class: variation id: WBVar01181542 label: gk464387 - class: variation id: WBVar00515271 label: gk292028 - class: variation id: WBVar01181544 label: gk702659 - class: variation id: WBVar01181584 label: gk773404 - class: variation id: WBVar02150415 label: tm12888 - class: variation id: WBVar01181658 label: gk836096 - class: variation id: WBVar00515253 label: gk292010 - class: variation id: WBVar00515302 label: gk292059 - class: variation id: WBVar00248902 label: sy66 - class: variation id: WBVar01181671 label: gk508295 - class: variation id: WBVar00257926 label: ttTi17114 - class: variation id: WBVar01181621 label: gk422880 - class: variation id: WBVar01181592 label: gk555355 - class: variation id: WBVar01181605 label: gk316562 - class: variation id: WBVar00515275 label: gk292032 - class: variation id: WBVar01181559 label: gk851870 - class: variation id: WBVar01181615 label: gk353497 - class: variation id: WBVar00515281 label: gk292038 - class: variation id: WBVar00515294 label: gk292051 - class: variation id: WBVar01181660 label: gk674177 - class: variation id: WBVar00515284 label: gk292041 - class: variation id: WBVar01181563 label: gk712939 - class: variation id: WBVar00143714 label: e1062 - class: variation id: WBVar01181533 label: gk516588 - class: variation id: WBVar00000565 label: bx23 - class: variation id: WBVar01181667 label: gk363761 - class: variation id: WBVar01181622 label: gk411451 - class: variation id: WBVar01181628 label: gk455146 - class: variation id: WBVar01181643 label: gk626367 - class: variation id: WBVar01181614 label: gk764672 - class: variation id: WBVar01181652 label: gk851871 - class: variation id: WBVar01181620 label: gk858301 - class: variation id: WBVar01181610 label: gk821964 - class: variation id: WBVar01181665 label: gk439754 - class: variation id: WBVar01181591 label: gk396292 - class: variation id: WBVar01181549 label: gk624569 - class: variation id: WBVar01181640 label: gk432963 - class: variation id: WBVar01181636 label: gk618752 - class: variation id: WBVar01181654 label: gk532451 - class: variation id: WBVar01181601 label: gk586270 - class: variation id: WBVar01181578 label: gk827692 - class: variation id: WBVar00144828 label: e2429 - class: variation id: WBVar00142928 label: e41 - class: variation id: WBVar01181535 label: gk431999 - class: variation id: WBVar01181529 label: gk354655 - class: variation id: WBVar00515303 label: gk292060 - class: variation id: WBVar01181514 label: gk478733 - class: variation id: WBVar00000438 label: bc52 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar01181524 label: gk847432 - class: variation id: WBVar01181526 label: gk734660 - class: variation id: WBVar01181627 label: gk719473 - class: variation id: WBVar01181597 label: gk798332 - class: variation id: WBVar00515276 label: gk292033 - class: variation id: WBVar01181525 label: gk739324 - class: variation id: WBVar00515269 label: gk292026 - class: variation id: WBVar01181673 label: gk825126 - class: variation id: WBVar00275145 label: we4 - class: variation id: WBVar01181528 label: gk867643 - class: variation id: WBVar00515280 label: gk292037 - class: variation id: WBVar01181644 label: gk637926 - class: variation id: WBVar00144308 label: e1796 - class: variation id: WBVar01181537 label: gk872236 - class: variation id: WBVar01181642 label: gk788261 - class: variation id: WBVar01181547 label: gk432000 - class: variation id: WBVar00515295 label: gk292052 - class: variation id: WBVar00275461 label: zd91 - class: variation id: WBVar00094976 label: ot346 - class: variation id: WBVar00515256 label: gk292013 - class: variation id: WBVar00515266 label: gk292023 - class: variation id: WBVar01181641 label: gk526190 - class: variation id: WBVar02139989 label: h3887 - class: variation id: WBVar00143364 label: e643 - class: variation id: WBVar01181536 label: gk473911 - class: variation id: WBVar01181674 label: gk733962 - class: variation id: WBVar01181527 label: gk412840 - class: variation id: WBVar00515254 label: gk292011 - class: variation id: WBVar01181538 label: gk801754 - class: variation id: WBVar01181595 label: gk619903 - class: variation id: WBVar01181645 label: gk717622 - class: variation id: WBVar00088464 label: ky664 - class: variation id: WBVar01181519 label: gk824052 - class: variation id: WBVar00515267 label: gk292024 - class: variation id: WBVar01181539 label: gk548838 - class: variation id: WBVar01181598 label: gk343832 - class: variation id: WBVar00515304 label: gk292061 - class: variation id: WBVar00515292 label: gk292049 - class: variation id: WBVar01181572 label: gk532450 - class: variation id: WBVar01181566 label: gk902904 - class: variation id: WBVar00515282 label: gk292039 - class: variation id: WBVar01181564 label: gk669776 - class: variation id: WBVar01181602 label: gk680106 - class: variation id: WBVar01181616 label: gk387688 - class: variation id: WBVar01181543 label: gk739325 - class: variation id: WBVar00515298 label: gk292055 - class: variation id: WBVar01181624 label: gk664793 - class: variation id: WBVar01181648 label: gk653040 - class: variation id: WBVar00515257 label: gk292014 - class: variation id: WBVar01181516 label: gk610032 - class: variation id: WBVar01181603 label: gk887956 - class: variation id: WBVar01181629 label: gk584758 - class: variation id: WBVar00089259 label: mw105 - class: variation id: WBVar01181541 label: gk827691 - class: variation id: WBVar00515296 label: gk292053 - class: variation id: WBVar00515265 label: gk292022 - class: variation id: WBVar01181638 label: gk696795 - class: variation id: WBVar01181520 label: gk360446 - class: variation id: WBVar01181661 label: gk439753 - class: variation id: WBVar01181515 label: gk628565 - class: variation id: WBVar00088193 label: k121 - class: variation id: WBVar00143804 label: e1178 - class: variation id: WBVar00317401 label: ot292 - class: variation id: WBVar01181576 label: gk682362 - class: variation id: WBVar01181522 label: gk493936 - class: variation id: WBVar01181570 label: gk742466 - class: variation id: WBVar01181594 label: gk805908 - class: variation id: WBVar01181630 label: gk644534 - class: variation id: WBVar01181600 label: gk449541 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar00515286 label: gk292043 - class: variation id: WBVar01181589 label: gk667374 - class: variation id: WBVar00094952 label: ot266 - class: variation id: WBVar01181626 label: gk633080 - class: variation id: WBVar01181548 label: gk776810 - class: variation id: WBVar00515262 label: gk292019 - class: variation id: WBVar01181556 label: gk322040 - class: variation id: WBVar00515283 label: gk292040 - class: variation id: WBVar01181550 label: gk418411 - class: variation id: WBVar01181567 label: gk819750 - class: variation id: WBVar01181619 label: gk604608 - class: variation id: WBVar01181637 label: gk554942 - class: variation id: WBVar01181553 label: gk357556 - class: variation id: WBVar01181650 label: gk881155 - class: variation id: WBVar00515258 label: gk292015 - class: variation id: WBVar00515278 label: gk292035 - class: variation id: WBVar00515301 label: gk292058 - class: variation id: WBVar00515289 label: gk292046 - class: variation id: WBVar00054272 label: cr2 - class: variation id: WBVar00515260 label: gk292017 - class: variation id: WBVar00088183 label: ju478 - class: variation id: WBVar01181551 label: gk602437 - class: variation id: WBVar00088189 label: k109 - class: variation id: WBVar01181523 label: gk493937 - class: variation id: WBVar00143369 label: e648 - class: variation id: WBVar02139991 label: h15657 - class: variation id: WBVar01487580 label: gk951842 - class: variation id: WBVar01181588 label: gk786959 - class: variation id: WBVar02124998 label: ky112 - class: variation id: WBVar00515263 label: gk292020 - class: variation id: WBVar00515274 label: gk292031 - class: variation id: WBVar01181521 label: gk893037 - class: variation id: WBVar01181659 label: gk856615 - class: variation id: WBVar00248959 label: sy281 - class: variation id: WBVar01181663 label: gk892492 - class: variation id: WBVar01181582 label: gk312707 - class: variation id: WBVar01181579 label: gk351344 - class: variation id: WBVar00515261 label: gk292018 - class: variation id: WBVar00515251 label: gk292008 - class: variation id: WBVar01181581 label: gk703662 - class: variation id: WBVar01181599 label: gk764307 - class: variation id: WBVar00090516 label: n2550 - class: variation id: WBVar01181670 label: gk433639 - class: variation id: WBVar00088181 label: ju468 - class: variation id: WBVar00088204 label: k143 - class: variation id: WBVar01181607 label: gk846936 - class: variation id: WBVar00515264 label: gk292021 - class: variation id: WBVar00515290 label: gk292047 - class: variation id: WBVar01181531 label: gk424337 - class: variation id: WBVar01181666 label: gk517766 - class: variation id: WBVar01181672 label: gk420906 - class: variation id: WBVar01181517 label: gk398799 - class: variation id: WBVar01181593 label: gk585900 - class: variation id: WBVar00515273 label: gk292030 - class: variation id: WBVar01181618 label: gk588408 - class: variation id: WBVar02139990 label: h5871 - class: variation id: WBVar00094958 label: ot276 - class: variation id: WBVar01181546 label: gk463168 - class: variation id: WBVar01181552 label: gk619902 - class: variation id: WBVar01181540 label: gk425102 - class: variation id: WBVar00515305 label: gk292062 - class: variation id: WBVar01181623 label: gk728762 - class: variation id: WBVar00515259 label: gk292016 - class: variation id: WBVar01181532 label: gk733960 - class: variation id: WBVar01474328 label: cxTi10671 - class: variation id: WBVar01181647 label: gk671038 - class: variation id: WBVar01181632 label: gk433130 - class: variation id: WBVar01181611 label: gk584757 - class: variation id: WBVar00515272 label: gk292029 - class: variation id: WBVar01181562 label: gk689867 - class: variation id: WBVar01181634 label: gk850350 - class: variation id: WBVar01181633 label: gk691605 - class: variation id: WBVar01181612 label: gk615227 - class: variation id: WBVar01181631 label: gk388542 - class: variation id: WBVar00515293 label: gk292050 - class: variation id: WBVar01181639 label: gk554943 - class: variation id: WBVar01181604 label: gk333458 - class: variation id: WBVar00515252 label: gk292009 - class: variation id: WBVar01181608 label: gk586767 - class: variation id: WBVar01181675 label: gk718181 - class: variation id: WBVar01181657 label: gk695088 - class: variation id: WBVar01181646 label: gk474914 - class: variation id: WBVar00515287 label: gk292044 - class: variation id: WBVar01181606 label: gk850836 - class: variation id: WBVar01181534 label: gk429488 - class: variation id: WBVar01181651 label: gk422335 - class: variation id: WBVar01181560 label: gk618045 - class: variation id: WBVar00515291 label: gk292048 - class: variation id: WBVar01181518 label: gk629294 - class: variation id: WBVar01181609 label: gk588407 - class: variation id: WBVar00143686 label: e1022 - class: variation id: WBVar01181655 label: gk938328 - class: variation id: WBVar01181625 label: gk821455 - class: variation id: WBVar01181568 label: gk733961 - class: variation id: WBVar01181586 label: gk700999 - class: variation id: WBVar00515285 label: gk292042 - class: variation id: WBVar01181590 label: gk428712 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; negative regulation of distal tip cell migration; and positive regulation of glial cell differentiation. Located in cytoplasm and nucleus. Expressed in several structures, including Y.p; distal tip cell; head muscle; neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including bilateral optic nerve hypoplasia; eye disease (multiple); and glucose intolerance. Is an ortholog of human PAX6 (paired box 6). label: vab-3 legacy_description: vab-3 encodes a homeodomain protein that is the C. elegans Pax-6 orthologue; during development, vab-3 activity is required for proper patterning of anterior (head) hypodermal cells; vab-3 effects head development, in part, through positively regulating transcription of ceh-32, a Six/sine oculis class homeobox gene coexpressed with vab-3 in head hypodermis; vab-3 is also required for epidermal morphogenesis, epidermal cell fates, gonad cell migration and the development of sensory structures in the male tail; multiple genetic pathways including the Wnt signalling pathway and the homeobox gene, egl-5, regulate the expression of vab-3. merged_into: ~ name: class: gene highlight: other_names: - mab-18 id: WBGene00006870 label: vab-3 other_names: - F14F3.1 - mab-18 - lin-20 - sax-4 - pax-6 - CELE_F14F3.1 - CE28216 - F14F3.1a.2 - F14F3.1b - F14F3.1a.1 - F14F3.1a - F14F3.1c - CE28217 - F14F3.1b.1 - F14F3.1c.1 - CE24899 taxonomy: c_elegans other_names: - F14F3.1 - mab-18 - lin-20 - sax-4 - pax-6 - CELE_F14F3.1 - CE28216 - F14F3.1a.2 - F14F3.1b - F14F3.1a.1 - F14F3.1a - F14F3.1c - CE28217 - F14F3.1b.1 - F14F3.1c.1 - CE24899 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006870 - allele: - class: variation id: WBVar00143859 label: e1249 dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: mab-6 legacy_description: mab-6 was identified in screens for mutations that decrease male mating efficiency; mab-6 is defined by a single allele that results in deformity of the male copulatory bursa and a protruding vulva in hermaphrodites. merged_into: ~ name: class: gene highlight: description_all: - mab-6 was identified in screens for mutations that decrease male mating efficiency; mab-6 is defined id: WBGene00003103 label: mab-6 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003103 - allele: - class: variation id: WBVar02126832 label: h6313 - class: variation id: WBVar00625078 label: gk472969 - class: variation id: WBVar01499416 label: gk963438 - class: variation id: WBVar00625066 label: gk530489 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar00625070 label: gk315856 - class: variation id: WBVar00625065 label: gk639578 - class: variation id: WBVar02126831 label: h5648 - class: variation id: WBVar00625073 label: gk488484 - class: variation id: WBVar01499985 label: gk964159 - class: variation id: WBVar00330077 label: gk106834 - class: variation id: WBVar00625075 label: gk381164 - class: variation id: WBVar00625069 label: gk734717 - class: variation id: WBVar00625074 label: gk742011 - class: variation id: WBVar00625071 label: gk513013 - class: variation id: WBVar00625072 label: gk801818 - class: variation id: WBVar00625077 label: gk743275 - class: variation id: WBVar00625068 label: gk347165 - class: variation id: WBVar00330078 label: gk106835 - class: variation id: WBVar00625079 label: gk346594 - class: variation id: WBVar00625067 label: gk323950 - class: variation id: WBVar00330079 label: gk106836 - class: variation id: WBVar00625076 label: gk604696 - class: variation id: WBVar00251563 label: tm2718 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. Located in nucleus. Expressed in hyp7 syncytium; intestine; pharynx; ray; and socket cell. label: mab-31 legacy_description: mab-31 encodes a novel protein that is highly conserved amongst nematodes; mab-31 functions in the TGF-beta signaling pathway to regulate the male tail ray patterning process, specifically the positioning of the R7-derived ray cell cluster; a mab-31::gfp reporter is expressed in a wide variety of tissues, including the intestine, hypodermis, pharynx, and neuronal support cells; in males, mab-31::gfp is also seen in the ray structural cells; a MAB-31::GFP localizes to the nucleus. merged_into: ~ name: class: gene highlight: description_all: - mab-31 encodes a novel protein that is highly conserved amongst nematodes; mab-31 functions in the TGF-beta - male tail ray patterning process, specifically the positioning of the R7-derived ray cell cluster; a mab - variety of tissues, including the intestine, hypodermis, pharynx, and neuronal support cells; in males, mab - -31::gfp is also seen in the ray structural cells; a MAB-31::GFP localizes to the nucleus. id: WBGene00021834 label: mab-31 other_names: - Y54E10A.16 - CELE_Y54E10A.16 - Y54E10A.16.1 - CE24445 - Y54E10A.16 taxonomy: c_elegans other_names: - Y54E10A.16 - CELE_Y54E10A.16 - Y54E10A.16.1 - CE24445 - Y54E10A.16 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00021834 - allele: - class: variation id: WBVar00089197 label: mu15 - class: variation id: WBVar00758133 label: gk749771 - class: variation id: WBVar00758136 label: gk345611 - class: variation id: WBVar00374690 label: gk151447 - class: variation id: WBVar00758141 label: gk815988 - class: variation id: WBVar00758161 label: gk569840 - class: variation id: WBVar00758131 label: gk328676 - class: variation id: WBVar00758152 label: gk388410 - class: variation id: WBVar01489715 label: gk953978 - class: variation id: WBVar00758128 label: gk508442 - class: variation id: WBVar00144557 label: e2093 - class: variation id: WBVar00374684 label: gk151441 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00758160 label: gk498034 - class: variation id: WBVar00374687 label: gk151444 - class: variation id: WBVar00253007 label: tm4619 - class: variation id: WBVar00758135 label: gk757422 - class: variation id: WBVar00758130 label: gk412644 - class: variation id: WBVar00758129 label: gk624198 - class: variation id: WBVar00758162 label: gk659137 - class: variation id: WBVar00758172 label: gk524577 - class: variation id: WBVar00758132 label: gk343473 - class: variation id: WBVar00374694 label: gk151451 - class: variation id: WBVar00758171 label: gk537343 - class: variation id: WBVar00146159 label: gk862 - class: variation id: WBVar00758163 label: gk611577 - class: variation id: WBVar00758139 label: gk320304 - class: variation id: WBVar00144395 label: e1921 - class: variation id: WBVar00758140 label: gk875977 - class: variation id: WBVar00758151 label: gk459827 - class: variation id: WBVar00758153 label: gk650264 - class: variation id: WBVar00758142 label: gk863820 - class: variation id: WBVar00758127 label: gk480392 - class: variation id: WBVar00758164 label: gk836882 - class: variation id: WBVar00758148 label: gk679621 - class: variation id: WBVar00758159 label: gk778564 - class: variation id: WBVar00758134 label: gk461291 - class: variation id: WBVar01498940 label: gk962682 - class: variation id: WBVar00758158 label: gk816796 - class: variation id: WBVar00374695 label: gk151452 - class: variation id: WBVar00758138 label: gk863819 - class: variation id: WBVar00758145 label: gk665484 - class: variation id: WBVar00758150 label: gk873490 - class: variation id: WBVar01477840 label: gk942098 - class: variation id: WBVar00758155 label: gk461292 - class: variation id: WBVar00758166 label: gk488580 - class: variation id: WBVar00143854 label: e1240 - class: variation id: WBVar00758144 label: gk353674 - class: variation id: WBVar00297086 label: otn265 - class: variation id: WBVar00146238 label: gk1026 - class: variation id: WBVar00758156 label: gk488579 - class: variation id: WBVar01499017 label: gk962798 - class: variation id: WBVar00144634 label: e2209 - class: variation id: WBVar00374692 label: gk151449 - class: variation id: WBVar00758169 label: gk606972 - class: variation id: WBVar00374686 label: gk151443 - class: variation id: WBVar00259522 label: ttTi23742 - class: variation id: WBVar00374688 label: gk151445 - class: variation id: WBVar00758143 label: gk448816 - class: variation id: WBVar00758168 label: gk713651 - class: variation id: WBVar00374685 label: gk151442 - class: variation id: WBVar00374691 label: gk151448 - class: variation id: WBVar02130533 label: h15858 - class: variation id: WBVar00144637 label: e2212 - class: variation id: WBVar00758126 label: gk823697 - class: variation id: WBVar00758137 label: gk463333 - class: variation id: WBVar00758146 label: gk751255 - class: variation id: WBVar00374689 label: gk151446 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00374693 label: gk151450 - class: variation id: WBVar00758149 label: gk646078 - class: variation id: WBVar00142573 label: cxTi10592 - class: variation id: WBVar02130532 label: h14365 - class: variation id: WBVar00758157 label: gk611576 - class: variation id: WBVar00758173 label: gk716844 - class: variation id: WBVar00758167 label: gk744600 - class: variation id: WBVar00758165 label: gk365315 - class: variation id: WBVar00758154 label: gk314157 - class: variation id: WBVar00758170 label: gk324382 - class: variation id: WBVar00758147 label: gk745316 - class: variation id: WBVar01499234 label: gk963142 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis. Acts upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Expressed in ADF; SMD; and in male. label: mab-3 legacy_description: mab-3 encodes a DM (Doublesex and MAB-3) domain-containing protein; during development, MAB-3 plays a role in several aspects of male development; specifically, genetic studies indicate that MAB-3 likely augments the functions of the MAB-5 and EGL-5 homeodomain proteins by acting as a transcriptional repressor of ref-1, which encodes a basic helix-loop-helix (bHLH) protein that negatively regulates expression of the LIN-32 proneural bHLH protein required for male sensory ray development; in addition, MAB-3 regulates yolk protein expression in the intestine; mab-3 expression in the intestine is negatively regulated by TRA-1A, the terminal protein in the sex determination pathway; a mab-3::GFP promoter fusion is expressed in neurons and hypodermal cells as well as in the intestine; expression of the male-specific form of Drosophila Doublesex can rescue mab-3-related defects in C. elegans. merged_into: ~ name: class: gene highlight: description_all: - mab-3 encodes a DM (Doublesex and MAB-3) domain-containing protein; during development, MAB-3 plays a - role in several aspects of male development; specifically, genetic studies indicate that MAB-3 likely - -3 regulates yolk protein expression in the intestine; mab-3 expression in the intestine is negatively - regulated by TRA-1A, the terminal protein in the sex determination pathway; a mab-3::GFP promoter fusion - as well as in the intestine; expression of the male-specific form of Drosophila Doublesex can rescue mab id: WBGene00003100 label: mab-3 other_names: - Y53C12B.5 - CELE_Y53C12B.5 - CE14902 - Y53C12B.5a - CE51560 - Y53C12B.5b.1 - Y53C12B.5b.2 - Y53C12B.5a.1 - Y53C12B.5b taxonomy: c_elegans other_names: - Y53C12B.5 - CELE_Y53C12B.5 - CE14902 - Y53C12B.5a - CE51560 - Y53C12B.5b.1 - Y53C12B.5b.2 - Y53C12B.5a.1 - Y53C12B.5b page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003100 - allele: - class: variation id: WBVar01100541 label: gk572999 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01485686 label: gk949946 - class: variation id: WBVar01100547 label: gk375490 - class: variation id: WBVar01100546 label: gk678118 - class: variation id: WBVar00488024 label: gk264781 - class: variation id: WBVar01485685 label: gk949945 - class: variation id: WBVar01499566 label: gk963637 - class: variation id: WBVar01100548 label: gk348222 - class: variation id: WBVar01499709 label: gk963809 - class: variation id: WBVar01100542 label: gk937617 - class: variation id: WBVar01100544 label: gk450198 - class: variation id: WBVar01100545 label: gk745529 - class: variation id: WBVar01100543 label: gk640001 - class: variation id: WBVar01499446 label: gk963489 - class: variation id: WBVar01498549 label: gk963304 - class: variation id: WBVar01100549 label: gk696766 - class: variation id: WBVar01100540 label: gk527892 - class: variation id: WBVar00488023 label: gk264780 - class: variation id: WBVar01498958 label: gk962705 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in extracellular space. Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain family 18 member B); and CLEC18C (C-type lectin domain family 18 member C). label: scl-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human CLEC18A (C-type lectin domain family 18 member A); CLEC18B (C-type lectin domain - family 18 member B); and CLEC18C (C-type lectin domain family 18 member C). id: WBGene00012816 label: scl-21 other_names: - Y43F8B.5 - CELE_Y43F8B.5 - CE21890 - Y43F8B.5 - Y43F8B.5.1 taxonomy: c_elegans other_names: - Y43F8B.5 - CELE_Y43F8B.5 - CE21890 - Y43F8B.5 - Y43F8B.5.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00012816 - allele: - class: variation id: WBVar00089062 label: mn142 - class: variation id: WBVar00089046 label: mn122 - class: variation id: WBVar00089057 label: mn136 dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: let-18 legacy_description: let-18 was identified in a screen for X-chromosome linked genes causing sterilty or lethality; let-18 mutants exhibit embryonic and late larval lethality. merged_into: ~ name: class: gene highlight: description_all: - let-18 was identified in a screen for X-chromosome linked genes causing sterilty or lethality; let-18 id: WBGene00002294 label: let-18 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00002294 - allele: - class: variation id: WBVar00000569 label: bx27 dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: mab-25 legacy_description: mab-25 is defined by a single mutation that results in temperature-sensitive male tail abnormalities and lethality. merged_into: ~ name: class: gene highlight: description_all: - mab-25 is defined by a single mutation that results in temperature-sensitive male tail abnormalities id: WBGene00003116 label: mab-25 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003116 - allele: - class: variation id: WBVar00377512 label: gk154269 - class: variation id: WBVar00377510 label: gk154267 - class: variation id: WBVar00766358 label: gk436446 - class: variation id: WBVar00766360 label: gk390502 - class: variation id: WBVar00766363 label: gk374737 - class: variation id: WBVar00377511 label: gk154268 - class: variation id: WBVar00766356 label: gk536206 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00766368 label: gk924251 - class: variation id: WBVar00766353 label: gk484974 - class: variation id: WBVar00766355 label: gk536205 - class: variation id: WBVar01498940 label: gk962682 - class: variation id: WBVar00377507 label: gk154264 - class: variation id: WBVar00766352 label: gk469716 - class: variation id: WBVar00377509 label: gk154266 - class: variation id: WBVar00766359 label: gk645698 - class: variation id: WBVar00377508 label: gk154265 - class: variation id: WBVar00307716 label: otn10895 - class: variation id: WBVar00766351 label: gk779099 - class: variation id: WBVar00766354 label: gk836332 - class: variation id: WBVar00766361 label: gk580569 - class: variation id: WBVar00766365 label: gk610259 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00766366 label: gk633818 - class: variation id: WBVar00766357 label: gk790090 - class: variation id: WBVar00766364 label: gk845410 - class: variation id: WBVar00092767 label: ok1557 - class: variation id: WBVar00766367 label: gk791678 - class: variation id: WBVar00766362 label: gk896634 - class: variation id: WBVar00377513 label: gk154270 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in neuropeptide signaling pathway. Expressed in intestine; neurons; rectal gland cell; and spermatheca. label: nlp-18 legacy_description: nlp-18 encodes four predicted neuropeptide-like proteins; in C. elegans, nlp-18 is part of the FAFA neuropeptide family that also contains nlp-20; nlp-18 is expressed in a variety of neurons, including ASI, NSM, four head neurons, two tail neurons, and two anterior pharyngeal neurons; nlp-18 expression is also detected in the spermatheca, the rectal gland, and the intestine; as loss of nlp-18 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-18-encoded peptides in development and/or behavior is not yet known. merged_into: ~ name: class: gene highlight: description_all: - nlp-18 encodes four predicted neuropeptide-like proteins; in C. elegans, nlp-18 is part of the FAFA neuropeptide - family that also contains nlp-20; nlp-18 is expressed in a variety of neurons, including ASI, NSM, four - head neurons, two tail neurons, and two anterior pharyngeal neurons; nlp-18 expression is also detected - in the spermatheca, the rectal gland, and the intestine; as loss of nlp-18 activity via large-scale - RNAi screens does not result in any obvious abnormalities, the precise role of nlp-18-encoded peptides id: WBGene00003756 label: nlp-18 other_names: - F33A8.2 - CELE_F33A8.2 - F33A8.2.1 - CE32885 - F33A8.2 taxonomy: c_elegans other_names: - F33A8.2 - CELE_F33A8.2 - F33A8.2.1 - CE32885 - F33A8.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003756 - allele: - class: variation id: WBVar00822724 label: gk323769 - class: variation id: WBVar00396330 label: gk173087 - class: variation id: WBVar00822732 label: gk782323 - class: variation id: WBVar00822723 label: gk909346 - class: variation id: WBVar00248921 label: sy155 - class: variation id: WBVar00822728 label: gk888177 - class: variation id: WBVar00000583 label: bx53 - class: variation id: WBVar00396333 label: gk173090 - class: variation id: WBVar00822727 label: gk751968 - class: variation id: WBVar00822725 label: gk392720 - class: variation id: WBVar00396328 label: gk173085 - class: variation id: WBVar00396332 label: gk173089 - class: variation id: WBVar02131906 label: h5273 - class: variation id: WBVar00396329 label: gk173086 - class: variation id: WBVar00000580 label: bx43 - class: variation id: WBVar00822726 label: gk409354 - class: variation id: WBVar00396331 label: gk173088 - class: variation id: WBVar00822730 label: gk782322 - class: variation id: WBVar00396327 label: gk173084 - class: variation id: WBVar00822731 label: gk715831 - class: variation id: WBVar00000578 label: bx41 - class: variation id: WBVar00822729 label: gk888178 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis. Expressed in several structures, including PVC; VA2; hyp7 syncytium; ray 6; and sensory neurons. Human ortholog(s) of this gene implicated in coloboma and syndromic microphthalmia 14. Is an ortholog of human MAB21L1 (mab-21 like 1) and MAB21L2 (mab-21 like 2). label: mab-21 legacy_description: mab-21 encodes a novel protein that is a member of a highly conserved family of proteins with Drosophila and vertebrate orthologs; MAB-21 is cell-autonomously required for specifying the identity of sensory ray 6 in the male tail, and also for backward locomotion, normal body morphology, fecundity, and embryonic morphogenesis; MAB-21 expression begins in embryonic hypodermal cells and continues in larval and adult animals in hypodermis, anterior and ventral cord neurons, some body wall muscles, and ray cells. merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human MAB21L1 (mab-21 like 1) and MAB21L2 (mab-21 like 2). - mab-21 encodes a novel protein that is a member of a highly conserved family of proteins with Drosophila - and vertebrate orthologs; MAB-21 is cell-autonomously required for specifying the identity of sensory - ", and also for backward locomotion, normal body morphology, fecundity, and embryonic morphogenesis; MAB" id: WBGene00003112 label: mab-21 other_names: - F35G12.6 - CELE_F35G12.6 - F35G12.6 - CE32651 - F35G12.6.1 taxonomy: c_elegans other_names: - F35G12.6 - CELE_F35G12.6 - F35G12.6 - CE32651 - F35G12.6.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003112 - allele: - class: variation id: WBVar00275176 label: wk68 dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: sma-18 legacy_description: sma-18 was identified in screens for mutations that result in small body size; sma-18 is defined by a single allele that, when homozygous, results in animals that are ~40% shorter than wild type; genetic epistasis analysis places sma-18 downstream of both dbl-1 and lon-1 in the Sma/TGFbeta signaling pathway. merged_into: ~ name: class: gene highlight: description_all: - sma-18 was identified in screens for mutations that result in small body size; sma-18 is defined by a - homozygous, results in animals that are ~40% shorter than wild type; genetic epistasis analysis places sma-18 id: WBGene00004870 label: sma-18 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004870 - allele: - class: variation id: WBVar01111887 label: gk707924 - class: variation id: WBVar01111888 label: gk451602 - class: variation id: WBVar00492021 label: gk268778 - class: variation id: WBVar01111875 label: gk553507 - class: variation id: WBVar01111882 label: gk714975 - class: variation id: WBVar01111879 label: gk874962 - class: variation id: WBVar01111885 label: gk432935 - class: variation id: WBVar01111878 label: gk522528 - class: variation id: WBVar01111884 label: gk511362 - class: variation id: WBVar01111883 label: gk467320 - class: variation id: WBVar00492022 label: gk268779 - class: variation id: WBVar01111881 label: gk678768 - class: variation id: WBVar01111876 label: gk885113 - class: variation id: WBVar01111880 label: gk838426 - class: variation id: WBVar01486127 label: gk950387 - class: variation id: WBVar01111877 label: gk522527 - class: variation id: WBVar01498638 label: gk963652 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar01495464 label: gk959727 - class: variation id: WBVar01111886 label: gk554410 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by daf-18 and vit-5 based on RNA-seq studies. label: M02E1.4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by daf-18 and vit-5 based on RNA-seq studies. id: WBGene00284848 label: M02E1.4 other_names: - M02E1.4 - CELE_M02E1.4 - M02E1.4 - CE52605 - M02E1.4.1 taxonomy: c_elegans other_names: - M02E1.4 - CELE_M02E1.4 - M02E1.4 - CE52605 - M02E1.4.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00284848 - allele: - class: variation id: WBVar00277376 label: ok5529 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar00653613 label: gk662106 - class: variation id: WBVar00653619 label: gk739920 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00653614 label: gk890432 - class: variation id: WBVar00339595 label: gk116352 - class: variation id: WBVar00339597 label: gk116354 - class: variation id: WBVar00253934 label: ttTi3027 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar00339594 label: gk116351 - class: variation id: WBVar00339592 label: gk116349 - class: variation id: WBVar00339593 label: gk116350 - class: variation id: WBVar00653611 label: gk807963 - class: variation id: WBVar01500105 label: gk964316 - class: variation id: WBVar00653618 label: gk636008 - class: variation id: WBVar00653612 label: gk917340 - class: variation id: WBVar00653620 label: gk433676 - class: variation id: WBVar00249387 label: tm339 - class: variation id: WBVar00653616 label: gk842792 - class: variation id: WBVar02127972 label: h15374 - class: variation id: WBVar00653617 label: gk466473 - class: variation id: WBVar00339596 label: gk116353 - class: variation id: WBVar00653615 label: gk593062 - class: variation id: WBVar00653610 label: gk900328 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar00653609 label: gk755269 - class: variation id: WBVar00092880 label: ok1672 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Involved in maintenance of dauer; negative regulation of insulin receptor signaling pathway; and regulation of dauer entry. Expressed in several structures, including coelomocyte; gonad; head muscle; nerve ring; and neurons. label: ins-18 legacy_description: ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; in addition, daf-7; ins-18 doubly mutant animals show dauer maintenance defects, suggesting that INS-18 activity is required to properly maintain the dauer developmental state; ins-18::gfp reporters are expressed in neurons and the intestine. merged_into: ~ name: class: gene highlight: description_all: - ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only - peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 - degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 - dauer maintenance defects, suggesting that INS-18 activity is required to properly maintain the dauer - developmental state; ins-18::gfp reporters are expressed in neurons and the intestine. id: WBGene00002101 label: ins-18 other_names: - T28B8.2 - Ceinsulin-1 - CELE_T28B8.2 - ins-1 - igf-1 - T28B8.2.1 - T28B8.2 - CE27217 taxonomy: c_elegans other_names: - T28B8.2 - Ceinsulin-1 - CELE_T28B8.2 - ins-1 - igf-1 - T28B8.2.1 - T28B8.2 - CE27217 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00002101 - allele: - class: variation id: WBVar01043909 label: gk845710 - class: variation id: WBVar01043920 label: gk914796 - class: variation id: WBVar01500097 label: gk964304 - class: variation id: WBVar00253026 label: tm4650 - class: variation id: WBVar01500209 label: gk964452 - class: variation id: WBVar01499215 label: gk963108 - class: variation id: WBVar00469069 label: gk245826 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01043916 label: gk840680 - class: variation id: WBVar01043915 label: gk399873 - class: variation id: WBVar00000603 label: bx118 - class: variation id: WBVar01043913 label: gk712408 - class: variation id: WBVar01043910 label: gk413765 - class: variation id: WBVar01043922 label: gk851750 - class: variation id: WBVar01043918 label: gk423929 - class: variation id: WBVar01043911 label: gk447073 - class: variation id: WBVar00469070 label: gk245827 - class: variation id: WBVar01500208 label: gk964451 - class: variation id: WBVar01484622 label: gk948882 - class: variation id: WBVar01043921 label: gk460592 - class: variation id: WBVar01499450 label: gk963495 - class: variation id: WBVar01499451 label: gk963496 - class: variation id: WBVar01498725 label: gk964125 - class: variation id: WBVar01043917 label: gk318819 - class: variation id: WBVar01043919 label: gk359888 - class: variation id: WBVar00145994 label: gk664 - class: variation id: WBVar01043914 label: gk650547 - class: variation id: WBVar01043912 label: gk383392 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar00469068 label: gk245825 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable metal ion binding activity and sequence-specific DNA binding activity. Involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. Located in nucleus. Expressed in several structures, including U cell; hermaphrodite gonad; neurons; tail hypodermis; and ventral nerve cord. label: mab-23 legacy_description: mab-23 encodes a DNA binding transcription factor of the DM (DOUBLESEX/MAB-3) class that is required for morphogenesis of the posterior hypodermis, spicules, and proctodeum in male tails, for the patterning of posterior male sensory neurons, and for normal turning during male mating; mab-23 interacts with egl-5 and with a TGF-beta-related signaling pathway, while having functions independent of mab-3. merged_into: ~ name: class: gene highlight: description_all: - mab-23 encodes a DNA binding transcription factor of the DM (DOUBLESEX/MAB-3) class that is required - tails, for the patterning of posterior male sensory neurons, and for normal turning during male mating; mab - interacts with egl-5 and with a TGF-beta-related signaling pathway, while having functions independent of mab id: WBGene00003114 label: mab-23 other_names: - C32C4.5 - CELE_C32C4.5 - C32C4.5a.1 - CE40025 - CE31427 - C32C4.5b.1 - C32C4.5a - C32C4.5b taxonomy: c_elegans other_names: - C32C4.5 - CELE_C32C4.5 - C32C4.5a.1 - CE40025 - CE31427 - C32C4.5b.1 - C32C4.5a - C32C4.5b page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003114 - allele: - class: variation id: WBVar00652896 label: gk775770 - class: variation id: WBVar00339359 label: gk116116 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar02144782 label: tm7135 - class: variation id: WBVar00652898 label: gk819129 - class: variation id: WBVar00652901 label: gk454702 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar01498288 label: gk962622 - class: variation id: WBVar00652889 label: gk728854 - class: variation id: WBVar02127945 label: h5500 - class: variation id: WBVar00652892 label: gk651508 - class: variation id: WBVar00652895 label: gk493456 - class: variation id: WBVar00339356 label: gk116113 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar00092823 label: ok1615 - class: variation id: WBVar01500105 label: gk964316 - class: variation id: WBVar00652900 label: gk440044 - class: variation id: WBVar00652893 label: gk843792 - class: variation id: WBVar00652894 label: gk323165 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar01496313 label: gk960576 - class: variation id: WBVar00339358 label: gk116115 - class: variation id: WBVar00339360 label: gk116117 - class: variation id: WBVar00652890 label: gk489494 - class: variation id: WBVar00652891 label: gk516677 - class: variation id: WBVar00339357 label: gk116114 - class: variation id: WBVar00652899 label: gk400913 - class: variation id: WBVar00652897 label: gk915532 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable hydrolase activity. Is an ortholog of human ABHD18 (abhydrolase domain containing 18). label: C54G4.7 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human ABHD18 (abhydrolase domain containing 18). id: WBGene00008317 label: C54G4.7 other_names: - C54G4.7 - CELE_C54G4.7 - C54G4.7 - C54G4.7.1 - C54G4.7.3 - CE05513 - C54G4.7.2 taxonomy: c_elegans other_names: - C54G4.7 - CELE_C54G4.7 - C54G4.7 - C54G4.7.1 - C54G4.7.3 - CE05513 - C54G4.7.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00008317 - allele: - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar00338037 label: gk114794 - class: variation id: WBVar00649078 label: gk461218 - class: variation id: WBVar00338036 label: gk114793 - class: variation id: WBVar00649086 label: gk904823 - class: variation id: WBVar00649105 label: gk899321 - class: variation id: WBVar00649081 label: gk595458 - class: variation id: WBVar00649103 label: gk520777 - class: variation id: WBVar00649087 label: gk318064 - class: variation id: WBVar00649097 label: gk890422 - class: variation id: WBVar00649101 label: gk907749 - class: variation id: WBVar00604061 label: tm5798 - class: variation id: WBVar00338032 label: gk114789 - class: variation id: WBVar00649107 label: gk375557 - class: variation id: WBVar00338034 label: gk114791 - class: variation id: WBVar00338029 label: gk114786 - class: variation id: WBVar00649092 label: gk554569 - class: variation id: WBVar01473795 label: tm6017 - class: variation id: WBVar00338035 label: gk114792 - class: variation id: WBVar00649077 label: gk542948 - class: variation id: WBVar00649099 label: gk492473 - class: variation id: WBVar00649104 label: gk537965 - class: variation id: WBVar00649100 label: gk870114 - class: variation id: WBVar00649108 label: gk444402 - class: variation id: WBVar00649095 label: gk694090 - class: variation id: WBVar00338030 label: gk114787 - class: variation id: WBVar00649102 label: gk599561 - class: variation id: WBVar00649090 label: gk504634 - class: variation id: WBVar00338028 label: gk114785 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar00649083 label: gk717267 - class: variation id: WBVar00649096 label: gk496382 - class: variation id: WBVar02127807 label: h6917 - class: variation id: WBVar00649106 label: gk369322 - class: variation id: WBVar00338038 label: gk114795 - class: variation id: WBVar00649091 label: gk801186 - class: variation id: WBVar00649079 label: gk689076 - class: variation id: WBVar00649082 label: gk648029 - class: variation id: WBVar00649084 label: gk714499 - class: variation id: WBVar00338033 label: gk114790 - class: variation id: WBVar00649098 label: gk451003 - class: variation id: WBVar00649109 label: gk897145 - class: variation id: WBVar00649085 label: gk898210 - class: variation id: WBVar00649080 label: gk876573 - class: variation id: WBVar00649089 label: gk934920 - class: variation id: WBVar00649094 label: gk903004 - class: variation id: WBVar00649088 label: gk663375 - class: variation id: WBVar00338031 label: gk114788 - class: variation id: WBVar01475720 label: gk939976 - class: variation id: WBVar00649093 label: gk599066 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable heme binding activity; oxygen binding activity; and oxygen carrier activity. Predicted to be involved in oxygen transport. Located in endoplasmic reticulum. Expressed in ventral nerve cord. label: glb-18 legacy_description: glb-18 encodes a globin; glb-18 is expressed in larval and adult neurons and excretory gland cells, and in adult spermetheca and vulva; glb-18 transcription is higher in L3 and dauers than in young adults. merged_into: ~ name: class: gene highlight: description_all: - glb-18 encodes a globin; glb-18 is expressed in larval and adult neurons and excretory gland cells, and - in adult spermetheca and vulva; glb-18 transcription is higher in L3 and dauers than in young adults id: WBGene00009917 label: glb-18 other_names: - F52A8.4 - CELE_F52A8.4 - F52A8.4a - CE42769 - CE05911 - F52A8.4a.1 - F52A8.4b - F52A8.4b.1 taxonomy: c_elegans other_names: - F52A8.4 - CELE_F52A8.4 - F52A8.4a - CE42769 - CE05911 - F52A8.4a.1 - F52A8.4b - F52A8.4b.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00009917 - allele: - class: variation id: WBVar01139456 label: gk726082 - class: variation id: WBVar01139445 label: gk709646 - class: variation id: WBVar00501033 label: gk277790 - class: variation id: WBVar00501030 label: gk277787 - class: variation id: WBVar01139438 label: gk907203 - class: variation id: WBVar01139455 label: gk789828 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar00501028 label: gk277785 - class: variation id: WBVar01139439 label: gk440653 - class: variation id: WBVar01139444 label: gk734604 - class: variation id: WBVar01139449 label: gk557948 - class: variation id: WBVar01139441 label: gk682316 - class: variation id: WBVar01492581 label: gk956844 - class: variation id: WBVar00501031 label: gk277788 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar00501027 label: gk277784 - class: variation id: WBVar01139447 label: gk483654 - class: variation id: WBVar01139453 label: gk852671 - class: variation id: WBVar01139451 label: gk702636 - class: variation id: WBVar01139454 label: gk906884 - class: variation id: WBVar01139452 label: gk411868 - class: variation id: WBVar01139450 label: gk906450 - class: variation id: WBVar01139433 label: gk931815 - class: variation id: WBVar01139442 label: gk593581 - class: variation id: WBVar01139437 label: gk725708 - class: variation id: WBVar00501032 label: gk277789 - class: variation id: WBVar01139440 label: gk744420 - class: variation id: WBVar01139443 label: gk363729 - class: variation id: WBVar01139436 label: gk501810 - class: variation id: WBVar01139446 label: gk573574 - class: variation id: WBVar01139435 label: gk904279 - class: variation id: WBVar01139434 label: gk884174 - class: variation id: WBVar01139448 label: gk754093 - class: variation id: WBVar00501029 label: gk277786 - class: variation id: WBVar00266587 label: u228 - class: variation id: WBVar01139457 label: gk896389 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable CoA-ligase activity. Involved in detection of mechanical stimulus involved in sensory perception of touch and mechanosensory behavior. Located in neuron projection and neuronal cell body. Expressed in PLML; PLMR; and touch receptor neurons. label: mec-18 legacy_description: mec-18 encodes a protein similar to firefly luciferase and plant protein 4-coumarate coA ligase; mec-18 is involved in sensory mechanotransduction; genetic interactions with other mec genes suggest that mec-18 may be involved in negative regulation of the degenerin channel in the touch receptor neurons; mec-18 is expressed exclusively in the touch cells. merged_into: ~ name: class: gene highlight: description_all: - mec-18 encodes a protein similar to firefly luciferase and plant protein 4-coumarate coA ligase; mec- - 18 is involved in sensory mechanotransduction; genetic interactions with other mec genes suggest that - mec-18 may be involved in negative regulation of the degenerin channel in the touch receptor neurons - ; mec-18 is expressed exclusively in the touch cells. id: WBGene00003179 label: mec-18 other_names: - C52B9.9 - CELE_C52B9.9 - acs-8 - C52B9.9 - C52B9.9.1 - CE16940 taxonomy: c_elegans other_names: - C52B9.9 - CELE_C52B9.9 - acs-8 - C52B9.9 - C52B9.9.1 - CE16940 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003179 - allele: - class: variation id: WBVar00000394 label: b300 - class: variation id: WBVar00249061 label: t1144 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Acts upstream of or within embryo development. label: mel-18 legacy_description: mel-18 was identified in screens for maternal-effect lethal mutations on chromosome II; mel-18 is defined by at least two alleles that result in embryonic lethality, one of which shows very slight zygotic rescue. merged_into: ~ name: class: gene highlight: description_all: - mel-18 was identified in screens for maternal-effect lethal mutations on chromosome II; mel-18 is defined id: WBGene00003203 label: mel-18 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003203 - allele: - class: variation id: WBVar00950912 label: gk510821 - class: variation id: WBVar00950890 label: gk355610 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar02134880 label: h4727 - class: variation id: WBVar00438635 label: gk215392 - class: variation id: WBVar00950913 label: gk811680 - class: variation id: WBVar00950898 label: gk483907 - class: variation id: WBVar00950897 label: gk423024 - class: variation id: WBVar00438632 label: gk215389 - class: variation id: WBVar00091281 label: nj38 - class: variation id: WBVar00950904 label: gk482074 - class: variation id: WBVar00438637 label: gk215394 - class: variation id: WBVar00438638 label: gk215395 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00950892 label: gk830320 - class: variation id: WBVar00950889 label: gk323359 - class: variation id: WBVar00950918 label: gk616184 - class: variation id: WBVar00950917 label: gk598588 - class: variation id: WBVar00950911 label: gk616183 - class: variation id: WBVar00438630 label: gk215387 - class: variation id: WBVar01482527 label: gk946787 - class: variation id: WBVar00950916 label: gk315729 - class: variation id: WBVar00950907 label: gk892345 - class: variation id: WBVar00950899 label: gk813071 - class: variation id: WBVar00950905 label: gk888241 - class: variation id: WBVar00950903 label: gk925960 - class: variation id: WBVar00950884 label: gk355609 - class: variation id: WBVar00950896 label: gk884970 - class: variation id: WBVar01499493 label: gk963547 - class: variation id: WBVar00950891 label: gk423023 - class: variation id: WBVar00950906 label: gk928499 - class: variation id: WBVar00950887 label: gk354935 - class: variation id: WBVar00950910 label: gk510820 - class: variation id: WBVar00438633 label: gk215390 - class: variation id: WBVar00950919 label: gk607123 - class: variation id: WBVar00950883 label: gk772534 - class: variation id: WBVar00438634 label: gk215391 - class: variation id: WBVar00950886 label: gk803198 - class: variation id: WBVar00950895 label: gk489294 - class: variation id: WBVar00950920 label: gk607860 - class: variation id: WBVar00950901 label: gk472757 - class: variation id: WBVar00950908 label: gk737934 - class: variation id: WBVar02134881 label: h17452 - class: variation id: WBVar00950922 label: gk427301 - class: variation id: WBVar00950894 label: gk665065 - class: variation id: WBVar00438636 label: gk215393 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00950921 label: gk525958 - class: variation id: WBVar00950902 label: gk491003 - class: variation id: WBVar00438629 label: gk215386 - class: variation id: WBVar00438631 label: gk215388 - class: variation id: WBVar01499492 label: gk963546 - class: variation id: WBVar00950888 label: gk407422 - class: variation id: WBVar00950885 label: gk370045 - class: variation id: WBVar00950909 label: gk624769 - class: variation id: WBVar00950900 label: gk423025 - class: variation id: WBVar00094132 label: ok3047 - class: variation id: WBVar00950893 label: gk665064 - class: variation id: WBVar00950915 label: gk805785 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00950914 label: gk339788 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in microvillus membrane and neuron projection terminus. Expressed in intestine and nervous system. label: gcy-18 legacy_description: gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, microarray experiments indicate that gcy-18 expression is induced in daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings. merged_into: ~ name: class: gene highlight: description_all: - gcy-18 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-23, constitutes a subfamily - of guanylyl cyclase genes in C. elegans; gcy-18 functions redundantly with gcy-8 and gcy-23, and upstream - daf-16(RNAi); daf-2(RNAi) double mutants and repressed in daf-2(RNAi) mutants, suggesting that GCY-18 - activity may contribute to a shortened lifespan; consistent with this, loss of gcy-18 activity via RNAi - does result in lifespan extension; GCY-18 is expressed exclusively in the AFD thermosensory neurons, id: WBGene00001543 label: gcy-18 other_names: - ZK896.8 - gcy-26 - CELE_ZK896.8 - CE42602 - ZK896.8.1 - ZK896.8 taxonomy: c_elegans other_names: - ZK896.8 - gcy-26 - CELE_ZK896.8 - CE42602 - ZK896.8.1 - ZK896.8 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001543 - allele: - class: variation id: WBVar00261470 label: ttTi33727 - class: variation id: WBVar00493325 label: gk270082 - class: variation id: WBVar01116007 label: gk695898 - class: variation id: WBVar02150133 label: tm12551 - class: variation id: WBVar00493332 label: gk270089 - class: variation id: WBVar00493326 label: gk270083 - class: variation id: WBVar01116000 label: gk370676 - class: variation id: WBVar01116019 label: gk805434 - class: variation id: WBVar00493324 label: gk270081 - class: variation id: WBVar01116002 label: gk684951 - class: variation id: WBVar01116016 label: gk755649 - class: variation id: WBVar01116020 label: gk680672 - class: variation id: WBVar01116036 label: gk917989 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar01116017 label: gk356613 - class: variation id: WBVar01116015 label: gk828667 - class: variation id: WBVar01116034 label: gk919962 - class: variation id: WBVar00493333 label: gk270090 - class: variation id: WBVar01116037 label: gk404507 - class: variation id: WBVar00256506 label: ttTi11106 - class: variation id: WBVar01499773 label: gk963886 - class: variation id: WBVar01116021 label: gk901380 - class: variation id: WBVar01116008 label: gk447946 - class: variation id: WBVar01116001 label: gk883082 - class: variation id: WBVar01116028 label: gk335289 - class: variation id: WBVar01116011 label: gk348759 - class: variation id: WBVar00307132 label: otn10311 - class: variation id: WBVar01116029 label: gk796741 - class: variation id: WBVar00144598 label: e2150 - class: variation id: WBVar01116027 label: gk765540 - class: variation id: WBVar01116039 label: gk543362 - class: variation id: WBVar00275201 label: wx74 - class: variation id: WBVar00493329 label: gk270086 - class: variation id: WBVar01499772 label: gk963885 - class: variation id: WBVar01116025 label: gk524434 - class: variation id: WBVar01116026 label: gk722419 - class: variation id: WBVar01116035 label: gk575337 - class: variation id: WBVar01116031 label: gk460680 - class: variation id: WBVar01116032 label: gk322450 - class: variation id: WBVar01116038 label: gk860249 - class: variation id: WBVar00493323 label: gk270080 - class: variation id: WBVar01116009 label: gk652143 - class: variation id: WBVar01116005 label: gk557368 - class: variation id: WBVar01116012 label: gk348760 - class: variation id: WBVar01116010 label: gk743131 - class: variation id: WBVar00493328 label: gk270085 - class: variation id: WBVar02138635 label: h14270 - class: variation id: WBVar01116014 label: gk631911 - class: variation id: WBVar01498638 label: gk963652 - class: variation id: WBVar00493330 label: gk270087 - class: variation id: WBVar00493331 label: gk270088 - class: variation id: WBVar01116013 label: gk542766 - class: variation id: WBVar00493327 label: gk270084 - class: variation id: WBVar01116004 label: gk883083 - class: variation id: WBVar00275202 label: wx75 - class: variation id: WBVar00144142 label: e1599 - class: variation id: WBVar01115998 label: gk574611 - class: variation id: WBVar01116030 label: gk537051 - class: variation id: WBVar01116024 label: gk414337 - class: variation id: WBVar01116033 label: gk368238 - class: variation id: WBVar01116023 label: gk582056 - class: variation id: WBVar01116003 label: gk729190 - class: variation id: WBVar01115999 label: gk504465 - class: variation id: WBVar01116022 label: gk774193 - class: variation id: WBVar01116006 label: gk503026 - class: variation id: WBVar00493334 label: gk270091 - class: variation id: WBVar00493335 label: gk270092 - class: variation id: WBVar01116018 label: gk734561 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in plasma membrane. Expressed in PQR; hypodermis; and vulva. label: mab-7 legacy_description: mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically affecting the structural cells, neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab-7 promoter-gfp construct is expressed in hypodermis, body seam, ray structural cells, and several neurons in the head and tail region. merged_into: ~ name: class: gene highlight: description_all: - mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like - motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically - neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab id: WBGene00003104 label: mab-7 other_names: - ZC13.4 - CELE_ZC13.4 - ZC13.4.1 - CE41485 - ZC13.4 taxonomy: c_elegans other_names: - ZC13.4 - CELE_ZC13.4 - ZC13.4.1 - CE41485 - ZC13.4 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003104 - allele: - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00948889 label: gk343072 - class: variation id: WBVar01498811 label: gk964475 - class: variation id: WBVar00437970 label: gk214727 - class: variation id: WBVar00948899 label: gk756890 - class: variation id: WBVar00948891 label: gk652691 - class: variation id: WBVar00948898 label: gk885940 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar00437971 label: gk214728 - class: variation id: WBVar00437969 label: gk214726 - class: variation id: WBVar00437968 label: gk214725 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00948892 label: gk774020 - class: variation id: WBVar00948890 label: gk722922 - class: variation id: WBVar00948897 label: gk866165 - class: variation id: WBVar00948886 label: gk858694 - class: variation id: WBVar00948893 label: gk629827 - class: variation id: WBVar00948887 label: gk869057 - class: variation id: WBVar00948896 label: gk541778 - class: variation id: WBVar00948888 label: gk706072 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00948895 label: gk621470 - class: variation id: WBVar01498982 label: gk962743 - class: variation id: WBVar00948894 label: gk674618 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-16; daf-18; and atfs-1 based on RNA-seq studies. label: F53B2.7 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; daf-18; and atfs-1 based on RNA-seq studies. id: WBGene00014769 label: F53B2.7 other_names: - F53B2.7 - CELE_F53B2.7 - F53B2.7 taxonomy: c_elegans other_names: - F53B2.7 - CELE_F53B2.7 - F53B2.7 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00014769 - allele: - class: variation id: WBVar00614983 label: gk573170 - class: variation id: WBVar00326701 label: gk103458 - class: variation id: WBVar00614948 label: gk650125 - class: variation id: WBVar00326716 label: gk103473 - class: variation id: WBVar00326708 label: gk103465 - class: variation id: WBVar00614997 label: gk573625 - class: variation id: WBVar00614966 label: gk745669 - class: variation id: WBVar00326703 label: gk103460 - class: variation id: WBVar00326717 label: gk103474 - class: variation id: WBVar02126359 label: h13140 - class: variation id: WBVar01499321 label: gk963316 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar01474841 label: gk939095 - class: variation id: WBVar00614973 label: gk346585 - class: variation id: WBVar00614978 label: gk621729 - class: variation id: WBVar00326700 label: gk103457 - class: variation id: WBVar00143511 label: e819 - class: variation id: WBVar00614954 label: gk379822 - class: variation id: WBVar00615005 label: gk917714 - class: variation id: WBVar01499559 label: gk963630 - class: variation id: WBVar00326715 label: gk103472 - class: variation id: WBVar00145253 label: ev574 - class: variation id: WBVar00614984 label: gk916836 - class: variation id: WBVar00614960 label: gk821505 - class: variation id: WBVar00614999 label: gk897570 - class: variation id: WBVar00614982 label: gk641634 - class: variation id: WBVar00614974 label: gk650818 - class: variation id: WBVar00614986 label: gk876533 - class: variation id: WBVar00614993 label: gk837899 - class: variation id: WBVar00614975 label: gk365858 - class: variation id: WBVar00326709 label: gk103466 - class: variation id: WBVar00255016 label: ttTi6066 - class: variation id: WBVar00145289 label: ev778 - class: variation id: WBVar00326714 label: gk103471 - class: variation id: WBVar00614949 label: gk550831 - class: variation id: WBVar00614977 label: gk442860 - class: variation id: WBVar00614994 label: gk767886 - class: variation id: WBVar00614995 label: gk517849 - class: variation id: WBVar00614996 label: gk873777 - class: variation id: WBVar00614956 label: gk574776 - class: variation id: WBVar01499619 label: gk963701 - class: variation id: WBVar02153652 label: gk5250 - class: variation id: WBVar00614991 label: gk678240 - class: variation id: WBVar00615004 label: gk926162 - class: variation id: WBVar01474844 label: gk939098 - class: variation id: WBVar01474846 label: gk939100 - class: variation id: WBVar00614998 label: gk674247 - class: variation id: WBVar00326712 label: gk103469 - class: variation id: WBVar00614969 label: gk325526 - class: variation id: WBVar00614970 label: gk536662 - class: variation id: WBVar00326702 label: gk103459 - class: variation id: WBVar01474843 label: gk939097 - class: variation id: WBVar00326706 label: gk103463 - class: variation id: WBVar00614967 label: gk343881 - class: variation id: WBVar00614950 label: gk558999 - class: variation id: WBVar00614958 label: gk347964 - class: variation id: WBVar00000566 label: bx24 - class: variation id: WBVar00614952 label: gk839217 - class: variation id: WBVar02126360 label: h7916 - class: variation id: WBVar00614959 label: gk458429 - class: variation id: WBVar00614990 label: gk564954 - class: variation id: WBVar00615006 label: gk881196 - class: variation id: WBVar00615000 label: gk856662 - class: variation id: WBVar00614976 label: gk428747 - class: variation id: WBVar00253188 label: ttTi366 - class: variation id: WBVar00614980 label: gk730603 - class: variation id: WBVar00326698 label: gk103455 - class: variation id: WBVar00614989 label: gk729342 - class: variation id: WBVar00615002 label: gk356702 - class: variation id: WBVar00614955 label: gk911503 - class: variation id: WBVar00326705 label: gk103462 - class: variation id: WBVar00326710 label: gk103467 - class: variation id: WBVar01474842 label: gk939096 - class: variation id: WBVar00614961 label: gk699099 - class: variation id: WBVar00326718 label: gk103475 - class: variation id: WBVar00614953 label: gk473396 - class: variation id: WBVar00326704 label: gk103461 - class: variation id: WBVar01474845 label: gk939099 - class: variation id: WBVar00614981 label: gk419394 - class: variation id: WBVar00614963 label: gk763018 - class: variation id: WBVar00326719 label: gk103476 - class: variation id: WBVar00614987 label: gk663759 - class: variation id: WBVar00614951 label: gk534486 - class: variation id: WBVar00614979 label: gk456987 - class: variation id: WBVar00614957 label: gk805570 - class: variation id: WBVar00326711 label: gk103468 - class: variation id: WBVar00615003 label: gk802496 - class: variation id: WBVar00614965 label: gk825598 - class: variation id: WBVar00614972 label: gk468596 - class: variation id: WBVar00615001 label: gk590758 - class: variation id: WBVar00326707 label: gk103464 - class: variation id: WBVar01499323 label: gk963318 - class: variation id: WBVar00614985 label: gk352254 - class: variation id: WBVar00614988 label: gk911504 - class: variation id: WBVar00614971 label: gk401509 - class: variation id: WBVar00614968 label: gk916117 - class: variation id: WBVar00326713 label: gk103470 - class: variation id: WBVar00615007 label: gk928875 - class: variation id: WBVar00326699 label: gk103456 - class: variation id: WBVar00614964 label: gk537123 - class: variation id: WBVar00614962 label: gk470150 - class: variation id: WBVar00000587 label: bx61 - class: variation id: WBVar00614992 label: gk877118 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables semaphorin receptor binding activity. Involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. Located in cell surface. Expressed in several structures, including linker cell; ray neurons; ray precursor cell; somatic nervous system; and vulval cell. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Is an ortholog of human SEMA3B (semaphorin 3B) and SEMA3C (semaphorin 3C). label: mab-20 legacy_description: mab-20 encodes the C. elegans Semaphorin-2A ortholog; during development, mab-20 activity is required for proper epidermal morphogenesis and axon guidance; specifically, MAB-20, which functions to prevent ectopic, adhesive cell contacts, is required for ventral enclosure during embryogenesis, normal body morphology, and proper formation of sensory rays in the male tail; co-immunoprecipitation experiments demonstrate that MAB-20 interacts with the PLX-2 receptor and that this interaction is strengthened by LAD-2 which can interact with both proteins independently; a MAB-20::GFP reporter, which localizes to the cell surface, is expressed ubiquitously in embryos beginning at morphogenesis; in larvae and adults, MAB-20::GFP is seen in dividing seam cells, neurons, vulval cells, the distal tip cell in hermaphrodites and in males, is additionally seen in the linker cell, cells in the posterior ganglia, and the 9 R(n) ray precursor cells. merged_into: ~ name: class: gene highlight: description_all: - mab-20 encodes the C. elegans Semaphorin-2A ortholog; during development, mab-20 activity is required - for proper epidermal morphogenesis and axon guidance; specifically, MAB-20, which functions to prevent - proper formation of sensory rays in the male tail; co-immunoprecipitation experiments demonstrate that MAB - that this interaction is strengthened by LAD-2 which can interact with both proteins independently; a MAB - cell surface, is expressed ubiquitously in embryos beginning at morphogenesis; in larvae and adults, MAB id: WBGene00003111 label: mab-20 other_names: - Y71G12B.20 - CELE_Y71G12B.20 - Y71G12B.20b - Y71G12B.20c - Y71G12B.20c.1 - Y71G12B.20d - CE49604 - Y71G12B.20d.1 - CE49534 - Y71G12B.20a.1 - Y71G12B.20a - CE22926 taxonomy: c_elegans other_names: - Y71G12B.20 - CELE_Y71G12B.20 - Y71G12B.20b - Y71G12B.20c - Y71G12B.20c.1 - Y71G12B.20d - CE49604 - Y71G12B.20d.1 - CE49534 - Y71G12B.20a.1 - Y71G12B.20a - CE22926 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003111 - allele: - class: variation id: WBVar01497108 label: gk961371 - class: variation id: WBVar01171254 label: gk850329 - class: variation id: WBVar01487382 label: gk951644 - class: variation id: WBVar00054217 label: cn110 - class: variation id: WBVar02152470 label: tm12200 - class: variation id: WBVar00511871 label: gk288628 - class: variation id: WBVar01171265 label: gk885678 - class: variation id: WBVar01171257 label: gk379138 - class: variation id: WBVar01171255 label: gk908878 - class: variation id: WBVar00511869 label: gk288626 - class: variation id: WBVar01171256 label: gk908879 - class: variation id: WBVar01499963 label: gk964126 - class: variation id: WBVar00511868 label: gk288625 - class: variation id: WBVar01171249 label: gk757765 - class: variation id: WBVar01171250 label: gk450234 - class: variation id: WBVar02139782 label: h12521 - class: variation id: WBVar01171266 label: gk676677 - class: variation id: WBVar01171246 label: gk447345 - class: variation id: WBVar00144388 label: e1913 - class: variation id: WBVar01171258 label: gk710814 - class: variation id: WBVar01171253 label: gk848115 - class: variation id: WBVar01171259 label: gk353017 - class: variation id: WBVar01171252 label: gk595380 - class: variation id: WBVar01171263 label: gk894313 - class: variation id: WBVar01498722 label: gk964112 - class: variation id: WBVar01171264 label: gk422558 - class: variation id: WBVar01171245 label: gk489891 - class: variation id: WBVar01171262 label: gk695072 - class: variation id: WBVar00242598 label: sa589 - class: variation id: WBVar01171248 label: gk572348 - class: variation id: WBVar01171261 label: gk479651 - class: variation id: WBVar01499642 label: gk963732 - class: variation id: WBVar00511866 label: gk288623 - class: variation id: WBVar00511867 label: gk288624 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar00511865 label: gk288622 - class: variation id: WBVar00511870 label: gk288627 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01171267 label: gk344853 - class: variation id: WBVar00144794 label: e2383 - class: variation id: WBVar01171247 label: gk449537 - class: variation id: WBVar02148396 label: bln213 - class: variation id: WBVar00144389 label: e1913e2383 - class: variation id: WBVar01171251 label: gk584741 - class: variation id: WBVar00511872 label: gk288629 - class: variation id: WBVar01171260 label: gk879392 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables outward rectifier potassium channel activity. Involved in locomotion; muscle contraction; and potassium ion transport. Predicted to be located in membrane. Expressed in body wall musculature. label: twk-18 legacy_description: twk-18 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; TWK-18 was originally defined by gain-of-function mutations that result in embryonic lethality at the two-fold stage, locomotion defects, longer than normal body length, abnormal egg-laying, and temperature-sensitive paralysis; as loss of TWK-18 function via reversion or RNA-mediated interference does not result in any abnormalities, TWK-18 likely functions redundantly with other TWK channels; TWK-18 can function as an outwardly rectifying K+ channel, and is activated by temperature increases, thus making it a temperature-gated channel; TWK-18 is expressed in body wall muscle. merged_into: ~ name: class: gene highlight: description_all: - twk-18 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two - pore-forming domains and four transmembrane domains; TWK-18 was originally defined by gain-of-function - longer than normal body length, abnormal egg-laying, and temperature-sensitive paralysis; as loss of TWK-18 - function via reversion or RNA-mediated interference does not result in any abnormalities, TWK-18 likely - functions redundantly with other TWK channels; TWK-18 can function as an outwardly rectifying K+ channel id: WBGene00006672 label: twk-18 other_names: - C24A3.6 - twk-2 - CELE_C24A3.6 - mah-2 - unc-110 - C24A3.6 - CE24811 - C24A3.6.1 - C24A3.6.2 taxonomy: c_elegans other_names: - C24A3.6 - twk-2 - CELE_C24A3.6 - mah-2 - unc-110 - C24A3.6 - CE24811 - C24A3.6.1 - C24A3.6.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006672 - allele: - class: variation id: WBVar00088361 label: ku354 - class: variation id: WBVar00837252 label: gk701763 - class: variation id: WBVar00837251 label: gk884850 - class: variation id: WBVar00600823 label: tm5426 - class: variation id: WBVar01499433 label: gk963469 - class: variation id: WBVar00604207 label: ku254 - class: variation id: WBVar00401003 label: gk177760 - class: variation id: WBVar00837249 label: gk817467 - class: variation id: WBVar00837254 label: gk659192 - class: variation id: WBVar00837253 label: gk380983 - class: variation id: WBVar01500260 label: gk964518 - class: variation id: WBVar00837250 label: gk393672 - class: variation id: WBVar01499774 label: gk963887 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase binding activity. Involved in determination of adult lifespan; embryonic digestive tract morphogenesis; and protein metabolic process. Acts upstream of or within animal organ morphogenesis. Predicted to be located in nucleus. Predicted to be part of ubiquitin ligase complex. Is an ortholog of human UBE2L3 (ubiquitin conjugating enzyme E2 L3) and UBE2L5 (ubiquitin conjugating enzyme E2 L5). label: ubc-18 legacy_description: ubc-18 encodes an E2 ubiquitin-conjugating enzyme related to human UBCH7 (OMIM:603731); UBC-18 activity is required for normal growth and reproduction, and UBC-18 functions redundantly with LIN-35/Rb and other class B synthetic multivulval (SynMuv) gene products to regulate pharyngeal morphogenesis during embryonic development; ubc-18 transcripts are detected in the germline, embryos, late larval stages, and adults, suggesting that UBC-18 may function maternally to regulate several aspects of C. elegans development; the substrates of UBC-18 are not yet known. merged_into: ~ name: class: gene highlight: description_all: - ubc-18 encodes an E2 ubiquitin-conjugating enzyme related to human UBCH7 (OMIM:603731); UBC-18 activity - is required for normal growth and reproduction, and UBC-18 functions redundantly with LIN-35/Rb and - multivulval (SynMuv) gene products to regulate pharyngeal morphogenesis during embryonic development; ubc-18 - transcripts are detected in the germline, embryos, late larval stages, and adults, suggesting that UBC-18 - may function maternally to regulate several aspects of C. elegans development; the substrates of UBC-18 id: WBGene00006713 label: ubc-18 other_names: - R01H2.6 - CELE_R01H2.6 - CE25067 - R01H2.6.1 - R01H2.6 taxonomy: c_elegans other_names: - R01H2.6 - CELE_R01H2.6 - CE25067 - R01H2.6.1 - R01H2.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006713 - allele: - class: variation id: WBVar00000085 label: ad1110 - class: variation id: WBVar00691631 label: gk548965 - class: variation id: WBVar00691630 label: gk547306 - class: variation id: WBVar00691637 label: gk315925 - class: variation id: WBVar00088271 label: kr26 - class: variation id: WBVar00691583 label: gk676198 - class: variation id: WBVar00352440 label: gk129197 - class: variation id: WBVar00691600 label: gk374669 - class: variation id: WBVar00352439 label: gk129196 - class: variation id: WBVar00691584 label: gk884378 - class: variation id: WBVar00352445 label: gk129202 - class: variation id: WBVar00691613 label: gk799711 - class: variation id: WBVar00691601 label: gk328627 - class: variation id: WBVar00691590 label: gk523562 - class: variation id: WBVar00352430 label: gk129187 - class: variation id: WBVar00352424 label: gk129181 - class: variation id: WBVar00691617 label: gk414784 - class: variation id: WBVar00691612 label: gk863770 - class: variation id: WBVar00691618 label: gk327764 - class: variation id: WBVar00691589 label: gk497978 - class: variation id: WBVar00691656 label: gk351412 - class: variation id: WBVar00691591 label: gk539226 - class: variation id: WBVar00691635 label: gk530533 - class: variation id: WBVar00691607 label: gk411985 - class: variation id: WBVar00691634 label: gk749735 - class: variation id: WBVar00691644 label: gk349392 - class: variation id: WBVar00352441 label: gk129198 - class: variation id: WBVar00303996 label: otn7175 - class: variation id: WBVar00691633 label: gk513065 - class: variation id: WBVar00691628 label: gk675696 - class: variation id: WBVar02129064 label: h7546 - class: variation id: WBVar00691650 label: gk791548 - class: variation id: WBVar00352434 label: gk129191 - class: variation id: WBVar00352435 label: gk129192 - class: variation id: WBVar01493321 label: gk957584 - class: variation id: WBVar00352444 label: gk129201 - class: variation id: WBVar00691595 label: gk539227 - class: variation id: WBVar00691599 label: gk409233 - class: variation id: WBVar00691605 label: gk584369 - class: variation id: WBVar00691645 label: gk582843 - class: variation id: WBVar00068239 label: cxTi7118 - class: variation id: WBVar00352438 label: gk129195 - class: variation id: WBVar00352448 label: gk129205 - class: variation id: WBVar00691651 label: gk715102 - class: variation id: WBVar00352432 label: gk129189 - class: variation id: WBVar00691598 label: gk620439 - class: variation id: WBVar00691625 label: gk412926 - class: variation id: WBVar00254049 label: ttTi3366 - class: variation id: WBVar00691610 label: gk827209 - class: variation id: WBVar00691620 label: gk765681 - class: variation id: WBVar00691619 label: gk376044 - class: variation id: WBVar00691639 label: gk743891 - class: variation id: WBVar00352442 label: gk129199 - class: variation id: WBVar01490402 label: gk954665 - class: variation id: WBVar00691609 label: gk412612 - class: variation id: WBVar00092415 label: ok1154 - class: variation id: WBVar00691593 label: gk353139 - class: variation id: WBVar00691632 label: gk788802 - class: variation id: WBVar02148335 label: tm10595 - class: variation id: WBVar00352433 label: gk129190 - class: variation id: WBVar00691654 label: gk719585 - class: variation id: WBVar00691622 label: gk662134 - class: variation id: WBVar01498939 label: gk962681 - class: variation id: WBVar00691640 label: gk815278 - class: variation id: WBVar00352437 label: gk129194 - class: variation id: WBVar00691646 label: gk636031 - class: variation id: WBVar00093294 label: ok2111 - class: variation id: WBVar00352428 label: gk129185 - class: variation id: WBVar00691648 label: gk787741 - class: variation id: WBVar00691653 label: gk687010 - class: variation id: WBVar00691641 label: gk618146 - class: variation id: WBVar00352446 label: gk129203 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00352436 label: gk129193 - class: variation id: WBVar00352426 label: gk129183 - class: variation id: WBVar00691615 label: gk567580 - class: variation id: WBVar00352427 label: gk129184 - class: variation id: WBVar00352431 label: gk129188 - class: variation id: WBVar00691643 label: gk899352 - class: variation id: WBVar01495049 label: gk959312 - class: variation id: WBVar00691626 label: gk613621 - class: variation id: WBVar00691586 label: gk489990 - class: variation id: WBVar00691624 label: gk830709 - class: variation id: WBVar00691597 label: gk564457 - class: variation id: WBVar00070134 label: cxTi8924 - class: variation id: WBVar00691588 label: gk928164 - class: variation id: WBVar00691638 label: gk561066 - class: variation id: WBVar00691594 label: gk809630 - class: variation id: WBVar00691636 label: gk315618 - class: variation id: WBVar00691606 label: gk356223 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar00691602 label: gk791547 - class: variation id: WBVar00691655 label: gk719586 - class: variation id: WBVar00691604 label: gk413261 - class: variation id: WBVar00691623 label: gk703833 - class: variation id: WBVar00352449 label: gk129206 - class: variation id: WBVar00091418 label: nu209 - class: variation id: WBVar00691627 label: gk682107 - class: variation id: WBVar00691608 label: gk687911 - class: variation id: WBVar00000071 label: ad820 - class: variation id: WBVar00691649 label: gk447413 - class: variation id: WBVar00691585 label: gk796903 - class: variation id: WBVar00691596 label: gk347255 - class: variation id: WBVar00691657 label: gk362226 - class: variation id: WBVar00691614 label: gk412397 - class: variation id: WBVar00691652 label: gk578063 - class: variation id: WBVar00691592 label: gk634635 - class: variation id: WBVar00691621 label: gk670255 - class: variation id: WBVar00352447 label: gk129204 - class: variation id: WBVar00691603 label: gk595497 - class: variation id: WBVar00691647 label: gk920675 - class: variation id: WBVar00691642 label: gk835451 - class: variation id: WBVar00352429 label: gk129186 - class: variation id: WBVar00352443 label: gk129200 - class: variation id: WBVar00691587 label: gk691735 - class: variation id: WBVar01499823 label: gk963947 - class: variation id: WBVar00352425 label: gk129182 - class: variation id: WBVar00352423 label: gk129180 - class: variation id: WBVar00691629 label: gk788801 - class: variation id: WBVar00691616 label: gk849850 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Involved in chemical synaptic transmission and regulation of pharyngeal pumping. Predicted to be located in membrane. label: eat-18 legacy_description: eat-18 encodes a small novel protein with an intracellular N terminus, a single predicted transmembrane domain, and a short, extracellular carboxy terminus; eat-18 is required for proper nicotinic neurotransmission by the excitatory pharyngeal MC neuron and thus, for rapid pharyngeal pumping in the presence of food; eat-18 is also required for alpha-bungarotoxin-binding to pharyngeal nicotinic receptors, suggesting that EAT-18 is required for normal topology of most or all nicotinic receptors in postsynaptic cells in the pharynx; an EAT-18::GFP fusion protein is expressed in pharyngeal muscle, the M5 pharyngeal motor neuron, and five to six unidentified extrapharyngeal neurons; eat-18 displays allele-specific genetic interactions with eat-2, which encodes a non-alpha-nicotonic acetylcholine receptor subunit expressed in pharyngeal muscle and also required for proper regulation of the pharyngeal pumping rate. merged_into: ~ name: class: gene highlight: description_all: - eat-18 encodes a small novel protein with an intracellular N terminus, a single predicted transmembrane - domain, and a short, extracellular carboxy terminus; eat-18 is required for proper nicotinic neurotransmission - excitatory pharyngeal MC neuron and thus, for rapid pharyngeal pumping in the presence of food; eat-18 - also required for alpha-bungarotoxin-binding to pharyngeal nicotinic receptors, suggesting that EAT-18 - for normal topology of most or all nicotinic receptors in postsynaptic cells in the pharynx; an EAT-18 id: WBGene00001147 label: eat-18 other_names: - Y105E8A.7 - CELE_EAT-18 - Y105E8A.7c.1 - Y105E8A.7d - Y105E8A.7d.1 - CE33723 - Y105E8A.7d.3 - Y105E8A.7c - Y105E8A.7d.2 - CE37055 taxonomy: c_elegans other_names: - Y105E8A.7 - CELE_EAT-18 - Y105E8A.7c.1 - Y105E8A.7d - Y105E8A.7d.1 - CE33723 - Y105E8A.7d.3 - Y105E8A.7c - Y105E8A.7d.2 - CE37055 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001147 - allele: - class: variation id: WBVar00251665 label: tm2841 - class: variation id: WBVar00919182 label: gk841768 - class: variation id: WBVar00427976 label: gk204733 - class: variation id: WBVar00919189 label: gk366040 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00427969 label: gk204726 - class: variation id: WBVar00919179 label: gk920889 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar01499395 label: gk963416 - class: variation id: WBVar02157142 label: or392 - class: variation id: WBVar00919177 label: gk353269 - class: variation id: WBVar00919188 label: gk899496 - class: variation id: WBVar00427975 label: gk204732 - class: variation id: WBVar00919181 label: gk735887 - class: variation id: WBVar02134111 label: h14212 - class: variation id: WBVar00919175 label: gk652639 - class: variation id: WBVar00093655 label: ok2519 - class: variation id: WBVar01489077 label: gk953340 - class: variation id: WBVar00427971 label: gk204728 - class: variation id: WBVar00919186 label: gk401045 - class: variation id: WBVar00919185 label: gk928447 - class: variation id: WBVar00919184 label: gk544524 - class: variation id: WBVar02157164 label: or870 - class: variation id: WBVar00427972 label: gk204729 - class: variation id: WBVar00427973 label: gk204730 - class: variation id: WBVar00251967 label: tm3211 - class: variation id: WBVar00427968 label: gk204725 - class: variation id: WBVar00919183 label: gk720610 - class: variation id: WBVar00427977 label: gk204734 - class: variation id: WBVar00919176 label: gk524719 - class: variation id: WBVar00919180 label: gk804311 - class: variation id: WBVar00919192 label: gk608657 - class: variation id: WBVar01491900 label: gk956163 - class: variation id: WBVar00919190 label: gk595137 - class: variation id: WBVar00427970 label: gk204727 - class: variation id: WBVar00427974 label: gk204731 - class: variation id: WBVar00919178 label: gk608656 - class: variation id: WBVar00919187 label: gk527232 - class: variation id: WBVar00919191 label: gk692492 - class: variation id: WBVar01499396 label: gk963417 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP hydrolysis activity; microtubule binding activity; and microtubule motor activity. Involved in meiotic spindle assembly. Located in cell cortex; microtubule; and spindle pole. Expressed in Z2; Z3; and germ line. Is an ortholog of human KIF15 (kinesin family member 15). label: klp-18 legacy_description: "klp-18 encodes a kinesin motor protein whose motor domain is most similar to that of the Xenopus and human klp2 proteins; loss of klp-18 activity via RNAi indicates that KLP-18 is required for the assembly of a disordered array of acentrosomal (female meiotic) microtubules into an organized, functional, bipolar spindle; in addition, KLP-18 may also play a role in cortex dynamics during post-meiotic development; antibody staining indicates that during meiosis and mitosis (early embryonic) KLP-18 localizes to: 1) spindles, and especially spindle poles, during prometaphase, metaphase, and early anaphase, and 2) the interzone during late anaphase and telophase; in early embryos, KLP-18 is also seen around the nucleus and cell cortex at sites of cell-cell contact; KLP-18 expression in later embryos and larvae is confined to the germ line which, in adults, stains brightly in both distal and proximal regions." merged_into: ~ name: class: gene highlight: description_all: - klp-18 encodes a kinesin motor protein whose motor domain is most similar to that of the Xenopus and - human klp2 proteins; loss of klp-18 activity via RNAi indicates that KLP-18 is required for the assembly - acentrosomal (female meiotic) microtubules into an organized, functional, bipolar spindle; in addition, KLP-18 - and early anaphase, and 2) the interzone during late anaphase and telophase; in early embryos, KLP-18 - is also seen around the nucleus and cell cortex at sites of cell-cell contact; KLP-18 expression in id: WBGene00002228 label: klp-18 other_names: - C06G3.2 - CELE_C06G3.2 - CE07978 - C06G3.2 - C06G3.2.1 taxonomy: c_elegans other_names: - C06G3.2 - CELE_C06G3.2 - CE07978 - C06G3.2 - C06G3.2.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00002228 - allele: - class: variation id: WBVar01500208 label: gk964451 - class: variation id: WBVar01048517 label: gk745978 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01500209 label: gk964452 - class: variation id: WBVar00094246 label: ok3173 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar00470594 label: gk247351 - class: variation id: WBVar01500058 label: gk964250 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable metalloendopeptidase activity. Predicted to be involved in molting cycle and proteolysis. Predicted to be located in extracellular region. label: nas-18 legacy_description: nas-18 encodes an astacin-like metalloprotease; loss of nas-18 activity via RNAi results in a reduction of fat content suggesting an abnormality in lipid metabolism. merged_into: ~ name: class: gene highlight: description_all: - nas-18 encodes an astacin-like metalloprotease; loss of nas-18 activity via RNAi results in a reduction id: WBGene00003537 label: nas-18 other_names: - K03B8.3 - CELE_K03B8.3 - CE51528 - K03B8.3 - K03B8.3.1 taxonomy: c_elegans other_names: - K03B8.3 - CELE_K03B8.3 - CE51528 - K03B8.3 - K03B8.3.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003537 - allele: - class: variation id: WBVar00652893 label: gk843792 - class: variation id: WBVar00652890 label: gk489494 - class: variation id: WBVar01498288 label: gk962622 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00652889 label: gk728854 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar01500105 label: gk964316 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar02144782 label: tm7135 - class: variation id: WBVar00652892 label: gk651508 - class: variation id: WBVar00339356 label: gk116113 - class: variation id: WBVar00652891 label: gk516677 - class: variation id: WBVar00092823 label: ok1615 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of human ASMTL (acetylserotonin O-methyltransferase like). label: dod-18 legacy_description: dod-18 encodes a Maf-like protein required for normally short lifespan;dod-18 is repressed in daf-2 mutants and induced in daf-16 mutants, anddod-18(RNAi) lengthens lifespan by 30%; MAF-like proteins are ubiquitousamong eukarya, bacteria, and archaea; DOD-18 is orthologous to theN-terminal ~200 residues of human ASMTL (OMIM:300162), and to Bacillussubtilis Maf (Multicopy Associated Filamentation) protein, whichinhibits septum formation; while the specific biochemical function ofMaf-like proteins is unknown, the tertiary structure of B. subtilis Mafis consistent with its binding nucleic acid. merged_into: ~ name: class: gene highlight: description_all: - dod-18 encodes a Maf-like protein required for normally short lifespan;dod-18 is repressed in daf-2 mutants - and induced in daf-16 mutants, anddod-18(RNAi) lengthens lifespan by 30%; MAF-like proteins are ubiquitousamong - eukarya, bacteria, and archaea; DOD-18 is orthologous to theN-terminal ~200 residues of human ASMTL id: WBGene00008316 label: dod-18 other_names: - C54G4.6 - CELE_C54G4.6 - CE42082 - C54G4.6.1 - C54G4.6 taxonomy: c_elegans other_names: - C54G4.6 - CELE_C54G4.6 - CE42082 - C54G4.6.1 - C54G4.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00008316 - allele: - class: variation id: WBVar01030886 label: gk617930 - class: variation id: WBVar01030887 label: gk555786 - class: variation id: WBVar00464605 label: gk241362 - class: variation id: WBVar01030891 label: gk918579 - class: variation id: WBVar00464603 label: gk241360 - class: variation id: WBVar01030882 label: gk811001 - class: variation id: WBVar01030889 label: gk467276 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01030890 label: gk719866 - class: variation id: WBVar00464607 label: gk241364 - class: variation id: WBVar01030888 label: gk554800 - class: variation id: WBVar01030885 label: gk727511 - class: variation id: WBVar01030884 label: gk563176 - class: variation id: WBVar00464604 label: gk241361 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01030883 label: gk923883 - class: variation id: WBVar00464606 label: gk241363 - class: variation id: WBVar01484373 label: gk948633 - class: variation id: WBVar01499056 label: gk962860 - class: variation id: WBVar01499903 label: gk964052 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to be part of vacuolar proton-transporting V-type ATPase, V1 domain. Is an ortholog of human ATP6V1H (ATPase H+ transporting V1 subunit H). label: vha-18 legacy_description: vha-18 encodes an an ortholog of subunit H of the cytoplasmic (V1)domain of vacuolar proton-translocating ATPase (V-ATPase); VHA-18 andVHA-15 are co-orthologs; VHA-18 is a predicted cytosolic stator(stalk) component. merged_into: ~ name: class: gene highlight: description_all: - vha-18 encodes an an ortholog of subunit H of the cytoplasmic (V1)domain of vacuolar proton-translocating - ATPase (V-ATPase); VHA-18 andVHA-15 are co-orthologs; VHA-18 is a predicted cytosolic stator(stalk) id: WBGene00018698 label: vha-18 other_names: - F52E1.10 - CELE_F52E1.10 - F52E1.10 - F52E1.10.1 - CE04638 taxonomy: c_elegans other_names: - F52E1.10 - CELE_F52E1.10 - F52E1.10 - F52E1.10.1 - CE04638 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00018698 - allele: - class: variation id: WBVar01499493 label: gk963547 - class: variation id: WBVar00302103 label: otn5282 - class: variation id: WBVar00955070 label: gk788576 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00955065 label: gk554255 - class: variation id: WBVar00955066 label: gk752115 - class: variation id: WBVar01499492 label: gk963546 - class: variation id: WBVar00955069 label: gk931033 - class: variation id: WBVar00955063 label: gk790883 - class: variation id: WBVar00955067 label: gk610400 - class: variation id: WBVar00955071 label: gk730294 - class: variation id: WBVar00251033 label: tm2093 - class: variation id: WBVar00955068 label: gk520525 - class: variation id: WBVar00955064 label: gk354395 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar01499952 label: gk964111 - class: variation id: WBVar00955062 label: gk815480 - class: variation id: WBVar01499951 label: gk964110 - class: variation id: WBVar01500245 label: gk964500 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of human TSPAN1 (tetraspanin 1); TSPAN18 (tetraspanin 18); and TSPAN4 (tetraspanin 4). label: tsp-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human TSPAN1 (tetraspanin 1); TSPAN18 (tetraspanin 18); and TSPAN4 (tetraspanin 4). id: WBGene00006631 label: tsp-5 other_names: - Y45F10B.1 - CELE_Y45F10B.1 - CE35665 - Y45F10B.1 - Y45F10B.1.1 taxonomy: c_elegans other_names: - Y45F10B.1 - CELE_Y45F10B.1 - CE35665 - Y45F10B.1 - Y45F10B.1.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006631 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: col-18 legacy_description: col-18 encodes a predicted collagen protein; mRNA is expressed during L2 to dauer and L4 to adult larval stage molts. merged_into: ~ name: class: gene highlight: description_all: - col-18 encodes a predicted collagen protein; mRNA is expressed during L2 to dauer and L4 to adult larval id: WBGene00000607 label: col-18 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000607 - allele: - class: variation id: WBVar01211085 label: gk641157 - class: variation id: WBVar01211084 label: gk706795 - class: variation id: WBVar01211082 label: gk532490 - class: variation id: WBVar01211088 label: gk763008 - class: variation id: WBVar01499888 label: gk964029 - class: variation id: WBVar01211068 label: gk638975 - class: variation id: WBVar01211089 label: gk663729 - class: variation id: WBVar00525271 label: gk302028 - class: variation id: WBVar01499519 label: gk963581 - class: variation id: WBVar00253168 label: ttTi327 - class: variation id: WBVar01211087 label: gk357099 - class: variation id: WBVar01211081 label: gk522046 - class: variation id: WBVar00092453 label: ok1198 - class: variation id: WBVar01211075 label: gk600930 - class: variation id: WBVar01499710 label: gk963810 - class: variation id: WBVar01499887 label: gk964028 - class: variation id: WBVar01211076 label: gk460189 - class: variation id: WBVar01211069 label: gk394282 - class: variation id: WBVar01211072 label: gk454625 - class: variation id: WBVar01211090 label: gk687849 - class: variation id: WBVar01211080 label: gk357590 - class: variation id: WBVar01211077 label: gk361743 - class: variation id: WBVar00525269 label: gk302026 - class: variation id: WBVar01211074 label: gk384567 - class: variation id: WBVar01211078 label: gk359430 - class: variation id: WBVar01211086 label: gk745140 - class: variation id: WBVar01211070 label: gk547844 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar00525270 label: gk302027 - class: variation id: WBVar01211079 label: gk853977 - class: variation id: WBVar01211083 label: gk866443 - class: variation id: WBVar00266139 label: ttTi53810 - class: variation id: WBVar01211073 label: gk597011 - class: variation id: WBVar01211071 label: gk357098 - class: variation id: WBVar00525272 label: gk302029 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar00250911 label: tm1951 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables ubiquitin binding activity. Involved in synapse pruning. Predicted to be located in nucleus. Expressed in neurons. Is an ortholog of human DMRT3 (doublesex and mab-3 related transcription factor 3). label: dmd-4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human DMRT3 (doublesex and mab-3 related transcription factor 3). id: WBGene00007776 label: dmd-4 other_names: - C27C12.6 - tag-248 - CELE_C27C12.6 - CE23560 - C27C12.6.1 - C27C12.6 taxonomy: c_elegans other_names: - C27C12.6 - tag-248 - CELE_C27C12.6 - CE23560 - C27C12.6.1 - C27C12.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007776 - allele: - class: variation id: WBVar01499528 label: gk963591 - class: variation id: WBVar01017603 label: gk429803 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01017600 label: gk764099 - class: variation id: WBVar01017599 label: gk346218 - class: variation id: WBVar01017604 label: gk401424 - class: variation id: WBVar01017606 label: gk598689 - class: variation id: WBVar01500066 label: gk964259 - class: variation id: WBVar01499740 label: gk963850 - class: variation id: WBVar01017605 label: gk772605 - class: variation id: WBVar00460232 label: gk236989 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar00460234 label: gk236991 - class: variation id: WBVar00460233 label: gk236990 - class: variation id: WBVar01017602 label: gk571559 - class: variation id: WBVar01017608 label: gk511920 - class: variation id: WBVar01499496 label: gk963553 - class: variation id: WBVar01017601 label: gk695853 - class: variation id: WBVar01017607 label: gk714908 - class: variation id: WBVar01499173 label: gk963041 - class: variation id: WBVar01499174 label: gk963042 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by adr-1 and daf-18 based on RNA-seq studies. Is affected by CGP37157 based on RNA-seq studies. label: T28C12.15 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by adr-1 and daf-18 based on RNA-seq studies. id: WBGene00271821 label: T28C12.15 other_names: - T28C12.15 - CELE_T28C12.15 - T28C12.15.1 - CE52053 - T28C12.15 taxonomy: c_elegans other_names: - T28C12.15 - CELE_T28C12.15 - T28C12.15.1 - CE52053 - T28C12.15 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00271821 - allele: - class: variation id: WBVar01498579 label: gk963400 - class: variation id: WBVar00755731 label: gk759055 - class: variation id: WBVar00755717 label: gk375585 - class: variation id: WBVar00373941 label: gk150698 - class: variation id: WBVar00755711 label: gk391075 - class: variation id: WBVar00755722 label: gk372956 - class: variation id: WBVar00755713 label: gk589285 - class: variation id: WBVar00755734 label: gk934162 - class: variation id: WBVar00755738 label: gk490082 - class: variation id: WBVar00755739 label: gk393026 - class: variation id: WBVar01499017 label: gk962798 - class: variation id: WBVar00755742 label: gk741418 - class: variation id: WBVar00755740 label: gk859909 - class: variation id: WBVar00755743 label: gk876671 - class: variation id: WBVar00755729 label: gk779603 - class: variation id: WBVar00373943 label: gk150700 - class: variation id: WBVar00373940 label: gk150697 - class: variation id: WBVar00373944 label: gk150701 - class: variation id: WBVar00755735 label: gk377663 - class: variation id: WBVar02146654 label: tm8373 - class: variation id: WBVar00373938 label: gk150695 - class: variation id: WBVar00755715 label: gk466583 - class: variation id: WBVar00373945 label: gk150702 - class: variation id: WBVar00755721 label: gk398202 - class: variation id: WBVar00755745 label: gk432837 - class: variation id: WBVar00755726 label: gk709359 - class: variation id: WBVar00755746 label: gk720334 - class: variation id: WBVar00755714 label: gk377097 - class: variation id: WBVar00755737 label: gk832711 - class: variation id: WBVar01498940 label: gk962682 - class: variation id: WBVar00755744 label: gk492561 - class: variation id: WBVar00755719 label: gk601884 - class: variation id: WBVar00755728 label: gk774471 - class: variation id: WBVar00755748 label: gk849327 - class: variation id: WBVar00755716 label: gk870807 - class: variation id: WBVar00755718 label: gk903504 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00755724 label: gk786602 - class: variation id: WBVar00755747 label: gk686608 - class: variation id: WBVar00755723 label: gk464636 - class: variation id: WBVar00755730 label: gk835496 - class: variation id: WBVar00373942 label: gk150699 - class: variation id: WBVar00373936 label: gk150693 - class: variation id: WBVar00276551 label: ok5062 - class: variation id: WBVar00373939 label: gk150696 - class: variation id: WBVar00755712 label: gk805165 - class: variation id: WBVar00755733 label: gk342122 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00755720 label: gk777029 - class: variation id: WBVar00373946 label: gk150703 - class: variation id: WBVar00755732 label: gk398203 - class: variation id: WBVar00373937 label: gk150694 - class: variation id: WBVar00093702 label: ok2579 - class: variation id: WBVar00066569 label: cxTi4505 - class: variation id: WBVar00755741 label: gk312158 - class: variation id: WBVar00755736 label: gk606969 - class: variation id: WBVar00755725 label: gk727209 - class: variation id: WBVar00755727 label: gk853471 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Expressed in head; intestine; and vulva. Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: F42A8.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00009626 label: F42A8.1 other_names: - F42A8.1 - CELE_F42A8.1 - F42A8.1 - CE01578 - F42A8.1.1 taxonomy: c_elegans other_names: - F42A8.1 - CELE_F42A8.1 - F42A8.1 - CE01578 - F42A8.1.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00009626 - allele: - class: variation id: WBVar00146627 label: h662 - class: variation id: WBVar00143904 label: e1304 - class: variation id: WBVar00409262 label: gk186019 - class: variation id: WBVar00862237 label: gk628891 - class: variation id: WBVar00862246 label: gk843396 - class: variation id: WBVar00862250 label: gk348462 - class: variation id: WBVar00143150 label: e364 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar00862247 label: gk534157 - class: variation id: WBVar00862241 label: gk325232 - class: variation id: WBVar00862251 label: gk595078 - class: variation id: WBVar00409269 label: gk186026 - class: variation id: WBVar00409274 label: gk186031 - class: variation id: WBVar00091485 label: ok162 - class: variation id: WBVar00862258 label: gk854874 - class: variation id: WBVar00862255 label: gk533365 - class: variation id: WBVar00409276 label: gk186033 - class: variation id: WBVar00862253 label: gk327514 - class: variation id: WBVar00862236 label: gk341101 - class: variation id: WBVar00143254 label: e499 - class: variation id: WBVar00143738 label: e1096 - class: variation id: WBVar00862265 label: gk863934 - class: variation id: WBVar00143134 label: e346 - class: variation id: WBVar00409272 label: gk186029 - class: variation id: WBVar00409266 label: gk186023 - class: variation id: WBVar00409277 label: gk186034 - class: variation id: WBVar00409264 label: gk186021 - class: variation id: WBVar00862233 label: gk535588 - class: variation id: WBVar00862257 label: gk450603 - class: variation id: WBVar00862242 label: gk584505 - class: variation id: WBVar00409270 label: gk186027 - class: variation id: WBVar00409267 label: gk186024 - class: variation id: WBVar00862260 label: gk778044 - class: variation id: WBVar00862235 label: gk773597 - class: variation id: WBVar00409263 label: gk186020 - class: variation id: WBVar00862252 label: gk739504 - class: variation id: WBVar00862249 label: gk595077 - class: variation id: WBVar00862262 label: gk727318 - class: variation id: WBVar00862243 label: gk512280 - class: variation id: WBVar00862240 label: gk615592 - class: variation id: WBVar00862264 label: gk562392 - class: variation id: WBVar01499987 label: gk964161 - class: variation id: WBVar00143141 label: e354 - class: variation id: WBVar00862245 label: gk521040 - class: variation id: WBVar00241998 label: s1304 - class: variation id: WBVar00143877 label: e1270 - class: variation id: WBVar00241825 label: s361 - class: variation id: WBVar00862238 label: gk542418 - class: variation id: WBVar00409265 label: gk186022 - class: variation id: WBVar00862261 label: gk565194 - class: variation id: WBVar00862244 label: gk580011 - class: variation id: WBVar00409271 label: gk186028 - class: variation id: WBVar00862259 label: gk557678 - class: variation id: WBVar00862254 label: gk356374 - class: variation id: WBVar00409268 label: gk186025 - class: variation id: WBVar00241999 label: s1305 - class: variation id: WBVar00144368 label: e1862 - class: variation id: WBVar00242000 label: s1306 - class: variation id: WBVar00862263 label: gk717407 - class: variation id: WBVar00409273 label: gk186030 - class: variation id: WBVar00862232 label: gk597808 - class: variation id: WBVar00862239 label: gk567283 - class: variation id: WBVar00000568 label: bx26 - class: variation id: WBVar00862256 label: gk766185 - class: variation id: WBVar00862234 label: gk827406 - class: variation id: WBVar00409275 label: gk186032 - class: variation id: WBVar00862248 label: gk437518 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables procollagen-proline 4-dioxygenase activity. Involved in several processes, including cuticle development involved in collagen and cuticulin-based cuticle molting cycle; embryo development; and embryonic body morphogenesis. Located in endoplasmic reticulum. Expressed in hypodermis; muscle cell; neurons; and pharynx. Human ortholog(s) of this gene implicated in myopia. Is an ortholog of human P4HA1 (prolyl 4-hydroxylase subunit alpha 1) and P4HA2 (prolyl 4-hydroxylase subunit alpha 2). label: dpy-18 legacy_description: "dpy-18 encodes a catalytic alpha subunit of collagen prolyl 4-hydroxylase (P4H) orthologous to human P4H alpha (I) isoform (OMIM: 176710), an alpha subunit of prolyl-4-hydroxylase which is a procollagen modifying enzyme required for exoskeleton formation, morphogenesis and maintenance of body shape; dpy-18 has a critical role in hydroxylation of cuticle collagens during collagen synthesis; dpy-18, in complex with phy-2, is essential for the survival of the C. elegans; dpy-18 mutations alone result in a mild dumpy phenotype; expressed dpy-18 and ten-1 act in parallel influencing the connection between epidermis and muscle during embryonic development; deletion of dpy-18 causes aggregation of collagen IV in body wall muscles in elongated embryos and triggers the loss of tissue integrity in ten-1 mutants; dpy-18 is expressed throughout the hypodermis, head and posterior neurons." merged_into: ~ name: class: gene highlight: description_all: - dpy-18 encodes a catalytic alpha subunit of collagen prolyl 4-hydroxylase (P4H) orthologous to human - modifying enzyme required for exoskeleton formation, morphogenesis and maintenance of body shape; dpy-18 - with phy-2, is essential for the survival of the C. elegans; dpy-18 mutations alone result in a mild - and muscle during embryonic development; deletion of dpy-18 causes aggregation of collagen IV in body - wall muscles in elongated embryos and triggers the loss of tissue integrity in ten-1 mutants; dpy-18 id: WBGene00001077 label: dpy-18 other_names: - Y47D3B.10 - phy-1 - CELE_Y47D3B.10 - T28D6.1 - CE20261 - Y47D3B.10.1 - Y47D3B.10 taxonomy: c_elegans other_names: - Y47D3B.10 - phy-1 - CELE_Y47D3B.10 - T28D6.1 - CE20261 - Y47D3B.10.1 - Y47D3B.10 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001077 - allele: - class: variation id: WBVar00935914 label: gk869029 - class: variation id: WBVar00318723 label: snx1151 - class: variation id: WBVar00433479 label: gk210236 - class: variation id: WBVar00322428 label: snx4856 - class: variation id: WBVar00433482 label: gk210239 - class: variation id: WBVar00935912 label: gk742921 - class: variation id: WBVar00433486 label: gk210243 - class: variation id: WBVar00433483 label: gk210240 - class: variation id: WBVar00935907 label: gk676981 - class: variation id: WBVar00433478 label: gk210235 - class: variation id: WBVar00935913 label: gk385831 - class: variation id: WBVar00935916 label: gk776038 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00433481 label: gk210238 - class: variation id: WBVar00935911 label: gk793045 - class: variation id: WBVar00433485 label: gk210242 - class: variation id: WBVar00935910 label: gk445474 - class: variation id: WBVar00935915 label: gk375673 - class: variation id: WBVar00935909 label: gk731641 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar00433480 label: gk210237 - class: variation id: WBVar00935918 label: gk877633 - class: variation id: WBVar00935908 label: gk525273 - class: variation id: WBVar00935917 label: gk844927 - class: variation id: WBVar00935919 label: gk893342 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00320568 label: snx2996 - class: variation id: WBVar00433484 label: gk210241 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Predicted to be located in nucleus. Is an ortholog of human CHTF18 (chromosome transmission fidelity factor 18). label: ctf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human CHTF18 (chromosome transmission fidelity factor 18). id: WBGene00010676 label: ctf-18 other_names: - K08F4.1 - CELE_K08F4.1 - CE06149 - K08F4.1.1 - K08F4.1 taxonomy: c_elegans other_names: - K08F4.1 - CELE_K08F4.1 - CE06149 - K08F4.1.1 - K08F4.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00010676 - allele: - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01499903 label: gk964052 - class: variation id: WBVar01499056 label: gk962860 - class: variation id: WBVar01033287 label: gk314728 - class: variation id: WBVar01499420 label: gk963442 - class: variation id: WBVar01033286 label: gk311909 - class: variation id: WBVar01033288 label: gk562581 - class: variation id: WBVar01499419 label: gk963441 - class: variation id: WBVar01500129 label: gk964351 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity and protein heterodimerization activity. Predicted to be a structural constituent of chromatin. Is an ortholog of several human genes including H4C1 (H4 clustered histone 1); H4C4 (H4 clustered histone 4); and H4C9 (H4 clustered histone 9). label: his-18 legacy_description: his-18 encodes an H4 histone; by homology, HIS-18 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-18 is a replication-dependent histone locus that resides in the HIS4 cluster on chromosome V. merged_into: ~ name: class: gene highlight: description_all: - his-18 encodes an H4 histone; by homology, HIS-18 is predicted to function as a nucleosome component - required for packaging of DNA into chromatin; his-18 is a replication-dependent histone locus that resides id: WBGene00001892 label: his-18 other_names: - K06C4.10 - CELE_K06C4.10 - CE03252 - K06C4.10.1 - K06C4.10 taxonomy: c_elegans other_names: - K06C4.10 - CELE_K06C4.10 - CE03252 - K06C4.10.1 - K06C4.10 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001892 - allele: - class: variation id: WBVar01499642 label: gk963732 - class: variation id: WBVar00143008 label: e174 - class: variation id: WBVar02139615 label: h9777 - class: variation id: WBVar00088849 label: md1412 - class: variation id: WBVar01162510 label: gk331918 - class: variation id: WBVar01499781 label: gk963896 - class: variation id: WBVar00054252 label: cn347 - class: variation id: WBVar01162498 label: gk886894 - class: variation id: WBVar02153378 label: ulv12 - class: variation id: WBVar00088827 label: md1094 - class: variation id: WBVar01162493 label: gk929530 - class: variation id: WBVar00088810 label: md183 - class: variation id: WBVar01162507 label: gk500833 - class: variation id: WBVar00088825 label: md426 - class: variation id: WBVar00144595 label: e2146 - class: variation id: WBVar00088820 label: md299 - class: variation id: WBVar01162497 label: gk670592 - class: variation id: WBVar00088812 label: md193 - class: variation id: WBVar00509006 label: gk285763 - class: variation id: WBVar01162505 label: gk716141 - class: variation id: WBVar00509008 label: gk285765 - class: variation id: WBVar01162509 label: gk457865 - class: variation id: WBVar01162504 label: gk914463 - class: variation id: WBVar01162496 label: gk512025 - class: variation id: WBVar01500012 label: gk964193 - class: variation id: WBVar01498655 label: gk963746 - class: variation id: WBVar01162503 label: gk579231 - class: variation id: WBVar01162502 label: gk891423 - class: variation id: WBVar00143053 label: e234 - class: variation id: WBVar01162492 label: gk817153 - class: variation id: WBVar00088836 label: md1264 - class: variation id: WBVar00509007 label: gk285764 - class: variation id: WBVar00249029 label: sy671 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01162508 label: gk379132 - class: variation id: WBVar01162500 label: gk724592 - class: variation id: WBVar00088841 label: md1307 - class: variation id: WBVar01162511 label: gk358461 - class: variation id: WBVar01499933 label: gk964087 - class: variation id: WBVar00142951 label: e81 - class: variation id: WBVar01499934 label: gk964088 - class: variation id: WBVar00509009 label: gk285766 - class: variation id: WBVar01500013 label: gk964194 - class: variation id: WBVar01162501 label: gk449532 - class: variation id: WBVar01162499 label: gk480759 - class: variation id: WBVar01162495 label: gk508272 - class: variation id: WBVar00088802 label: md120 - class: variation id: WBVar00088848 label: md1401 - class: variation id: WBVar01162494 label: gk523091 - class: variation id: WBVar01162506 label: gk732660 - class: variation id: WBVar00251968 label: tm3212 - class: variation id: WBVar01162491 label: gk712915 - class: variation id: WBVar00144711 label: e2291 - class: variation id: WBVar00088801 label: md118 - class: variation id: WBVar00000406 label: b403 - class: variation id: WBVar00509005 label: gk285762 - class: variation id: WBVar00509010 label: gk285767 - class: variation id: WBVar00094473 label: ok3477 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables syntaxin binding activity. Involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. Located in axon. Expressed in head neurons; intestine; nervous system; uv1; and ventral cord neurons. Used to study alcohol use disorder and developmental and epileptic encephalopathy. Human ortholog(s) of this gene implicated in West syndrome; developmental and epileptic encephalopathy 4; and familial hemophagocytic lymphohistiocytosis 5. Is an ortholog of human STXBP1 (syntaxin binding protein 1). label: unc-18 legacy_description: unc-18 encodes the C. elegans ortholog of Saccharomyces cervisiae SEC1 and mammalian Munc18 proteins; UNC-18 function as a chaperone for UNC-64/syntaxin, ensuring its anterograde transport from the endoplasmic reticulum to the plasma membrane; UNC-18 also enables the docking of vesicles to synaptic regions before vesicle priming and fusion, and promotes synaptic vesicle exocytosis; UNC-18 may also inhibit excessive exocytosis; UNC-18 is expressed in ventral cord motor neurons. merged_into: ~ name: class: gene highlight: description_all: - unc-18 encodes the C. elegans ortholog of Saccharomyces cervisiae SEC1 and mammalian Munc18 proteins; - UNC-18 function as a chaperone for UNC-64/syntaxin, ensuring its anterograde transport from the endoplasmic - reticulum to the plasma membrane; UNC-18 also enables the docking of vesicles to synaptic regions before - vesicle priming and fusion, and promotes synaptic vesicle exocytosis; UNC-18 may also inhibit excessive - exocytosis; UNC-18 is expressed in ventral cord motor neurons. id: WBGene00006757 label: unc-18 other_names: - F27D9.1 - unc-19 - lan-2 - CELE_F27D9.1 - F27D9.1a.1 - F27D9.1b - F27D9.1a - CE24927 taxonomy: c_elegans other_names: - F27D9.1 - unc-19 - lan-2 - CELE_F27D9.1 - F27D9.1a.1 - F27D9.1b - F27D9.1a - CE24927 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006757 - allele: - class: variation id: WBVar00840998 label: gk656728 - class: variation id: WBVar00841007 label: gk394012 - class: variation id: WBVar00841021 label: gk466644 - class: variation id: WBVar01492328 label: gk956591 - class: variation id: WBVar00841006 label: gk821144 - class: variation id: WBVar00402163 label: gk178920 - class: variation id: WBVar00402172 label: gk178929 - class: variation id: WBVar00402161 label: gk178918 - class: variation id: WBVar00841010 label: gk727298 - class: variation id: WBVar00144552 label: e2088 - class: variation id: WBVar00841019 label: gk570382 - class: variation id: WBVar00841003 label: gk631702 - class: variation id: WBVar00144480 label: e2011 - class: variation id: WBVar00841004 label: gk781743 - class: variation id: WBVar00402164 label: gk178921 - class: variation id: WBVar00402168 label: gk178925 - class: variation id: WBVar00841017 label: gk584487 - class: variation id: WBVar00840999 label: gk457165 - class: variation id: WBVar00144408 label: e1936 - class: variation id: WBVar00402171 label: gk178928 - class: variation id: WBVar01500260 label: gk964518 - class: variation id: WBVar00841023 label: gk385461 - class: variation id: WBVar00841024 label: gk479908 - class: variation id: WBVar00841014 label: gk503790 - class: variation id: WBVar00840995 label: gk925292 - class: variation id: WBVar00841011 label: gk916376 - class: variation id: WBVar00143853 label: e1239 - class: variation id: WBVar00144280 label: e1751 - class: variation id: WBVar00841009 label: gk392740 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar00841000 label: gk745813 - class: variation id: WBVar00402162 label: gk178919 - class: variation id: WBVar00402169 label: gk178926 - class: variation id: WBVar00841025 label: gk440104 - class: variation id: WBVar00840997 label: gk601256 - class: variation id: WBVar00841022 label: gk891080 - class: variation id: WBVar00841008 label: gk822782 - class: variation id: WBVar00841013 label: gk898289 - class: variation id: WBVar00840996 label: gk883842 - class: variation id: WBVar00402170 label: gk178927 - class: variation id: WBVar00402165 label: gk178922 - class: variation id: WBVar00841002 label: gk842348 - class: variation id: WBVar00275784 label: ok5304 - class: variation id: WBVar00840994 label: gk368835 - class: variation id: WBVar00841020 label: gk738574 - class: variation id: WBVar00841018 label: gk799226 - class: variation id: WBVar00841015 label: gk738573 - class: variation id: WBVar00089233 label: mu114 - class: variation id: WBVar00402167 label: gk178924 - class: variation id: WBVar00841016 label: gk872493 - class: variation id: WBVar00145999 label: gk670 - class: variation id: WBVar00402166 label: gk178923 - class: variation id: WBVar00841001 label: gk763836 - class: variation id: WBVar00841005 label: gk547441 - class: variation id: WBVar00000584 label: bx54 - class: variation id: WBVar00840993 label: gk319976 - class: variation id: WBVar00841012 label: gk507344 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. Located in nucleus. Part of RNA polymerase II transcription regulator complex. Expressed in several structures, including body ganglion; body wall musculature; male-specific anatomical entity; neurons; and vulval cell. Is an ortholog of human HOXB8 (homeobox B8) and HOXC8 (homeobox C8). label: mab-5 legacy_description: mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog. merged_into: ~ name: class: gene highlight: description_all: - mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A - family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously - alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab - act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab - several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB id: WBGene00003102 label: mab-5 other_names: - C08C3.3 - lin-21 - CELE_C08C3.3 - CE25765 - C08C3.3 - C08C3.3.1 taxonomy: c_elegans other_names: - C08C3.3 - lin-21 - CELE_C08C3.3 - CE25765 - C08C3.3 - C08C3.3.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003102 - allele: - class: variation id: WBVar01046394 label: gk529857 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01046392 label: gk515603 - class: variation id: WBVar00469916 label: gk246673 - class: variation id: WBVar01046393 label: gk425716 - class: variation id: WBVar00469915 label: gk246672 - class: variation id: WBVar01499645 label: gk963736 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01046395 label: gk877712 - class: variation id: WBVar01046390 label: gk904630 - class: variation id: WBVar01500209 label: gk964452 - class: variation id: WBVar01046396 label: gk787442 - class: variation id: WBVar01046391 label: gk384468 - class: variation id: WBVar00469914 label: gk246671 - class: variation id: WBVar01046397 label: gk627178 - class: variation id: WBVar02151733 label: tm11399 - class: variation id: WBVar01500208 label: gk964451 - class: variation id: WBVar01046389 label: gk735467 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in mitochondrion. Is an ortholog of human HSDL2 (hydroxysteroid dehydrogenase like 2). label: dhs-18 legacy_description: dhs-18 encodes a predicted short-chain dehydrogenase. merged_into: ~ name: class: gene highlight: description_all: - dhs-18 encodes a predicted short-chain dehydrogenase. id: WBGene00000981 label: dhs-18 other_names: - C45B11.3 - CELE_C45B11.3 - CE05427 - C45B11.3 - C45B11.3.1 taxonomy: c_elegans other_names: - C45B11.3 - CELE_C45B11.3 - CE05427 - C45B11.3 - C45B11.3.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000981 - allele: - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01499398 label: gk963419 - class: variation id: WBVar01193827 label: gk751039 - class: variation id: WBVar01499710 label: gk963810 - class: variation id: WBVar01193822 label: gk703686 - class: variation id: WBVar01193824 label: gk733986 - class: variation id: WBVar00519342 label: gk296099 - class: variation id: WBVar00094141 label: ok3059 - class: variation id: WBVar01193826 label: gk772747 - class: variation id: WBVar00317160 label: otn20339 - class: variation id: WBVar02150184 label: tm12615 - class: variation id: WBVar00519344 label: gk296101 - class: variation id: WBVar00519343 label: gk296100 - class: variation id: WBVar01193820 label: gk899272 - class: variation id: WBVar00519345 label: gk296102 - class: variation id: WBVar01499399 label: gk963420 - class: variation id: WBVar01193821 label: gk772746 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar02140245 label: h11992 - class: variation id: WBVar01193825 label: gk809496 - class: variation id: WBVar01499887 label: gk964028 - class: variation id: WBVar01193823 label: gk872245 - class: variation id: WBVar01499888 label: gk964029 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by daf-18 and sir-2.1 based on RNA-seq and microarray studies. Is affected by cadmium and Sirolimus based on microarray studies. label: F17A2.16 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by daf-18 and sir-2.1 based on RNA-seq and microarray studies. id: WBGene00304215 label: F17A2.16 other_names: - F17A2.16 - CELE_F17A2.16 - F17A2.16.1 - F17A2.16 - CE52819 taxonomy: c_elegans other_names: - F17A2.16 - CELE_F17A2.16 - F17A2.16.1 - F17A2.16 - CE52819 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00304215 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: erf-5 legacy_description: erf-5 was identified in screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab-20/semaphorin-2A; the molecular identity of erf-5 is not yet known. merged_into: ~ name: class: gene highlight: description_all: - screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab id: WBGene00007035 label: erf-5 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007035 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: erf-3 legacy_description: erf-3 was identified in screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab-20/semaphorin-2A; the molecular identity of erf-3 is not yet known. merged_into: ~ name: class: gene highlight: description_all: - screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab id: WBGene00007033 label: erf-3 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007033 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: erf-4 legacy_description: erf-4 was identified in screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab-20/semaphorin-2A; the molecular identity of erf-4 is not yet known. merged_into: ~ name: class: gene highlight: description_all: - screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab id: WBGene00007034 label: erf-4 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007034 - allele: - class: variation id: WBVar01477393 label: gk941651 - class: variation id: WBVar00725983 label: gk617721 - class: variation id: WBVar00364123 label: gk140880 - class: variation id: WBVar00364122 label: gk140879 - class: variation id: WBVar00364131 label: gk140888 - class: variation id: WBVar00726000 label: gk607594 - class: variation id: WBVar01477389 label: gk941647 - class: variation id: WBVar00725974 label: gk827253 - class: variation id: WBVar01477390 label: gk941648 - class: variation id: WBVar01477391 label: gk941649 - class: variation id: WBVar00725990 label: gk862464 - class: variation id: WBVar00364125 label: gk140882 - class: variation id: WBVar00725985 label: gk520881 - class: variation id: WBVar00364127 label: gk140884 - class: variation id: WBVar02129801 label: h3550 - class: variation id: WBVar00725996 label: gk526678 - class: variation id: WBVar00725978 label: gk792245 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00070749 label: cxTi9216 - class: variation id: WBVar00250142 label: tm1125 - class: variation id: WBVar01477392 label: gk941650 - class: variation id: WBVar00725975 label: gk907830 - class: variation id: WBVar00725992 label: gk666981 - class: variation id: WBVar00725972 label: gk501998 - class: variation id: WBVar00725991 label: gk448806 - class: variation id: WBVar00725977 label: gk438137 - class: variation id: WBVar00725987 label: gk721300 - class: variation id: WBVar00364129 label: gk140886 - class: variation id: WBVar00725986 label: gk864361 - class: variation id: WBVar01496537 label: gk960800 - class: variation id: WBVar00725970 label: gk865880 - class: variation id: WBVar00725994 label: gk729393 - class: variation id: WBVar00725993 label: gk546468 - class: variation id: WBVar00725999 label: gk619463 - class: variation id: WBVar00725979 label: gk777012 - class: variation id: WBVar00725998 label: gk425649 - class: variation id: WBVar00725988 label: gk606232 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00364128 label: gk140885 - class: variation id: WBVar00364126 label: gk140883 - class: variation id: WBVar00364121 label: gk140878 - class: variation id: WBVar00725973 label: gk432628 - class: variation id: WBVar00725984 label: gk784501 - class: variation id: WBVar00725989 label: gk603336 - class: variation id: WBVar00725980 label: gk376832 - class: variation id: WBVar00364130 label: gk140887 - class: variation id: WBVar00364124 label: gk140881 - class: variation id: WBVar00725997 label: gk892204 - class: variation id: WBVar00725971 label: gk514838 - class: variation id: WBVar00725976 label: gk785189 - class: variation id: WBVar00725981 label: gk617719 - class: variation id: WBVar00725995 label: gk751872 - class: variation id: WBVar00725982 label: gk617720 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein-macromolecule adaptor activity. Involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. Located in cytoplasm. Expressed in body wall musculature; coelomocyte; hermaphrodite gonad; hypodermis; and intestine. Is an ortholog of human VPS18 (VPS18 core subunit of CORVET and HOPS complexes). label: vps-18 legacy_description: vps-18 encodes the C. elegans ortholog of the vacuolar sorting protein VPS18/Vps18p; vps-18 activity is essential for formation of early endosomes, late endosomes, and lysosomes and thus, for endosome-lysosome trafficking and lysosomal protein degradation; vps-18 thus also plays a role in phagosome maturation during apoptotic cell degradation. merged_into: ~ name: class: gene highlight: description_all: - vps-18 encodes the C. elegans ortholog of the vacuolar sorting protein VPS18/Vps18p; vps-18 activity - endosomes, and lysosomes and thus, for endosome-lysosome trafficking and lysosomal protein degradation; vps-18 id: WBGene00021058 label: vps-18 other_names: - W06B4.3 - CELE_W06B4.3 - W06B4.3 - CE43757 - W06B4.3.1 taxonomy: c_elegans other_names: - W06B4.3 - CELE_W06B4.3 - W06B4.3 - CE43757 - W06B4.3.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00021058 - allele: - class: variation id: WBVar00815692 label: gk761987 - class: variation id: WBVar00815695 label: gk792340 - class: variation id: WBVar00815696 label: gk647153 - class: variation id: WBVar00815698 label: gk824788 - class: variation id: WBVar00394008 label: gk170765 - class: variation id: WBVar00300939 label: otn4118 - class: variation id: WBVar00815703 label: gk745373 - class: variation id: WBVar00394011 label: gk170768 - class: variation id: WBVar00815699 label: gk808593 - class: variation id: WBVar00815697 label: gk878019 - class: variation id: WBVar00815694 label: gk523958 - class: variation id: WBVar02131749 label: h3326 - class: variation id: WBVar01500142 label: gk964368 - class: variation id: WBVar00394009 label: gk170766 - class: variation id: WBVar01500082 label: gk964281 - class: variation id: WBVar00815693 label: gk351948 - class: variation id: WBVar00815700 label: gk911725 - class: variation id: WBVar00815702 label: gk872999 - class: variation id: WBVar00815691 label: gk406185 - class: variation id: WBVar00394012 label: gk170769 - class: variation id: WBVar01498832 label: gk962532 - class: variation id: WBVar00815701 label: gk488652 - class: variation id: WBVar00815704 label: gk312174 - class: variation id: WBVar01473798 label: tm6054 - class: variation id: WBVar00394010 label: gk170767 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein-L-histidine N-tele-methyltransferase activity. Predicted to be involved in methylation. Is an ortholog of human METTL18 (methyltransferase 18, RPL3 N3(tau)-histidine). label: metl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human METTL18 (methyltransferase 18, RPL3 N3(tau)-histidine). id: WBGene00010450 label: metl-18 other_names: - K01A11.2 - CELE_K01A11.2 - CE03450 - K01A11.2 - K01A11.2.1 taxonomy: c_elegans other_names: - K01A11.2 - CELE_K01A11.2 - CE03450 - K01A11.2 - K01A11.2.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00010450 - allele: - class: variation id: WBVar00956094 label: gk816309 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00440328 label: gk217085 - class: variation id: WBVar00956080 label: gk844952 - class: variation id: WBVar00956091 label: gk671984 - class: variation id: WBVar00956082 label: gk858714 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar00956083 label: gk389472 - class: variation id: WBVar00956089 label: gk877256 - class: variation id: WBVar00956090 label: gk354943 - class: variation id: WBVar01482663 label: gk946923 - class: variation id: WBVar00956093 label: gk388452 - class: variation id: WBVar01499951 label: gk964110 - class: variation id: WBVar00956087 label: gk555234 - class: variation id: WBVar00956081 label: gk763298 - class: variation id: WBVar00093381 label: ok2217 - class: variation id: WBVar01499952 label: gk964111 - class: variation id: WBVar02135023 label: h8983 - class: variation id: WBVar00956084 label: gk619143 - class: variation id: WBVar01499609 label: gk963691 - class: variation id: WBVar01499493 label: gk963547 - class: variation id: WBVar00440327 label: gk217084 - class: variation id: WBVar00956092 label: gk509776 - class: variation id: WBVar01482664 label: gk946924 - class: variation id: WBVar00956085 label: gk812560 - class: variation id: WBVar00956086 label: gk780945 - class: variation id: WBVar00956088 label: gk323835 - class: variation id: WBVar01499492 label: gk963546 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar01499610 label: gk963692 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. Is an ortholog of human RPL18 (ribosomal protein L18). label: rpl-18 legacy_description: rpl-18 encodes a large ribosomal subunit L18 protein. merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 18. - rpl-18 encodes a large ribosomal subunit L18 protein. id: WBGene00004430 label: rpl-18 other_names: - Y45F10D.12 - CELE_Y45F10D.12 - CE16650 - Y45F10D.12.1 - Y45F10D.12 taxonomy: c_elegans other_names: - Y45F10D.12 - CELE_Y45F10D.12 - CE16650 - Y45F10D.12.1 - Y45F10D.12 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004430 - allele: - class: variation id: WBVar01166829 label: gk847413 - class: variation id: WBVar02151768 label: tm11434 - class: variation id: WBVar02151771 label: tm11437 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01499781 label: gk963896 - class: variation id: WBVar01499642 label: gk963732 - class: variation id: WBVar01500012 label: gk964193 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar01500013 label: gk964194 - class: variation id: WBVar01499963 label: gk964126 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-2; daf-18; and lem-2 based on RNA-seq and microarray studies. Is affected by Ethanol based on RNA-seq studies. label: R09F10.17 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-2; daf-18; and lem-2 based on RNA-seq and microarray studies id: WBGene00199134 label: R09F10.17 other_names: - R09F10.17 - CELE_R09F10.17 - R09F10.17 taxonomy: c_elegans other_names: - R09F10.17 - CELE_R09F10.17 - R09F10.17 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00199134 - allele: - class: variation id: WBVar00671631 label: gk585955 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar02128509 label: h14520 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar01499229 label: gk963137 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar01499788 label: gk963906 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in excretory gland cell based on single-cell RNA-seq studies. Is affected by pmt-2; daf-2; and daf-18 based on microarray and RNA-seq studies. label: F36D1.15 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by pmt-2; daf-2; and daf-18 based on microarray and RNA-seq studies. id: WBGene00195232 label: F36D1.15 other_names: - F36D1.15 - CELE_F36D1.15 - F36D1.15.1 - CE45254 - F36D1.15 taxonomy: c_elegans other_names: - F36D1.15 - CELE_F36D1.15 - F36D1.15.1 - CE45254 - F36D1.15 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00195232 - allele: - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar00471417 label: gk248174 - class: variation id: WBVar01050882 label: gk906362 - class: variation id: WBVar01499904 label: gk964054 - class: variation id: WBVar00145002 label: e2795 - class: variation id: WBVar01500213 label: gk964459 - class: variation id: WBVar01050879 label: gk630327 - class: variation id: WBVar01050880 label: gk890728 - class: variation id: WBVar00471419 label: gk248176 - class: variation id: WBVar01050878 label: gk627833 - class: variation id: WBVar01499905 label: gk964055 - class: variation id: WBVar01050883 label: gk400165 - class: variation id: WBVar01050887 label: gk326349 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01050890 label: gk906363 - class: variation id: WBVar00250064 label: tm1045 - class: variation id: WBVar01050888 label: gk850201 - class: variation id: WBVar01484730 label: gk948990 - class: variation id: WBVar01050881 label: gk724517 - class: variation id: WBVar01050885 label: gk658124 - class: variation id: WBVar01050889 label: gk620256 - class: variation id: WBVar02137180 label: h17475 - class: variation id: WBVar01499547 label: gk963618 - class: variation id: WBVar00471416 label: gk248173 - class: variation id: WBVar01500212 label: gk964458 - class: variation id: WBVar01050886 label: gk315532 - class: variation id: WBVar00471420 label: gk248177 - class: variation id: WBVar01050884 label: gk691455 - class: variation id: WBVar01050891 label: gk878794 - class: variation id: WBVar00471418 label: gk248175 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables acyltransferase activity. Involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. Located in endoplasmic reticulum. Expressed in several structures, including AIY; excretory gland cell; hypodermis; interfacial epithelial cell; and vulva. Is an ortholog of human LCLAT1 (lysocardiolipin acyltransferase 1). label: bus-18 legacy_description: bus-18 encodes a lysocardiolipin acyltransferase; bus-18 is required for colonization by Microbacterium nematophilum and the tail-swelling response to M. nematophilum infection, as well as for cuticle integrity, traction during movement, full body size, normally rapid growth, and vulval morphogenesis; bus-18 is also needed for normal cuticle antigens and resistance to emetine or colchicine, perhaps because its cuticle is abnormally permeable. merged_into: ~ name: class: gene highlight: description_all: - bus-18 encodes a lysocardiolipin acyltransferase; bus-18 is required for colonization by Microbacterium - integrity, traction during movement, full body size, normally rapid growth, and vulval morphogenesis; bus-18 id: WBGene00044631 label: bus-18 other_names: - F55A11.5 - CELE_F55A11.5 - acl-10 - F55A11.5.1 - CE39507 - F55A11.5 taxonomy: c_elegans other_names: - F55A11.5 - CELE_F55A11.5 - acl-10 - F55A11.5.1 - CE39507 - F55A11.5 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00044631 - allele: - class: variation id: WBVar01130815 label: gk843646 - class: variation id: WBVar01130819 label: gk704961 - class: variation id: WBVar01130810 label: gk673088 - class: variation id: WBVar01130805 label: gk580918 - class: variation id: WBVar00531876 label: gk3063 - class: variation id: WBVar00498110 label: gk274867 - class: variation id: WBVar01130788 label: gk808339 - class: variation id: WBVar01130799 label: gk805882 - class: variation id: WBVar01130806 label: gk374975 - class: variation id: WBVar00251114 label: tm2179 - class: variation id: WBVar00498113 label: gk274870 - class: variation id: WBVar00498118 label: gk274875 - class: variation id: WBVar01130782 label: gk887934 - class: variation id: WBVar01130809 label: gk355689 - class: variation id: WBVar01130816 label: gk701502 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar01130787 label: gk784348 - class: variation id: WBVar01130797 label: gk789817 - class: variation id: WBVar01130792 label: gk474845 - class: variation id: WBVar01130798 label: gk368256 - class: variation id: WBVar01486615 label: gk950876 - class: variation id: WBVar00498108 label: gk274865 - class: variation id: WBVar01130820 label: gk751679 - class: variation id: WBVar01130781 label: gk882753 - class: variation id: WBVar01130803 label: gk573569 - class: variation id: WBVar01130783 label: gk352979 - class: variation id: WBVar00498116 label: gk274873 - class: variation id: WBVar01130801 label: gk752364 - class: variation id: WBVar01130789 label: gk624896 - class: variation id: WBVar02125029 label: n4766 - class: variation id: WBVar01130808 label: gk327664 - class: variation id: WBVar01130807 label: gk732611 - class: variation id: WBVar01130794 label: gk926719 - class: variation id: WBVar01130784 label: gk619827 - class: variation id: WBVar00498114 label: gk274871 - class: variation id: WBVar01130778 label: gk553998 - class: variation id: WBVar00498117 label: gk274874 - class: variation id: WBVar01486614 label: gk950875 - class: variation id: WBVar01497641 label: gk961904 - class: variation id: WBVar00240765 label: pkP5143 - class: variation id: WBVar01130791 label: gk718626 - class: variation id: WBVar01130817 label: gk574207 - class: variation id: WBVar01130786 label: gk435573 - class: variation id: WBVar00498115 label: gk274872 - class: variation id: WBVar01130785 label: gk329768 - class: variation id: WBVar00498112 label: gk274869 - class: variation id: WBVar01130813 label: gk420885 - class: variation id: WBVar01130793 label: gk844433 - class: variation id: WBVar01130796 label: gk585478 - class: variation id: WBVar00498107 label: gk274864 - class: variation id: WBVar01130795 label: gk692684 - class: variation id: WBVar01130790 label: gk699707 - class: variation id: WBVar00498111 label: gk274868 - class: variation id: WBVar01130802 label: gk808796 - class: variation id: WBVar01130780 label: gk323070 - class: variation id: WBVar01130818 label: gk686380 - class: variation id: WBVar01130804 label: gk580917 - class: variation id: WBVar01130814 label: gk614640 - class: variation id: WBVar00498109 label: gk274866 - class: variation id: WBVar02125005 label: db99 - class: variation id: WBVar01130779 label: gk844432 - class: variation id: WBVar01130800 label: gk800338 - class: variation id: WBVar01130811 label: gk666239 - class: variation id: WBVar01130812 label: gk775630 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable neuropeptide Y receptor binding activity. Involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. Predicted to be located in extracellular space. Expressed in coelomocyte; head; neurons; tail; and in male. label: flp-18 legacy_description: flp-18 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome, other than flp-21, that activates the solitary (215V) form of NPR-1 in Xenopus oocytes; in addition, FLP-18 can activated the social (215F) form of NPR-1 in pharyngeal assays; FLP-18 is expressed in the interneurons AVA, AIY and RIG, the motor neuron RIM and the pharyngeal neurons M2 and M3. merged_into: ~ name: class: gene highlight: description_all: - flp-18 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome, other - than flp-21, that activates the solitary (215V) form of NPR-1 in Xenopus oocytes; in addition, FLP-18 - can activated the social (215F) form of NPR-1 in pharyngeal assays; FLP-18 is expressed in the interneurons id: WBGene00001461 label: flp-18 other_names: - Y48D7A.2 - CELE_Y48D7A.2 - Y48D7A.2.1 - Y48D7A.2.2 - Y48D7A.2 - CE33736 taxonomy: c_elegans other_names: - Y48D7A.2 - CELE_Y48D7A.2 - Y48D7A.2.1 - Y48D7A.2.2 - Y48D7A.2 - CE33736 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001461 - allele: - class: variation id: WBVar00375770 label: gk152527 - class: variation id: WBVar00761494 label: gk677295 - class: variation id: WBVar00761430 label: gk503248 - class: variation id: WBVar00761498 label: gk325816 - class: variation id: WBVar00761469 label: gk718361 - class: variation id: WBVar00761491 label: gk711062 - class: variation id: WBVar00761429 label: gk854784 - class: variation id: WBVar00761502 label: gk475546 - class: variation id: WBVar00092851 label: ok1643 - class: variation id: WBVar00761492 label: gk449446 - class: variation id: WBVar00761461 label: gk380651 - class: variation id: WBVar00761483 label: gk604064 - class: variation id: WBVar00761426 label: gk845404 - class: variation id: WBVar00761460 label: gk839364 - class: variation id: WBVar00761420 label: gk453585 - class: variation id: WBVar00761410 label: gk473042 - class: variation id: WBVar00761474 label: gk413634 - class: variation id: WBVar02145110 label: tm7929 - class: variation id: WBVar00375768 label: gk152525 - class: variation id: WBVar00761464 label: gk351001 - class: variation id: WBVar00761443 label: gk324719 - class: variation id: WBVar00761439 label: gk328245 - class: variation id: WBVar00761428 label: gk558098 - class: variation id: WBVar00761415 label: gk578160 - class: variation id: WBVar00761473 label: gk836891 - class: variation id: WBVar00761478 label: gk737666 - class: variation id: WBVar00761424 label: gk731445 - class: variation id: WBVar00761475 label: gk428143 - class: variation id: WBVar00761418 label: gk632606 - class: variation id: WBVar00375763 label: gk152520 - class: variation id: WBVar00375773 label: gk152530 - class: variation id: WBVar00761459 label: gk515308 - class: variation id: WBVar01477879 label: gk942137 - class: variation id: WBVar01499512 label: gk963574 - class: variation id: WBVar02130611 label: h17569 - class: variation id: WBVar02151204 label: tm10845 - class: variation id: WBVar00375759 label: gk152516 - class: variation id: WBVar00761468 label: gk318165 - class: variation id: WBVar00761496 label: gk557609 - class: variation id: WBVar00761462 label: gk737082 - class: variation id: WBVar02148047 label: tm10267 - class: variation id: WBVar00761411 label: gk577625 - class: variation id: WBVar00761416 label: gk854166 - class: variation id: WBVar00761453 label: gk563909 - class: variation id: WBVar00761454 label: gk637209 - class: variation id: WBVar00375760 label: gk152517 - class: variation id: WBVar00761438 label: gk398619 - class: variation id: WBVar00761488 label: gk904411 - class: variation id: WBVar00375753 label: gk152510 - class: variation id: WBVar00761436 label: gk417493 - class: variation id: WBVar00761500 label: gk326674 - class: variation id: WBVar01492775 label: gk957038 - class: variation id: WBVar00761422 label: gk759059 - class: variation id: WBVar00761448 label: gk588729 - class: variation id: WBVar00375772 label: gk152529 - class: variation id: WBVar00375767 label: gk152524 - class: variation id: WBVar00761406 label: gk896630 - class: variation id: WBVar00142601 label: cxTi10645 - class: variation id: WBVar00375764 label: gk152521 - class: variation id: WBVar00375758 label: gk152515 - class: variation id: WBVar00761485 label: gk358971 - class: variation id: WBVar00761490 label: gk928257 - class: variation id: WBVar00761449 label: gk519944 - class: variation id: WBVar00375755 label: gk152512 - class: variation id: WBVar00761457 label: gk565655 - class: variation id: WBVar00761409 label: gk430640 - class: variation id: WBVar00761455 label: gk567665 - class: variation id: WBVar00375751 label: gk152508 - class: variation id: WBVar00761444 label: gk831345 - class: variation id: WBVar00761437 label: gk368785 - class: variation id: WBVar00761466 label: gk466588 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00375777 label: gk152534 - class: variation id: WBVar00375754 label: gk152511 - class: variation id: WBVar00761456 label: gk453586 - class: variation id: WBVar00761440 label: gk409306 - class: variation id: WBVar00761414 label: gk801335 - class: variation id: WBVar00761465 label: gk503249 - class: variation id: WBVar00761499 label: gk805172 - class: variation id: WBVar00761481 label: gk745320 - class: variation id: WBVar01477876 label: gk942134 - class: variation id: WBVar00761413 label: gk904108 - class: variation id: WBVar00761417 label: gk803609 - class: variation id: WBVar00761451 label: gk378002 - class: variation id: WBVar00761408 label: gk418753 - class: variation id: WBVar00375762 label: gk152519 - class: variation id: WBVar00761425 label: gk430259 - class: variation id: WBVar00761447 label: gk635554 - class: variation id: WBVar00761446 label: gk494535 - class: variation id: WBVar00375756 label: gk152513 - class: variation id: WBVar00761482 label: gk687996 - class: variation id: WBVar00375766 label: gk152523 - class: variation id: WBVar00761419 label: gk521629 - class: variation id: WBVar00375746 label: gk152503 - class: variation id: WBVar00375769 label: gk152526 - class: variation id: WBVar00375748 label: gk152505 - class: variation id: WBVar00761432 label: gk645235 - class: variation id: WBVar00761458 label: gk565656 - class: variation id: WBVar00761407 label: gk554651 - class: variation id: WBVar00375776 label: gk152533 - class: variation id: WBVar00761479 label: gk555524 - class: variation id: WBVar00761476 label: gk471147 - class: variation id: WBVar00761495 label: gk801336 - class: variation id: WBVar00761463 label: gk892659 - class: variation id: WBVar00761412 label: gk727214 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00761467 label: gk455285 - class: variation id: WBVar00761493 label: gk727215 - class: variation id: WBVar00761487 label: gk401318 - class: variation id: WBVar00761471 label: gk798031 - class: variation id: WBVar00375747 label: gk152504 - class: variation id: WBVar00761486 label: gk369934 - class: variation id: WBVar01477877 label: gk942135 - class: variation id: WBVar00375752 label: gk152509 - class: variation id: WBVar01498940 label: gk962682 - class: variation id: WBVar00375771 label: gk152528 - class: variation id: WBVar00761441 label: gk379245 - class: variation id: WBVar01489718 label: gk953981 - class: variation id: WBVar00375757 label: gk152514 - class: variation id: WBVar00761472 label: gk431274 - class: variation id: WBVar00375750 label: gk152507 - class: variation id: WBVar00761435 label: gk465586 - class: variation id: WBVar00375761 label: gk152518 - class: variation id: WBVar00761421 label: gk606975 - class: variation id: WBVar00761427 label: gk321111 - class: variation id: WBVar00761484 label: gk893915 - class: variation id: WBVar00375749 label: gk152506 - class: variation id: WBVar00761480 label: gk498866 - class: variation id: WBVar00761450 label: gk859073 - class: variation id: WBVar01477878 label: gk942136 - class: variation id: WBVar00761501 label: gk829377 - class: variation id: WBVar00375774 label: gk152531 - class: variation id: WBVar00092850 label: ok1642 - class: variation id: WBVar00761497 label: gk659144 - class: variation id: WBVar00761445 label: gk886579 - class: variation id: WBVar00761470 label: gk618235 - class: variation id: WBVar01499513 label: gk963575 - class: variation id: WBVar00761423 label: gk534054 - class: variation id: WBVar00761452 label: gk527612 - class: variation id: WBVar00761489 label: gk532709 - class: variation id: WBVar00375775 label: gk152532 - class: variation id: WBVar00761477 label: gk460346 - class: variation id: WBVar00761442 label: gk349338 - class: variation id: WBVar00761433 label: gk366722 - class: variation id: WBVar00375745 label: gk152502 - class: variation id: WBVar00262245 label: ttTI35752 - class: variation id: WBVar00761434 label: gk779609 - class: variation id: WBVar00375765 label: gk152522 - class: variation id: WBVar00761431 label: gk853480 - class: variation id: WBVar00276690 label: ok5066 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in peroxisome. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 18. Is an ortholog of human SZT2 (SZT2 subunit of KICSTOR complex). label: F54B3.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 18. id: WBGene00010013 label: F54B3.1 other_names: - F54B3.1 - CELE_F54B3.1 - F54B3.1a - F54B3.1a.1 - CE43180 - F54B3.1b - CE43308 - F54B3.1b.1 taxonomy: c_elegans other_names: - F54B3.1 - CELE_F54B3.1 - F54B3.1a - F54B3.1a.1 - CE43180 - F54B3.1b - CE43308 - F54B3.1b.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00010013 - allele: - class: variation id: WBVar02151809 label: tm11477 - class: variation id: WBVar01191500 label: gk655984 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar02140186 label: h5059 - class: variation id: WBVar00518567 label: gk295324 - class: variation id: WBVar01191499 label: gk327690 - class: variation id: WBVar00518566 label: gk295323 - class: variation id: WBVar00518568 label: gk295325 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar01499887 label: gk964028 - class: variation id: WBVar01191502 label: gk709689 - class: variation id: WBVar01499888 label: gk964029 - class: variation id: WBVar01499710 label: gk963810 - class: variation id: WBVar01191501 label: gk881162 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in several structures, including Caaaaa; Caaaap; Caaapa; Caaapp; and Caappd based on single-cell RNA-seq studies. Is affected by mrps-5 and daf-18 based on RNA-seq studies. label: C49F5.13 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by mrps-5 and daf-18 based on RNA-seq studies. id: WBGene00268215 label: C49F5.13 other_names: - C49F5.13 - CELE_C49F5.13 - C49F5.13 - CE51221 - C49F5.13.1 taxonomy: c_elegans other_names: - C49F5.13 - CELE_C49F5.13 - C49F5.13 - CE51221 - C49F5.13.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00268215 - allele: - class: variation id: WBVar01117043 label: gk579598 - class: variation id: WBVar01117041 label: gk358436 - class: variation id: WBVar01117023 label: gk909876 - class: variation id: WBVar01117014 label: gk763422 - class: variation id: WBVar00493645 label: gk270402 - class: variation id: WBVar01117000 label: gk367742 - class: variation id: WBVar01117012 label: gk557370 - class: variation id: WBVar00299087 label: otn2266 - class: variation id: WBVar00493642 label: gk270399 - class: variation id: WBVar01117039 label: gk505664 - class: variation id: WBVar00493643 label: gk270400 - class: variation id: WBVar01117026 label: gk323524 - class: variation id: WBVar00254043 label: ttTi3345 - class: variation id: WBVar01116996 label: gk674113 - class: variation id: WBVar01116995 label: gk814305 - class: variation id: WBVar00493656 label: gk270413 - class: variation id: WBVar00493657 label: gk270414 - class: variation id: WBVar01117015 label: gk758797 - class: variation id: WBVar01117020 label: gk875427 - class: variation id: WBVar00493658 label: gk270415 - class: variation id: WBVar00493649 label: gk270406 - class: variation id: WBVar00493641 label: gk270398 - class: variation id: WBVar00493646 label: gk270403 - class: variation id: WBVar01117016 label: gk586729 - class: variation id: WBVar01117027 label: gk744390 - class: variation id: WBVar01116999 label: gk735012 - class: variation id: WBVar00302349 label: otn5528 - class: variation id: WBVar00493652 label: gk270409 - class: variation id: WBVar01116998 label: gk358038 - class: variation id: WBVar01498638 label: gk963652 - class: variation id: WBVar01117005 label: gk435870 - class: variation id: WBVar01117036 label: gk429871 - class: variation id: WBVar01117013 label: gk329206 - class: variation id: WBVar01117032 label: gk728711 - class: variation id: WBVar01117028 label: gk347561 - class: variation id: WBVar01117042 label: gk819686 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar01117001 label: gk764235 - class: variation id: WBVar01117018 label: gk566293 - class: variation id: WBVar01117024 label: gk323523 - class: variation id: WBVar01117006 label: gk429071 - class: variation id: WBVar01117035 label: gk836051 - class: variation id: WBVar01117019 label: gk418636 - class: variation id: WBVar01117044 label: gk636561 - class: variation id: WBVar01117033 label: gk766370 - class: variation id: WBVar01117031 label: gk744391 - class: variation id: WBVar01116997 label: gk713995 - class: variation id: WBVar00493654 label: gk270411 - class: variation id: WBVar01117037 label: gk915975 - class: variation id: WBVar00493647 label: gk270404 - class: variation id: WBVar00493651 label: gk270408 - class: variation id: WBVar01117030 label: gk341891 - class: variation id: WBVar00493644 label: gk270401 - class: variation id: WBVar01117004 label: gk480730 - class: variation id: WBVar01117029 label: gk766796 - class: variation id: WBVar00493648 label: gk270405 - class: variation id: WBVar01117022 label: gk427116 - class: variation id: WBVar01117038 label: gk787499 - class: variation id: WBVar01117021 label: gk520675 - class: variation id: WBVar01117007 label: gk377875 - class: variation id: WBVar01117017 label: gk834074 - class: variation id: WBVar00493655 label: gk270412 - class: variation id: WBVar01117025 label: gk872174 - class: variation id: WBVar01117010 label: gk557369 - class: variation id: WBVar00493650 label: gk270407 - class: variation id: WBVar01117002 label: gk467919 - class: variation id: WBVar01117003 label: gk463111 - class: variation id: WBVar01117009 label: gk468481 - class: variation id: WBVar01117040 label: gk859295 - class: variation id: WBVar01117034 label: gk545618 - class: variation id: WBVar00493653 label: gk270410 - class: variation id: WBVar01117008 label: gk914844 - class: variation id: WBVar01117011 label: gk852279 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Is an ortholog of human SLC18B1 (solute carrier family 18 member B1). label: vpat-1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human SLC18B1 (solute carrier family 18 member B1). id: WBGene00018860 label: vpat-1 other_names: - F55A4.8 - CELE_F55A4.8 - F55A4.8c - CE41818 - F55A4.8b.1 - F55A4.8d - F55A4.8a - F55A4.8b - F55A4.8c.1 - F55A4.8d.1 - CE31182 - CE41819 - CE41817 - F55A4.8a.1 taxonomy: c_elegans other_names: - F55A4.8 - CELE_F55A4.8 - F55A4.8c - CE41818 - F55A4.8b.1 - F55A4.8d - F55A4.8a - F55A4.8b - F55A4.8c.1 - F55A4.8d.1 - CE31182 - CE41819 - CE41817 - F55A4.8a.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00018860 - allele: - class: variation id: WBVar01090191 label: gk314919 - class: variation id: WBVar01499446 label: gk963489 - class: variation id: WBVar01499709 label: gk963809 - class: variation id: WBVar01090190 label: gk853816 - class: variation id: WBVar01498957 label: gk962704 - class: variation id: WBVar01498549 label: gk963304 - class: variation id: WBVar01499566 label: gk963637 - class: variation id: WBVar01498290 label: gk962630 - class: variation id: WBVar01499004 label: gk962779 - class: variation id: WBVar00484590 label: gk261347 - class: variation id: WBVar01499299 label: gk963271 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-2; eat-2; and daf-18 based on RNA-seq and microarray studies. Is affected by mianserin; Zidovudine; and cadmium based on RNA-seq studies. label: C06H5.14 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-2; eat-2; and daf-18 based on RNA-seq and microarray studies id: WBGene00219447 label: C06H5.14 other_names: - C06H5.14 - CELE_C06H5.14 - C06H5.14.1 - C06H5.14 - CE47535 taxonomy: c_elegans other_names: - C06H5.14 - CELE_C06H5.14 - C06H5.14.1 - C06H5.14 - CE47535 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00219447 - allele: - class: variation id: WBVar00710300 label: gk822609 - class: variation id: WBVar01500106 label: gk964317 - class: variation id: WBVar00710299 label: gk852803 - class: variation id: WBVar01499702 label: gk963801 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in AVE and neurons based on tiling array studies. Is affected by several genes including daf-2; daf-18; and unc-70 based on tiling array; RNA-seq; and microarray studies. label: C33C12.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-2; daf-18; and unc-70 based on tiling array; RNA-seq; and id: WBGene00016334 label: C33C12.1 other_names: - C33C12.1 - CELE_C33C12.1 - C33C12.1.1 - CE53851 - C33C12.1 taxonomy: c_elegans other_names: - C33C12.1 - CELE_C33C12.1 - C33C12.1.1 - CE53851 - C33C12.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00016334 - allele: - class: variation id: WBVar00929529 label: gk492178 - class: variation id: WBVar00431387 label: gk208144 - class: variation id: WBVar00929523 label: gk610386 - class: variation id: WBVar00929531 label: gk659953 - class: variation id: WBVar00929528 label: gk789106 - class: variation id: WBVar00929526 label: gk313288 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00929532 label: gk740893 - class: variation id: WBVar00431388 label: gk208145 - class: variation id: WBVar00929522 label: gk896765 - class: variation id: WBVar01498928 label: gk962666 - class: variation id: WBVar00929525 label: gk824908 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00929536 label: gk666110 - class: variation id: WBVar00929535 label: gk772971 - class: variation id: WBVar00929524 label: gk636829 - class: variation id: WBVar00431391 label: gk208148 - class: variation id: WBVar00929527 label: gk462015 - class: variation id: WBVar00431392 label: gk208149 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00431390 label: gk208147 - class: variation id: WBVar00431386 label: gk208143 - class: variation id: WBVar00929530 label: gk713838 - class: variation id: WBVar00929533 label: gk677395 - class: variation id: WBVar00929521 label: gk438237 - class: variation id: WBVar00929534 label: gk510816 - class: variation id: WBVar00431389 label: gk208146 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Located in nucleus. Human ortholog(s) of this gene implicated in adenocarcinoma (multiple) and breast cancer. Is an ortholog of human SLC22A18 (solute carrier family 22 member 18). label: C53B4.3 legacy_description: C53B4.3 is orthologous to the human gene, Solute Carrier Family 22 (Organic Cation Transporter), Member 18, referred to as SLC22A18; C53B4.3 is expressed in body wall muscle based on large-scale GFP studies. merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human SLC22A18 (solute carrier family 22 member 18). - C53B4.3 is orthologous to the human gene, Solute Carrier Family 22 (Organic Cation Transporter), Member 18 id: WBGene00008273 label: C53B4.3 other_names: - C53B4.3 - CELE_C53B4.3 - C53B4.3.2 - CE37333 - C53B4.3.1 - C53B4.3 taxonomy: c_elegans other_names: - C53B4.3 - CELE_C53B4.3 - C53B4.3.2 - CE37333 - C53B4.3.1 - C53B4.3 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00008273 - allele: - class: variation id: WBVar01032191 label: gk746507 - class: variation id: WBVar00465045 label: gk241802 - class: variation id: WBVar01032208 label: gk493273 - class: variation id: WBVar00465044 label: gk241801 - class: variation id: WBVar00253192 label: ttTi395 - class: variation id: WBVar01497185 label: gk961448 - class: variation id: WBVar01032197 label: gk582608 - class: variation id: WBVar00465046 label: gk241803 - class: variation id: WBVar01032193 label: gk705507 - class: variation id: WBVar01499056 label: gk962860 - class: variation id: WBVar00465043 label: gk241800 - class: variation id: WBVar01032196 label: gk499072 - class: variation id: WBVar01032203 label: gk909823 - class: variation id: WBVar01032205 label: gk447887 - class: variation id: WBVar00145784 label: gk378 - class: variation id: WBVar01032198 label: gk788091 - class: variation id: WBVar01032201 label: gk447068 - class: variation id: WBVar01032206 label: gk774110 - class: variation id: WBVar01499903 label: gk964052 - class: variation id: WBVar02148185 label: tm10425 - class: variation id: WBVar01032207 label: gk764119 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01032199 label: gk564205 - class: variation id: WBVar01032200 label: gk466280 - class: variation id: WBVar01032195 label: gk751552 - class: variation id: WBVar00465042 label: gk241799 - class: variation id: WBVar01032202 label: gk820195 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01032194 label: gk818264 - class: variation id: WBVar01032204 label: gk447069 - class: variation id: WBVar01032192 label: gk478129 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables phosphatidylinositol phosphate binding activity. Involved in several processes, including determination of adult lifespan; gamete generation; and xenophagy. Acts upstream of or within with a positive effect on plasma membrane repair. Located in phagocytic vesicle. Expressed in several structures, including head and tail. Used to study Huntington's disease. Is an ortholog of human WIPI2 (WD repeat domain, phosphoinositide interacting 2). label: atg-18 legacy_description: atg-18 encodes, by alternative splicing, two isoforms of a WD40 repeat-containing protein orthologous to the autophagic budding yeast protein Atg18p, and to human WIPI1 (OMIM:609224) and WIPI2 (OMIM:609225); ATG-18 activity is essential for normal dauer morphogenesis and autophagy in daf-2 mutant animals; ATG-18 is expressed in larval and adult pharynx, bodywall muscle, hypodermis, seam cells, and neurons, and in larval intestine; in mass RNAi assays, ATG-18 is required for normally rapid growth, and is weakly required for the viability of cup-5(ar465) mutants. merged_into: ~ name: class: gene highlight: description_all: - atg-18 encodes, by alternative splicing, two isoforms of a WD40 repeat-containing protein orthologous - autophagic budding yeast protein Atg18p, and to human WIPI1 (OMIM:609224) and WIPI2 (OMIM:609225); ATG-18 - activity is essential for normal dauer morphogenesis and autophagy in daf-2 mutant animals; ATG-18 is - bodywall muscle, hypodermis, seam cells, and neurons, and in larval intestine; in mass RNAi assays, ATG-18 id: WBGene00018294 label: atg-18 other_names: - F41E6.13 - tag-283 - CELE_F41E6.13 - atgr-18 - F41E6.13a - F41E6.13b.1 - F41E6.13a.1 - CE30784 - CE10268 - F41E6.13b taxonomy: c_elegans other_names: - F41E6.13 - tag-283 - CELE_F41E6.13 - atgr-18 - F41E6.13a - F41E6.13b.1 - F41E6.13a.1 - CE30784 - CE10268 - F41E6.13b page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00018294 - allele: - class: variation id: WBVar00355001 label: gk131758 - class: variation id: WBVar01500106 label: gk964317 - class: variation id: WBVar00699246 label: gk381428 - class: variation id: WBVar00699257 label: gk759011 - class: variation id: WBVar02147538 label: ot720 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00265667 label: ttTi50840 - class: variation id: WBVar00699235 label: gk378648 - class: variation id: WBVar00143856 label: e1245 - class: variation id: WBVar00699250 label: gk825218 - class: variation id: WBVar00699265 label: gk666001 - class: variation id: WBVar00699239 label: gk550863 - class: variation id: WBVar00699248 label: gk770184 - class: variation id: WBVar00699234 label: gk806344 - class: variation id: WBVar00354997 label: gk131754 - class: variation id: WBVar00242576 label: sa423 - class: variation id: WBVar00699255 label: gk887100 - class: variation id: WBVar00699266 label: gk461752 - class: variation id: WBVar00699264 label: gk875913 - class: variation id: WBVar00354998 label: gk131755 - class: variation id: WBVar00699258 label: gk852032 - class: variation id: WBVar00699243 label: gk554142 - class: variation id: WBVar00699237 label: gk476437 - class: variation id: WBVar00699236 label: gk399598 - class: variation id: WBVar00699259 label: gk764749 - class: variation id: WBVar00354999 label: gk131756 - class: variation id: WBVar00699244 label: gk474542 - class: variation id: WBVar00699256 label: gk845350 - class: variation id: WBVar00699245 label: gk686534 - class: variation id: WBVar00305070 label: otn8249 - class: variation id: WBVar00699242 label: gk829311 - class: variation id: WBVar00355000 label: gk131757 - class: variation id: WBVar00699247 label: gk865242 - class: variation id: WBVar02150480 label: tm12972 - class: variation id: WBVar00699238 label: gk854096 - class: variation id: WBVar00699267 label: gk592466 - class: variation id: WBVar01476839 label: gk941096 - class: variation id: WBVar00263050 label: ttTi37745 - class: variation id: WBVar00144787 label: e2376 - class: variation id: WBVar00699260 label: gk522151 - class: variation id: WBVar02147541 label: ot788 - class: variation id: WBVar00699251 label: gk396730 - class: variation id: WBVar02147543 label: ot863 - class: variation id: WBVar00699253 label: gk801243 - class: variation id: WBVar00699263 label: gk872869 - class: variation id: WBVar00699240 label: gk380173 - class: variation id: WBVar02148337 label: tm10597 - class: variation id: WBVar00242575 label: sa417 - class: variation id: WBVar00354996 label: gk131753 - class: variation id: WBVar00699261 label: gk677848 - class: variation id: WBVar00699252 label: gk831271 - class: variation id: WBVar00699249 label: gk704678 - class: variation id: WBVar00699241 label: gk592068 - class: variation id: WBVar00144812 label: e2410 - class: variation id: WBVar00699254 label: gk782147 - class: variation id: WBVar00699262 label: gk692851 - class: variation id: WBVar00242579 label: sa473 - class: variation id: WBVar00355002 label: gk131759 - class: variation id: WBVar00699268 label: gk625078 - class: variation id: WBVar00249505 label: tm460 - class: variation id: WBVar00355003 label: gk131760 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and post-embryonic hindgut morphogenesis. Located in nucleus. Expressed in several structures, including B.a; B.p; neurons; proctodeum; and rectal epithelial cell. Human ortholog(s) of this gene implicated in atrial heart septal defect 4; tetralogy of Fallot; and ventricular septal defect. Is an ortholog of human TBX20 (T-box transcription factor 20). label: mab-9 legacy_description: mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 mutations also affect backward locomotion as a result of motor neuron axon guidance defects; MAB-9 localizes to the nucleus of B and F and their descendents during development and is also detected in the nuclei of all embryonically derived motor neurons. merged_into: ~ name: class: gene highlight: description_all: - mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid - T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail - spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab - and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab - -9 mutations also affect backward locomotion as a result of motor neuron axon guidance defects; MAB-9 id: WBGene00003106 label: mab-9 other_names: - T27A1.6 - Ce-tbx-12 - CELE_T27A1.6 - tbx-12 - T27A1.6.1 - CE24016 - T27A1.6 taxonomy: c_elegans other_names: - T27A1.6 - Ce-tbx-12 - CELE_T27A1.6 - tbx-12 - T27A1.6.1 - CE24016 - T27A1.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003106 - allele: - class: variation id: WBVar00615201 label: gk764704 - class: variation id: WBVar00615209 label: gk479148 - class: variation id: WBVar00326784 label: gk103541 - class: variation id: WBVar00615212 label: gk362131 - class: variation id: WBVar00326783 label: gk103540 - class: variation id: WBVar00615216 label: gk628042 - class: variation id: WBVar00326785 label: gk103542 - class: variation id: WBVar01474847 label: gk939101 - class: variation id: WBVar00615205 label: gk502505 - class: variation id: WBVar00326789 label: gk103546 - class: variation id: WBVar01499559 label: gk963630 - class: variation id: WBVar01499619 label: gk963701 - class: variation id: WBVar00615221 label: gk763019 - class: variation id: WBVar00326782 label: gk103539 - class: variation id: WBVar00296464 label: jj4 - class: variation id: WBVar00252381 label: tm3773 - class: variation id: WBVar00615224 label: gk745670 - class: variation id: WBVar00615214 label: gk519846 - class: variation id: WBVar01490941 label: gk955204 - class: variation id: WBVar00615204 label: gk399961 - class: variation id: WBVar00326786 label: gk103543 - class: variation id: WBVar00326781 label: gk103538 - class: variation id: WBVar00615225 label: gk524472 - class: variation id: WBVar02126374 label: h8413 - class: variation id: WBVar00615222 label: gk570712 - class: variation id: WBVar02126371 label: h15532 - class: variation id: WBVar00263789 label: ttTi40343 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar00615218 label: gk750274 - class: variation id: WBVar00615206 label: gk650126 - class: variation id: WBVar00615220 label: gk499212 - class: variation id: WBVar01490942 label: gk955205 - class: variation id: WBVar00615210 label: gk347646 - class: variation id: WBVar00615208 label: gk854648 - class: variation id: WBVar00615198 label: gk392628 - class: variation id: WBVar00326780 label: gk103537 - class: variation id: WBVar00615200 label: gk834173 - class: variation id: WBVar02126375 label: h5101 - class: variation id: WBVar00615213 label: gk396145 - class: variation id: WBVar00326790 label: gk103547 - class: variation id: WBVar00615219 label: gk793653 - class: variation id: WBVar02157676 label: tk81 - class: variation id: WBVar00326788 label: gk103545 - class: variation id: WBVar00615207 label: gk469137 - class: variation id: WBVar00615199 label: gk629361 - class: variation id: WBVar00615211 label: gk325052 - class: variation id: WBVar00326779 label: gk103536 - class: variation id: WBVar02126373 label: h12012 - class: variation id: WBVar00615217 label: gk669362 - class: variation id: WBVar02126372 label: h15533 - class: variation id: WBVar00615223 label: gk882358 - class: variation id: WBVar00615203 label: gk529541 - class: variation id: WBVar01474848 label: gk939102 - class: variation id: WBVar00615202 label: gk325712 - class: variation id: WBVar00615197 label: gk508350 - class: variation id: WBVar00615215 label: gk456990 - class: variation id: WBVar00326787 label: gk103544 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable coreceptor activity. Involved in several processes, including mesodermal cell fate specification; regulation of BMP signaling pathway; and regulation of dauer larval development. Located in plasma membrane. Part of receptor complex. Expressed in hypodermis and intestine. Human ortholog(s) of this gene implicated in hemochromatosis type 2A and multiple sclerosis. Is an ortholog of human HJV (hemojuvelin BMP co-receptor) and RGMA (repulsive guidance molecule BMP co-receptor a). label: drag-1 legacy_description: drag-1 encodes the C. elegans homolog of a putative GPI-anchor protein of the RGM family, a membrane associated protein that functions as co-receptor in the the Sma/Mab pathway; drag-1 mutants exhibit a subset of phenotypes seen in mutants in the Sma/Mab pathway like smaller than wildtype worm phenotype throughout the larval development, the males could mate and have no male tail patterning defects; drag-1 genetically interacts with daf-7 and daf-1 mutants in dauer pathway; drag-1 likely acts upstream of lon-1, but in parallel to lon-2 and dbl-1 suggesting that it is functioning at the ligands-receptor level in the Sma/Mab pathway to regulate body size; Drag-1 functions in the same cells as the Sma-9 and Sma/Mab receptors and SMAD proteins to regulate body size; DRAG-1 is not only present but also functions at the cell membrane; DRAG-1 is a positive regulator of the sma/Mab pathway; drag-1p::gfp is expressed in pharyngeal, hypodermal and intestinal cells as like sma-6 in hermaphrodites, but not in male tail cells. merged_into: ~ name: class: gene highlight: description_all: - protein of the RGM family, a membrane associated protein that functions as co-receptor in the the Sma/Mab - pathway; drag-1 mutants exhibit a subset of phenotypes seen in mutants in the Sma/Mab pathway like smaller - parallel to lon-2 and dbl-1 suggesting that it is functioning at the ligands-receptor level in the Sma/Mab - pathway to regulate body size; Drag-1 functions in the same cells as the Sma-9 and Sma/Mab receptors - not only present but also functions at the cell membrane; DRAG-1 is a positive regulator of the sma/Mab id: WBGene00022154 label: drag-1 other_names: - Y71G12B.16 - CELE_Y71G12B.16 - CE45612 - Y71G12B.16 - Y71G12B.16.1 taxonomy: c_elegans other_names: - Y71G12B.16 - CELE_Y71G12B.16 - CE45612 - Y71G12B.16 - Y71G12B.16.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00022154 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Cbr-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00037527 label: Cbr-mab-21 other_names: - CBG18030 - CBG_18030 - CBG18030 - CBP37045 - CBG18030.1 taxonomy: c_briggsae other_names: - CBG18030 - CBG_18030 - CBG18030 - CBP37045 - CBG18030.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00037527 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Ovo-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00244454 label: Ovo-mab-21 other_names: - OVOC7645 - OVP01753 - OVOC7645.1 - OVOC7645 taxonomy: o_volvulus other_names: - OVOC7645 - OVP01753 - OVOC7645.1 - OVOC7645 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00244454 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: SRAE_2000017800 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00260368 label: SRAE_2000017800 other_names: - SRAE_2000017800 - SR00552 - SRAE_2000017800.1 - SRP04646 - SRAE_2000017800 taxonomy: s_ratti other_names: - SRAE_2000017800 - SR00552 - SRAE_2000017800.1 - SRP04646 - SRAE_2000017800 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00260368 - allele: - class: variation id: WBVar01120200 label: gk827650 - class: variation id: WBVar00494715 label: gk271472 - class: variation id: WBVar01120201 label: gk938272 - class: variation id: WBVar01500203 label: gk964445 - class: variation id: WBVar01500202 label: gk964444 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar00494714 label: gk271471 - class: variation id: WBVar01498221 label: gk962484 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-18; kri-1; and unc-70 based on RNA-seq studies. Is affected by four chemicals including Zidovudine; metformin; and Sirolimus based on RNA-seq studies. label: D1005.10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-18; kri-1; and unc-70 based on RNA-seq studies. id: WBGene00206384 label: D1005.10 other_names: - D1005.10 - CELE_D1005.10 - CE45801 - D1005.10 - D1005.10.1 taxonomy: c_elegans other_names: - D1005.10 - CELE_D1005.10 - CE45801 - D1005.10 - D1005.10.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00206384 - allele: - class: variation id: WBVar00820282 label: gk793752 - class: variation id: WBVar00820289 label: gk656694 - class: variation id: WBVar00820286 label: gk595035 - class: variation id: WBVar00820285 label: gk768552 - class: variation id: WBVar00820287 label: gk843875 - class: variation id: WBVar00820283 label: gk807468 - class: variation id: WBVar00820284 label: gk699353 - class: variation id: WBVar00820288 label: gk593276 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of human SAP18 (Sin3A associated protein 18). label: C16C10.4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human SAP18 (Sin3A associated protein 18). id: WBGene00007625 label: C16C10.4 other_names: - C16C10.4 - CELE_C16C10.4 - C16C10.4 - CE01495 - C16C10.4.1 - C16C10.4.2 taxonomy: c_elegans other_names: - C16C10.4 - CELE_C16C10.4 - C16C10.4 - CE01495 - C16C10.4.1 - C16C10.4.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007625 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Ppa-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00203478 label: Ppa-mab-21 other_names: - PPA30611 - UMM-S50-31.33 - PPA30611.1 - PP68765 - PPA30611 taxonomy: p_pacificus other_names: - PPA30611 - UMM-S50-31.33 - PPA30611.1 - PP68765 - PPA30611 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00203478 - allele: - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar01499204 label: gk963095 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar01499739 label: gk963849 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-16; daf-18; and rrf-1 based on RNA-seq and microarray studies. Is affected by five chemicals including cadmium; Colistin; and 2 based on microarray studies. label: clec-16 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; daf-18; and rrf-1 based on RNA-seq and microarray studies id: WBGene00011585 label: clec-16 other_names: - T07D10.5 - CELE_T07D10.5 - T07D10.5 taxonomy: c_elegans other_names: - T07D10.5 - CELE_T07D10.5 - T07D10.5 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00011585 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Cre-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00061744 label: Cre-mab-21 other_names: - CRE20348 - cr01.sctg26.wum.118 - RP27650 - CRE20348 - CRE20348.1 taxonomy: c_remanei other_names: - CRE20348 - cr01.sctg26.wum.118 - RP27650 - CRE20348 - CRE20348.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00061744 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: TMUE_2000010211 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00292712 label: TMUE_2000010211 other_names: - TMUE_2000010211 - TMUE_s0110002600 - TMUE_2000010211 - TMP09195 - TMUE_2000010211.1 taxonomy: t_muris other_names: - TMUE_2000010211 - TMUE_s0110002600 - TMUE_2000010211 - TMP09195 - TMUE_2000010211.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00292712 - allele: - class: variation id: WBVar01019720 label: gk798756 - class: variation id: WBVar01019716 label: gk331085 - class: variation id: WBVar01019725 label: gk540885 - class: variation id: WBVar01019718 label: gk361624 - class: variation id: WBVar00317536 label: tm2215 - class: variation id: WBVar01019712 label: gk721659 - class: variation id: WBVar01499173 label: gk963041 - class: variation id: WBVar01019715 label: gk926584 - class: variation id: WBVar01019717 label: gk379708 - class: variation id: WBVar00460981 label: gk237738 - class: variation id: WBVar00092757 label: ok1546 - class: variation id: WBVar01019724 label: gk681781 - class: variation id: WBVar01499496 label: gk963553 - class: variation id: WBVar01019721 label: gk758169 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01500066 label: gk964259 - class: variation id: WBVar01019726 label: gk537711 - class: variation id: WBVar01019723 label: gk418341 - class: variation id: WBVar01019713 label: gk526033 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01499740 label: gk963850 - class: variation id: WBVar00460980 label: gk237737 - class: variation id: WBVar01019711 label: gk518343 - class: variation id: WBVar01019719 label: gk443728 - class: variation id: WBVar01019722 label: gk650516 - class: variation id: WBVar01499174 label: gk963042 - class: variation id: WBVar00460979 label: gk237736 - class: variation id: WBVar01019714 label: gk523387 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to be located in endoplasmic reticulum. Predicted to be part of SNARE complex. Is an ortholog of human STX18 (syntaxin 18). label: syx-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human STX18 (syntaxin 18). id: WBGene00020425 label: syx-18 other_names: - T10H9.3 - CELE_T10H9.3 - CE18251 - T10H9.3.1 - T10H9.3 taxonomy: c_elegans other_names: - T10H9.3 - CELE_T10H9.3 - CE18251 - T10H9.3.1 - T10H9.3 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00020425 - allele: - class: variation id: WBVar01499525 label: gk963588 - class: variation id: WBVar01083587 label: gk435118 - class: variation id: WBVar01083578 label: gk460078 - class: variation id: WBVar01083583 label: gk620754 - class: variation id: WBVar01499524 label: gk963587 - class: variation id: WBVar00482381 label: gk259138 - class: variation id: WBVar02146755 label: tm8492 - class: variation id: WBVar01498549 label: gk963304 - class: variation id: WBVar01498290 label: gk962630 - class: variation id: WBVar01083579 label: gk576279 - class: variation id: WBVar01083577 label: gk829763 - class: variation id: WBVar01083585 label: gk580860 - class: variation id: WBVar01083582 label: gk370124 - class: variation id: WBVar01499446 label: gk963489 - class: variation id: WBVar01083576 label: gk637866 - class: variation id: WBVar01083581 label: gk372786 - class: variation id: WBVar01498710 label: gk964050 - class: variation id: WBVar01495943 label: gk960206 - class: variation id: WBVar00482380 label: gk259137 - class: variation id: WBVar01083580 label: gk770046 - class: variation id: WBVar01083586 label: gk805393 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01083584 label: gk623861 - class: variation id: WBVar01083588 label: gk879930 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-2; daf-18; and unc-30 based on RNA-seq and microarray studies. Is affected by five chemicals including Alovudine; Rifampin; and Psoralens based on RNA-seq studies. label: Y102A5C.35 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-2; daf-18; and unc-30 based on RNA-seq and microarray studies id: WBGene00044220 label: Y102A5C.35 other_names: - Y102A5C.35 - CELE_Y102A5C.35 - Y102A5C.35 taxonomy: c_elegans other_names: - Y102A5C.35 - CELE_Y102A5C.35 - Y102A5C.35 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00044220 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain; Neurobeachin-like, DUF1088; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Cjp-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain; Neurobeachin-like, DUF1088" - ; and Mab-21 protein nucleotidyltransferase domain. - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00135199 label: Cjp-mab-21 other_names: - CJA15995 - Cjp-sel-2 - CJA15995a.1 - CJA15995b - JA58724 - CJA15995b.1 - JA60742 - CJA15995a taxonomy: c_japonica other_names: - CJA15995 - Cjp-sel-2 - CJA15995a.1 - CJA15995b - JA58724 - CJA15995b.1 - JA60742 - CJA15995a page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00135199 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Cbn-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain; Protein 21-like 2; and Mab" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00143144 label: Cbn-mab-21 other_names: - CBN04419 - CBN04419 - CBN04419 - CN07136 - CBN04419.1 taxonomy: c_brenneri other_names: - CBN04419 - CBN04419 - CBN04419 - CN07136 - CBN04419.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00143144 - allele: - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar01499788 label: gk963906 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00093309 label: ok2130 - class: variation id: WBVar01498302 label: gk962676 - class: variation id: WBVar00672595 label: gk709282 - class: variation id: WBVar01498539 label: gk963278 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including sir-2.1; clk-1; and daf-18 based on microarray and RNA-seq studies. Is affected by Ethanol; methylmercury hydroxide; and resveratrol based on RNA-seq and microarray studies. label: ZK1025.5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including sir-2.1; clk-1; and daf-18 based on microarray and RNA-seq studies id: WBGene00014185 label: ZK1025.5 other_names: - ZK1025.5 - CELE_ZK1025.5 - ZK1025.5 taxonomy: c_elegans other_names: - ZK1025.5 - CELE_ZK1025.5 - ZK1025.5 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00014185 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18 and Y57G11C.18. label: CRE07170 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18 and Y57G11C.18. id: WBGene00080356 label: CRE07170 other_names: - CRE07170 - RP50223 - CRE07170.1 - CRE07170 taxonomy: c_remanei other_names: - CRE07170 - RP50223 - CRE07170.1 - CRE07170 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00080356 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18 and Y57G11C.18. label: CRE08614 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18 and Y57G11C.18. id: WBGene00075448 label: CRE08614 other_names: - CRE08614 - cr01.sctg2396.wum.1 - CRE08614.1 - CRE08614 - RP29709 taxonomy: c_remanei other_names: - CRE08614 - cr01.sctg2396.wum.1 - CRE08614.1 - CRE08614 - RP29709 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00075448 - allele: - class: variation id: WBVar00801304 label: gk887146 - class: variation id: WBVar00250998 label: tm2052 - class: variation id: WBVar00093210 label: ok2020 - class: variation id: WBVar00389230 label: gk165987 - class: variation id: WBVar00801314 label: gk515960 - class: variation id: WBVar00801308 label: gk813958 - class: variation id: WBVar01498832 label: gk962532 - class: variation id: WBVar00801306 label: gk384668 - class: variation id: WBVar00801305 label: gk927030 - class: variation id: WBVar00251060 label: tm2121 - class: variation id: WBVar02131454 label: h16913 - class: variation id: WBVar01500082 label: gk964281 - class: variation id: WBVar00801309 label: gk833875 - class: variation id: WBVar00801310 label: gk347297 - class: variation id: WBVar00801312 label: gk421337 - class: variation id: WBVar00801311 label: gk711701 - class: variation id: WBVar02131455 label: h10885 - class: variation id: WBVar01499552 label: gk963623 - class: variation id: WBVar00801303 label: gk804159 - class: variation id: WBVar00093085 label: ok1890 - class: variation id: WBVar00801313 label: gk374111 - class: variation id: WBVar00801307 label: gk314359 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable GTPase activity. Predicted to be involved in intracellular protein transport and lipid droplet organization. Predicted to be located in Golgi apparatus. Human ortholog(s) of this gene implicated in Warburg micro syndrome 3. Is an ortholog of human RAB18 (RAB18, member RAS oncogene family). label: rab-18 legacy_description: rab-18 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion, and vesicular trafficking events; the precise biological role and expression pattern of rab-18 are not yet known. merged_into: ~ name: class: gene highlight: description_all: - rab-18 encodes a small GTPase homologous to the Rab GTPases that function in endocytosis, membrane fusion - ", and vesicular trafficking events; the precise biological role and expression pattern of rab-18 are" id: WBGene00004277 label: rab-18 other_names: - Y92C3B.3 - CELE_Y92C3B.3 - pra-1 - Y92C3B.3a.1 - Y92C3B.3b.2 - Y92C3B.3b.1 - CE34438 - Y92C3B.3a - Y92C3B.3b - CE27340 - Y92C3B.3a.2 taxonomy: c_elegans other_names: - Y92C3B.3 - CELE_Y92C3B.3 - pra-1 - Y92C3B.3a.1 - Y92C3B.3b.2 - Y92C3B.3b.1 - CE34438 - Y92C3B.3a - Y92C3B.3b - CE27340 - Y92C3B.3a.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004277 - allele: - class: variation id: WBVar01136722 label: gk595792 - class: variation id: WBVar00500048 label: gk276805 - class: variation id: WBVar00088899 label: mg57 - class: variation id: WBVar01136670 label: gk533008 - class: variation id: WBVar01136698 label: gk658932 - class: variation id: WBVar00500051 label: gk276808 - class: variation id: WBVar01136747 label: gk339880 - class: variation id: WBVar01136678 label: gk328946 - class: variation id: WBVar02139082 label: h14463 - class: variation id: WBVar00500047 label: gk276804 - class: variation id: WBVar01136693 label: gk829859 - class: variation id: WBVar00500027 label: gk276784 - class: variation id: WBVar01136684 label: gk890791 - class: variation id: WBVar01136743 label: gk831783 - class: variation id: WBVar00500049 label: gk276806 - class: variation id: WBVar00092351 label: ok1082 - class: variation id: WBVar01136751 label: gk334031 - class: variation id: WBVar00500040 label: gk276797 - class: variation id: WBVar01136667 label: gk636581 - class: variation id: WBVar00500044 label: gk276801 - class: variation id: WBVar01136701 label: gk836622 - class: variation id: WBVar01136682 label: gk329775 - class: variation id: WBVar01136717 label: gk737436 - class: variation id: WBVar01136672 label: gk683688 - class: variation id: WBVar01136683 label: gk398057 - class: variation id: WBVar01136732 label: gk751681 - class: variation id: WBVar00500043 label: gk276800 - class: variation id: WBVar01136721 label: gk739302 - class: variation id: WBVar01136691 label: gk773384 - class: variation id: WBVar00500046 label: gk276803 - class: variation id: WBVar01136680 label: gk345927 - class: variation id: WBVar01136715 label: gk355033 - class: variation id: WBVar01136733 label: gk892051 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01490289 label: gk954552 - class: variation id: WBVar01136687 label: gk571096 - class: variation id: WBVar01136679 label: gk394234 - class: variation id: WBVar01136697 label: gk463728 - class: variation id: WBVar00252937 label: tm4469 - class: variation id: WBVar00500034 label: gk276791 - class: variation id: WBVar01136723 label: gk410358 - class: variation id: WBVar01136710 label: gk354023 - class: variation id: WBVar01136681 label: gk643978 - class: variation id: WBVar01474070 label: tm6181 - class: variation id: WBVar01136664 label: gk325410 - class: variation id: WBVar01136735 label: gk681938 - class: variation id: WBVar01136745 label: gk322747 - class: variation id: WBVar00500041 label: gk276798 - class: variation id: WBVar01136658 label: gk571095 - class: variation id: WBVar01136726 label: gk495632 - class: variation id: WBVar01486751 label: gk951012 - class: variation id: WBVar00500050 label: gk276807 - class: variation id: WBVar00500033 label: gk276790 - class: variation id: WBVar01136714 label: gk905788 - class: variation id: WBVar01136663 label: gk787520 - class: variation id: WBVar01136750 label: gk316920 - class: variation id: WBVar01136740 label: gk831087 - class: variation id: WBVar00500037 label: gk276794 - class: variation id: WBVar01136708 label: gk445548 - class: variation id: WBVar01136720 label: gk541980 - class: variation id: WBVar00239179 label: pk37 - class: variation id: WBVar01136718 label: gk484709 - class: variation id: WBVar01136677 label: gk346821 - class: variation id: WBVar01136753 label: gk349680 - class: variation id: WBVar01136749 label: gk399932 - class: variation id: WBVar00500030 label: gk276787 - class: variation id: WBVar01136669 label: gk778838 - class: variation id: WBVar01136741 label: gk369621 - class: variation id: WBVar01136659 label: gk499674 - class: variation id: WBVar01136699 label: gk331891 - class: variation id: WBVar01136707 label: gk449376 - class: variation id: WBVar01136700 label: gk360397 - class: variation id: WBVar01136742 label: gk825539 - class: variation id: WBVar01136731 label: gk358066 - class: variation id: WBVar01136716 label: gk833119 - class: variation id: WBVar01136705 label: gk706691 - class: variation id: WBVar01136748 label: gk677096 - class: variation id: WBVar01136719 label: gk452581 - class: variation id: WBVar01136675 label: gk784358 - class: variation id: WBVar01136755 label: gk616917 - class: variation id: WBVar01136671 label: gk655520 - class: variation id: WBVar01136712 label: gk416985 - class: variation id: WBVar00500042 label: gk276799 - class: variation id: WBVar01136704 label: gk841941 - class: variation id: WBVar01136685 label: gk528940 - class: variation id: WBVar01136729 label: gk902332 - class: variation id: WBVar00500038 label: gk276795 - class: variation id: WBVar01136690 label: gk773383 - class: variation id: WBVar01136674 label: gk388854 - class: variation id: WBVar01136660 label: gk918726 - class: variation id: WBVar01136665 label: gk805886 - class: variation id: WBVar01136737 label: gk675513 - class: variation id: WBVar01136688 label: gk432948 - class: variation id: WBVar01136727 label: gk337290 - class: variation id: WBVar01136695 label: gk762944 - class: variation id: WBVar00500039 label: gk276796 - class: variation id: WBVar01136724 label: gk403693 - class: variation id: WBVar00500045 label: gk276802 - class: variation id: WBVar01136738 label: gk429888 - class: variation id: WBVar00500032 label: gk276789 - class: variation id: WBVar01136744 label: gk448750 - class: variation id: WBVar01136666 label: gk358065 - class: variation id: WBVar01136725 label: gk483206 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar01136754 label: gk865670 - class: variation id: WBVar01136713 label: gk640748 - class: variation id: WBVar01136673 label: gk427126 - class: variation id: WBVar00500026 label: gk276783 - class: variation id: WBVar01499561 label: gk963632 - class: variation id: WBVar00500031 label: gk276788 - class: variation id: WBVar01136734 label: gk341909 - class: variation id: WBVar01136702 label: gk578667 - class: variation id: WBVar01136706 label: gk467954 - class: variation id: WBVar01136711 label: gk416984 - class: variation id: WBVar01136703 label: gk801004 - class: variation id: WBVar01136686 label: gk494935 - class: variation id: WBVar00500028 label: gk276785 - class: variation id: WBVar01136736 label: gk500053 - class: variation id: WBVar01136696 label: gk569151 - class: variation id: WBVar01136739 label: gk317045 - class: variation id: WBVar01491994 label: gk956257 - class: variation id: WBVar01136694 label: gk527922 - class: variation id: WBVar01136752 label: gk586223 - class: variation id: WBVar01136668 label: gk779365 - class: variation id: WBVar01136746 label: gk390959 - class: variation id: WBVar00500036 label: gk276793 - class: variation id: WBVar01136692 label: gk391832 - class: variation id: WBVar01486752 label: gk951013 - class: variation id: WBVar01136676 label: gk682315 - class: variation id: WBVar00088900 label: mg58 - class: variation id: WBVar00500029 label: gk276786 - class: variation id: WBVar01136689 label: gk773382 - class: variation id: WBVar01136730 label: gk394749 - class: variation id: WBVar01136662 label: gk626323 - class: variation id: WBVar01136728 label: gk748464 - class: variation id: WBVar00500035 label: gk276792 - class: variation id: WBVar01136661 label: gk646457 - class: variation id: WBVar02144657 label: tm7507 - class: variation id: WBVar01136709 label: gk389971 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including determination of adult lifespan; gamete generation; and negative regulation of oocyte maturation. Located in nucleus. Expressed in body wall musculature; gonad; neurons; non-striated muscle; and somatic nervous system. Is an ortholog of human POU2F2 (POU class 2 homeobox 2) and POU2F3 (POU class 2 homeobox 3). label: ceh-18 legacy_description: ceh-18 encodes a POU-class homeodomain transcription factor; CEH-18 is required in hermaphrodites for specific aspects of gonadal sheath cell differentiation, such as normal cell shape and position, that are essential for negative regulation of oocyte meiotic maturation by the sheath cells; in this process, CEH-18 functions in parallel with the VAB-1/Ephrin receptor as part of a sperm-sensing checkpoint mechanism that prevents oocyte maturation, MAPK activation, and ovulation in the absence of sperm; CEH-18 is expressed in the sheath cell nuclei beginning at the L4 larval stage merged_into: ~ name: class: gene highlight: description_all: - ceh-18 encodes a POU-class homeodomain transcription factor; CEH-18 is required in hermaphrodites for - essential for negative regulation of oocyte meiotic maturation by the sheath cells; in this process, CEH-18 - mechanism that prevents oocyte maturation, MAPK activation, and ovulation in the absence of sperm; CEH-18 id: WBGene00000441 label: ceh-18 other_names: - ZC64.3 - CELE_ZC64.3 - CE25674 - ZC64.3b.2 - ZC64.3b - ZC64.3a - ZC64.3a.1 - CE54237 - ZC64.3b.1 taxonomy: c_elegans other_names: - ZC64.3 - CELE_ZC64.3 - CE25674 - ZC64.3b.2 - ZC64.3b - ZC64.3a - ZC64.3a.1 - CE54237 - ZC64.3b.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000441 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase domain. Is an ortholog of C. elegans mab-21. In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail mating organ morphogenesis." label: Bma-mab-21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mab-21 domain and Mab-21 protein nucleotidyltransferase" - Is an ortholog of C. elegans mab-21. - In C. elegans, mab-21 is involved in cell fate commitment; embryo development; and nematode male tail id: WBGene00224108 label: Bma-mab-21 other_names: - Bm3847 - Bm1_57360A - Bm1_57360 - TAG3847 - TAG8165 - BM36963 - Bm3847 - Bm3847.1 taxonomy: b_malayi other_names: - Bm3847 - Bm1_57360A - Bm1_57360 - TAG3847 - TAG8165 - BM36963 - Bm3847 - Bm3847.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00224108 - allele: - class: variation id: WBVar00420960 label: gk197717 - class: variation id: WBVar00897733 label: gk628300 - class: variation id: WBVar00897768 label: gk666569 - class: variation id: WBVar00897745 label: gk626038 - class: variation id: WBVar00897740 label: gk376139 - class: variation id: WBVar01498316 label: gk962726 - class: variation id: WBVar00897738 label: gk516077 - class: variation id: WBVar00897743 label: gk927647 - class: variation id: WBVar00420968 label: gk197725 - class: variation id: WBVar00897747 label: gk911230 - class: variation id: WBVar00897764 label: gk600638 - class: variation id: WBVar00897736 label: gk748936 - class: variation id: WBVar00897752 label: gk367212 - class: variation id: WBVar00265918 label: ttTi52930 - class: variation id: WBVar00897757 label: gk904515 - class: variation id: WBVar00897754 label: gk563038 - class: variation id: WBVar00420967 label: gk197724 - class: variation id: WBVar01499789 label: gk963907 - class: variation id: WBVar00420959 label: gk197716 - class: variation id: WBVar00897735 label: gk643330 - class: variation id: WBVar00420969 label: gk197726 - class: variation id: WBVar00897771 label: gk610990 - class: variation id: WBVar00420958 label: gk197715 - class: variation id: WBVar00897751 label: gk766683 - class: variation id: WBVar00420955 label: gk197712 - class: variation id: WBVar00897741 label: gk364378 - class: variation id: WBVar00897772 label: gk867386 - class: variation id: WBVar00897739 label: gk815410 - class: variation id: WBVar00420954 label: gk197711 - class: variation id: WBVar00092077 label: ok797 - class: variation id: WBVar00420963 label: gk197720 - class: variation id: WBVar00420953 label: gk197710 - class: variation id: WBVar00897761 label: gk703364 - class: variation id: WBVar00897737 label: gk829504 - class: variation id: WBVar00897763 label: gk665677 - class: variation id: WBVar02133571 label: h16955 - class: variation id: WBVar00420966 label: gk197723 - class: variation id: WBVar02152152 label: tm11851 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00420957 label: gk197714 - class: variation id: WBVar00897758 label: gk866838 - class: variation id: WBVar00420956 label: gk197713 - class: variation id: WBVar00897760 label: gk523303 - class: variation id: WBVar02133570 label: h8330 - class: variation id: WBVar00897762 label: gk347100 - class: variation id: WBVar00420962 label: gk197719 - class: variation id: WBVar00897753 label: gk771947 - class: variation id: WBVar00897773 label: gk391381 - class: variation id: WBVar00897766 label: gk881920 - class: variation id: WBVar00091280 label: nj37 - class: variation id: WBVar00897767 label: gk832866 - class: variation id: WBVar00420965 label: gk197722 - class: variation id: WBVar00897755 label: gk535623 - class: variation id: WBVar00897734 label: gk820607 - class: variation id: WBVar01499440 label: gk963481 - class: variation id: WBVar00420964 label: gk197721 - class: variation id: WBVar00897746 label: gk573904 - class: variation id: WBVar00897742 label: gk769940 - class: variation id: WBVar00897748 label: gk733038 - class: variation id: WBVar00897770 label: gk348486 - class: variation id: WBVar00420961 label: gk197718 - class: variation id: WBVar00897749 label: gk467650 - class: variation id: WBVar00897744 label: gk479994 - class: variation id: WBVar00897756 label: gk442962 - class: variation id: WBVar00897759 label: gk671875 - class: variation id: WBVar00897769 label: gk848384 - class: variation id: WBVar00897750 label: gk708867 - class: variation id: WBVar00897765 label: gk659902 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable adenylate cyclase activity; guanylate cyclase activity; and peptide receptor activity. Involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. Located in neuron projection terminus. Expressed in AFDL and AFDR. label: gcy-23 legacy_description: gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings. merged_into: ~ name: class: gene highlight: description_all: - gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily - of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream - thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 id: WBGene00001548 label: gcy-23 other_names: - T26C12.4 - CELE_T26C12.4 - T26C12.4.1 - CE41702 - T26C12.4 taxonomy: c_elegans other_names: - T26C12.4 - CELE_T26C12.4 - T26C12.4.1 - CE41702 - T26C12.4 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001548 - allele: - class: variation id: WBVar00435447 label: gk212204 - class: variation id: WBVar00941825 label: gk737913 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00941829 label: gk887790 - class: variation id: WBVar00941830 label: gk866152 - class: variation id: WBVar00435446 label: gk212203 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00941828 label: gk466214 - class: variation id: WBVar00941832 label: gk438907 - class: variation id: WBVar00435445 label: gk212202 - class: variation id: WBVar00941831 label: gk452281 - class: variation id: WBVar00941826 label: gk380718 - class: variation id: WBVar00435448 label: gk212205 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00941827 label: gk473732 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Involved in mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 18. Is an ortholog of human NDUFAF3 (NADH:ubiquinone oxidoreductase complex assembly factor 3). label: nuaf-3 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 18. id: WBGene00011123 label: nuaf-3 other_names: - R07H5.3 - CELE_R07H5.3 - R07H5.3c - R07H5.3a.1 - CE42589 - R07H5.3a - R07H5.3c.1 - CE35186 taxonomy: c_elegans other_names: - R07H5.3 - CELE_R07H5.3 - R07H5.3c - R07H5.3a.1 - CE42589 - R07H5.3a - R07H5.3c.1 - CE35186 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00011123 - allele: - class: variation id: WBVar02140850 label: h5889 - class: variation id: WBVar01220266 label: gk528541 - class: variation id: WBVar01220281 label: gk402712 - class: variation id: WBVar01220261 label: gk495058 - class: variation id: WBVar01220288 label: gk669790 - class: variation id: WBVar01499562 label: gk963633 - class: variation id: WBVar01220268 label: gk464431 - class: variation id: WBVar00528430 label: gk305187 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar00314171 label: otn17350 - class: variation id: WBVar01220277 label: gk418103 - class: variation id: WBVar01220283 label: gk501317 - class: variation id: WBVar02140852 label: h12295 - class: variation id: WBVar01220272 label: gk615282 - class: variation id: WBVar02140851 label: h16795 - class: variation id: WBVar01220269 label: gk735630 - class: variation id: WBVar01220270 label: gk901479 - class: variation id: WBVar00314172 label: otn17351 - class: variation id: WBVar01220275 label: gk540500 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar00528431 label: gk305188 - class: variation id: WBVar01220271 label: gk810028 - class: variation id: WBVar00260418 label: ttTi27099 - class: variation id: WBVar01220282 label: gk763565 - class: variation id: WBVar01220284 label: gk500865 - class: variation id: WBVar01220273 label: gk451638 - class: variation id: WBVar01220262 label: gk615921 - class: variation id: WBVar00528432 label: gk305189 - class: variation id: WBVar00528426 label: gk305183 - class: variation id: WBVar00528428 label: gk305185 - class: variation id: WBVar01220276 label: gk842721 - class: variation id: WBVar01220286 label: gk545850 - class: variation id: WBVar00528427 label: gk305184 - class: variation id: WBVar02148191 label: tm10431 - class: variation id: WBVar01498827 label: gk962525 - class: variation id: WBVar01220263 label: gk365846 - class: variation id: WBVar00528429 label: gk305186 - class: variation id: WBVar01220287 label: gk416104 - class: variation id: WBVar01499519 label: gk963581 - class: variation id: WBVar00314170 label: otn17349 - class: variation id: WBVar01499710 label: gk963810 - class: variation id: WBVar01220279 label: gk342643 - class: variation id: WBVar00528433 label: gk305190 - class: variation id: WBVar01220267 label: gk607404 - class: variation id: WBVar00314169 label: otn17348 - class: variation id: WBVar01220278 label: gk318931 - class: variation id: WBVar01220280 label: gk847479 - class: variation id: WBVar01220274 label: gk379159 - class: variation id: WBVar01220264 label: gk549541 - class: variation id: WBVar01220285 label: gk658258 - class: variation id: WBVar01220265 label: gk867089 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in transmembrane transport. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 18. Is an ortholog of human SLC25A21 (solute carrier family 25 member 21). label: slc-25A21 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in mitochondrial DNA depletion syndrome 18. id: WBGene00011226 label: slc-25A21 other_names: - R11.1 - CELE_R11.1 - R11.1 - CE31578 - R11.1.1 taxonomy: c_elegans other_names: - R11.1 - CELE_R11.1 - R11.1 - CE31578 - R11.1.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00011226 - allele: - class: variation id: WBVar00788820 label: gk703238 - class: variation id: WBVar00788793 label: gk515346 - class: variation id: WBVar00385093 label: gk161850 - class: variation id: WBVar00788781 label: gk900469 - class: variation id: WBVar00788809 label: gk629618 - class: variation id: WBVar00253555 label: ttTi1733 - class: variation id: WBVar00788789 label: gk904120 - class: variation id: WBVar00788797 label: gk601907 - class: variation id: WBVar00385100 label: gk161857 - class: variation id: WBVar00788778 label: gk766600 - class: variation id: WBVar01478718 label: gk942977 - class: variation id: WBVar00788838 label: gk575591 - class: variation id: WBVar00788818 label: gk581219 - class: variation id: WBVar00385084 label: gk161841 - class: variation id: WBVar00385086 label: gk161843 - class: variation id: WBVar00788817 label: gk671187 - class: variation id: WBVar00788821 label: gk622275 - class: variation id: WBVar00788800 label: gk565123 - class: variation id: WBVar00145287 label: ev774 - class: variation id: WBVar01498941 label: gk962684 - class: variation id: WBVar00385085 label: gk161842 - class: variation id: WBVar00788834 label: gk843309 - class: variation id: WBVar00385081 label: gk161838 - class: variation id: WBVar00788777 label: gk599169 - class: variation id: WBVar00788822 label: gk529693 - class: variation id: WBVar00788792 label: gk868827 - class: variation id: WBVar00385083 label: gk161840 - class: variation id: WBVar00788840 label: gk423213 - class: variation id: WBVar00145280 label: ev738 - class: variation id: WBVar00385097 label: gk161854 - class: variation id: WBVar00385099 label: gk161856 - class: variation id: WBVar00788784 label: gk617169 - class: variation id: WBVar00385102 label: gk161859 - class: variation id: WBVar00788787 label: gk353185 - class: variation id: WBVar01490014 label: gk954277 - class: variation id: WBVar00788801 label: gk571341 - class: variation id: WBVar00145288 label: ev775 - class: variation id: WBVar00788815 label: gk695346 - class: variation id: WBVar00788798 label: gk368024 - class: variation id: WBVar00788791 label: gk662190 - class: variation id: WBVar00385088 label: gk161845 - class: variation id: WBVar00788803 label: gk687082 - class: variation id: WBVar00788785 label: gk521652 - class: variation id: WBVar00788804 label: gk639745 - class: variation id: WBVar00788808 label: gk767092 - class: variation id: WBVar00788826 label: gk924785 - class: variation id: WBVar00788802 label: gk650299 - class: variation id: WBVar00145286 label: ev773 - class: variation id: WBVar00090930 label: nc7 - class: variation id: WBVar00788835 label: gk412659 - class: variation id: WBVar01488974 label: gk953237 - class: variation id: WBVar00385087 label: gk161844 - class: variation id: WBVar00788828 label: gk568263 - class: variation id: WBVar00788796 label: gk789580 - class: variation id: WBVar00788833 label: gk933012 - class: variation id: WBVar00788811 label: gk805678 - class: variation id: WBVar00788814 label: gk347743 - class: variation id: WBVar00788783 label: gk338383 - class: variation id: WBVar00788788 label: gk499875 - class: variation id: WBVar00788831 label: gk553814 - class: variation id: WBVar00788839 label: gk832113 - class: variation id: WBVar00788780 label: gk728483 - class: variation id: WBVar02145227 label: tm8064 - class: variation id: WBVar00385103 label: gk161860 - class: variation id: WBVar00276886 label: gk2864 - class: variation id: WBVar00788816 label: gk863846 - class: variation id: WBVar00788832 label: gk339984 - class: variation id: WBVar00385092 label: gk161849 - class: variation id: WBVar00788790 label: gk717815 - class: variation id: WBVar02146194 label: tm8211 - class: variation id: WBVar00385096 label: gk161853 - class: variation id: WBVar00788799 label: gk589302 - class: variation id: WBVar00788806 label: gk650300 - class: variation id: WBVar00788819 label: gk564569 - class: variation id: WBVar00385094 label: gk161851 - class: variation id: WBVar00249759 label: tm729 - class: variation id: WBVar00788827 label: gk667588 - class: variation id: WBVar00385104 label: gk161861 - class: variation id: WBVar00788779 label: gk766601 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00788782 label: gk808569 - class: variation id: WBVar00788824 label: gk375083 - class: variation id: WBVar00385090 label: gk161847 - class: variation id: WBVar00385098 label: gk161855 - class: variation id: WBVar00788829 label: gk844780 - class: variation id: WBVar00788841 label: gk412660 - class: variation id: WBVar00788776 label: gk599168 - class: variation id: WBVar00788786 label: gk516782 - class: variation id: WBVar00788836 label: gk715795 - class: variation id: WBVar00788813 label: gk620941 - class: variation id: WBVar00385082 label: gk161839 - class: variation id: WBVar00385089 label: gk161846 - class: variation id: WBVar00385091 label: gk161848 - class: variation id: WBVar00788795 label: gk650298 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00788807 label: gk434974 - class: variation id: WBVar00788830 label: gk558142 - class: variation id: WBVar00788825 label: gk604868 - class: variation id: WBVar00788837 label: gk397233 - class: variation id: WBVar00788794 label: gk654789 - class: variation id: WBVar00788775 label: gk759072 - class: variation id: WBVar00385095 label: gk161852 - class: variation id: WBVar00385101 label: gk161858 - class: variation id: WBVar00788812 label: gk792319 - class: variation id: WBVar00788823 label: gk488070 - class: variation id: WBVar00788810 label: gk769025 - class: variation id: WBVar00788805 label: gk555549 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables semaphorin receptor activity. Involved in several processes, including axonal fasciculation; nematode male tail tip morphogenesis; and regulation of axon guidance. Located in cell leading edge and cell surface. Expressed in several structures, including P3/4L; P9/10L; P9/10R; neuroblasts; and ray structural cell. label: plx-2 legacy_description: plx-2 encodes one of two C. elegans plexins, conserved transmembrane proteins that function as semaphorin receptors in both vertebrates and invertebrates; plx-2 activity is essential for proper male tail and epidermal morphogenesis and for normal axon guidance in a select group of neurons, including SDQL; genetic analyses indicate that plx-2 functions with mab-20/semaphorin-2a, efn-4/ephrin-4, and unc-129/TGF-beta to regulate male tail morphogenesis and with mab-20 and lad-2/L1CAM to mediate axon guidance; PLX-2 can bind MAB-20 and this interaction is enhanced in the presence of LAD-2; PLX-2::GFP reporters are expressed in a subset of neurons and epidermal cells, as well as a subset (1, 3, 5, and 7) of male sensory ray cell clusters. merged_into: ~ name: class: gene highlight: description_all: - guidance in a select group of neurons, including SDQL; genetic analyses indicate that plx-2 functions with mab - 20/semaphorin-2a, efn-4/ephrin-4, and unc-129/TGF-beta to regulate male tail morphogenesis and with mab - -20 and lad-2/L1CAM to mediate axon guidance; PLX-2 can bind MAB-20 and this interaction is enhanced id: WBGene00004048 label: plx-2 other_names: - K04B12.1 - CELE_K04B12.1 - cep-1 - CE53912 - K04B12.1 - K04B12.1.1 taxonomy: c_elegans other_names: - K04B12.1 - CELE_K04B12.1 - cep-1 - CE53912 - K04B12.1 - K04B12.1.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004048 - allele: - class: variation id: WBVar00415718 label: gk192475 - class: variation id: WBVar01481080 label: gk945339 - class: variation id: WBVar00881618 label: gk745842 - class: variation id: WBVar00415707 label: gk192464 - class: variation id: WBVar00881647 label: gk627572 - class: variation id: WBVar00881605 label: gk533398 - class: variation id: WBVar00252157 label: tm3485 - class: variation id: WBVar00881637 label: gk492674 - class: variation id: WBVar00881601 label: gk593346 - class: variation id: WBVar00415710 label: gk192467 - class: variation id: WBVar00881628 label: gk414880 - class: variation id: WBVar00881638 label: gk606358 - class: variation id: WBVar00256984 label: ttTi12705 - class: variation id: WBVar00415717 label: gk192474 - class: variation id: WBVar00881600 label: gk764828 - class: variation id: WBVar00881639 label: gk481485 - class: variation id: WBVar00881607 label: gk712718 - class: variation id: WBVar00881614 label: gk814840 - class: variation id: WBVar00881610 label: gk905027 - class: variation id: WBVar00415723 label: gk192480 - class: variation id: WBVar00881611 label: gk840594 - class: variation id: WBVar00881648 label: gk500269 - class: variation id: WBVar00415709 label: gk192466 - class: variation id: WBVar00415721 label: gk192478 - class: variation id: WBVar01499499 label: gk963558 - class: variation id: WBVar01481079 label: gk945338 - class: variation id: WBVar00881617 label: gk789037 - class: variation id: WBVar00881623 label: gk654392 - class: variation id: WBVar00881598 label: gk589956 - class: variation id: WBVar00881645 label: gk682199 - class: variation id: WBVar00415720 label: gk192477 - class: variation id: WBVar00881641 label: gk710482 - class: variation id: WBVar01499166 label: gk963025 - class: variation id: WBVar00881597 label: gk819401 - class: variation id: WBVar00881644 label: gk330980 - class: variation id: WBVar00093600 label: ok2454 - class: variation id: WBVar00881602 label: gk568364 - class: variation id: WBVar00881620 label: gk340543 - class: variation id: WBVar00881624 label: gk719703 - class: variation id: WBVar00415722 label: gk192479 - class: variation id: WBVar00881608 label: gk756779 - class: variation id: WBVar00881651 label: gk903114 - class: variation id: WBVar02133210 label: h5148 - class: variation id: WBVar00881642 label: gk563569 - class: variation id: WBVar00415712 label: gk192469 - class: variation id: WBVar00881650 label: gk419522 - class: variation id: WBVar00881649 label: gk516857 - class: variation id: WBVar00881619 label: gk465284 - class: variation id: WBVar00881627 label: gk865452 - class: variation id: WBVar00415711 label: gk192468 - class: variation id: WBVar00881622 label: gk412092 - class: variation id: WBVar00415715 label: gk192472 - class: variation id: WBVar00881613 label: gk311844 - class: variation id: WBVar00881635 label: gk682197 - class: variation id: WBVar00415719 label: gk192476 - class: variation id: WBVar00881615 label: gk397643 - class: variation id: WBVar00881646 label: gk837555 - class: variation id: WBVar00881625 label: gk510793 - class: variation id: WBVar00881629 label: gk525880 - class: variation id: WBVar00881636 label: gk682198 - class: variation id: WBVar01499498 label: gk963557 - class: variation id: WBVar00881606 label: gk891131 - class: variation id: WBVar00881632 label: gk583710 - class: variation id: WBVar00415713 label: gk192470 - class: variation id: WBVar00881612 label: gk849421 - class: variation id: WBVar00415708 label: gk192465 - class: variation id: WBVar00881621 label: gk520073 - class: variation id: WBVar00881633 label: gk504827 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00881626 label: gk890075 - class: variation id: WBVar00881634 label: gk444519 - class: variation id: WBVar00415716 label: gk192473 - class: variation id: WBVar00266399 label: ttTi55165 - class: variation id: WBVar00881616 label: gk753083 - class: variation id: WBVar00881603 label: gk610350 - class: variation id: WBVar00881609 label: gk627571 - class: variation id: WBVar00881631 label: gk769100 - class: variation id: WBVar00881630 label: gk913621 - class: variation id: WBVar00881640 label: gk722879 - class: variation id: WBVar00415714 label: gk192471 - class: variation id: WBVar00881599 label: gk759179 - class: variation id: WBVar00881604 label: gk807528 - class: variation id: WBVar00881643 label: gk557195 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable gap junction channel activity. Predicted to be involved in monoatomic ion transport and transmembrane transport. Located in gap junction. Expressed in g1; head neurons; and interneuron. label: inx-18 legacy_description: inx-18 encodes a predicted member of the innexin family. merged_into: ~ name: class: gene highlight: description_all: - inx-18 encodes a predicted member of the innexin family. id: WBGene00002140 label: inx-18 other_names: - C18H7.2 - opu-18 - CELE_C18H7.2 - CE31308 - C18H7.2b.1 - C18H7.2b - CE31309 - C18H7.2a.1 - C18H7.2b.2 - C18H7.2a taxonomy: c_elegans other_names: - C18H7.2 - opu-18 - CELE_C18H7.2 - CE31308 - C18H7.2b.1 - C18H7.2b - CE31309 - C18H7.2a.1 - C18H7.2b.2 - C18H7.2a page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00002140 - allele: - class: variation id: WBVar00796693 label: gk619042 - class: variation id: WBVar00796695 label: gk735759 - class: variation id: WBVar01500082 label: gk964281 - class: variation id: WBVar00796689 label: gk404327 - class: variation id: WBVar00796691 label: gk514917 - class: variation id: WBVar01499668 label: gk963761 - class: variation id: WBVar00796692 label: gk664914 - class: variation id: WBVar01498832 label: gk962532 - class: variation id: WBVar00796690 label: gk633864 - class: variation id: WBVar00796694 label: gk322237 - class: variation id: WBVar00387755 label: gk164512 - class: variation id: WBVar00387754 label: gk164511 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including elt-2; daf-18; and mex-3 based on tiling array; RNA-seq; and microarray studies. Is affected by six chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. label: K10F12.7 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including elt-2; daf-18; and mex-3 based on tiling array; RNA-seq; and microarray id: WBGene00019639 label: K10F12.7 other_names: - K10F12.7 - CELE_K10F12.7 - K10F12.7 - CE31039 - K10F12.7.1 taxonomy: c_elegans other_names: - K10F12.7 - CELE_K10F12.7 - K10F12.7 - CE31039 - K10F12.7.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00019639 - allele: - class: variation id: WBVar00729040 label: gk410828 - class: variation id: WBVar00729037 label: gk454761 - class: variation id: WBVar00365135 label: gk141892 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar01498761 label: gk964277 - class: variation id: WBVar00729039 label: gk547996 - class: variation id: WBVar00729036 label: gk915037 - class: variation id: WBVar00729035 label: gk562883 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00729034 label: gk672394 - class: variation id: WBVar00729041 label: gk644138 - class: variation id: WBVar00729038 label: gk420741 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in intestine based on microarray studies. Is affected by several genes including sir-2.1; nhr-49; and daf-18 based on RNA-seq and microarray studies. Is affected by paraquat and resveratrol based on RNA-seq and microarray studies. label: ZK546.19 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including sir-2.1; nhr-49; and daf-18 based on RNA-seq and microarray studies id: WBGene00195246 label: ZK546.19 other_names: - ZK546.19 - CELE_ZK546.19 - ZK546.19.1 - CE45346 - ZK546.19 taxonomy: c_elegans other_names: - ZK546.19 - CELE_ZK546.19 - ZK546.19.1 - CE45346 - ZK546.19 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00195246 - allele: - class: variation id: WBVar01071228 label: gk379736 - class: variation id: WBVar01071231 label: gk333974 - class: variation id: WBVar01071230 label: gk826583 - class: variation id: WBVar01499705 label: gk963805 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01500212 label: gk964458 - class: variation id: WBVar01500213 label: gk964459 - class: variation id: WBVar00478163 label: gk254920 - class: variation id: WBVar01499698 label: gk963796 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01071234 label: gk572250 - class: variation id: WBVar02137656 label: h18273 - class: variation id: WBVar01071233 label: gk802348 - class: variation id: WBVar01071229 label: gk511333 - class: variation id: WBVar01071227 label: gk575308 - class: variation id: WBVar01071232 label: gk797242 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in NSM; XXXL; and XXXR based on RNA-seq; tiling array; and single-cell RNA-seq studies. Is affected by several genes including daf-16; pgl-1; and daf-18 based on tiling array; RNA-seq; and microarray studies. label: F14H8.4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; pgl-1; and daf-18 based on tiling array; RNA-seq; and id: WBGene00008834 label: F14H8.4 other_names: - F14H8.4 - CELE_F14H8.4 - CE09395 - F14H8.4.1 - F14H8.4 taxonomy: c_elegans other_names: - F14H8.4 - CELE_F14H8.4 - CE09395 - F14H8.4.1 - F14H8.4 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00008834 - allele: - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01006361 label: gk639925 - class: variation id: WBVar01483932 label: gk948192 - class: variation id: WBVar01006369 label: gk316685 - class: variation id: WBVar01006365 label: gk602129 - class: variation id: WBVar01006364 label: gk629061 - class: variation id: WBVar01499496 label: gk963553 - class: variation id: WBVar01500066 label: gk964259 - class: variation id: WBVar01499740 label: gk963850 - class: variation id: WBVar01006366 label: gk628382 - class: variation id: WBVar01006370 label: gk722952 - class: variation id: WBVar01006363 label: gk747075 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01499528 label: gk963591 - class: variation id: WBVar01006368 label: gk353901 - class: variation id: WBVar01006367 label: gk760738 - class: variation id: WBVar01006362 label: gk790357 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is affected by several genes including daf-16; daf-2; and daf-18 based on microarray and RNA-seq studies. Is affected by six chemicals including multi-walled carbon nanotube; Psoralens; and allantoin based on RNA-seq and microarray studies. label: Y61A9LA.4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; daf-2; and daf-18 based on microarray and RNA-seq studies id: WBGene00022016 label: Y61A9LA.4 other_names: - Y61A9LA.4 - Y61A9LA.j - CELE_Y61A9LA.4 - Y61A9LA.4.1 - CE29131 - Y61A9LA.4 taxonomy: c_elegans other_names: - Y61A9LA.4 - Y61A9LA.j - CELE_Y61A9LA.4 - Y61A9LA.4.1 - CE29131 - Y61A9LA.4 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00022016 - allele: - class: variation id: WBVar01001287 label: gk607958 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01001289 label: gk657429 - class: variation id: WBVar00454806 label: gk231563 - class: variation id: WBVar00454809 label: gk231566 - class: variation id: WBVar00454812 label: gk231569 - class: variation id: WBVar01001296 label: gk734422 - class: variation id: WBVar01499496 label: gk963553 - class: variation id: WBVar01001277 label: gk471351 - class: variation id: WBVar00454810 label: gk231567 - class: variation id: WBVar01001274 label: gk399400 - class: variation id: WBVar01500066 label: gk964259 - class: variation id: WBVar02136126 label: h9864 - class: variation id: WBVar01499740 label: gk963850 - class: variation id: WBVar01001282 label: gk380759 - class: variation id: WBVar01001286 label: gk333352 - class: variation id: WBVar00454811 label: gk231568 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01001275 label: gk883452 - class: variation id: WBVar01001283 label: gk895192 - class: variation id: WBVar01001276 label: gk927794 - class: variation id: WBVar01001294 label: gk542624 - class: variation id: WBVar01001279 label: gk904581 - class: variation id: WBVar01001295 label: gk807114 - class: variation id: WBVar00454803 label: gk231560 - class: variation id: WBVar00454813 label: gk231570 - class: variation id: WBVar01499063 label: gk962867 - class: variation id: WBVar01001278 label: gk866212 - class: variation id: WBVar01499167 label: gk963027 - class: variation id: WBVar01001299 label: gk388234 - class: variation id: WBVar01001288 label: gk521175 - class: variation id: WBVar01001297 label: gk594562 - class: variation id: WBVar01499033 label: gk962826 - class: variation id: WBVar01001292 label: gk642822 - class: variation id: WBVar01001293 label: gk526011 - class: variation id: WBVar01001298 label: gk483948 - class: variation id: WBVar01001284 label: gk696383 - class: variation id: WBVar00454804 label: gk231561 - class: variation id: WBVar01001280 label: gk447872 - class: variation id: WBVar00454805 label: gk231562 - class: variation id: WBVar01001291 label: gk793128 - class: variation id: WBVar01483814 label: gk948074 - class: variation id: WBVar01483815 label: gk948075 - class: variation id: WBVar00454808 label: gk231565 - class: variation id: WBVar00454807 label: gk231564 - class: variation id: WBVar01499528 label: gk963591 - class: variation id: WBVar01483813 label: gk948073 - class: variation id: WBVar01001300 label: gk936833 - class: variation id: WBVar01001290 label: gk810383 - class: variation id: WBVar01001281 label: gk616815 - class: variation id: WBVar01001285 label: gk719816 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in germ line based on RNA-seq studies. Is affected by several genes including clk-1; daf-18; and unc-30 based on microarray and RNA-seq studies. Is affected by Colistin and dafa#1 based on microarray studies. label: fpn-1.3 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including clk-1; daf-18; and unc-30 based on microarray and RNA-seq studies id: WBGene00019969 label: fpn-1.3 other_names: - R08F11.6 - CELE_R08F11.6 - R08F11.6 taxonomy: c_elegans other_names: - R08F11.6 - CELE_R08F11.6 - R08F11.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00019969 - allele: - class: variation id: WBVar00865626 label: gk604966 - class: variation id: WBVar00865625 label: gk704771 - class: variation id: WBVar00865629 label: gk347799 - class: variation id: WBVar00865627 label: gk343555 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar00865624 label: gk325870 - class: variation id: WBVar01500139 label: gk964364 - class: variation id: WBVar00865628 label: gk324813 - class: variation id: WBVar01499701 label: gk963799 - class: variation id: WBVar01499239 label: gk963147 - class: variation id: WBVar01500138 label: gk964363 - class: variation id: WBVar00865623 label: gk355932 - class: variation id: WBVar00252916 label: tm4436 - class: variation id: WBVar00296380 label: tm4787 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable metal ion binding activity. Predicted to be involved in ribosome biogenesis. Predicted to be located in cytoplasm and nucleus. Expressed in head. Is an ortholog of human ZNF593 (zinc finger protein 593). label: znf-593 legacy_description: Y56A3A.18 encodes an ortholog of S. cerevisiae BUD20 that may suppress tumorous growth in the germ line by ensuring robust larval germline proliferation; like PRO-1, -2, and -3, Y56A3A.18 is thought to be required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germ line. merged_into: ~ name: class: gene highlight: description_all: - Y56A3A.18 encodes an ortholog of S. cerevisiae BUD20 that may suppress tumorous growth in the germ line - by ensuring robust larval germline proliferation; like PRO-1, -2, and -3, Y56A3A.18 is thought to be id: WBGene00013236 label: znf-593 other_names: - Y56A3A.18 - CELE_Y56A3A.18 - Y56A3A.18 - CE22586 - Y56A3A.18.1 taxonomy: c_elegans other_names: - Y56A3A.18 - CELE_Y56A3A.18 - Y56A3A.18 - CE22586 - Y56A3A.18.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00013236 - allele: - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar00344217 label: gk120974 - class: variation id: WBVar00667545 label: gk328324 - class: variation id: WBVar00344214 label: gk120971 - class: variation id: WBVar00667543 label: gk932456 - class: variation id: WBVar00667540 label: gk514796 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar00344216 label: gk120973 - class: variation id: WBVar00667552 label: gk710271 - class: variation id: WBVar00667550 label: gk728862 - class: variation id: WBVar00263771 label: ttTi40261 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00667549 label: gk721976 - class: variation id: WBVar00667553 label: gk638057 - class: variation id: WBVar00667551 label: gk627350 - class: variation id: WBVar00667548 label: gk603931 - class: variation id: WBVar00667544 label: gk564996 - class: variation id: WBVar00667547 label: gk881683 - class: variation id: WBVar00667554 label: gk918106 - class: variation id: WBVar00145741 label: gk334 - class: variation id: WBVar00344215 label: gk120972 - class: variation id: WBVar02151186 label: tm10825 - class: variation id: WBVar00667542 label: gk932455 - class: variation id: WBVar00667541 label: gk930772 - class: variation id: WBVar00667546 label: gk506898 - class: variation id: WBVar01490393 label: gk954656 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables histone H3K36 methyltransferase activity. Predicted to be involved in chromatin remodeling. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Expressed in body wall musculature; non-striated muscle; pharynx; and vulva. Is an ortholog of human SMYD1 (SET and MYND domain containing 1) and SMYD3 (SET and MYND domain containing 3). label: set-18 legacy_description: set-18 encodes, by alternative splicing, two isoforms of a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-18 is paralogous to SET-10, SET-14, and SET-30. merged_into: ~ name: class: gene highlight: description_all: - set-18 encodes, by alternative splicing, two isoforms of a divergent ortholog of human SMYD1 (OMIM:606846 - ), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-18 is paralogous to SET-10, SET-14, and SET-30. id: WBGene00044070 label: set-18 other_names: - T22A3.4 - tag-237 - CELE_T22A3.4 - CE13918 - T22A3.4a - T22A3.4a.1 - T22A3.4b.1 - CE32497 - T22A3.4b taxonomy: c_elegans other_names: - T22A3.4 - tag-237 - CELE_T22A3.4 - CE13918 - T22A3.4a - T22A3.4a.1 - T22A3.4b.1 - CE32497 - T22A3.4b page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00044070 - allele: - class: variation id: WBVar01137425 label: gk839059 - class: variation id: WBVar01137449 label: gk864658 - class: variation id: WBVar01137429 label: gk813688 - class: variation id: WBVar01137447 label: gk426194 - class: variation id: WBVar01137439 label: gk605975 - class: variation id: WBVar02151469 label: tm11120 - class: variation id: WBVar01137422 label: gk357510 - class: variation id: WBVar01137442 label: gk849108 - class: variation id: WBVar01137448 label: gk317833 - class: variation id: WBVar00145410 label: ga75 - class: variation id: WBVar01137424 label: gk806789 - class: variation id: WBVar00500324 label: gk277081 - class: variation id: WBVar01137437 label: gk414091 - class: variation id: WBVar01137430 label: gk597952 - class: variation id: WBVar01137428 label: gk516546 - class: variation id: WBVar01499636 label: gk963725 - class: variation id: WBVar01137434 label: gk569622 - class: variation id: WBVar00500320 label: gk277077 - class: variation id: WBVar00089924 label: n1051 - class: variation id: WBVar01137440 label: gk871671 - class: variation id: WBVar01137435 label: gk324526 - class: variation id: WBVar00143343 label: e620 - class: variation id: WBVar01137432 label: gk498331 - class: variation id: WBVar01137443 label: gk834611 - class: variation id: WBVar01137438 label: gk625538 - class: variation id: WBVar01137423 label: gk404909 - class: variation id: WBVar01137427 label: gk670146 - class: variation id: WBVar00500323 label: gk277080 - class: variation id: WBVar02139097 label: h10472 - class: variation id: WBVar01137445 label: gk619838 - class: variation id: WBVar01137433 label: gk636953 - class: variation id: WBVar02151551 label: tm11210 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar00500322 label: gk277079 - class: variation id: WBVar01137431 label: gk539781 - class: variation id: WBVar00500321 label: gk277078 - class: variation id: WBVar01137444 label: gk406606 - class: variation id: WBVar01137426 label: gk353463 - class: variation id: WBVar01137451 label: gk875785 - class: variation id: WBVar01499909 label: gk964060 - class: variation id: WBVar01137446 label: gk516222 - class: variation id: WBVar01137436 label: gk345809 - class: variation id: WBVar01137450 label: gk752791 - class: variation id: WBVar01137441 label: gk722455 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. Located in cytoplasm; nucleus; and plasma membrane. Expressed in body wall musculature; neurons; vulva; and vulval precursor cell. Is an ortholog of human RYK (receptor like tyrosine kinase). label: lin-18 legacy_description: lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate); in C. elegans, LIN-18 is required for establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell; LIN-18 may be a receptor for Wnt-like signaling molecules, and in vulval development appears to function independently of, but in parallel with, LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage; a lin-18 reporter gene is expressed in body wall muscle, neurons, and the developing vulva; in the vulva, expression is detected in P5.p, P6.p, and P7.p and all of their descendants during the L3 and L4 larval stages. merged_into: ~ name: class: gene highlight: description_all: - lin-18 encodes a predicted receptor tyrosine kinase that is a member of the Ryk/Derailed family of tyrosine - kinase-related receptors (OMIM:600524, mutations in humans are associated with cleft palate); in C. elegans, LIN-18 - establishing the polarity of the secondary vulval cell lineage produced by the P7.p vulval precursor cell; LIN-18 - LIN-17, a Frizzled-like Wnt receptor, also required for proper orientation of the P7.p lineage; a lin-18 id: WBGene00003007 label: lin-18 other_names: - C16B8.1 - CELE_C16B8.1 - C16B8.1.1 - C16B8.1 - CE44782 taxonomy: c_elegans other_names: - C16B8.1 - CELE_C16B8.1 - C16B8.1.1 - C16B8.1 - CE44782 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003007 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-31. In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. label: Cbr-mab-31 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-31. - In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor id: WBGene00035348 label: Cbr-mab-31 other_names: - CBG14981 - CBG_14981 - CBG14981 - CBP03618 - CBG14981.1 taxonomy: c_briggsae other_names: - CBG14981 - CBG_14981 - CBG14981 - CBP03618 - CBG14981.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00035348 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-31. In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. label: Cbn-mab-31 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-31. - In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor id: WBGene00194797 label: Cbn-mab-31 other_names: - CBN32715 - CBN32715 - CBN32715.1 - CN37332 taxonomy: c_brenneri other_names: - CBN32715 - CBN32715 - CBN32715.1 - CN37332 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00194797 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-31. In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. label: CJA37666 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-31. - In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor id: WBGene00213513 label: CJA37666 other_names: - CJA37666 - CJA37666b.1 - JA62005 - CJA37666b - CJA37666a - CJA37666a.1 - JA57969 taxonomy: c_japonica other_names: - CJA37666 - CJA37666b.1 - JA62005 - CJA37666b - CJA37666a - CJA37666a.1 - JA57969 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00213513 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-31. In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. label: Cjp-mab-31 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-31. - In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor id: WBGene00134536 label: Cjp-mab-31 other_names: - CJA15332 - CJA15332.1 - JA52202 - CJA15332 taxonomy: c_japonica other_names: - CJA15332 - CJA15332.1 - JA52202 - CJA15332 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00134536 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-31. In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. label: Cre-mab-31 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-31. - In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor id: WBGene00056413 label: Cre-mab-31 other_names: - CRE28387 - cr01.sctg6.wum.485 - RP22498 - CRE28387.1 - CRE28387 taxonomy: c_remanei other_names: - CRE28387 - cr01.sctg6.wum.485 - RP22498 - CRE28387.1 - CRE28387 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00056413 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-31. In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor beta receptor signaling pathway. label: Ppa-mab-31 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-31. - In C. elegans, mab-31 is involved in nematode male tail tip morphogenesis and transforming growth factor id: WBGene00108953 label: Ppa-mab-31 other_names: - PPA19399 - UMS-S10-38.0 - GENEPREDICTION_SNAP300000076213 - GENEPREDICTION_SNAP300000076214 - PPA19399.1 - PP64931 - PPA19399 taxonomy: p_pacificus other_names: - PPA19399 - UMS-S10-38.0 - GENEPREDICTION_SNAP300000076213 - GENEPREDICTION_SNAP300000076214 - PPA19399.1 - PP64931 - PPA19399 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00108953 - allele: - class: variation id: WBVar00662339 label: gk558689 - class: variation id: WBVar00662338 label: gk397172 - class: variation id: WBVar00662344 label: gk341375 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar02128236 label: h14114 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar00662345 label: gk422768 - class: variation id: WBVar01475944 label: gk940200 - class: variation id: WBVar00342540 label: gk119297 - class: variation id: WBVar00662347 label: gk920626 - class: variation id: WBVar00342541 label: gk119298 - class: variation id: WBVar01499786 label: gk963902 - class: variation id: WBVar00600930 label: tm5298 - class: variation id: WBVar00662337 label: gk748655 - class: variation id: WBVar00662342 label: gk661697 - class: variation id: WBVar01475945 label: gk940201 - class: variation id: WBVar00662343 label: gk584938 - class: variation id: WBVar00662341 label: gk409217 - class: variation id: WBVar00342542 label: gk119299 - class: variation id: WBVar00662340 label: gk576968 - class: variation id: WBVar00662346 label: gk362193 - class: variation id: WBVar00662348 label: gk537216 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein tyrosine/serine/threonine phosphatase activity. Predicted to be involved in dephosphorylation. Located in striated muscle myosin thick filament. Is an ortholog of human DUSP14 (dual specificity phosphatase 14); DUSP18 (dual specificity phosphatase 18); and DUSP21 (dual specificity phosphatase 21). label: C04F12.8 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - an ortholog of human DUSP14 (dual specificity phosphatase 14); DUSP18 (dual specificity phosphatase 18 id: WBGene00007302 label: C04F12.8 other_names: - C04F12.8 - CELE_C04F12.8 - C04F12.8.1 - C04F12.8 - CE47983 taxonomy: c_elegans other_names: - C04F12.8 - CELE_C04F12.8 - C04F12.8.1 - C04F12.8 - CE47983 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007302 - allele: - class: variation id: WBVar00954250 label: gk374848 - class: variation id: WBVar01499952 label: gk964111 - class: variation id: WBVar01499493 label: gk963547 - class: variation id: WBVar01482599 label: gk946859 - class: variation id: WBVar00954248 label: gk883971 - class: variation id: WBVar02151644 label: tm11305 - class: variation id: WBVar00954251 label: gk699450 - class: variation id: WBVar00954237 label: gk790267 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00439724 label: gk216481 - class: variation id: WBVar00954247 label: gk449754 - class: variation id: WBVar00954240 label: gk732403 - class: variation id: WBVar01499492 label: gk963546 - class: variation id: WBVar00954246 label: gk507456 - class: variation id: WBVar00954242 label: gk715390 - class: variation id: WBVar00954252 label: gk838302 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar01482598 label: gk946858 - class: variation id: WBVar00954239 label: gk818179 - class: variation id: WBVar00954249 label: gk780940 - class: variation id: WBVar00439729 label: gk216486 - class: variation id: WBVar00439730 label: gk216487 - class: variation id: WBVar00954244 label: gk558303 - class: variation id: WBVar00954241 label: gk922441 - class: variation id: WBVar00954238 label: gk327264 - class: variation id: WBVar00954253 label: gk768159 - class: variation id: WBVar00439726 label: gk216483 - class: variation id: WBVar00439727 label: gk216484 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00439725 label: gk216482 - class: variation id: WBVar00439728 label: gk216485 - class: variation id: WBVar01499951 label: gk964110 - class: variation id: WBVar00954245 label: gk768675 - class: variation id: WBVar00954243 label: gk676327 - class: variation id: WBVar02134972 label: h13982 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in head mesodermal cell based on RNA-seq studies. Is affected by several genes including rrf-3; eat-2; and daf-18 based on RNA-seq studies. Is affected by five chemicals including Rifampin; Psoralens; and Sirolimus based on RNA-seq studies. label: Y38H8A.8 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including rrf-3; eat-2; and daf-18 based on RNA-seq studies. id: WBGene00045062 label: Y38H8A.8 other_names: - Y38H8A.8 - CELE_Y38H8A.8 - Y38H8A.8 taxonomy: c_elegans other_names: - Y38H8A.8 - CELE_Y38H8A.8 - Y38H8A.8 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00045062 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Ppa-mab-5 legacy_description: Ppa-mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, Ppa-mab-5 is required for specification of posterior hypodermal cell fates including P8.p, a cell that fuses with the hypodermal syncytium hyp7 in wild-type animals; in Ppa-mab-5 mutant animals, P8.p forms ectopic vulva, a fate unknown from Cel-mab-5 mutants. merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation - Ppa-mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and - abdominal-A family of homeodomain proteins; during postembryonic development, Ppa-mab-5 is required for - -5 mutant animals, P8.p forms ectopic vulva, a fate unknown from Cel-mab-5 mutants. id: WBGene00195120 label: Ppa-mab-5 other_names: - PPA20022 - UMM-S66-6.15 - GENEPREDICTION_SNAP300000076838 - PPA20022 - PPA20022.1 - PP54939 taxonomy: p_pacificus other_names: - PPA20022 - UMM-S66-6.15 - GENEPREDICTION_SNAP300000076838 - PPA20022 - PPA20022.1 - PP54939 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00195120 - allele: - class: variation id: WBVar00680574 label: gk443493 - class: variation id: WBVar00680580 label: gk624103 - class: variation id: WBVar00680571 label: gk370428 - class: variation id: WBVar00680564 label: gk544262 - class: variation id: WBVar00255347 label: ttTi7382 - class: variation id: WBVar01499204 label: gk963095 - class: variation id: WBVar00680566 label: gk495190 - class: variation id: WBVar00249951 label: tm929 - class: variation id: WBVar00680582 label: gk867787 - class: variation id: WBVar00680572 label: gk421616 - class: variation id: WBVar00680586 label: gk627360 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00680581 label: gk851412 - class: variation id: WBVar00680577 label: gk828211 - class: variation id: WBVar00348717 label: gk125474 - class: variation id: WBVar00680589 label: gk603945 - class: variation id: WBVar00680590 label: gk548957 - class: variation id: WBVar00680563 label: gk380165 - class: variation id: WBVar00348714 label: gk125471 - class: variation id: WBVar00348716 label: gk125473 - class: variation id: WBVar00680576 label: gk728370 - class: variation id: WBVar00348715 label: gk125472 - class: variation id: WBVar01496332 label: gk960595 - class: variation id: WBVar00680588 label: gk548956 - class: variation id: WBVar00680579 label: gk897617 - class: variation id: WBVar00680565 label: gk820415 - class: variation id: WBVar00680587 label: gk398573 - class: variation id: WBVar00680575 label: gk564428 - class: variation id: WBVar00680570 label: gk780252 - class: variation id: WBVar00680569 label: gk605481 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar00680578 label: gk814585 - class: variation id: WBVar00680585 label: gk429584 - class: variation id: WBVar00680567 label: gk654138 - class: variation id: WBVar00680573 label: gk600413 - class: variation id: WBVar00348718 label: gk125475 - class: variation id: WBVar00348719 label: gk125476 - class: variation id: WBVar00348720 label: gk125477 - class: variation id: WBVar00680583 label: gk911573 - class: variation id: WBVar00680584 label: gk385351 - class: variation id: WBVar00680568 label: gk460791 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable 8-oxo-GDP phosphatase activity; 8-oxo-dGDP phosphatase activity; and magnesium ion binding activity. Located in sarcoplasmic reticulum. Expressed in spermatheca and vulval muscle. Is an ortholog of human NUDT18 (nudix hydrolase 18). label: ndx-1 legacy_description: The ndx-1 gene encodes a NUDIX hydrolase. merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human NUDT18 (nudix hydrolase 18). id: WBGene00003578 label: ndx-1 other_names: - T26E3.2 - CELE_T26E3.2 - T26E3.2.1 - T26E3.2 - CE14186 taxonomy: c_elegans other_names: - T26E3.2 - CELE_T26E3.2 - T26E3.2.1 - T26E3.2 - CE14186 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003578 - allele: - class: variation id: WBVar01498363 label: gk962848 - class: variation id: WBVar01499324 label: gk963319 - class: variation id: WBVar01499264 label: gk963219 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in AFD based on RNA-seq studies. Is affected by several genes including daf-16; sir-2.1; and daf-18 based on RNA-seq and microarray studies. Is affected by eleven chemicals including Psoralens; allantoin; and metformin based on RNA-seq and microarray studies. label: trpl-4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; sir-2.1; and daf-18 based on RNA-seq and microarray studies id: WBGene00021408 label: trpl-4 other_names: - Y38C1AB.6 - CELE_Y38C1AB.6 - Y38C1AB.6.1 - CE51291 - Y38C1AB.6 taxonomy: c_elegans other_names: - Y38C1AB.6 - CELE_Y38C1AB.6 - Y38C1AB.6.1 - CE51291 - Y38C1AB.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00021408 - allele: - class: variation id: WBVar00381691 label: gk158448 - class: variation id: WBVar00381695 label: gk158452 - class: variation id: WBVar00779083 label: gk932039 - class: variation id: WBVar00779047 label: gk400638 - class: variation id: WBVar00779016 label: gk929792 - class: variation id: WBVar00381704 label: gk158461 - class: variation id: WBVar00779060 label: gk821610 - class: variation id: WBVar00779032 label: gk592112 - class: variation id: WBVar00779085 label: gk566444 - class: variation id: WBVar00779029 label: gk450039 - class: variation id: WBVar00311979 label: otn15158 - class: variation id: WBVar00779061 label: gk358212 - class: variation id: WBVar00779084 label: gk392279 - class: variation id: WBVar00779067 label: gk377112 - class: variation id: WBVar00381709 label: gk158466 - class: variation id: WBVar00779076 label: gk673316 - class: variation id: WBVar00779070 label: gk405429 - class: variation id: WBVar00779018 label: gk750453 - class: variation id: WBVar00779056 label: gk637242 - class: variation id: WBVar00381705 label: gk158462 - class: variation id: WBVar00598500 label: gk309601 - class: variation id: WBVar00779049 label: gk648567 - class: variation id: WBVar00779062 label: gk736476 - class: variation id: WBVar01478303 label: gk942562 - class: variation id: WBVar00381689 label: gk158446 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00381688 label: gk158445 - class: variation id: WBVar00779048 label: gk741438 - class: variation id: WBVar00779051 label: gk385765 - class: variation id: WBVar02148132 label: tm10366 - class: variation id: WBVar00779042 label: gk648566 - class: variation id: WBVar00779052 label: gk746793 - class: variation id: WBVar00296699 label: tm4869 - class: variation id: WBVar00381703 label: gk158460 - class: variation id: WBVar00779021 label: gk679021 - class: variation id: WBVar00779039 label: gk604082 - class: variation id: WBVar00779014 label: gk718375 - class: variation id: WBVar00779072 label: gk562929 - class: variation id: WBVar00779064 label: gk674463 - class: variation id: WBVar00779035 label: gk847676 - class: variation id: WBVar00779092 label: gk915066 - class: variation id: WBVar00779015 label: gk511100 - class: variation id: WBVar02150383 label: tm12849 - class: variation id: WBVar00779055 label: gk713087 - class: variation id: WBVar00779043 label: gk658370 - class: variation id: WBVar00779077 label: gk754876 - class: variation id: WBVar00779023 label: gk358978 - class: variation id: WBVar01498829 label: gk962527 - class: variation id: WBVar00779075 label: gk673315 - class: variation id: WBVar00311984 label: otn15163 - class: variation id: WBVar00779017 label: gk867261 - class: variation id: WBVar00311982 label: otn15161 - class: variation id: WBVar00779078 label: gk548050 - class: variation id: WBVar00779090 label: gk838085 - class: variation id: WBVar00311981 label: otn15160 - class: variation id: WBVar00779066 label: gk397228 - class: variation id: WBVar00381710 label: gk158467 - class: variation id: WBVar00779088 label: gk713088 - class: variation id: WBVar02125562 label: tm6699 - class: variation id: WBVar00779040 label: gk558764 - class: variation id: WBVar00381701 label: gk158458 - class: variation id: WBVar00779081 label: gk667580 - class: variation id: WBVar00779053 label: gk887135 - class: variation id: WBVar00381707 label: gk158464 - class: variation id: WBVar00381711 label: gk158468 - class: variation id: WBVar00779093 label: gk368013 - class: variation id: WBVar00381702 label: gk158459 - class: variation id: WBVar00381700 label: gk158457 - class: variation id: WBVar00779038 label: gk932999 - class: variation id: WBVar00779058 label: gk791707 - class: variation id: WBVar01498941 label: gk962684 - class: variation id: WBVar00381713 label: gk158470 - class: variation id: WBVar00779022 label: gk601152 - class: variation id: WBVar00381693 label: gk158450 - class: variation id: WBVar00779045 label: gk372123 - class: variation id: WBVar00779026 label: gk466059 - class: variation id: WBVar00779089 label: gk843860 - class: variation id: WBVar00779065 label: gk716857 - class: variation id: WBVar00779068 label: gk398633 - class: variation id: WBVar00779013 label: gk566850 - class: variation id: WBVar00779037 label: gk387381 - class: variation id: WBVar00779082 label: gk804148 - class: variation id: WBVar00779091 label: gk838658 - class: variation id: WBVar00779019 label: gk831367 - class: variation id: WBVar00779050 label: gk419474 - class: variation id: WBVar00779086 label: gk777954 - class: variation id: WBVar00779030 label: gk640318 - class: variation id: WBVar00779054 label: gk767085 - class: variation id: WBVar00779071 label: gk606265 - class: variation id: WBVar00779028 label: gk822176 - class: variation id: WBVar00779073 label: gk854175 - class: variation id: WBVar00381706 label: gk158463 - class: variation id: WBVar00779033 label: gk821059 - class: variation id: WBVar00779095 label: gk830771 - class: variation id: WBVar00381692 label: gk158449 - class: variation id: WBVar00779031 label: gk514155 - class: variation id: WBVar00779059 label: gk750454 - class: variation id: WBVar00779074 label: gk595951 - class: variation id: WBVar00381698 label: gk158455 - class: variation id: WBVar00779024 label: gk466057 - class: variation id: WBVar00381697 label: gk158454 - class: variation id: WBVar00779025 label: gk466058 - class: variation id: WBVar00779044 label: gk656627 - class: variation id: WBVar01498828 label: gk962526 - class: variation id: WBVar00779087 label: gk374105 - class: variation id: WBVar00779094 label: gk619021 - class: variation id: WBVar00779034 label: gk870832 - class: variation id: WBVar02125216 label: tm6631 - class: variation id: WBVar00779027 label: gk524290 - class: variation id: WBVar00381696 label: gk158453 - class: variation id: WBVar00779069 label: gk924774 - class: variation id: WBVar00779046 label: gk806075 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00381708 label: gk158465 - class: variation id: WBVar00094513 label: ok3532 - class: variation id: WBVar00381699 label: gk158456 - class: variation id: WBVar00779057 label: gk502601 - class: variation id: WBVar00381690 label: gk158447 - class: variation id: WBVar00779079 label: gk897239 - class: variation id: WBVar01474307 label: cxTi10014 - class: variation id: WBVar00311980 label: otn15159 - class: variation id: WBVar00311983 label: otn15162 - class: variation id: WBVar00779020 label: gk733594 - class: variation id: WBVar00381694 label: gk158451 - class: variation id: WBVar00779080 label: gk819252 - class: variation id: WBVar00779041 label: gk869639 - class: variation id: WBVar00779063 label: gk614291 - class: variation id: WBVar00381712 label: gk158469 - class: variation id: WBVar00779036 label: gk602778 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Involved in endocytosis and molting cycle. Acts upstream of or within nematode male tail mating organ morphogenesis. Located in apical plasma membrane. Expressed in hypodermal cell; seam cell; and ventral cord blast cell. label: ptr-18 legacy_description: ptr-18 encodes a nematode-specific member of the sterol sensing domain(SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) andhuman PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-18is strongly required for normal molting from L3 to adult stage (a roleconserved in C. briggsae); PTR-18 is also required for male taildevelopment and vulval morphogenesis, and (partly) for endocytosis ofyolk by oocytes. merged_into: ~ name: class: gene highlight: description_all: - ptr-18 encodes a nematode-specific member of the sterol sensing domain(SSD) proteins, distantly paralogous - 18is strongly required for normal molting from L3 to adult stage (a roleconserved in C. briggsae); PTR-18 id: WBGene00004232 label: ptr-18 other_names: - Y38F1A.3 - CELE_Y38F1A.3 - Y38F1A.3 - Y38F1A.3.1 - CE43376 taxonomy: c_elegans other_names: - Y38F1A.3 - CELE_Y38F1A.3 - Y38F1A.3 - Y38F1A.3.1 - CE43376 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004232 - allele: - class: variation id: WBVar00451839 label: gk228596 - class: variation id: WBVar00992078 label: gk568999 - class: variation id: WBVar01499167 label: gk963027 - class: variation id: WBVar00451836 label: gk228593 - class: variation id: WBVar00992072 label: gk434221 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar00451835 label: gk228592 - class: variation id: WBVar00992071 label: gk507490 - class: variation id: WBVar00451832 label: gk228589 - class: variation id: WBVar00992080 label: gk641041 - class: variation id: WBVar00992077 label: gk638780 - class: variation id: WBVar00992075 label: gk917154 - class: variation id: WBVar01499496 label: gk963553 - class: variation id: WBVar00451837 label: gk228594 - class: variation id: WBVar01499528 label: gk963591 - class: variation id: WBVar00253939 label: ttTi3052 - class: variation id: WBVar00451838 label: gk228595 - class: variation id: WBVar00992082 label: gk420049 - class: variation id: WBVar00992079 label: gk818223 - class: variation id: WBVar01499537 label: gk963604 - class: variation id: WBVar00451833 label: gk228590 - class: variation id: WBVar02150870 label: tm4551 - class: variation id: WBVar00992076 label: gk551188 - class: variation id: WBVar00992081 label: gk723697 - class: variation id: WBVar00451840 label: gk228597 - class: variation id: WBVar00992073 label: gk356926 - class: variation id: WBVar00451834 label: gk228591 - class: variation id: WBVar00992074 label: gk768713 - class: variation id: WBVar01499740 label: gk963850 - class: variation id: WBVar01500066 label: gk964259 - class: variation id: WBVar00992070 label: gk568998 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA-binding transcription factor activity; sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Expressed in anal depressor muscle; intestinal muscle; and vulval muscle. label: nhr-18 legacy_description: The nhr-18 gene encodes a member of the superfamily of nuclear receptors, which is one of the most abundant class of transcriptional regulators; nuclear receptors have a well conserved DNA binding domain and a less conserved C-terminal ligand binding domain; the human homolog of nhr-18, CYP21, when mutated leads to congenital adrenal hyperplasia (OMIM:201910). merged_into: ~ name: class: gene highlight: description_all: - The nhr-18 gene encodes a member of the superfamily of nuclear receptors, which is one of the most abundant - DNA binding domain and a less conserved C-terminal ligand binding domain; the human homolog of nhr-18 id: WBGene00003617 label: nhr-18 other_names: - F44C8.3 - CELE_F44C8.3 - F44C8.3.1 - CE30796 - F44C8.3 taxonomy: c_elegans other_names: - F44C8.3 - CELE_F44C8.3 - F44C8.3.1 - CE30796 - F44C8.3 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003617 - allele: - class: variation id: WBVar00000393 label: b299 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Acts upstream of or within embryo development. label: mel-17 legacy_description: mel-17 was identified in screens for maternal-effect lethal mutations on chromosome II; mel-17 is defined by a single allele that results in somewhat leaky embryonic lethality that shows a moderate degree (18%) of zygotic rescue. merged_into: ~ name: class: gene highlight: description_all: - by a single allele that results in somewhat leaky embryonic lethality that shows a moderate degree (18% id: WBGene00003202 label: mel-17 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00003202 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: SNARE-complex protein Syntaxin-18, N-terminal and SNARE-complex protein Syntaxin-18 N-terminus. Is an ortholog of C. elegans syx-18." label: SRAE_1000003300 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: SNARE-complex protein Syntaxin-18, N-terminal" - and SNARE-complex protein Syntaxin-18 N-terminus. - Is an ortholog of C. elegans syx-18. id: WBGene00256626 label: SRAE_1000003300 other_names: - SRAE_1000003300 - SR03657 - SRAE_1000003300 - SRAE_1000003300.1 - SRP11525 taxonomy: s_ratti other_names: - SRAE_1000003300 - SR03657 - SRAE_1000003300 - SRAE_1000003300.1 - SRP11525 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00256626 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: CRE01694 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00077979 label: CRE01694 other_names: - CRE01694 - RP50350 - CRE01694 - CRE01694.1 taxonomy: c_remanei other_names: - CRE01694 - RP50350 - CRE01694 - CRE01694.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00077979 - allele: - class: variation id: WBVar00429592 label: gk206349 - class: variation id: WBVar00429594 label: gk206351 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00924068 label: gk861666 - class: variation id: WBVar00249971 label: tm949 - class: variation id: WBVar00924054 label: gk366042 - class: variation id: WBVar00924056 label: gk590557 - class: variation id: WBVar00924069 label: gk357356 - class: variation id: WBVar00924052 label: gk508001 - class: variation id: WBVar00924064 label: gk403950 - class: variation id: WBVar02147297 label: ns335 - class: variation id: WBVar02134226 label: h4301 - class: variation id: WBVar00429590 label: gk206347 - class: variation id: WBVar00924072 label: gk436519 - class: variation id: WBVar00924057 label: gk534734 - class: variation id: WBVar00924062 label: gk653264 - class: variation id: WBVar00924053 label: gk534221 - class: variation id: WBVar02151820 label: tm11488 - class: variation id: WBVar01499395 label: gk963416 - class: variation id: WBVar00924065 label: gk610382 - class: variation id: WBVar00429586 label: gk206343 - class: variation id: WBVar02148599 label: ns35 - class: variation id: WBVar00924050 label: gk564120 - class: variation id: WBVar00924061 label: gk404392 - class: variation id: WBVar00095041 label: oy44 - class: variation id: WBVar00429588 label: gk206345 - class: variation id: WBVar00924066 label: gk440539 - class: variation id: WBVar00258814 label: ttTi20839 - class: variation id: WBVar00924060 label: gk739567 - class: variation id: WBVar00924063 label: gk335558 - class: variation id: WBVar00924059 label: gk922386 - class: variation id: WBVar00924070 label: gk727385 - class: variation id: WBVar00924071 label: gk681663 - class: variation id: WBVar00924055 label: gk707170 - class: variation id: WBVar01499396 label: gk963417 - class: variation id: WBVar00429589 label: gk206346 - class: variation id: WBVar00924058 label: gk490531 - class: variation id: WBVar00924067 label: gk467691 - class: variation id: WBVar00429591 label: gk206348 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00429593 label: gk206350 - class: variation id: WBVar00924051 label: gk351143 - class: variation id: WBVar00429587 label: gk206344 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00924049 label: gk367237 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables guanylate cyclase activity. Involved in microvillus organization and response to temperature stimulus. Located in microvillus membrane and neuron projection terminus. Expressed in AFDL and AFDR. label: gcy-8 legacy_description: gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; GCY-8 is expressed exclusively in the AFD thermosensory neurons where it localizes to sensory endings; GCY-8 expression in the AFD neurons requires activity of the TAX-2/4 cyclic nucleotide gated channel and the CMK-1 Ca2+/calmodulin-dependent protein kinase I, while maintenance of GCY-8 expression requires the OTD/OTX homeodomain protein TTX-1. merged_into: ~ name: class: gene highlight: description_all: - gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily - of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream - thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 id: WBGene00001535 label: gcy-8 other_names: - C49H3.1 - CELE_C49H3.1 - C49H3.1 - CE42080 - C49H3.1.1 taxonomy: c_elegans other_names: - C49H3.1 - CELE_C49H3.1 - C49H3.1 - CE42080 - C49H3.1.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001535 - allele: - class: variation id: WBVar01029736 label: gk315187 - class: variation id: WBVar01029735 label: gk710644 - class: variation id: WBVar01029740 label: gk449821 - class: variation id: WBVar01029738 label: gk315188 - class: variation id: WBVar01029739 label: gk315189 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01500129 label: gk964351 - class: variation id: WBVar01029742 label: gk522454 - class: variation id: WBVar01499056 label: gk962860 - class: variation id: WBVar01029737 label: gk540299 - class: variation id: WBVar00464212 label: gk240969 - class: variation id: WBVar00252024 label: tm3304 - class: variation id: WBVar00464214 label: gk240971 - class: variation id: WBVar00464213 label: gk240970 - class: variation id: WBVar01029741 label: gk501173 - class: variation id: WBVar00464215 label: gk240972 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in receptor localization to non-motile cilium. Predicted to be part of BBSome. Expressed in amphid neurons and phasmid neurons. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 18. Is an ortholog of human BBIP1 (BBSome interacting protein 1). label: K07C11.10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 18. id: WBGene00019482 label: K07C11.10 other_names: - K07C11.10 - CELE_K07C11.10 - K07C11.10.1 - CE35335 - K07C11.10 taxonomy: c_elegans other_names: - K07C11.10 - CELE_K07C11.10 - K07C11.10.1 - CE35335 - K07C11.10 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00019482 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: CBN19022 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00157747 label: CBN19022 other_names: - CBN19022 - CBN19022 - CN08054 - CBN19022 - CBN19022.1 taxonomy: c_brenneri other_names: - CBN19022 - CBN19022 - CN08054 - CBN19022 - CBN19022.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00157747 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: CJA38562 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00214409 label: CJA38562 other_names: - CJA38562 - JA65266 - CJA38562 - CJA38562.1 taxonomy: c_japonica other_names: - CJA38562 - JA65266 - CJA38562 - CJA38562.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00214409 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Cjp-mab-20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00128109 label: Cjp-mab-20 other_names: - CJA08905 - CJA08905b.1 - CJA08905b - CJA08905a.1 - JA63885 - CJA08905a - JA62405 taxonomy: c_japonica other_names: - CJA08905 - CJA08905b.1 - CJA08905b - CJA08905a.1 - JA63885 - CJA08905a - JA62405 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00128109 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Cbr-mab-20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00040760 label: Cbr-mab-20 other_names: - CBG22137 - CBG_22137 - CBG22137.1 - CBP12026 - CBG22137 taxonomy: c_briggsae other_names: - CBG22137 - CBG_22137 - CBG22137.1 - CBP12026 - CBG22137 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00040760 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Cre-mab-20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00060535 label: Cre-mab-20 other_names: - CRE03930 - cr01.sctg18.wum.177 - CRE03930 - RP50336 - CRE03930.1 taxonomy: c_remanei other_names: - CRE03930 - cr01.sctg18.wum.177 - CRE03930 - RP50336 - CRE03930.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00060535 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Ppa-mab-20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00305163 label: Ppa-mab-20 other_names: - PPA47269 - PPA47269.1 - PPA47269 - PP75511 taxonomy: p_pacificus other_names: - PPA47269 - PPA47269.1 - PPA47269 - PP75511 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00305163 - allele: - class: variation id: WBVar00978300 label: gk787335 - class: variation id: WBVar00447378 label: gk224135 - class: variation id: WBVar01499167 label: gk963027 - class: variation id: WBVar00978327 label: gk330228 - class: variation id: WBVar00978296 label: gk629043 - class: variation id: WBVar01495937 label: gk960200 - class: variation id: WBVar00978308 label: gk700772 - class: variation id: WBVar00978318 label: gk355340 - class: variation id: WBVar00978309 label: gk662880 - class: variation id: WBVar00978324 label: gk447851 - class: variation id: WBVar00978307 label: gk832283 - class: variation id: WBVar00978336 label: gk391437 - class: variation id: WBVar00978297 label: gk329601 - class: variation id: WBVar01499528 label: gk963591 - class: variation id: WBVar00978306 label: gk359175 - class: variation id: WBVar00447383 label: gk224140 - class: variation id: WBVar00447375 label: gk224132 - class: variation id: WBVar00447382 label: gk224139 - class: variation id: WBVar00978301 label: gk593938 - class: variation id: WBVar00978302 label: gk802642 - class: variation id: WBVar00978328 label: gk763313 - class: variation id: WBVar00978310 label: gk848927 - class: variation id: WBVar00978322 label: gk788033 - class: variation id: WBVar00978315 label: gk744862 - class: variation id: WBVar00978321 label: gk746471 - class: variation id: WBVar00978323 label: gk514639 - class: variation id: WBVar00978304 label: gk738688 - class: variation id: WBVar00978293 label: gk508072 - class: variation id: WBVar00978303 label: gk382088 - class: variation id: WBVar00447380 label: gk224137 - class: variation id: WBVar00978299 label: gk505546 - class: variation id: WBVar00250483 label: tm1491 - class: variation id: WBVar00978298 label: gk919889 - class: variation id: WBVar00978311 label: gk699498 - class: variation id: WBVar00092792 label: ok1583 - class: variation id: WBVar00447381 label: gk224138 - class: variation id: WBVar00978333 label: gk808182 - class: variation id: WBVar02146174 label: tm8189 - class: variation id: WBVar00978338 label: gk715978 - class: variation id: WBVar00447379 label: gk224136 - class: variation id: WBVar00978337 label: gk821260 - class: variation id: WBVar00978330 label: gk611840 - class: variation id: WBVar00978294 label: gk476680 - class: variation id: WBVar00978313 label: gk820166 - class: variation id: WBVar00978334 label: gk354415 - class: variation id: WBVar00447374 label: gk224131 - class: variation id: WBVar00978326 label: gk404430 - class: variation id: WBVar00978335 label: gk413047 - class: variation id: WBVar00978332 label: gk705407 - class: variation id: WBVar00251856 label: tm3076 - class: variation id: WBVar00978320 label: gk698746 - class: variation id: WBVar00978305 label: gk411018 - class: variation id: WBVar00978314 label: gk626154 - class: variation id: WBVar01499775 label: gk963889 - class: variation id: WBVar00978331 label: gk625355 - class: variation id: WBVar00978295 label: gk508073 - class: variation id: WBVar00978316 label: gk527260 - class: variation id: WBVar00978325 label: gk703419 - class: variation id: WBVar00978319 label: gk818205 - class: variation id: WBVar02135531 label: h16525 - class: variation id: WBVar00447377 label: gk224134 - class: variation id: WBVar00447376 label: gk224133 - class: variation id: WBVar00978317 label: gk829588 - class: variation id: WBVar00978329 label: gk399389 - class: variation id: WBVar00978312 label: gk839596 - class: variation id: WBVar01499740 label: gk963850 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable neuropeptide binding activity and neuropeptide receptor activity. Involved in regulation of muscle contraction. Predicted to be located in neuron projection and plasma membrane. Expressed in body wall musculature; chemosensory neurons; and head neurons. Human ortholog(s) of this gene implicated in hypertension. Is an ortholog of human PRLHR (prolactin releasing hormone receptor). label: npr-5 legacy_description: Y58G8A.4 encodes, by alternative splicing, two isoforms of a receptor activated by FLP-18; in cell culture, Y58G8A.4 is bound and activated by FLP-18 peptides with nanomolar affinity, and acts primarily through Gq-alpha signalling in vitro (i.e., probably through EGL-30 in vivo); Y58G8A.4 is paralogous to NPR-1 (and many other C. elegans receptors), and homologous to the mammalian neuropeptide Y (NPY) receptor (OMIM:162641) required for regulating anxiety, food consumption, and pain sensation; other neuropeptides from Ascaris suum (AF3, AF4, and AF20), which share a C-terminal sequence with FLP-18, also activate Y58G8A.4; Y58G8A.4 has no obvious phenotype in mass RNAi assays. merged_into: ~ name: class: gene highlight: description_all: - Y58G8A.4 encodes, by alternative splicing, two isoforms of a receptor activated by FLP-18; in cell culture - ", Y58G8A.4 is bound and activated by FLP-18 peptides with nanomolar affinity, and acts primarily through" - other neuropeptides from Ascaris suum (AF3, AF4, and AF20), which share a C-terminal sequence with FLP-18 id: WBGene00021983 label: npr-5 other_names: - Y58G8A.4 - CELE_Y58G8A.4 - Y58G8A.4b.1 - Y58G8A.4a - Y58G8A.4b - CE33345 - Y58G8A.4a.1 - CE36962 taxonomy: c_elegans other_names: - Y58G8A.4 - CELE_Y58G8A.4 - Y58G8A.4b.1 - Y58G8A.4a - Y58G8A.4b - CE33345 - Y58G8A.4a.1 - CE36962 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00021983 - allele: - class: variation id: WBVar00144755 label: e2337 dead: !!perl/scalar:JSON::PP::Boolean 0 description: ~ label: eat-9 legacy_description: eat-9 is required for a normal speed and rhythm of pharyngeal pumping, and thus for normally efficient eating; since it phenotypically resembles eat-2 and eat-18, it (like them) may be required for pharyngeal excitation by the motor neuron MC; eat-9 is uncloned. merged_into: ~ name: class: gene highlight: description_all: - pharyngeal pumping, and thus for normally efficient eating; since it phenotypically resembles eat-2 and eat-18 id: WBGene00001140 label: eat-9 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00001140 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Ovo-mab-20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00237947 label: Ovo-mab-20 other_names: - OVOC1138 - OVOC1138.1 - OVOC1138 - OVP07580 taxonomy: o_volvulus other_names: - OVOC1138 - OVOC1138.1 - OVOC1138 - OVP07580 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00237947 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Cbn-mab-20.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00190718 label: Cbn-mab-20.1 other_names: - CBN28753 - CBN28753 - CBN28753.1 - CN36600 taxonomy: c_brenneri other_names: - CBN28753 - CBN28753 - CBN28753.1 - CN36600 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00190718 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: SRAE_2000034900 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00260542 label: SRAE_2000034900 other_names: - SRAE_2000034900 - SRAE_2000034900 - SRP06614 - SRAE_2000034900.1 taxonomy: s_ratti other_names: - SRAE_2000034900 - SRAE_2000034900 - SRP06614 - SRAE_2000034900.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00260542 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Bma-mab-20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00227321 label: Bma-mab-20 other_names: - Bm7060 - Bm1_48235 - TAG7060 - Bm-mab-20 - Bm7060.1 - BM42010 - Bm7060 taxonomy: b_malayi other_names: - Bm7060 - Bm1_48235 - TAG7060 - Bm-mab-20 - Bm7060.1 - BM42010 - Bm7060 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00227321 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable semaphorin receptor binding activity. Is an ortholog of C. elegans mab-20. In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; axonal fasciculation; and regulation of locomotion. label: Cbn-mab-20.2 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-20. - In C. elegans, mab-20 is involved in several processes, including anatomical structure morphogenesis; id: WBGene00193427 label: Cbn-mab-20.2 other_names: - CBN31462 - CN32802 - CBN31462.1 - CBN31462 taxonomy: c_brenneri other_names: - CBN31462 - CN32802 - CBN31462.1 - CBN31462 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00193427 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Orthologous to human MAB21L4 (mab-21 like 4); INTERACTS WITH acetamide; bisphenol A; Cuprizon. label: Mab21l4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Orthologous to human MAB21L4 (mab-21 like 4); INTERACTS WITH acetamide; bisphenol A; Cuprizon. id: RGD:1563692 label: Mab21l4 other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:1563692 - allele: - class: variation id: WBVar00906725 label: gk864918 - class: variation id: WBVar01499790 label: gk963908 - class: variation id: WBVar00906724 label: gk839497 - class: variation id: WBVar00906721 label: gk839496 - class: variation id: WBVar00265634 label: ttTi50574 - class: variation id: WBVar00423986 label: gk200743 - class: variation id: WBVar00906727 label: gk720582 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00906722 label: gk812995 - class: variation id: WBVar00906723 label: gk678532 - class: variation id: WBVar00906720 label: gk561285 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00423984 label: gk200741 - class: variation id: WBVar00423985 label: gk200742 - class: variation id: WBVar01499242 label: gk963150 - class: variation id: WBVar00906726 label: gk634767 - class: variation id: WBVar00094107 label: ok3021 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in cilium assembly. Predicted to be located in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital syndrome IV. Is an ortholog of human TCTN1 (tectonic family member 1) and TCTN3 (tectonic family member 3). label: tctn-1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in Joubert syndrome 13; Joubert syndrome 18; and orofaciodigital id: WBGene00017120 label: tctn-1 other_names: - E04A4.6 - CELE_E04A4.6 - E04A4.6.1 - CE46218 - E04A4.6 taxonomy: c_elegans other_names: - E04A4.6 - CELE_E04A4.6 - E04A4.6.1 - CE46218 - E04A4.6 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00017120 - allele: - class: variation id: WBVar00949694 label: gk435510 - class: variation id: WBVar00949777 label: gk611080 - class: variation id: WBVar01495303 label: gk959566 - class: variation id: WBVar00438256 label: gk215013 - class: variation id: WBVar00949784 label: gk601433 - class: variation id: WBVar00949750 label: gk803730 - class: variation id: WBVar00949755 label: gk625338 - class: variation id: WBVar00949713 label: gk582490 - class: variation id: WBVar00949801 label: gk530281 - class: variation id: WBVar00949739 label: gk788572 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00949751 label: gk719151 - class: variation id: WBVar00438229 label: gk214986 - class: variation id: WBVar01499493 label: gk963547 - class: variation id: WBVar00949782 label: gk507051 - class: variation id: WBVar00949763 label: gk668368 - class: variation id: WBVar00949762 label: gk508039 - class: variation id: WBVar00949711 label: gk353303 - class: variation id: WBVar00949701 label: gk838298 - class: variation id: WBVar00949787 label: gk932658 - class: variation id: WBVar01494763 label: gk959026 - class: variation id: WBVar00949761 label: gk898330 - class: variation id: WBVar00949704 label: gk807609 - class: variation id: WBVar01498173 label: gk962436 - class: variation id: WBVar01498982 label: gk962743 - class: variation id: WBVar00949698 label: gk387216 - class: variation id: WBVar00438226 label: gk214983 - class: variation id: WBVar00438248 label: gk215005 - class: variation id: WBVar00949772 label: gk844258 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar00949745 label: gk586968 - class: variation id: WBVar00949771 label: gk492203 - class: variation id: WBVar00949774 label: gk790874 - class: variation id: WBVar00949738 label: gk536393 - class: variation id: WBVar00949754 label: gk424831 - class: variation id: WBVar00438249 label: gk215006 - class: variation id: WBVar00949758 label: gk359787 - class: variation id: WBVar00949796 label: gk490213 - class: variation id: WBVar00949690 label: gk672582 - class: variation id: WBVar00949740 label: gk593415 - class: variation id: WBVar00949742 label: gk591741 - class: variation id: WBVar00949773 label: gk320430 - class: variation id: WBVar00949780 label: gk756191 - class: variation id: WBVar00949709 label: gk746415 - class: variation id: WBVar00949725 label: gk614422 - class: variation id: WBVar00949716 label: gk554249 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00949783 label: gk523340 - class: variation id: WBVar02134857 label: h16513 - class: variation id: WBVar00949726 label: gk362377 - class: variation id: WBVar00949695 label: gk331398 - class: variation id: WBVar00438259 label: gk215016 - class: variation id: WBVar00438253 label: gk215010 - class: variation id: WBVar00438238 label: gk214995 - class: variation id: WBVar00949789 label: gk523341 - class: variation id: WBVar00949792 label: gk652693 - class: variation id: WBVar00949732 label: gk903694 - class: variation id: WBVar00949741 label: gk750729 - class: variation id: WBVar00949693 label: gk570544 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00949735 label: gk351184 - class: variation id: WBVar00949747 label: gk777159 - class: variation id: WBVar00438233 label: gk214990 - class: variation id: WBVar00949743 label: gk341700 - class: variation id: WBVar00438254 label: gk215011 - class: variation id: WBVar02151191 label: tm10830 - class: variation id: WBVar00949746 label: gk761188 - class: variation id: WBVar00949798 label: gk852542 - class: variation id: WBVar00949720 label: gk818721 - class: variation id: WBVar00949696 label: gk483528 - class: variation id: WBVar01499492 label: gk963546 - class: variation id: WBVar00949688 label: gk333330 - class: variation id: WBVar00949723 label: gk857051 - class: variation id: WBVar00438231 label: gk214988 - class: variation id: WBVar00949691 label: gk795498 - class: variation id: WBVar00438252 label: gk215009 - class: variation id: WBVar00949776 label: gk889445 - class: variation id: WBVar00949707 label: gk417263 - class: variation id: WBVar00949769 label: gk340614 - class: variation id: WBVar00438232 label: gk214989 - class: variation id: WBVar00438243 label: gk215000 - class: variation id: WBVar00438237 label: gk214994 - class: variation id: WBVar00949689 label: gk520519 - class: variation id: WBVar00949733 label: gk557240 - class: variation id: WBVar00438251 label: gk215008 - class: variation id: WBVar00949702 label: gk765418 - class: variation id: WBVar00438245 label: gk215002 - class: variation id: WBVar00438224 label: gk214981 - class: variation id: WBVar00949790 label: gk778714 - class: variation id: WBVar00949775 label: gk389465 - class: variation id: WBVar00949703 label: gk621976 - class: variation id: WBVar00949781 label: gk835154 - class: variation id: WBVar00949756 label: gk626112 - class: variation id: WBVar01482491 label: gk946751 - class: variation id: WBVar00275922 label: ok5368 - class: variation id: WBVar00949730 label: gk796644 - class: variation id: WBVar00949705 label: gk361928 - class: variation id: WBVar00949700 label: gk721568 - class: variation id: WBVar01482494 label: gk946754 - class: variation id: WBVar01482489 label: gk946749 - class: variation id: WBVar00949752 label: gk431795 - class: variation id: WBVar00949722 label: gk636306 - class: variation id: WBVar00949770 label: gk773312 - class: variation id: WBVar00438241 label: gk214998 - class: variation id: WBVar00142338 label: cxTi10011 - class: variation id: WBVar00949721 label: gk862764 - class: variation id: WBVar00949778 label: gk415695 - class: variation id: WBVar00949687 label: gk422828 - class: variation id: WBVar00949795 label: gk777591 - class: variation id: WBVar00598789 label: gk310044 - class: variation id: WBVar01482492 label: gk946752 - class: variation id: WBVar00949719 label: gk812553 - class: variation id: WBVar00949686 label: gk666628 - class: variation id: WBVar00949724 label: gk362376 - class: variation id: WBVar00438230 label: gk214987 - class: variation id: WBVar00949748 label: gk413391 - class: variation id: WBVar00949697 label: gk526407 - class: variation id: WBVar00949768 label: gk894144 - class: variation id: WBVar00949749 label: gk392407 - class: variation id: WBVar00438247 label: gk215004 - class: variation id: WBVar00438242 label: gk214999 - class: variation id: WBVar01482490 label: gk946750 - class: variation id: WBVar00949706 label: gk573421 - class: variation id: WBVar00949753 label: gk937434 - class: variation id: WBVar01492959 label: gk957222 - class: variation id: WBVar00438246 label: gk215003 - class: variation id: WBVar00949699 label: gk701915 - class: variation id: WBVar01482495 label: gk946755 - class: variation id: WBVar00949788 label: gk754973 - class: variation id: WBVar00438255 label: gk215012 - class: variation id: WBVar00949718 label: gk564682 - class: variation id: WBVar00438239 label: gk214996 - class: variation id: WBVar00949728 label: gk432419 - class: variation id: WBVar00949793 label: gk919853 - class: variation id: WBVar00949734 label: gk569453 - class: variation id: WBVar00438257 label: gk215014 - class: variation id: WBVar00949708 label: gk481549 - class: variation id: WBVar00949760 label: gk360270 - class: variation id: WBVar00949766 label: gk601432 - class: variation id: WBVar00949757 label: gk601431 - class: variation id: WBVar00438250 label: gk215007 - class: variation id: WBVar00438228 label: gk214985 - class: variation id: WBVar00949717 label: gk552173 - class: variation id: WBVar00949692 label: gk835786 - class: variation id: WBVar00949715 label: gk935628 - class: variation id: WBVar00949759 label: gk864535 - class: variation id: WBVar00949712 label: gk651918 - class: variation id: WBVar00949736 label: gk903695 - class: variation id: WBVar00438225 label: gk214982 - class: variation id: WBVar00438235 label: gk214992 - class: variation id: WBVar00949729 label: gk633437 - class: variation id: WBVar00438240 label: gk214997 - class: variation id: WBVar00438227 label: gk214984 - class: variation id: WBVar00949744 label: gk752112 - class: variation id: WBVar00438236 label: gk214993 - class: variation id: WBVar00949779 label: gk409477 - class: variation id: WBVar00092184 label: ok912 - class: variation id: WBVar00949737 label: gk532855 - class: variation id: WBVar00438258 label: gk215015 - class: variation id: WBVar00949714 label: gk453833 - class: variation id: WBVar00949785 label: gk444175 - class: variation id: WBVar00949794 label: gk565749 - class: variation id: WBVar00949797 label: gk544572 - class: variation id: WBVar00949685 label: gk880273 - class: variation id: WBVar01482493 label: gk946753 - class: variation id: WBVar00949767 label: gk919236 - class: variation id: WBVar00949791 label: gk772010 - class: variation id: WBVar00438234 label: gk214991 - class: variation id: WBVar00949731 label: gk768152 - class: variation id: WBVar02151065 label: tm10692 - class: variation id: WBVar01497789 label: gk962052 - class: variation id: WBVar00949800 label: gk871545 - class: variation id: WBVar00949710 label: gk536950 - class: variation id: WBVar00438244 label: gk215001 - class: variation id: WBVar00949765 label: gk751466 - class: variation id: WBVar00949799 label: gk411719 - class: variation id: WBVar00949727 label: gk861696 - class: variation id: WBVar00949764 label: gk869060 - class: variation id: WBVar02151818 label: tm11486 - class: variation id: WBVar00949786 label: gk771078 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase binding activity. Predicted to be involved in protein localization. Predicted to be located in cytosol and membrane. Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. Is an ortholog of human WDFY3 (WD repeat and FYVE domain containing 3). label: wdfy-3 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in primary autosomal dominant microcephaly 18. id: WBGene00007752 label: wdfy-3 other_names: - C26H9A.2 - CELE_C26H9A.2 - C26H9A.2d - C26H9A.2d.1 - CE46974 - CE42572 - C26H9A.2a.1 - C26H9A.2b.1 - CE47015 - C26H9A.2b - C26H9A.2c.1 - CE46844 - C26H9A.2a - C26H9A.2c taxonomy: c_elegans other_names: - C26H9A.2 - CELE_C26H9A.2 - C26H9A.2d - C26H9A.2d.1 - CE46974 - CE42572 - C26H9A.2a.1 - C26H9A.2b.1 - CE47015 - C26H9A.2b - C26H9A.2c.1 - CE46844 - C26H9A.2a - C26H9A.2c page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007752 - allele: - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00780225 label: gk375603 - class: variation id: WBVar00780226 label: gk465608 - class: variation id: WBVar01498828 label: gk962526 - class: variation id: WBVar01498829 label: gk962527 - class: variation id: WBVar00780224 label: gk474596 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar01498941 label: gk962684 - class: variation id: WBVar00382094 label: gk158851 - class: variation id: WBVar02148345 label: tm10607 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in M cell based on single-cell RNA-seq studies. Is affected by several genes including eat-2; sir-2.1; and daf-18 based on microarray and RNA-seq studies. Is affected by five chemicals including D-glucose; Psoralens; and allantoin based on RNA-seq and microarray studies. label: F29C12.6 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including eat-2; sir-2.1; and daf-18 based on microarray and RNA-seq studies id: WBGene00009248 label: F29C12.6 other_names: - F29C12.6 - CELE_F29C12.6 - CE19824 - F29C12.6 - F29C12.6.1 taxonomy: c_elegans other_names: - F29C12.6 - CELE_F29C12.6 - CE19824 - F29C12.6 - F29C12.6.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00009248 - allele: - class: variation id: WBVar00407313 label: gk184070 - class: variation id: WBVar01492349 label: gk956612 - class: variation id: WBVar00856411 label: gk596002 - class: variation id: WBVar01499194 label: gk963083 - class: variation id: WBVar00856421 label: gk479380 - class: variation id: WBVar00856419 label: gk688509 - class: variation id: WBVar00856414 label: gk417178 - class: variation id: WBVar01500260 label: gk964518 - class: variation id: WBVar00856416 label: gk604951 - class: variation id: WBVar00856422 label: gk680958 - class: variation id: WBVar01480318 label: gk944577 - class: variation id: WBVar00407316 label: gk184073 - class: variation id: WBVar00856410 label: gk770986 - class: variation id: WBVar00856413 label: gk484365 - class: variation id: WBVar00856423 label: gk640429 - class: variation id: WBVar00407314 label: gk184071 - class: variation id: WBVar00407315 label: gk184072 - class: variation id: WBVar00407311 label: gk184068 - class: variation id: WBVar00856409 label: gk929198 - class: variation id: WBVar00856425 label: gk936704 - class: variation id: WBVar00856418 label: gk349029 - class: variation id: WBVar00856424 label: gk741524 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar00856420 label: gk906166 - class: variation id: WBVar00407310 label: gk184067 - class: variation id: WBVar00856412 label: gk889005 - class: variation id: WBVar00856415 label: gk575006 - class: variation id: WBVar00856417 label: gk809107 - class: variation id: WBVar00407312 label: gk184069 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of U4/U6 x U5 tri-snRNP complex. Human ortholog(s) of this gene implicated in retinitis pigmentosa 18. Is an ortholog of human PRPF3 (pre-mRNA processing factor 3). label: prp-3 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in retinitis pigmentosa 18. id: WBGene00010844 label: prp-3 other_names: - M03C11.7 - CELE_M03C11.7 - CE03498 - M03C11.7.1 - M03C11.7 taxonomy: c_elegans other_names: - M03C11.7 - CELE_M03C11.7 - CE03498 - M03C11.7.1 - M03C11.7 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00010844 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y41C4A.18. label: CBG13229 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y41C4A.18. id: WBGene00034020 label: CBG13229 other_names: - CBG13229 - CBG_13229 - CBP09315 - CBG13229.1 - CBG13229 taxonomy: c_briggsae other_names: - CBG13229 - CBG_13229 - CBP09315 - CBG13229.1 - CBG13229 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00034020 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.18. label: CBG18669 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.18. id: WBGene00038048 label: CBG18669 other_names: - CBG18669 - CBG_18669 - CBP26161 - CBG18669 - CBG18669.1 taxonomy: c_briggsae other_names: - CBG18669 - CBG_18669 - CBP26161 - CBG18669 - CBG18669.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00038048 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans cpg-18. label: CBG19873 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans cpg-18. id: WBGene00039014 label: CBG19873 other_names: - CBG19873 - CBG_19873 - CBG19873 - CBG19873.1 - CBP04649 taxonomy: c_briggsae other_names: - CBG19873 - CBG_19873 - CBG19873 - CBG19873.1 - CBP04649 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00039014 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nlp-18. label: Cre-nlp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nlp-18. id: WBGene00053491 label: Cre-nlp-18 other_names: - CRE01790 - cr01.sctg2.wum.275 - CRE01790.1 - RP23721 - CRE01790 taxonomy: c_remanei other_names: - CRE01790 - cr01.sctg2.wum.275 - CRE01790.1 - RP23721 - CRE01790 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00053491 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans pqn-18. label: Cre-pqn-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans pqn-18. id: WBGene00051183 label: Cre-pqn-18 other_names: - CRE24099 - cr01.sctg0.wum.198 - RP27259 - CRE24099 - CRE24099.1 taxonomy: c_remanei other_names: - CRE24099 - cr01.sctg0.wum.198 - RP27259 - CRE24099 - CRE24099.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00051183 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans tag-18. label: CRE00371 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tag-18. id: WBGene00051927 label: CRE00371 other_names: - CRE00371 - Cre-tag-18 - cr01.sctg0.wum.913 - RP06916 - CRE00371.1 - CRE00371 taxonomy: c_remanei other_names: - CRE00371 - Cre-tag-18 - cr01.sctg0.wum.913 - RP06916 - CRE00371.1 - CRE00371 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00051927 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y41C4A.18. label: CRE01030 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y41C4A.18. id: WBGene00063074 label: CRE01030 other_names: - CRE01030 - cr01.sctg35.wum.118 - CRE01030.1 - RP10783 - CRE01030 taxonomy: c_remanei other_names: - CRE01030 - cr01.sctg35.wum.118 - CRE01030.1 - RP10783 - CRE01030 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00063074 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18. label: CRE20584 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18. id: WBGene00082609 label: CRE20584 other_names: - CRE20584 - CRE20584.1 - CRE20584 - RP37884 taxonomy: c_remanei other_names: - CRE20584 - CRE20584.1 - CRE20584 - RP37884 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00082609 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans syx-18. label: Ppa-syx-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans syx-18. id: WBGene00101324 label: Ppa-syx-18 other_names: - PPA11770 - GENEPREDICTION_SNAP300000068211 - GENEPREDICTION_SNAP300000068212 - UMM-S278-3.43 - PPA11770.1 - PPA11770 - PP74379 taxonomy: p_pacificus other_names: - PPA11770 - GENEPREDICTION_SNAP300000068211 - GENEPREDICTION_SNAP300000068212 - UMM-S278-3.43 - PPA11770.1 - PPA11770 - PP74379 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00101324 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans tag-18. label: PPA07496 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tag-18. id: WBGene00097050 label: PPA07496 other_names: - PPA07496 - GENEPREDICTION_SNAP300000063972 - Ppa-tag-18 - UMM-S419-1.46 - PPA07496 - PPA07496.1 - PP68341 taxonomy: p_pacificus other_names: - PPA07496 - GENEPREDICTION_SNAP300000063972 - Ppa-tag-18 - UMM-S419-1.46 - PPA07496 - PPA07496.1 - PP68341 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00097050 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans tag-18. label: SRAE_X000218200 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tag-18. id: WBGene00267760 label: SRAE_X000218200 other_names: - SRAE_X000218200 - SRP10981 - SRAE_X000218200.1 - SRAE_X000218200 taxonomy: s_ratti other_names: - SRAE_X000218200 - SRP10981 - SRAE_X000218200.1 - SRAE_X000218200 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00267760 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans mab-3. In C. elegans, mab-3 is involved in negative regulation of transcription by RNA polymerase II; nematode male tail tip morphogenesis; and positive regulation of nematode male tail tip morphogenesis. label: CBG01044 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-3. - In C. elegans, mab-3 is involved in negative regulation of transcription by RNA polymerase II; nematode id: WBGene00024335 label: CBG01044 other_names: - CBG01044 - CBG_01044 - CBG01044 taxonomy: c_briggsae other_names: - CBG01044 - CBG_01044 - CBG01044 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00024335 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.18. label: CBG07851 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.18. id: WBGene00029764 label: CBG07851 other_names: - CBG07851 - CBG_07851 - CBG07851.1 - CBG07851 - CBP07858 taxonomy: c_briggsae other_names: - CBG07851 - CBG_07851 - CBG07851.1 - CBG07851 - CBP07858 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00029764 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.18. label: CBG18667 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.18. id: WBGene00038046 label: CBG18667 other_names: - CBG18667 - CBG_18667 - CBG18667.1 - CBP23779 - CBG18667 taxonomy: c_briggsae other_names: - CBG18667 - CBG_18667 - CBG18667.1 - CBP23779 - CBG18667 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00038046 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.18. label: CBN22301 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.18. id: WBGene00161026 label: CBN22301 other_names: - CBN22301 - CBN22301 - CBN22301.1 - CN08136 taxonomy: c_brenneri other_names: - CBN22301 - CBN22301 - CBN22301.1 - CN08136 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00161026 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nlp-18. label: Cbr-nlp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nlp-18. id: WBGene00025937 label: Cbr-nlp-18 other_names: - CBG02983 - CBG_02983 - CBP06397 - CBG02983.1 - CBG02983 taxonomy: c_briggsae other_names: - CBG02983 - CBG_02983 - CBP06397 - CBG02983.1 - CBG02983 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00025937 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans syx-18. label: Cre-syx-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans syx-18. id: WBGene00052198 label: Cre-syx-18 other_names: - CRE31150 - cr01.sctg1.wum.86 - CRE31150.1 - RP40824 - CRE31150 taxonomy: c_remanei other_names: - CRE31150 - cr01.sctg1.wum.86 - CRE31150.1 - RP40824 - CRE31150 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00052198 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18. label: CRE16094 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18. id: WBGene00082056 label: CRE16094 other_names: - CRE16094 - CRE16094.1 - RP29286 - CRE16094 taxonomy: c_remanei other_names: - CRE16094 - CRE16094.1 - RP29286 - CRE16094 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00082056 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18. label: CRE19496 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18. id: WBGene00081776 label: CRE19496 other_names: - CRE19496 - CRE19496 - CRE19496.1 - RP34253 taxonomy: c_remanei other_names: - CRE19496 - CRE19496 - CRE19496.1 - RP34253 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00081776 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans ctf-18. label: CRE29989 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ctf-18. id: WBGene00074058 label: CRE29989 other_names: - CRE29989 - cr01.sctg1049.wum.6 - CRE29989.1 - RP45394 - CRE29989 taxonomy: c_remanei other_names: - CRE29989 - cr01.sctg1049.wum.6 - CRE29989.1 - RP45394 - CRE29989 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00074058 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans cpg-18. label: CRE30540 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans cpg-18. id: WBGene00073103 label: CRE30540 other_names: - CRE30540 - cr01.sctg594.wum.6 - CRE30540.1 - RP12957 - CRE30540 taxonomy: c_remanei other_names: - CRE30540 - cr01.sctg594.wum.6 - CRE30540.1 - RP12957 - CRE30540 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00073103 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans syx-18. label: Bma-syx-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans syx-18. id: WBGene00225982 label: Bma-syx-18 other_names: - Bm5721 - Bm1_53070 - TAG12049 - TAG5721 - Bm5721.1 - BM37323 - Bm5721 taxonomy: b_malayi other_names: - Bm5721 - Bm1_53070 - TAG12049 - TAG5721 - Bm5721.1 - BM37323 - Bm5721 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00225982 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans tag-18. label: CBG14278 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tag-18. id: WBGene00034832 label: CBG14278 other_names: - CBG14278 - Cbr-tag-18 - CBG_14278 - CBG14278 - CBP03593 - CBG14278.1 taxonomy: c_briggsae other_names: - CBG14278 - Cbr-tag-18 - CBG_14278 - CBG14278 - CBP03593 - CBG14278.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00034832 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans cpg-18. label: Cbn-cpg-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans cpg-18. id: WBGene00162124 label: Cbn-cpg-18 other_names: - CBN23399 - CN29742 - CBN23399.1 - CBN23399 taxonomy: c_brenneri other_names: - CBN23399 - CN29742 - CBN23399.1 - CBN23399 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00162124 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans pqn-18. label: Cbn-pqn-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans pqn-18. id: WBGene00155198 label: Cbn-pqn-18 other_names: - CBN16473 - CBN16473 - CBN16473 - CBN16473.1 - CN07836 taxonomy: c_brenneri other_names: - CBN16473 - CBN16473 - CBN16473 - CBN16473.1 - CN07836 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00155198 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans ctf-18. label: CBN21901 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ctf-18. id: WBGene00160626 label: CBN21901 other_names: - CBN21901 - CBN21901 - CN28756 - CBN21901.1 taxonomy: c_brenneri other_names: - CBN21901 - CBN21901 - CN28756 - CBN21901.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00160626 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans syx-18. label: Cbr-syx-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans syx-18. id: WBGene00038276 label: Cbr-syx-18 other_names: - CBG18985 - CBG_18985 - CBP19514 - CBG18985 - CBG18985.1 taxonomy: c_briggsae other_names: - CBG18985 - CBG_18985 - CBP19514 - CBG18985 - CBG18985.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00038276 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans tag-18. label: CJA09850 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tag-18. id: WBGene00129054 label: CJA09850 other_names: - CJA09850 - Cjp-tag-18 - JA09239 - CJA09850.1 - CJA09850 taxonomy: c_japonica other_names: - CJA09850 - Cjp-tag-18 - JA09239 - CJA09850.1 - CJA09850 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00129054 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans dct-18. label: Cjp-dct-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dct-18. id: WBGene00125216 label: Cjp-dct-18 other_names: - CJA06012 - CJA06012b - CJA06012a.1 - CJA06012a - JA46248 - JA39527 - CJA06012b.1 taxonomy: c_japonica other_names: - CJA06012 - CJA06012b - CJA06012a.1 - CJA06012a - JA46248 - JA39527 - CJA06012b.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00125216 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans pqn-18. label: Cjp-pqn-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans pqn-18. id: WBGene00126583 label: Cjp-pqn-18 other_names: - CJA07379 - CJA07379 - CJA07379.1 - JA55680 taxonomy: c_japonica other_names: - CJA07379 - CJA07379 - CJA07379.1 - JA55680 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00126583 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans txt-18. label: Cre-txt-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans txt-18. id: WBGene00054059 label: Cre-txt-18 other_names: - CRE26549 - cr01.sctg3.wum.80 - CRE26549.1 - RP00055 - CRE26549 taxonomy: c_remanei other_names: - CRE26549 - cr01.sctg3.wum.80 - CRE26549.1 - RP00055 - CRE26549 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00054059 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans irld-18. label: CRE03484 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans irld-18. id: WBGene00071428 label: CRE03484 other_names: - CRE03484 - cr01.sctg251.wum.20 - CRE03484.1 - RP18124 - CRE03484 taxonomy: c_remanei other_names: - CRE03484 - cr01.sctg251.wum.20 - CRE03484.1 - RP18124 - CRE03484 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00071428 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18. label: CRE19543 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18. id: WBGene00075745 label: CRE19543 other_names: - CRE19543 - cr01.sctg2842.wum.1 - CRE19543 - CRE19543.1 - RP42726 taxonomy: c_remanei other_names: - CRE19543 - cr01.sctg2842.wum.1 - CRE19543 - CRE19543.1 - RP42726 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00075745 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y75B8A.18. label: CRE24395 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y75B8A.18. id: WBGene00083027 label: CRE24395 other_names: - CRE24395 - CRE24395.1 - CRE24395 - RP42076 taxonomy: c_remanei other_names: - CRE24395 - CRE24395.1 - CRE24395 - RP42076 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00083027 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y75B8A.18. label: CBG23050 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y75B8A.18. id: WBGene00041476 label: CBG23050 other_names: - CBG23050 - CBG_23050 - CBG23050.1 - CBG23050 - CBP20566 taxonomy: c_briggsae other_names: - CBG23050 - CBG_23050 - CBG23050.1 - CBG23050 - CBP20566 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00041476 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans dct-18. label: Cbn-dct-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dct-18. id: WBGene00150197 label: Cbn-dct-18 other_names: - CBN11472 - CBN11472.1 - CBN11472 - CN28809 taxonomy: c_brenneri other_names: - CBN11472 - CBN11472.1 - CBN11472 - CN28809 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00150197 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans tag-18. label: CBN00130 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tag-18. id: WBGene00138855 label: CBN00130 other_names: - CBN00130 - Cbn-tag-18 - CN28095 - CBN00130.1 - CBN00130 taxonomy: c_brenneri other_names: - CBN00130 - Cbn-tag-18 - CN28095 - CBN00130.1 - CBN00130 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00138855 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y75B8A.18. label: CBN10540 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y75B8A.18. id: WBGene00149265 label: CBN10540 other_names: - CBN10540 - CBN10540.1 - CBN10540 - CN31425 taxonomy: c_brenneri other_names: - CBN10540 - CBN10540.1 - CBN10540 - CN31425 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00149265 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans dct-18. label: Cbr-dct-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dct-18. id: WBGene00025750 label: Cbr-dct-18 other_names: - CBG02759 - CBG_02759 - CBG02759a - CBG02759b - CBP00814 - CBG02759a.1 - CBG02759b.1 taxonomy: c_briggsae other_names: - CBG02759 - CBG_02759 - CBG02759a - CBG02759b - CBP00814 - CBG02759a.1 - CBG02759b.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00025750 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans pqn-18. label: Cbr-pqn-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans pqn-18. id: WBGene00023552 label: Cbr-pqn-18 other_names: - CBG00045 - CBG_00045 - CBG00045.1 - CBG00045 - CBP29904 taxonomy: c_briggsae other_names: - CBG00045 - CBG_00045 - CBG00045.1 - CBG00045 - CBP29904 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00023552 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans txt-18. label: Cjp-txt-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans txt-18. id: WBGene00121081 label: Cjp-txt-18 other_names: - CJA01877 - CJA01877 - JA57015 - CJA01877.1 taxonomy: c_japonica other_names: - CJA01877 - CJA01877 - JA57015 - CJA01877.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00121081 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans cpg-18. label: Cre-cpg-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans cpg-18. id: WBGene00063960 label: Cre-cpg-18 other_names: - CRE28765 - cr01.sctg44.wum.23 - CRE28765 - RP12957 - CRE28765.1 taxonomy: c_remanei other_names: - CRE28765 - cr01.sctg44.wum.23 - CRE28765 - RP12957 - CRE28765.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00063960 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans dct-18. label: Cre-dct-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dct-18. id: WBGene00053677 label: Cre-dct-18 other_names: - CRE01690 - cr01.sctg2.wum.458 - CRE01690 - CRE01690.1 - RP02643 taxonomy: c_remanei other_names: - CRE01690 - cr01.sctg2.wum.458 - CRE01690 - CRE01690.1 - RP02643 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00053677 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans syx-18. label: Ovo-syx-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans syx-18. id: WBGene00243044 label: Ovo-syx-18 other_names: - OVOC6235 - OVOC6235.1 - OVP03368 - OVOC6235 taxonomy: o_volvulus other_names: - OVOC6235 - OVOC6235.1 - OVP03368 - OVOC6235 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00243044 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans dct-18. label: Ppa-dct-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dct-18. id: WBGene00101479 label: Ppa-dct-18 other_names: - PPA11925 - GENEPREDICTION_SNAP300000068368 - UMM-S41-12.51 - PPA11925 - PPA11925.1 - PP04099 taxonomy: p_pacificus other_names: - PPA11925 - GENEPREDICTION_SNAP300000068368 - UMM-S41-12.51 - PPA11925 - PPA11925.1 - PP04099 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00101479 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans ztf-18. label: Ppa-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00203876 label: Ppa-ztf-18 other_names: - PPA31011 - UMM-S13-7.60 - PPA31011 - PP66715 - PPA31011.1 taxonomy: p_pacificus other_names: - PPA31011 - UMM-S13-7.60 - PPA31011 - PP66715 - PPA31011.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00203876 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans dct-18. label: SRAE_X000227900 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dct-18. id: WBGene00267861 label: SRAE_X000227900 other_names: - SRAE_X000227900 - SR00101 - SRP01513 - SRAE_X000227900 - SRAE_X000227900.1 taxonomy: s_ratti other_names: - SRAE_X000227900 - SR00101 - SRP01513 - SRAE_X000227900 - SRAE_X000227900.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00267861 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: Cbr-mig-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00040061 label: Cbr-mig-18 other_names: - CBG21220 - CBG_21220 - CBP32662 - CBG21220 - CBG21220.1 taxonomy: c_briggsae other_names: - CBG21220 - CBG_21220 - CBP32662 - CBG21220 - CBG21220.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00040061 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: Cjp-mig-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00119230 label: Cjp-mig-18 other_names: - CJA00026 - JA46931 - CJA00026a.1 - JA67456 - CJA00026b - CJA00026a - CJA00026b.1 taxonomy: c_japonica other_names: - CJA00026 - JA46931 - CJA00026a.1 - JA67456 - CJA00026b - CJA00026a - CJA00026b.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00119230 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: Cre-mig-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00061929 label: Cre-mig-18 other_names: - CRE14974 - cr01.sctg27.wum.110 - RP03631 - CRE14974 - CRE14974.1 taxonomy: c_remanei other_names: - CRE14974 - cr01.sctg27.wum.110 - RP03631 - CRE14974 - CRE14974.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00061929 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: OVOC7162 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00243971 label: OVOC7162 other_names: - OVOC7162 - OVOC7162.1 - OVOC7162 - OVP09295 taxonomy: o_volvulus other_names: - OVOC7162 - OVOC7162.1 - OVOC7162 - OVP09295 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00243971 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: Ppa-mig-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00278158 label: Ppa-mig-18 other_names: - PPA39789 - PPA39789.1 - PP62349 - PPA39789 taxonomy: p_pacificus other_names: - PPA39789 - PPA39789.1 - PP62349 - PPA39789 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00278158 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.18. label: CBG01312 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.18. id: WBGene00024570 label: CBG01312 other_names: - CBG01312 - CBG_01312 - CBP05969 - CBG01312.1 - CBG01312 taxonomy: c_briggsae other_names: - CBG01312 - CBG_01312 - CBP05969 - CBG01312.1 - CBG01312 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00024570 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nlp-18. label: Cbn-nlp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nlp-18. id: WBGene00157540 label: Cbn-nlp-18 other_names: - CBN18815 - CBN18815 - CBN18815 - CN25415 - CBN18815.1 taxonomy: c_brenneri other_names: - CBN18815 - CBN18815 - CBN18815 - CN25415 - CBN18815.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00157540 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y75B8A.18. label: CJA04028 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y75B8A.18. id: WBGene00123232 label: CJA04028 other_names: - CJA04028 - JA12793 - CJA04028 - CJA04028.1 taxonomy: c_japonica other_names: - CJA04028 - JA12793 - CJA04028 - CJA04028.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00123232 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y82E9BR.18. label: CJA22269 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y82E9BR.18. id: WBGene00177841 label: CJA22269 other_names: - CJA22269 - JA63971 - CJA22269b.1 - CJA22269b - CJA22269a.1 - CJA22269a - JA53784 taxonomy: c_japonica other_names: - CJA22269 - JA63971 - CJA22269b.1 - CJA22269b - CJA22269a.1 - CJA22269a - JA53784 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00177841 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans cpg-18. label: Cjp-cpg-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans cpg-18. id: WBGene00131360 label: Cjp-cpg-18 other_names: - CJA12156 - JA31315 - CJA12156.1 - CJA12156 taxonomy: c_japonica other_names: - CJA12156 - JA31315 - CJA12156.1 - CJA12156 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00131360 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nlp-18. label: Cjp-nlp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nlp-18. id: WBGene00179702 label: Cjp-nlp-18 other_names: - CJA24130 - CJA24130.1 - CJA24130 - JA57705 taxonomy: c_japonica other_names: - CJA24130 - CJA24130.1 - CJA24130 - JA57705 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00179702 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y43F8B.18. label: CRE26920 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y43F8B.18. id: WBGene00081607 label: CRE26920 other_names: - CRE26920 - RP46112 - CRE26920.1 - CRE26920 taxonomy: c_remanei other_names: - CRE26920 - RP46112 - CRE26920.1 - CRE26920 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00081607 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: Cbn-mig-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00161454 label: Cbn-mig-18 other_names: - CBN22729 - CBN22729.1 - CBN22729 - CN05084 taxonomy: c_brenneri other_names: - CBN22729 - CBN22729.1 - CBN22729 - CN05084 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00161454 - allele: - class: variation id: WBVar00142158 label: cxTi9674 - class: variation id: WBVar00922816 label: gk483048 - class: variation id: WBVar00429207 label: gk205964 - class: variation id: WBVar00429205 label: gk205962 - class: variation id: WBVar00922815 label: gk635729 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00922817 label: gk683530 - class: variation id: WBVar00429202 label: gk205959 - class: variation id: WBVar00429203 label: gk205960 - class: variation id: WBVar00429208 label: gk205965 - class: variation id: WBVar00922824 label: gk789094 - class: variation id: WBVar00922823 label: gk563064 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00429206 label: gk205963 - class: variation id: WBVar00922825 label: gk866119 - class: variation id: WBVar00922820 label: gk659942 - class: variation id: WBVar00922819 label: gk549234 - class: variation id: WBVar00922821 label: gk482061 - class: variation id: WBVar00429209 label: gk205966 - class: variation id: WBVar00429204 label: gk205961 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00922822 label: gk898752 - class: variation id: WBVar01499395 label: gk963416 - class: variation id: WBVar00922818 label: gk670004 - class: variation id: WBVar01499396 label: gk963417 - class: variation id: WBVar00093938 label: ok2843 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. Is an ortholog of human DEGS1 (delta 4-desaturase, sphingolipid 1) and DEGS2 (delta 4-desaturase, sphingolipid 2). label: F33D4.4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. id: WBGene00017996 label: F33D4.4 other_names: - F33D4.4 - CELE_F33D4.4 - F33D4.4.2 - F33D4.4.1 - F33D4.4 - CE17034 taxonomy: c_elegans other_names: - F33D4.4 - CELE_F33D4.4 - F33D4.4.2 - F33D4.4.1 - F33D4.4 - CE17034 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00017996 - allele: - class: variation id: WBVar01498685 label: gk963922 - class: variation id: WBVar01498375 label: gk962890 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar01499023 label: gk962809 - class: variation id: WBVar01498726 label: gk964133 - class: variation id: WBVar01500260 label: gk964518 - class: variation id: WBVar01498673 label: gk963858 - class: variation id: WBVar00145309 label: f122 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by several genes including daf-18; csr-1; and nhr-8 based on RNA-seq and microarray studies. Is affected by methylmercury hydroxide based on RNA-seq studies. Is predicted to encode a protein with the following domains: Tight junction protein, Claudin-like and Tight junction protein, claudin-like." label: ZC262.10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-18; csr-1; and nhr-8 based on RNA-seq and microarray studies id: WBGene00044802 label: ZC262.10 other_names: - ZC262.10 - CELE_ZC262.10 - ZC262.10.1 - CE46066 - ZC262.10 taxonomy: c_elegans other_names: - ZC262.10 - CELE_ZC262.10 - ZC262.10.1 - CE46066 - ZC262.10 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00044802 - allele: - class: variation id: WBVar00934531 label: gk862749 - class: variation id: WBVar00433005 label: gk209762 - class: variation id: WBVar00934521 label: gk856433 - class: variation id: WBVar00934522 label: gk653798 - class: variation id: WBVar00934525 label: gk811668 - class: variation id: WBVar01500039 label: gk964227 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar00433004 label: gk209761 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00934530 label: gk583078 - class: variation id: WBVar00934528 label: gk816282 - class: variation id: WBVar00934527 label: gk366424 - class: variation id: WBVar00433007 label: gk209764 - class: variation id: WBVar00433003 label: gk209760 - class: variation id: WBVar01500079 label: gk964278 - class: variation id: WBVar00433006 label: gk209763 - class: variation id: WBVar00934523 label: gk463509 - class: variation id: WBVar00934534 label: gk459942 - class: variation id: WBVar00934533 label: gk781822 - class: variation id: WBVar00934524 label: gk783780 - class: variation id: WBVar01482263 label: gk946523 - class: variation id: WBVar01500038 label: gk964226 - class: variation id: WBVar02134478 label: h8772 - class: variation id: WBVar00934532 label: gk778131 - class: variation id: WBVar00934529 label: gk652665 - class: variation id: WBVar00934526 label: gk531124 - class: variation id: WBVar00934520 label: gk811667 - class: variation id: WBVar01498996 label: gk962765 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in generation of catalytic spliceosome for second transesterification step. Predicted to be located in nuclear speck. Predicted to be part of U2-type post-spliceosomal complex; U4/U6 x U5 tri-snRNP complex; and U5 snRNP. Is an ortholog of human PRPF18 (pre-mRNA processing factor 18). label: prp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human PRPF18 (pre-mRNA processing factor 18). id: WBGene00009320 label: prp-18 other_names: - F32B6.3 - CELE_F32B6.3 - F32B6.3.1 - F32B6.3 - F32B6.3.2 - CE35518 taxonomy: c_elegans other_names: - F32B6.3 - CELE_F32B6.3 - F32B6.3.1 - F32B6.3 - F32B6.3.2 - CE35518 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00009320 - allele: - class: variation id: WBVar00693326 label: gk815853 - class: variation id: WBVar00693334 label: gk787746 - class: variation id: WBVar00693343 label: gk515832 - class: variation id: WBVar00693351 label: gk331296 - class: variation id: WBVar00353015 label: gk129772 - class: variation id: WBVar00693344 label: gk630455 - class: variation id: WBVar00093280 label: ok2095 - class: variation id: WBVar00353020 label: gk129777 - class: variation id: WBVar00693329 label: gk929735 - class: variation id: WBVar00693336 label: gk749740 - class: variation id: WBVar00693325 label: gk806337 - class: variation id: WBVar00693347 label: gk335385 - class: variation id: WBVar00693338 label: gk811998 - class: variation id: WBVar00693352 label: gk504683 - class: variation id: WBVar00353017 label: gk129774 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar00353018 label: gk129775 - class: variation id: WBVar00693350 label: gk676812 - class: variation id: WBVar00693354 label: gk871825 - class: variation id: WBVar00693339 label: gk852790 - class: variation id: WBVar00693330 label: gk901015 - class: variation id: WBVar00693345 label: gk376815 - class: variation id: WBVar00693333 label: gk492515 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00693346 label: gk365580 - class: variation id: WBVar01499823 label: gk963947 - class: variation id: WBVar00353016 label: gk129773 - class: variation id: WBVar00693353 label: gk589756 - class: variation id: WBVar00693331 label: gk324321 - class: variation id: WBVar00693328 label: gk364214 - class: variation id: WBVar00693341 label: gk773855 - class: variation id: WBVar00693348 label: gk934943 - class: variation id: WBVar01498939 label: gk962681 - class: variation id: WBVar00693327 label: gk666957 - class: variation id: WBVar00353021 label: gk129778 - class: variation id: WBVar00693335 label: gk749739 - class: variation id: WBVar02125250 label: tm6585 - class: variation id: WBVar00693332 label: gk722002 - class: variation id: WBVar00353014 label: gk129771 - class: variation id: WBVar00693337 label: gk725798 - class: variation id: WBVar00693349 label: gk468101 - class: variation id: WBVar01499298 label: gk963269 - class: variation id: WBVar00353019 label: gk129776 - class: variation id: WBVar00693340 label: gk710991 - class: variation id: WBVar00693342 label: gk795770 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sphingolipid delta-4 desaturase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. Is an ortholog of human DEGS1 (delta 4-desaturase, sphingolipid 1) and DEGS2 (delta 4-desaturase, sphingolipid 2). label: ttm-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Human ortholog(s) of this gene implicated in hypomyelinating leukodystrophy 18. id: WBGene00013197 label: ttm-5 other_names: - Y54E5A.1 - CELE_Y54E5A.1 - Y105E8B.o - CE28791 - Y54E5A.1.1 - Y54E5A.1.2 - Y54E5A.1 taxonomy: c_elegans other_names: - Y54E5A.1 - CELE_Y54E5A.1 - Y105E8B.o - CE28791 - Y54E5A.1.1 - Y54E5A.1.2 - Y54E5A.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00013197 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Acts upstream of or within nematode male tail tip morphogenesis. label: erf-1 legacy_description: erf-1 was identified in screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab-20/semaphorin-2A; erf-1 is defined by a single mutation and likely functions in the same pathway as erf-2, and in a parallel pathway to plx-2, to regulate ray cell sorting. merged_into: ~ name: class: gene highlight: description_all: - screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab id: WBGene00007031 label: erf-1 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007031 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans flp-18. In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. label: Cjp-flp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans flp-18. - In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction id: WBGene00130040 label: Cjp-flp-18 other_names: - CJA10836 - CJA10836 - CJA10836.1 - JA05942 taxonomy: c_japonica other_names: - CJA10836 - CJA10836 - CJA10836.1 - JA05942 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00130040 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Acts upstream of or within nematode male tail tip morphogenesis. label: erf-2 legacy_description: erf-2 was identified in screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab-20/semaphorin-2A; erf-2 is defined by a single mutation and likely functions in the same pathway as erf-1, and in a parallel pathway to plx-2, to regulate ray cell sorting. merged_into: ~ name: class: gene highlight: description_all: - screens for mutations that enhance male sensory ray cell sorting defects produced by a weak mutation in mab id: WBGene00007032 label: erf-2 other_names: - ~ taxonomy: c_elegans other_names: - ~ page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007032 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of O. volvulus Ovo-flp-18. label: Bm18003 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of O. volvulus Ovo-flp-18. id: WBGene00269145 label: Bm18003 other_names: - Bm18003 - Bm18003.1 - BM43684 - Bm18003 taxonomy: b_malayi other_names: - Bm18003 - Bm18003.1 - BM43684 - Bm18003 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00269145 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans him-18. In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid segregation. label: Cbr-him-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans him-18. - In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid id: WBGene00037501 label: Cbr-him-18 other_names: - CBG18002 - CBG_18002 - CBG18002a.1 - CBG18002b.1 - CBP42184 - CBG18002b - CBP19137 - CBG18002a - CBG18002b.2 taxonomy: c_briggsae other_names: - CBG18002 - CBG_18002 - CBG18002a.1 - CBG18002b.1 - CBP42184 - CBG18002b - CBP19137 - CBG18002a - CBG18002b.2 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00037501 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans him-18. In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid segregation. label: Ppa-him-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans him-18. - In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid id: WBGene00275153 label: Ppa-him-18 other_names: - PPA36784 - PPA36784 - PP75098 - PPA36784.1 taxonomy: p_pacificus other_names: - PPA36784 - PPA36784 - PP75098 - PPA36784.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00275153 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Bma-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00231437 label: Bma-ptr-18 other_names: - Bm11176 - Bm-ptr-18 - Bm1_25710 - TAG6427 - TAG11176 - Bm1_25710A - BM31395 - Bm11176a.1 - Bm11176b - BM28904 - Bm11176b.1 - Bm11176a taxonomy: b_malayi other_names: - Bm11176 - Bm-ptr-18 - Bm1_25710 - TAG6427 - TAG11176 - Bm1_25710A - BM31395 - Bm11176a.1 - Bm11176b - BM28904 - Bm11176b.1 - Bm11176a page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00231437 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Cbn-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00162620 label: Cbn-ptr-18 other_names: - CBN23895 - CBN23895 - CN04885 - CBN23895.1 - CBN23895 taxonomy: c_brenneri other_names: - CBN23895 - CBN23895 - CN04885 - CBN23895.1 - CBN23895 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00162620 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: CBN00241 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00138966 label: CBN00241 other_names: - CBN00241 - CBN00241.1 - CN26185 - CBN00241 taxonomy: c_brenneri other_names: - CBN00241 - CBN00241.1 - CN26185 - CBN00241 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00138966 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans him-18. In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid segregation. label: Cjp-him-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans him-18. - In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid id: WBGene00137506 label: Cjp-him-18 other_names: - CJA18302 - CJA18302 - CJA18302.1 - JA55010 taxonomy: c_japonica other_names: - CJA18302 - CJA18302 - CJA18302.1 - JA55010 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00137506 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Cre-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00053670 label: Cre-ptr-18 other_names: - CRE01695 - cr01.sctg2.wum.451 - RP45502 - CRE01695 - CRE01695.1 taxonomy: c_remanei other_names: - CRE01695 - cr01.sctg2.wum.451 - RP45502 - CRE01695 - CRE01695.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00053670 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Cbr-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00025756 label: Cbr-ptr-18 other_names: - CBG02766 - CBG_02766 - CBG02766.1 - CBP43528 - CBG02766 taxonomy: c_briggsae other_names: - CBG02766 - CBG_02766 - CBG02766.1 - CBP43528 - CBG02766 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00025756 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Cjp-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00122729 label: Cjp-ptr-18 other_names: - CJA03525 - JA50755 - CJA03525.1 - CJA03525 taxonomy: c_japonica other_names: - CJA03525 - JA50755 - CJA03525.1 - CJA03525 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00122729 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans him-18. In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid segregation. label: Cre-him-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans him-18. - In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid id: WBGene00082234 label: Cre-him-18 other_names: - CRE20236 - CRE20236.1 - CRE20236 - RP36441 taxonomy: c_remanei other_names: - CRE20236 - CRE20236.1 - CRE20236 - RP36441 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00082234 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans him-18. In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid segregation. label: Cbn-him-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans him-18. - In C. elegans, him-18 is involved in DNA metabolic process; embryo development; and mitotic sister chromatid id: WBGene00145736 label: Cbn-him-18 other_names: - CBN07011 - CBN07011.1 - CBN07011 - CN28836 taxonomy: c_brenneri other_names: - CBN07011 - CBN07011.1 - CBN07011 - CN28836 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00145736 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Ovo-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00247034 label: Ovo-ptr-18 other_names: - OVOC10225 - OVOC10225 - OVP08766 - OVOC10225.1 taxonomy: o_volvulus other_names: - OVOC10225 - OVOC10225 - OVP08766 - OVOC10225.1 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00247034 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: Ppa-ptr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00098719 label: Ppa-ptr-18 other_names: - PPA09165 - UMS-S10-86.57 - GENEPREDICTION_SNAP300000065703 - PP54760 - PPA09165 - PPA09165.1 taxonomy: p_pacificus other_names: - PPA09165 - UMS-S10-86.57 - GENEPREDICTION_SNAP300000065703 - PP54760 - PPA09165 - PPA09165.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00098719 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans ptr-18. In C. elegans, ptr-18 is involved in endocytosis and molting cycle. label: SRAE_X000037000 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ptr-18. - In C. elegans, ptr-18 is involved in endocytosis and molting cycle. id: WBGene00265929 label: SRAE_X000037000 other_names: - SRAE_X000037000 - SRAE_X000037000 - SRP10716 - SRAE_X000037000.1 taxonomy: s_ratti other_names: - SRAE_X000037000 - SRAE_X000037000 - SRP10716 - SRAE_X000037000.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00265929 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Orthologous to human MB21D2 (Mab-21 domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cobalt dichloride. label: Mb21d2 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Orthologous to human MB21D2 (Mab-21 domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine id: RGD:1559643 label: Mb21d2 other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:1559643 - allele: - class: variation id: WBVar01157195 label: gk542010 - class: variation id: WBVar00507137 label: gk283894 - class: variation id: WBVar01157192 label: gk916727 - class: variation id: WBVar01157191 label: gk319742 - class: variation id: WBVar01498964 label: gk962713 - class: variation id: WBVar00507134 label: gk283891 - class: variation id: WBVar00507135 label: gk283892 - class: variation id: WBVar01157194 label: gk681966 - class: variation id: WBVar01157193 label: gk779845 - class: variation id: WBVar00507136 label: gk283893 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar00507138 label: gk283895 - class: variation id: WBVar01157190 label: gk625569 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in ABplpppaaa and ABprpppaaa based on single-cell RNA-seq studies. Is affected by several genes including daf-16; nhr-49; and daf-18 based on microarray and RNA-seq studies. Is affected by ten chemicals including multi-walled carbon nanotube; stavudine; and Rifampin based on RNA-seq and microarray studies. label: F41C6.6 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; nhr-49; and daf-18 based on microarray and RNA-seq studies id: WBGene00018279 label: F41C6.6 other_names: - F41C6.6 - CELE_F41C6.6 - F41C6.6 - F41C6.6.1 - CE04543 taxonomy: c_elegans other_names: - F41C6.6 - CELE_F41C6.6 - F41C6.6 - F41C6.6.1 - CE04543 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00018279 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: CBG00043 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00023551 label: CBG00043 other_names: - CBG00043 - CBG_00043 - CBP47835 - CBG00043.1 - CBG00043 taxonomy: c_briggsae other_names: - CBG00043 - CBG_00043 - CBP47835 - CBG00043.1 - CBG00043 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00023551 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: SRAE_1000326000 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00259877 label: SRAE_1000326000 other_names: - SRAE_1000326000 - SRAE_1000326000 - SRAE_1000326000.1 - SRP03502 taxonomy: s_ratti other_names: - SRAE_1000326000 - SRAE_1000326000 - SRAE_1000326000.1 - SRP03502 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00259877 - allele: - class: variation id: WBVar00994287 label: gk418878 - class: variation id: WBVar01499740 label: gk963850 - class: variation id: WBVar01499528 label: gk963591 - class: variation id: WBVar00994292 label: gk616806 - class: variation id: WBVar00994294 label: gk343663 - class: variation id: WBVar01499167 label: gk963027 - class: variation id: WBVar00994290 label: gk917929 - class: variation id: WBVar00994291 label: gk765878 - class: variation id: WBVar01498944 label: gk962689 - class: variation id: WBVar00994284 label: gk895628 - class: variation id: WBVar00994293 label: gk521172 - class: variation id: WBVar00994285 label: gk685699 - class: variation id: WBVar00994289 label: gk331813 - class: variation id: WBVar01499496 label: gk963553 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01500066 label: gk964259 - class: variation id: WBVar00994295 label: gk742976 - class: variation id: WBVar00994286 label: gk550186 - class: variation id: WBVar00452536 label: gk229293 - class: variation id: WBVar01498943 label: gk962688 - class: variation id: WBVar00994288 label: gk606489 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of human HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14). label: dhs-14 legacy_description: dhs-14 encodes a short chain-type of alcohol/other dehydrogenase, more similar to 18 paralogs in C. elegans than to any non-worm protein; it is dispensable for viability and gross morphology in mass RNAi screens. merged_into: ~ name: class: gene highlight: description_all: - dhs-14 encodes a short chain-type of alcohol/other dehydrogenase, more similar to 18 paralogs in C. elegans id: WBGene00000977 label: dhs-14 other_names: - R05D8.8 - CELE_R05D8.8 - R05D8.8.1 - R05D8.8 - CE23899 taxonomy: c_elegans other_names: - R05D8.8 - CELE_R05D8.8 - R05D8.8.1 - R05D8.8 - CE23899 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000977 - allele: - class: variation id: WBVar00644164 label: gk547269 - class: variation id: WBVar00146602 label: h490 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar00644173 label: gk573662 - class: variation id: WBVar00644184 label: gk487942 - class: variation id: WBVar00146526 label: h293 - class: variation id: WBVar00644180 label: gk340331 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar00644182 label: gk421263 - class: variation id: WBVar00644174 label: gk322846 - class: variation id: WBVar00336357 label: gk113114 - class: variation id: WBVar00644181 label: gk396324 - class: variation id: WBVar00644167 label: gk451781 - class: variation id: WBVar00644169 label: gk603896 - class: variation id: WBVar00644165 label: gk914948 - class: variation id: WBVar00336354 label: gk113111 - class: variation id: WBVar00644183 label: gk430218 - class: variation id: WBVar00644170 label: gk884695 - class: variation id: WBVar00249961 label: tm939 - class: variation id: WBVar00644166 label: gk634116 - class: variation id: WBVar02127630 label: h7333 - class: variation id: WBVar00644179 label: gk368704 - class: variation id: WBVar00644176 label: gk523822 - class: variation id: WBVar00336356 label: gk113113 - class: variation id: WBVar00336358 label: gk113115 - class: variation id: WBVar00644175 label: gk748636 - class: variation id: WBVar02127629 label: h7332 - class: variation id: WBVar00644171 label: gk689067 - class: variation id: WBVar00644172 label: gk911539 - class: variation id: WBVar00644177 label: gk871773 - class: variation id: WBVar00644163 label: gk494405 - class: variation id: WBVar00644168 label: gk494012 - class: variation id: WBVar00644178 label: gk888855 - class: variation id: WBVar00336355 label: gk113112 - class: variation id: WBVar01499786 label: gk963902 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II and termination of RNA polymerase II transcription. Predicted to be located in nucleus. Predicted to be part of core mediator complex and mediator complex. Is an ortholog of human MED18 (mediator complex subunit 18). label: mdt-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human MED18 (mediator complex subunit 18). id: WBGene00007018 label: mdt-18 other_names: - C55B7.9 - let-604 - CELE_C55B7.9 - C55B7.9a.1 - CE09020 - C55B7.9b - C55B7.9a - C55B7.9a.2 - C55B7.9b.1 - CE51480 - C55B7.9a.3 taxonomy: c_elegans other_names: - C55B7.9 - let-604 - CELE_C55B7.9 - C55B7.9a.1 - CE09020 - C55B7.9b - C55B7.9a - C55B7.9a.2 - C55B7.9b.1 - CE51480 - C55B7.9a.3 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007018 - allele: - class: variation id: WBVar01499492 label: gk963546 - class: variation id: WBVar00442135 label: gk218892 - class: variation id: WBVar00961789 label: gk590043 - class: variation id: WBVar01498687 label: gk963948 - class: variation id: WBVar01499527 label: gk963590 - class: variation id: WBVar00961790 label: gk620192 - class: variation id: WBVar00961788 label: gk633454 - class: variation id: WBVar00442134 label: gk218891 - class: variation id: WBVar00961787 label: gk445152 - class: variation id: WBVar01499697 label: gk963795 - class: variation id: WBVar01499925 label: gk964078 - class: variation id: WBVar01498996 label: gk962765 - class: variation id: WBVar00442136 label: gk218893 - class: variation id: WBVar01500245 label: gk964500 - class: variation id: WBVar00094377 label: ok3353 - class: variation id: WBVar01499493 label: gk963547 - class: variation id: WBVar01500227 label: gk964476 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytosol. Predicted to be part of small ribosomal subunit. Is an ortholog of human RPS18 (ribosomal protein S18). label: rps-18 legacy_description: rps-18 encodes a small ribosomal subunit S18 protein. merged_into: ~ name: class: gene highlight: description_all: - rps-18 encodes a small ribosomal subunit S18 protein. id: WBGene00004487 label: rps-18 other_names: - Y57G11C.16 - CELE_Y57G11C.16 - CE14956 - Y57G11C.16.1 - Y57G11C.16 taxonomy: c_elegans other_names: - Y57G11C.16 - CELE_Y57G11C.16 - CE14956 - Y57G11C.16.1 - Y57G11C.16 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004487 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Cbn-mab-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00143374 label: Cbn-mab-5 other_names: - CBN04649 - CN29210 - CBN04649 - CBN04649.1 taxonomy: c_brenneri other_names: - CBN04649 - CN29210 - CBN04649 - CBN04649.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00143374 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: Cjp-mtp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00183332 label: Cjp-mtp-18 other_names: - CJA27759 - CJA27759 - CJA27759.1 - JA59271 taxonomy: c_japonica other_names: - CJA27759 - CJA27759 - CJA27759.1 - JA59271 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00183332 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: CJA08571 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00127775 label: CJA08571 other_names: - CJA08571 - CJA08571 - JA61499 - CJA08571.1 taxonomy: c_japonica other_names: - CJA08571 - CJA08571 - JA61499 - CJA08571.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00127775 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: Cre-mtp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00051551 label: Cre-mtp-18 other_names: - CRE00189 - cr01.sctg0.wum.546 - CRE00189.1 - CRE00189 - RP21811 taxonomy: c_remanei other_names: - CRE00189 - cr01.sctg0.wum.546 - CRE00189.1 - CRE00189 - RP21811 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00051551 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: Ovo-mtp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00239944 label: Ovo-mtp-18 other_names: - OVOC3135 - OVOC3135.2 - OVP09776 - OVOC3135.1 - OVOC3135 taxonomy: o_volvulus other_names: - OVOC3135 - OVOC3135.2 - OVP09776 - OVOC3135.1 - OVOC3135 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00239944 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: SRAE_1000036700 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00256963 label: SRAE_1000036700 other_names: - SRAE_1000036700 - SR01113 - SRAE_1000036700.1 - SRP07229 - SRAE_1000036700 taxonomy: s_ratti other_names: - SRAE_1000036700 - SR01113 - SRAE_1000036700.1 - SRP07229 - SRAE_1000036700 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00256963 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: Ppa-mtp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00116827 label: Ppa-mtp-18 other_names: - PPA27273 - UMM-S207-19.51 - GENEPREDICTION_SNAP300000084094 - PP57595 - PPA27273.1 - PPA27273 taxonomy: p_pacificus other_names: - PPA27273 - UMM-S207-19.51 - GENEPREDICTION_SNAP300000084094 - PP57595 - PPA27273.1 - PPA27273 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00116827 - allele: - class: variation id: WBVar01074504 label: gk900138 - class: variation id: WBVar00092526 label: ok1285 - class: variation id: WBVar01074519 label: gk398424 - class: variation id: WBVar00479296 label: gk256053 - class: variation id: WBVar00263047 label: ttTi37734 - class: variation id: WBVar01074515 label: gk431104 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01500160 label: gk964389 - class: variation id: WBVar01074508 label: gk853796 - class: variation id: WBVar00479295 label: gk256052 - class: variation id: WBVar01074517 label: gk884089 - class: variation id: WBVar01074498 label: gk677054 - class: variation id: WBVar01485109 label: gk949369 - class: variation id: WBVar01485108 label: gk949368 - class: variation id: WBVar00479293 label: gk256050 - class: variation id: WBVar01074522 label: gk560202 - class: variation id: WBVar01074507 label: gk444646 - class: variation id: WBVar01074496 label: gk764178 - class: variation id: WBVar01074499 label: gk378369 - class: variation id: WBVar01074489 label: gk887412 - class: variation id: WBVar01074518 label: gk324494 - class: variation id: WBVar01074495 label: gk874933 - class: variation id: WBVar01074497 label: gk681171 - class: variation id: WBVar01074502 label: gk476279 - class: variation id: WBVar00479298 label: gk256055 - class: variation id: WBVar01500212 label: gk964458 - class: variation id: WBVar01074500 label: gk506658 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar00479294 label: gk256051 - class: variation id: WBVar01074513 label: gk494253 - class: variation id: WBVar01074520 label: gk809302 - class: variation id: WBVar01074501 label: gk416391 - class: variation id: WBVar02150565 label: tm13098 - class: variation id: WBVar01074516 label: gk658630 - class: variation id: WBVar00479297 label: gk256054 - class: variation id: WBVar01074510 label: gk915919 - class: variation id: WBVar01074514 label: gk875373 - class: variation id: WBVar01074512 label: gk762906 - class: variation id: WBVar01074493 label: gk515643 - class: variation id: WBVar01074492 label: gk390361 - class: variation id: WBVar01074505 label: gk515644 - class: variation id: WBVar01500213 label: gk964459 - class: variation id: WBVar01074511 label: gk931152 - class: variation id: WBVar01074494 label: gk314084 - class: variation id: WBVar01074521 label: gk433990 - class: variation id: WBVar01074509 label: gk858854 - class: variation id: WBVar01074506 label: gk780130 - class: variation id: WBVar00479299 label: gk256056 - class: variation id: WBVar01074503 label: gk431389 - class: variation id: WBVar01074491 label: gk612634 - class: variation id: WBVar01074490 label: gk673061 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in excitatory postsynaptic potential and monoatomic ion transmembrane transport. Predicted to be located in neuron projection and synapse. Expressed in neurons and ray. label: acr-18 legacy_description: acr-18 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-18 falls into the 'DEG-3' class of nAChR subunits, apparently unique to nematodes, which includes DEG-3, DES-2, ACR-5, ACR-17, ACR-20, and ACR-23. merged_into: ~ name: class: gene highlight: description_all: - acr-18 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated - channel regulating fast action of acetylcholine at neuromuscular junctions and in the nervous system; ACR-18 id: WBGene00000057 label: acr-18 other_names: - F28F8.1 - CELE_F28F8.1 - F28F8.1 - CE36645 - F28F8.1.1 taxonomy: c_elegans other_names: - F28F8.1 - CELE_F28F8.1 - F28F8.1 - CE36645 - F28F8.1.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000057 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: CJA00992 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00120196 label: CJA00992 other_names: - CJA00992 - JA52436 - CJA00992a - CJA00992c - CJA00992a.1 - CJA00992b.1 - CJA00992b - JA55519 - CJA00992c.1 - JA66556 taxonomy: c_japonica other_names: - CJA00992 - JA52436 - CJA00992a - CJA00992c - CJA00992a.1 - CJA00992b.1 - CJA00992b - JA55519 - CJA00992c.1 - JA66556 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00120196 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: Cbn-mtp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00146962 label: Cbn-mtp-18 other_names: - CBN08237 - CBN08237.1 - CBN08237 - CN19838 taxonomy: c_brenneri other_names: - CBN08237 - CBN08237.1 - CBN08237 - CN19838 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00146962 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans R13H4.2 and tag-18. label: OVOC4754 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans R13H4.2 and tag-18. id: WBGene00241563 label: OVOC4754 other_names: - OVOC4754 - Ovo-tag-18 - OVP06445 - OVOC4754.1 - OVOC4754 taxonomy: o_volvulus other_names: - OVOC4754 - Ovo-tag-18 - OVP06445 - OVOC4754.1 - OVOC4754 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00241563 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: ASSOCIATED WITH developmental and epileptic encephalopathy 18; genetic disease; Obesity label: SZT2-AS1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - ASSOCIATED WITH developmental and epileptic encephalopathy 18; genetic disease; Obesity id: HGNC:41225 label: SZT2-AS1 other_names: - ~ - RGD:6481416 taxonomy: h_sapiens other_names: - ~ - RGD:6481416 page_type: gene species: key: h_sapiens name: Homo sapiens taxonomy: genus: Homo id: h_sapiens species: sapiens wbid: HGNC:41225 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans K10C9.7 and Y39A1A.18. label: CJA20649 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans K10C9.7 and Y39A1A.18. id: WBGene00176221 label: CJA20649 other_names: - CJA20649 - CJA20649.1 - CJA20649 - JA47414 taxonomy: c_japonica other_names: - CJA20649 - CJA20649.1 - CJA20649 - JA47414 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00176221 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Bma-mab-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00222332 label: Bma-mab-5 other_names: - Bm2071 - TAG11423 - Bm1_53740A - Bm-mab-5 - TAG9749 - Bm1_53740 - TAG2071 - Bm2071a.1 - BM39310 - Bm2071b - Bm2071b.1 - Bm2071a - BM47216 taxonomy: b_malayi other_names: - Bm2071 - TAG11423 - Bm1_53740A - Bm-mab-5 - TAG9749 - Bm1_53740 - TAG2071 - Bm2071a.1 - BM39310 - Bm2071b - Bm2071b.1 - Bm2071a - BM47216 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00222332 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Cjp-mab-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00136775 label: Cjp-mab-5 other_names: - CJA17572 - JA16886 - CJA17572b.1 - JA49318 - CJA17572a - CJA17572a.1 - CJA17572b taxonomy: c_japonica other_names: - CJA17572 - JA16886 - CJA17572b.1 - JA49318 - CJA17572a - CJA17572a.1 - CJA17572b page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00136775 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Cre-mab-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00064082 label: Cre-mab-5 other_names: - CRE26605 - cr01.sctg45.wum.18 - CRE26605.1 - CRE26605 - RP02961 taxonomy: c_remanei other_names: - CRE26605 - cr01.sctg45.wum.18 - CRE26605.1 - CRE26605 - RP02961 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00064082 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Ovo-mab-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00244672 label: Ovo-mab-5 other_names: - OVOC7863 - OVOC7863b.1 - OVOC7863b - OVOC7863a - OVP14632 - OVOC7863a.1 - OVP14596 taxonomy: o_volvulus other_names: - OVOC7863 - OVOC7863b.1 - OVOC7863b - OVOC7863a - OVP14632 - OVOC7863a.1 - OVP14596 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00244672 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II. label: Cbr-mab-5 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-5. - In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation id: WBGene00023539 label: Cbr-mab-5 other_names: - CBG00029 - CBG_00029 - CBG00029a - CBG00029a.1 - CBP00009 - CBG00029b - CBP42590 - CBG00029b.1 taxonomy: c_briggsae other_names: - CBG00029 - CBG_00029 - CBG00029a - CBG00029a.1 - CBP00009 - CBG00029b - CBP42590 - CBG00029b.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00023539 - allele: - class: variation id: WBVar00825409 label: gk903563 - class: variation id: WBVar01500247 label: gk964503 - class: variation id: WBVar01496097 label: gk960360 - class: variation id: WBVar00825408 label: gk330953 - class: variation id: WBVar00397175 label: gk173932 - class: variation id: WBVar00825407 label: gk422806 - class: variation id: WBVar01500248 label: gk964504 - class: variation id: WBVar01498455 label: gk963101 - class: variation id: WBVar00825410 label: gk347778 - class: variation id: WBVar01497518 label: gk961781 - class: variation id: WBVar01499068 label: gk962875 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in AIB and neurons based on tiling array; single-cell RNA-seq; and RNA-seq studies. Is affected by several genes including eat-2; daf-18; and csr-1 based on microarray and RNA-seq studies. Is affected by seven chemicals including methylmercuric chloride; Psoralens; and allantoin based on microarray and RNA-seq studies. label: C45G9.8 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including eat-2; daf-18; and csr-1 based on microarray and RNA-seq studies id: WBGene00016679 label: C45G9.8 other_names: - C45G9.8 - CELE_C45G9.8 - C45G9.8 - C45G9.8.3 - C45G9.8.1 - CE41619 - C45G9.8.2 taxonomy: c_elegans other_names: - C45G9.8 - CELE_C45G9.8 - C45G9.8 - C45G9.8.3 - C45G9.8.1 - CE41619 - C45G9.8.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00016679 - allele: - class: variation id: WBVar01197076 label: gk595405 - class: variation id: WBVar01197079 label: gk510978 - class: variation id: WBVar01499710 label: gk963810 - class: variation id: WBVar01197062 label: gk820826 - class: variation id: WBVar01197054 label: gk882782 - class: variation id: WBVar00599199 label: gk311425 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01197059 label: gk721882 - class: variation id: WBVar01197058 label: gk350045 - class: variation id: WBVar01197068 label: gk655995 - class: variation id: WBVar01499888 label: gk964029 - class: variation id: WBVar01197070 label: gk730558 - class: variation id: WBVar01197077 label: gk633092 - class: variation id: WBVar01499887 label: gk964028 - class: variation id: WBVar01197065 label: gk805917 - class: variation id: WBVar00520412 label: gk297169 - class: variation id: WBVar01197067 label: gk315579 - class: variation id: WBVar01498960 label: gk962707 - class: variation id: WBVar01197078 label: gk600305 - class: variation id: WBVar01197061 label: gk609059 - class: variation id: WBVar01197072 label: gk547821 - class: variation id: WBVar01197074 label: gk644021 - class: variation id: WBVar01197056 label: gk392094 - class: variation id: WBVar01197055 label: gk791162 - class: variation id: WBVar00520413 label: gk297170 - class: variation id: WBVar01197071 label: gk600304 - class: variation id: WBVar01197073 label: gk785791 - class: variation id: WBVar01197053 label: gk650759 - class: variation id: WBVar01197066 label: gk925162 - class: variation id: WBVar00520409 label: gk297166 - class: variation id: WBVar01197064 label: gk448977 - class: variation id: WBVar01197057 label: gk811275 - class: variation id: WBVar01197052 label: gk837313 - class: variation id: WBVar01492623 label: gk956886 - class: variation id: WBVar01197069 label: gk833188 - class: variation id: WBVar01494288 label: gk958551 - class: variation id: WBVar02152174 label: tm11874 - class: variation id: WBVar00520414 label: gk297171 - class: variation id: WBVar00520410 label: gk297167 - class: variation id: WBVar01197063 label: gk348714 - class: variation id: WBVar00599200 label: gk311426 - class: variation id: WBVar00520415 label: gk297172 - class: variation id: WBVar01197060 label: gk553647 - class: variation id: WBVar00520411 label: gk297168 - class: variation id: WBVar01197075 label: gk910998 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable glutamate-5-semialdehyde dehydrogenase activity. Predicted to be involved in L-proline biosynthetic process and phosphorylation. Located in mitochondrion. Human ortholog(s) of this gene implicated in several diseases, including cutis laxa (multiple); enterocele; and hereditary spastic paraplegia (multiple). Is an ortholog of human ALDH18A1 (aldehyde dehydrogenase 18 family member A1). label: alh-13 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human ALDH18A1 (aldehyde dehydrogenase 18 family member A1). id: WBGene00011938 label: alh-13 other_names: - T22H6.2 - CELE_T22H6.2 - CE47944 - T22H6.2a - T22H6.2a.1 - CE47964 - T22H6.2b.1 - T22H6.2b taxonomy: c_elegans other_names: - T22H6.2 - CELE_T22H6.2 - CE47944 - T22H6.2a - T22H6.2a.1 - CE47964 - T22H6.2b.1 - T22H6.2b page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00011938 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: Cbn-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00141635 label: Cbn-bus-18 other_names: - CBN02910 - Cbn-acl-10 - CBN02910 - CBN02910.1 - CN07701 - CBN02910 taxonomy: c_brenneri other_names: - CBN02910 - Cbn-acl-10 - CBN02910 - CBN02910.1 - CN07701 - CBN02910 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00141635 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans frpr-18. In C. elegans, frpr-18 is involved in G protein-coupled receptor signaling pathway; positive regulation of protein secretion; and sleep. label: CBN29232 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans frpr-18. - In C. elegans, frpr-18 is involved in G protein-coupled receptor signaling pathway; positive regulation id: WBGene00191197 label: CBN29232 other_names: - CBN29232 - CBN29232.1 - CN38033 - CBN29232 taxonomy: c_brenneri other_names: - CBN29232 - CBN29232.1 - CN38033 - CBN29232 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00191197 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: Cbr-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00041653 label: Cbr-bus-18 other_names: - CBG23269 - Cbr-acl-10 - CBG_23269 - CBG23269 - CBP12382 - CBG23269.1 taxonomy: c_briggsae other_names: - CBG23269 - Cbr-acl-10 - CBG_23269 - CBG23269 - CBP12382 - CBG23269.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00041653 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: Cre-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00052355 label: Cre-bus-18 other_names: - CRE27005 - Cre-acl-10 - cr01.sctg1.wum.233 - CRE27005.1 - CRE27005 - RP19572 taxonomy: c_remanei other_names: - CRE27005 - Cre-acl-10 - cr01.sctg1.wum.233 - CRE27005.1 - CRE27005 - RP19572 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00052355 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: Ovo-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00243112 label: Ovo-bus-18 other_names: - OVOC6303 - OVOC6303 - OVOC6303.2 - OVOC6303.1 - OVP03463 taxonomy: o_volvulus other_names: - OVOC6303 - OVOC6303 - OVOC6303.2 - OVOC6303.1 - OVP03463 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00243112 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: SRAE_0000037400 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00256118 label: SRAE_0000037400 other_names: - SRAE_0000037400 - SRP05213 - SRAE_0000037400.1 - SRAE_0000037400 taxonomy: s_ratti other_names: - SRAE_0000037400 - SRP05213 - SRAE_0000037400.1 - SRAE_0000037400 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00256118 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: Ppa-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00118334 label: Ppa-bus-18 other_names: - PPA28780 - Ppa-acl-10 - GENEPREDICTION_SNAP300000085572 - UMM-S259-13.14 - PP60181 - PPA28780.1 - PPA28780 taxonomy: p_pacificus other_names: - PPA28780 - Ppa-acl-10 - GENEPREDICTION_SNAP300000085572 - UMM-S259-13.14 - PP60181 - PPA28780.1 - PPA28780 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00118334 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Orthologous to human MAB21L3 (mab-21 like 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,3',4,4',5-pentachlorobiphenyl. label: Mab21l3 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Orthologous to human MAB21L3 (mab-21 like 3); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine id: RGD:1308694 label: Mab21l3 other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:1308694 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans irld-18 and irld-4. label: CRE02742 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans irld-18 and irld-4. id: WBGene00069729 label: CRE02742 other_names: - CRE02742 - cr01.sctg158.wum.22 - RP27237 - CRE02742 - CRE02742.1 taxonomy: c_remanei other_names: - CRE02742 - cr01.sctg158.wum.22 - RP27237 - CRE02742 - CRE02742.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00069729 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. label: CRE09893 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. id: WBGene00085089 label: CRE09893 other_names: - CRE09893 - CRE09893 - CRE09893.1 - RP38851 taxonomy: c_remanei other_names: - CRE09893 - CRE09893 - CRE09893.1 - RP38851 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00085089 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. label: CRE20563 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. id: WBGene00081446 label: CRE20563 other_names: - CRE20563 - RP45891 - CRE20563 - CRE20563.1 taxonomy: c_remanei other_names: - CRE20563 - RP45891 - CRE20563 - CRE20563.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00081446 - allele: - class: variation id: WBVar00670361 label: gk758425 - class: variation id: WBVar00670358 label: gk341384 - class: variation id: WBVar00670354 label: gk665369 - class: variation id: WBVar00670359 label: gk437633 - class: variation id: WBVar00670352 label: gk380578 - class: variation id: WBVar00345202 label: gk121959 - class: variation id: WBVar00670347 label: gk782110 - class: variation id: WBVar00670360 label: gk695193 - class: variation id: WBVar00670365 label: gk688362 - class: variation id: WBVar00670357 label: gk690272 - class: variation id: WBVar00670355 label: gk749377 - class: variation id: WBVar00670363 label: gk908971 - class: variation id: WBVar00670351 label: gk717670 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar01499054 label: gk962858 - class: variation id: WBVar01499788 label: gk963906 - class: variation id: WBVar00670364 label: gk606162 - class: variation id: WBVar00264123 label: ttTi41511 - class: variation id: WBVar00345203 label: gk121960 - class: variation id: WBVar00670362 label: gk723256 - class: variation id: WBVar00345200 label: gk121957 - class: variation id: WBVar00670348 label: gk757888 - class: variation id: WBVar00670353 label: gk608397 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00670356 label: gk481361 - class: variation id: WBVar00345201 label: gk121958 - class: variation id: WBVar00670350 label: gk862399 - class: variation id: WBVar00670349 label: gk445031 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in ABplpppppp; ABprpppppp; AVG; RIM; and command interneuron based on RNA-seq and single-cell RNA-seq studies. Is affected by several genes including daf-16; hsf-1; and daf-18 based on RNA-seq and microarray studies. Is affected by four chemicals including Psoralens; allantoin; and Sirolimus based on RNA-seq studies. label: Y52B11A.11 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; hsf-1; and daf-18 based on RNA-seq and microarray studies id: WBGene00014914 label: Y52B11A.11 other_names: - Y52B11A.11 - CELE_Y52B11A.11 - Y52B11A.11 - CE50503 - Y52B11A.11.1 taxonomy: c_elegans other_names: - Y52B11A.11 - CELE_Y52B11A.11 - Y52B11A.11 - CE50503 - Y52B11A.11.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00014914 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans klp-10 and klp-18. label: CJA10630 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-10 and klp-18. id: WBGene00129834 label: CJA10630 other_names: - CJA10630 - JA42232 - CJA10630b - JA54925 - CJA10630a - CJA10630a.1 - CJA10630b.1 taxonomy: c_japonica other_names: - CJA10630 - JA42232 - CJA10630b - JA54925 - CJA10630a - CJA10630a.1 - CJA10630b.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00129834 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans irld-18 and irld-4. label: CRE03485 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans irld-18 and irld-4. id: WBGene00074378 label: CRE03485 other_names: - CRE03485 - cr01.sctg1279.wum.1 - CRE03485.1 - RP49592 - CRE03485 taxonomy: c_remanei other_names: - CRE03485 - cr01.sctg1279.wum.1 - CRE03485.1 - RP49592 - CRE03485 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00074378 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans bus-18. In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic process. label: Cjp-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans bus-18. - In C. elegans, bus-18 is involved in morphogenesis of an epithelium and phosphatidylinositol metabolic id: WBGene00136823 label: Cjp-bus-18 other_names: - CJA17618 - Cjp-acl-10 - CJA17618.1 - JA57541 - CJA17618 taxonomy: c_japonica other_names: - CJA17618 - Cjp-acl-10 - CJA17618.1 - JA57541 - CJA17618 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00136823 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans irld-18 and irld-4. label: CBN02011 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans irld-18 and irld-4. id: WBGene00140736 label: CBN02011 other_names: - CBN02011 - CBN02011.1 - CBN02011 - CN15995 taxonomy: c_brenneri other_names: - CBN02011 - CBN02011.1 - CBN02011 - CN15995 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00140736 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. label: CRE20555 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. id: WBGene00081449 label: CRE20555 other_names: - CRE20555 - CRE20555 - CRE20555.1 - RP38698 taxonomy: c_remanei other_names: - CRE20555 - CRE20555 - CRE20555.1 - RP38698 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00081449 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. label: CRE20564 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. id: WBGene00081448 label: CRE20564 other_names: - CRE20564 - RP40427 - CRE20564.1 - CRE20564 taxonomy: c_remanei other_names: - CRE20564 - RP40427 - CRE20564.1 - CRE20564 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00081448 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans C18H2.5; F37A4.4; and lido-18. label: CJA31049 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans C18H2.5; F37A4.4; and lido-18. id: WBGene00206896 label: CJA31049 other_names: - CJA31049 - JA60297 - CJA31049.1 - CJA31049 taxonomy: c_japonica other_names: - CJA31049 - JA60297 - CJA31049.1 - CJA31049 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00206896 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. label: CRE20554 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. id: WBGene00071247 label: CRE20554 other_names: - CRE20554 - cr01.sctg236.wum.7 - CRE20554.1 - CRE20554 - RP24080 taxonomy: c_remanei other_names: - CRE20554 - cr01.sctg236.wum.7 - CRE20554.1 - CRE20554 - RP24080 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00071247 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. label: CRE20556 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y105C5B.17 and Y105C5B.18. id: WBGene00071246 label: CRE20556 other_names: - CRE20556 - cr01.sctg236.wum.6 - CRE20556 - RP33030 - CRE20556.1 taxonomy: c_remanei other_names: - CRE20556 - cr01.sctg236.wum.6 - CRE20556 - RP33030 - CRE20556.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00071246 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Calycin. Is an ortholog of C. elegans mab-7." label: SRAE_X000004200 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-7. id: WBGene00265596 label: SRAE_X000004200 other_names: - SRAE_X000004200 - SR00246 - SRAE_X000004200 - SRAE_X000004200.1 - SRP06471 taxonomy: s_ratti other_names: - SRAE_X000004200 - SR00246 - SRAE_X000004200 - SRAE_X000004200.1 - SRP06471 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00265596 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans irld-18 and irld-4. label: CRE17520 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans irld-18 and irld-4. id: WBGene00080550 label: CRE17520 other_names: - CRE17520 - CRE17520.1 - CRE17520 - RP32271 taxonomy: c_remanei other_names: - CRE17520 - CRE17520.1 - CRE17520 - RP32271 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00080550 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans irld-18 and irld-4. label: CRE24336 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans irld-18 and irld-4. id: WBGene00069725 label: CRE24336 other_names: - CRE24336 - cr01.sctg158.wum.18 - RP34348 - CRE24336.1 - CRE24336 taxonomy: c_remanei other_names: - CRE24336 - cr01.sctg158.wum.18 - RP34348 - CRE24336.1 - CRE24336 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00069725 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans mab-23. In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. label: Ppa-mab-23 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-23. - In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination id: WBGene00276128 label: Ppa-mab-23 other_names: - PPA37759 - PPA37759 - PP66249 - PPA37759.1 taxonomy: p_pacificus other_names: - PPA37759 - PPA37759 - PP66249 - PPA37759.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00276128 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Calycin. Is an ortholog of C. elegans mab-7." label: Cjp-mab-7 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-7. id: WBGene00134474 label: Cjp-mab-7 other_names: - CJA15270 - CJA15270a.1 - CJA15270b - JA30014 - CJA15270b.1 - CJA15270a - JA45391 taxonomy: c_japonica other_names: - CJA15270 - CJA15270a.1 - CJA15270b - JA30014 - CJA15270b.1 - CJA15270a - JA45391 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00134474 - allele: - class: variation id: WBVar00422372 label: gk199129 - class: variation id: WBVar01499144 label: gk962995 - class: variation id: WBVar01499128 label: gk962973 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00299991 label: otn3170 - class: variation id: WBVar01499790 label: gk963908 - class: variation id: WBVar01499127 label: gk962972 - class: variation id: WBVar00901890 label: gk428825 - class: variation id: WBVar00901889 label: gk462380 - class: variation id: WBVar00901892 label: gk686231 - class: variation id: WBVar00901894 label: gk322315 - class: variation id: WBVar00901893 label: gk573333 - class: variation id: WBVar01481713 label: gk945972 - class: variation id: WBVar01499143 label: gk962994 - class: variation id: WBVar00901896 label: gk377740 - class: variation id: WBVar00422371 label: gk199128 - class: variation id: WBVar00901888 label: gk854911 - class: variation id: WBVar00901884 label: gk482560 - class: variation id: WBVar00901891 label: gk618397 - class: variation id: WBVar00901885 label: gk793015 - class: variation id: WBVar00901895 label: gk852162 - class: variation id: WBVar00901887 label: gk920855 - class: variation id: WBVar00297416 label: otn595 - class: variation id: WBVar00901886 label: gk439044 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by several genes including daf-16; skn-1; and daf-18 based on RNA-seq and microarray studies. Is affected by nitroguanidine based on microarray studies. Is predicted to encode a protein with the following domains: C-type lectin fold; Lectin C-type domain; C-type lectin-like/link domain superfamily; and C-type lectin-like." label: Y46C8AM.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-16; skn-1; and daf-18 based on RNA-seq and microarray studies id: WBGene00271795 label: Y46C8AM.1 other_names: - Y46C8AM.1 - CELE_Y46C8AM.1 - CE33872 - Y46C8AM.1.1 - Y46C8AM.1.2 - Y46C8AM.1 - Y46C8AM.1.3 taxonomy: c_elegans other_names: - Y46C8AM.1 - CELE_Y46C8AM.1 - CE33872 - Y46C8AM.1.1 - Y46C8AM.1.2 - Y46C8AM.1 - Y46C8AM.1.3 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00271795 - allele: - class: variation id: WBVar01496277 label: gk960540 - class: variation id: WBVar00875784 label: gk778638 - class: variation id: WBVar02151879 label: tm11554 - class: variation id: WBVar00875779 label: gk756770 - class: variation id: WBVar00875760 label: gk777107 - class: variation id: WBVar00413774 label: gk190531 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar00413783 label: gk190540 - class: variation id: WBVar00249648 label: tm613 - class: variation id: WBVar00413782 label: gk190539 - class: variation id: WBVar00875777 label: gk671250 - class: variation id: WBVar00875790 label: gk381502 - class: variation id: WBVar00875755 label: gk859147 - class: variation id: WBVar00875753 label: gk595628 - class: variation id: WBVar00413778 label: gk190535 - class: variation id: WBVar00875765 label: gk601996 - class: variation id: WBVar00413784 label: gk190541 - class: variation id: WBVar00413771 label: gk190528 - class: variation id: WBVar00875758 label: gk743531 - class: variation id: WBVar00875783 label: gk611677 - class: variation id: WBVar00413773 label: gk190530 - class: variation id: WBVar00875754 label: gk512294 - class: variation id: WBVar02133067 label: h11244 - class: variation id: WBVar00875756 label: gk473678 - class: variation id: WBVar00413775 label: gk190532 - class: variation id: WBVar01492903 label: gk957166 - class: variation id: WBVar00875748 label: gk541161 - class: variation id: WBVar00875751 label: gk385117 - class: variation id: WBVar00875749 label: gk547480 - class: variation id: WBVar00875767 label: gk679106 - class: variation id: WBVar00875778 label: gk836414 - class: variation id: WBVar00413780 label: gk190537 - class: variation id: WBVar00875763 label: gk675262 - class: variation id: WBVar00875768 label: gk610341 - class: variation id: WBVar00413777 label: gk190534 - class: variation id: WBVar00875773 label: gk420519 - class: variation id: WBVar00094596 label: ok3642 - class: variation id: WBVar00875776 label: gk880525 - class: variation id: WBVar00277367 label: gk1888 - class: variation id: WBVar00875782 label: gk924861 - class: variation id: WBVar00875792 label: gk767577 - class: variation id: WBVar00875775 label: gk559200 - class: variation id: WBVar01498679 label: gk963904 - class: variation id: WBVar00875752 label: gk458655 - class: variation id: WBVar00875781 label: gk613081 - class: variation id: WBVar00413785 label: gk190542 - class: variation id: WBVar00875785 label: gk801454 - class: variation id: WBVar01498619 label: gk963552 - class: variation id: WBVar00875764 label: gk440510 - class: variation id: WBVar00413776 label: gk190533 - class: variation id: WBVar00875757 label: gk504252 - class: variation id: WBVar00875769 label: gk859540 - class: variation id: WBVar00413781 label: gk190538 - class: variation id: WBVar00875786 label: gk442956 - class: variation id: WBVar00413779 label: gk190536 - class: variation id: WBVar01480969 label: gk945228 - class: variation id: WBVar00875759 label: gk524000 - class: variation id: WBVar00875791 label: gk625262 - class: variation id: WBVar00146373 label: gm336 - class: variation id: WBVar00875770 label: gk672478 - class: variation id: WBVar00875771 label: gk762835 - class: variation id: WBVar00875789 label: gk894049 - class: variation id: WBVar00091910 label: ok626 - class: variation id: WBVar00875766 label: gk797613 - class: variation id: WBVar00875774 label: gk429378 - class: variation id: WBVar00875788 label: gk733017 - class: variation id: WBVar00875772 label: gk570449 - class: variation id: WBVar00875787 label: gk581322 - class: variation id: WBVar00413772 label: gk190529 - class: variation id: WBVar01499629 label: gk963715 - class: variation id: WBVar00875750 label: gk533388 - class: variation id: WBVar00875762 label: gk605665 - class: variation id: WBVar00875780 label: gk852488 - class: variation id: WBVar00875761 label: gk658485 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Expressed in head and tail. Is predicted to encode a protein with the following domains: BTB/POZ domain; BTB-kelch protein; BTB And C-terminal Kelch; Kelch-type beta propeller; Kelch motif; BTB/Kelch-associated; SKP1/BTB/POZ domain superfamily; and Kelch repeat type 1. Is an ortholog of human KLHL18 (kelch like family member 18)." label: kel-3 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human KLHL18 (kelch like family member 18). id: WBGene00002185 label: kel-3 other_names: - T27E9.4 - yk103a10 - CELE_T27E9.4 - T27E9.4a.1 - T27E9.4b.1 - T27E9.4b - CE29825 - T27E9.4b.2 - CE29824 - T27E9.4a - T27E9.4a.2 taxonomy: c_elegans other_names: - T27E9.4 - yk103a10 - CELE_T27E9.4 - T27E9.4a.1 - T27E9.4b.1 - T27E9.4b - CE29825 - T27E9.4b.2 - CE29824 - T27E9.4a - T27E9.4a.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00002185 - allele: - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00740043 label: gk663798 - class: variation id: WBVar00740042 label: gk794582 - class: variation id: WBVar00368818 label: gk145575 - class: variation id: WBVar01497345 label: gk961608 - class: variation id: WBVar00317921 label: snx349 - class: variation id: WBVar00740039 label: gk670281 - class: variation id: WBVar00740044 label: gk391921 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar01477577 label: gk941835 - class: variation id: WBVar00740038 label: gk441341 - class: variation id: WBVar00740041 label: gk902504 - class: variation id: WBVar00740037 label: gk441340 - class: variation id: WBVar00740040 label: gk325138 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by several genes including daf-2; daf-18; and isp-1 based on tiling array; microarray; and RNA-seq studies. Is affected by eight chemicals including resveratrol; Hydrolyzable Tannins; and Humic Substances based on microarray studies. Is predicted to encode a protein with the following domains: CC domain; ShK domain-like; and ShKT domain." label: F41G3.20 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-2; daf-18; and isp-1 based on tiling array; microarray; and id: WBGene00044315 label: F41G3.20 other_names: - F41G3.20 - CELE_F41G3.20 - F41G3.20.1 - F41G3.20 - CE47953 taxonomy: c_elegans other_names: - F41G3.20 - CELE_F41G3.20 - F41G3.20.1 - F41G3.20 - CE47953 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00044315 - allele: - class: variation id: WBVar00864815 label: gk770535 - class: variation id: WBVar01497711 label: gk961974 - class: variation id: WBVar00410171 label: gk186928 - class: variation id: WBVar00864787 label: gk561843 - class: variation id: WBVar00864817 label: gk848363 - class: variation id: WBVar00864785 label: gk390229 - class: variation id: WBVar00864818 label: gk723533 - class: variation id: WBVar00410173 label: gk186930 - class: variation id: WBVar00864824 label: gk334210 - class: variation id: WBVar00864807 label: gk690009 - class: variation id: WBVar01500139 label: gk964364 - class: variation id: WBVar00864781 label: gk765291 - class: variation id: WBVar00864797 label: gk907954 - class: variation id: WBVar00864790 label: gk387413 - class: variation id: WBVar00864810 label: gk789022 - class: variation id: WBVar00864793 label: gk871939 - class: variation id: WBVar00410167 label: gk186924 - class: variation id: WBVar00864803 label: gk807044 - class: variation id: WBVar00864788 label: gk667716 - class: variation id: WBVar00864796 label: gk747476 - class: variation id: WBVar00864791 label: gk760078 - class: variation id: WBVar00864804 label: gk914671 - class: variation id: WBVar01499701 label: gk963799 - class: variation id: WBVar00864812 label: gk867342 - class: variation id: WBVar00864802 label: gk915140 - class: variation id: WBVar00864795 label: gk507007 - class: variation id: WBVar00864789 label: gk861597 - class: variation id: WBVar00864811 label: gk811611 - class: variation id: WBVar00410176 label: gk186933 - class: variation id: WBVar01500138 label: gk964363 - class: variation id: WBVar00410178 label: gk186935 - class: variation id: WBVar00864792 label: gk335129 - class: variation id: WBVar00864813 label: gk829442 - class: variation id: WBVar00864809 label: gk745392 - class: variation id: WBVar00864801 label: gk580664 - class: variation id: WBVar00864821 label: gk426291 - class: variation id: WBVar00864783 label: gk705975 - class: variation id: WBVar00410172 label: gk186929 - class: variation id: WBVar00410177 label: gk186934 - class: variation id: WBVar00864819 label: gk346132 - class: variation id: WBVar00264317 label: ttTi42097 - class: variation id: WBVar00864823 label: gk654841 - class: variation id: WBVar00864816 label: gk762024 - class: variation id: WBVar00864780 label: gk488723 - class: variation id: WBVar00410169 label: gk186926 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar01497723 label: gk961986 - class: variation id: WBVar00410170 label: gk186927 - class: variation id: WBVar00864808 label: gk846618 - class: variation id: WBVar00864798 label: gk617826 - class: variation id: WBVar00864822 label: gk812957 - class: variation id: WBVar00410175 label: gk186932 - class: variation id: WBVar00864782 label: gk821684 - class: variation id: WBVar01499239 label: gk963147 - class: variation id: WBVar00864805 label: gk771922 - class: variation id: WBVar00864784 label: gk489186 - class: variation id: WBVar00864800 label: gk923086 - class: variation id: WBVar00410168 label: gk186925 - class: variation id: WBVar00410174 label: gk186931 - class: variation id: WBVar01497742 label: gk962005 - class: variation id: WBVar00864794 label: gk556242 - class: variation id: WBVar00309970 label: otn13149 - class: variation id: WBVar00864814 label: gk797021 - class: variation id: WBVar00864786 label: gk351081 - class: variation id: WBVar00410165 label: gk186922 - class: variation id: WBVar00410166 label: gk186923 - class: variation id: WBVar00864806 label: gk617260 - class: variation id: WBVar00864820 label: gk872512 - class: variation id: WBVar00864799 label: gk400120 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in migraine. Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18). label: twk-39 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18). id: WBGene00006690 label: twk-39 other_names: - C24H11.8 - CELE_C24H11.8 - CE40599 - CE31773 - C24H11.8b.1 - C24H11.8a - C24H11.8b - C24H11.8a.1 taxonomy: c_elegans other_names: - C24H11.8 - CELE_C24H11.8 - CE40599 - CE31773 - C24H11.8b.1 - C24H11.8a - C24H11.8b - C24H11.8a.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006690 - allele: - class: variation id: WBVar00852950 label: gk927602 - class: variation id: WBVar00852952 label: gk474666 - class: variation id: WBVar00406178 label: gk182935 - class: variation id: WBVar00852951 label: gk399721 - class: variation id: WBVar01500260 label: gk964518 - class: variation id: WBVar00852948 label: gk636196 - class: variation id: WBVar00852957 label: gk359013 - class: variation id: WBVar01488772 label: gk953035 - class: variation id: WBVar00852959 label: gk385104 - class: variation id: WBVar00852949 label: gk543140 - class: variation id: WBVar01489766 label: gk954029 - class: variation id: WBVar00852958 label: gk887202 - class: variation id: WBVar00852953 label: gk367522 - class: variation id: WBVar00852955 label: gk919144 - class: variation id: WBVar00314806 label: otn17985 - class: variation id: WBVar01499774 label: gk963887 - class: variation id: WBVar00852954 label: gk867986 - class: variation id: WBVar00852960 label: gk456725 - class: variation id: WBVar00406179 label: gk182936 - class: variation id: WBVar02146227 label: tm8248 - class: variation id: WBVar00406180 label: gk182937 - class: variation id: WBVar00852956 label: gk474667 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion transmembrane transport and stabilization of membrane potential. Predicted to be located in membrane. Human ortholog(s) of this gene implicated in migraine. Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18). label: twk-48 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human KCNK18 (potassium two pore domain channel subfamily K member 18). id: WBGene00010784 label: twk-48 other_names: - K11H3.7 - CELE_K11H3.7 - K11H3.7.1 - CE34935 - K11H3.7 taxonomy: c_elegans other_names: - K11H3.7 - CELE_K11H3.7 - K11H3.7.1 - CE34935 - K11H3.7 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00010784 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Saposin-like. Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response." label: Ppa-spp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response. id: WBGene00114075 label: Ppa-spp-18 other_names: - PPA24521 - UMM-S196-16.27 - GENEPREDICTION_SNAP300000081405 - PPA24521 - PP64532 - PPA24521.2 - PPA24521.1 taxonomy: p_pacificus other_names: - PPA24521 - UMM-S196-16.27 - GENEPREDICTION_SNAP300000081405 - PPA24521 - PP64532 - PPA24521.2 - PPA24521.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00114075 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Is an ortholog of C. elegans mab-23. In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. label: OVOC6127 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-23. - In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination id: WBGene00242936 label: OVOC6127 other_names: - OVOC6127 - OVOC6127 - OVOC6127.1 - OVP14202 taxonomy: o_volvulus other_names: - OVOC6127 - OVOC6127 - OVOC6127.1 - OVP14202 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00242936 - allele: - class: variation id: WBVar00415260 label: gk192017 - class: variation id: WBVar00880311 label: gk410961 - class: variation id: WBVar00415261 label: gk192018 - class: variation id: WBVar00880301 label: gk874090 - class: variation id: WBVar00880300 label: gk922326 - class: variation id: WBVar00143952 label: e1375 - class: variation id: WBVar00880293 label: gk899481 - class: variation id: WBVar01499166 label: gk963025 - class: variation id: WBVar02150062 label: sy881 - class: variation id: WBVar00880288 label: gk324074 - class: variation id: WBVar00880294 label: gk734242 - class: variation id: WBVar01499328 label: gk963324 - class: variation id: WBVar00091389 label: nr2037 - class: variation id: WBVar00880286 label: gk758637 - class: variation id: WBVar00880278 label: gk508533 - class: variation id: WBVar00415258 label: gk192015 - class: variation id: WBVar00415262 label: gk192019 - class: variation id: WBVar01499385 label: gk963403 - class: variation id: WBVar00880281 label: gk835711 - class: variation id: WBVar02125757 label: pe407 - class: variation id: WBVar00880277 label: gk530207 - class: variation id: WBVar00880284 label: gk367186 - class: variation id: WBVar00255104 label: ttTi6481 - class: variation id: WBVar01499329 label: gk963325 - class: variation id: WBVar01499608 label: gk963690 - class: variation id: WBVar00880292 label: gk568361 - class: variation id: WBVar00880306 label: gk921369 - class: variation id: WBVar02125489 label: tm5119 - class: variation id: WBVar00880296 label: gk444129 - class: variation id: WBVar00415256 label: gk192013 - class: variation id: WBVar01499499 label: gk963558 - class: variation id: WBVar00880309 label: gk602875 - class: variation id: WBVar00880299 label: gk747500 - class: variation id: WBVar00880310 label: gk593863 - class: variation id: WBVar00880312 label: gk896730 - class: variation id: WBVar00415257 label: gk192014 - class: variation id: WBVar00257522 label: ttTi14584 - class: variation id: WBVar01481042 label: gk945301 - class: variation id: WBVar00880275 label: gk572813 - class: variation id: WBVar00880297 label: gk347095 - class: variation id: WBVar01499633 label: gk963722 - class: variation id: WBVar00880276 label: gk931596 - class: variation id: WBVar00880313 label: gk804286 - class: variation id: WBVar00089257 label: mu398 - class: variation id: WBVar00880305 label: gk702867 - class: variation id: WBVar00880298 label: gk321834 - class: variation id: WBVar02125758 label: pe408 - class: variation id: WBVar00880283 label: gk427280 - class: variation id: WBVar00880308 label: gk514590 - class: variation id: WBVar00880295 label: gk764496 - class: variation id: WBVar00880290 label: gk474205 - class: variation id: WBVar02150064 label: sy882 - class: variation id: WBVar02133178 label: h3379 - class: variation id: WBVar00088917 label: mg198 - class: variation id: WBVar00880282 label: gk428226 - class: variation id: WBVar00880289 label: gk933121 - class: variation id: WBVar01499498 label: gk963557 - class: variation id: WBVar00880303 label: gk865450 - class: variation id: WBVar00880285 label: gk825838 - class: variation id: WBVar00880304 label: gk647182 - class: variation id: WBVar00091768 label: ok480 - class: variation id: WBVar00880279 label: gk452207 - class: variation id: WBVar00880280 label: gk590523 - class: variation id: WBVar01499384 label: gk963402 - class: variation id: WBVar00880302 label: gk919172 - class: variation id: WBVar00880291 label: gk921368 - class: variation id: WBVar02150060 label: sy879 - class: variation id: WBVar02150061 label: sy887 - class: variation id: WBVar00880307 label: gk904509 - class: variation id: WBVar02150063 label: sy885 - class: variation id: WBVar00089256 label: mu397 - class: variation id: WBVar02125490 label: tm5288 - class: variation id: WBVar00880287 label: gk804733 - class: variation id: WBVar02133179 label: h16666 - class: variation id: WBVar00415259 label: gk192016 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables protein tyrosine phosphatase activity. Involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. Acts upstream of with a positive effect on protein import into nucleus. Located in several cellular components, including axon; cytoplasmic side of plasma membrane; and somatodendritic compartment. Expressed in several structures, including Z2; egg-laying apparatus; germ line; oocyte; and somatic nervous system. Used to study cancer. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); gastrointestinal system cancer (multiple); and nervous system cancer (multiple). Is an ortholog of human PTEN (phosphatase and tensin homolog). label: daf-18 legacy_description: daf-18 encodes a lipid phosphatase homologous to the human PTEN tumor suppresor (OMIM:601728, mutated in Cowden disease and several cancers); DAF-18 negatively regulates insulin-like signaling mediated by DAF-2/IR and AGE-1/PI3K and thus plays a role in metabolism, development, and longevity; based on sequence and genetic analysis, DAF-18 is predicted to dephosphorylate AGE-1-generated PIP3 in order to limit activation of the downstream AKT-1 and AKT-2 kinases that negatively regulate DAF-16. merged_into: ~ name: class: gene highlight: description_all: - daf-18 encodes a lipid phosphatase homologous to the human PTEN tumor suppresor (OMIM:601728, mutated - in Cowden disease and several cancers); DAF-18 negatively regulates insulin-like signaling mediated - plays a role in metabolism, development, and longevity; based on sequence and genetic analysis, DAF-18 id: WBGene00000913 label: daf-18 other_names: - T07A9.6 - CELE_T07A9.6 - CE26385 - T07A9.6 - T07A9.6.1 taxonomy: c_elegans other_names: - T07A9.6 - CELE_T07A9.6 - CE26385 - T07A9.6 - T07A9.6.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000913 - allele: - class: variation id: WBVar00504398 label: gk281155 - class: variation id: WBVar01149324 label: gk700417 - class: variation id: WBVar00091416 label: nu90 - class: variation id: WBVar01149339 label: gk837832 - class: variation id: WBVar00504394 label: gk281151 - class: variation id: WBVar01149316 label: gk791476 - class: variation id: WBVar01149332 label: gk811926 - class: variation id: WBVar01149321 label: gk319736 - class: variation id: WBVar01149340 label: gk673109 - class: variation id: WBVar01149336 label: gk720989 - class: variation id: WBVar00089715 label: n733 - class: variation id: WBVar01149312 label: gk774233 - class: variation id: WBVar00504393 label: gk281150 - class: variation id: WBVar00504396 label: gk281153 - class: variation id: WBVar01149325 label: gk883103 - class: variation id: WBVar00504397 label: gk281154 - class: variation id: WBVar01149334 label: gk771260 - class: variation id: WBVar01149327 label: gk636595 - class: variation id: WBVar01149310 label: gk752795 - class: variation id: WBVar01149337 label: gk481250 - class: variation id: WBVar00254701 label: ttTi4929 - class: variation id: WBVar01149328 label: gk493363 - class: variation id: WBVar00091705 label: ok411 - class: variation id: WBVar00504401 label: gk281158 - class: variation id: WBVar01149342 label: gk661983 - class: variation id: WBVar01149319 label: gk414991 - class: variation id: WBVar01149323 label: gk628511 - class: variation id: WBVar01149333 label: gk773083 - class: variation id: WBVar01149320 label: gk771259 - class: variation id: WBVar01149335 label: gk597974 - class: variation id: WBVar01149306 label: gk900232 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01149322 label: gk505103 - class: variation id: WBVar00504399 label: gk281156 - class: variation id: WBVar01149329 label: gk888384 - class: variation id: WBVar00504395 label: gk281152 - class: variation id: WBVar01149309 label: gk848089 - class: variation id: WBVar00143752 label: e1111 - class: variation id: WBVar01149326 label: gk611323 - class: variation id: WBVar01149307 label: gk613362 - class: variation id: WBVar01149338 label: gk526154 - class: variation id: WBVar02139338 label: h15305 - class: variation id: WBVar00504391 label: gk281148 - class: variation id: WBVar01149311 label: gk420127 - class: variation id: WBVar00504400 label: gk281157 - class: variation id: WBVar01149331 label: gk755692 - class: variation id: WBVar01149315 label: gk450721 - class: variation id: WBVar01149318 label: gk698963 - class: variation id: WBVar01149330 label: gk372276 - class: variation id: WBVar01149308 label: gk803431 - class: variation id: WBVar00504402 label: gk281159 - class: variation id: WBVar01149313 label: gk845159 - class: variation id: WBVar01149314 label: gk828080 - class: variation id: WBVar01149317 label: gk335729 - class: variation id: WBVar01149341 label: gk553566 - class: variation id: WBVar00504392 label: gk281149 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables dopamine:sodium symporter activity and serotonin:sodium:chloride symporter activity. Involved in dopamine metabolic process; feeding behavior; and monoamine transport. Located in synaptic vesicle. Expressed in gonad; nervous system; and in male. Used to study amphetamine abuse and cocaine abuse. Human ortholog(s) of this gene implicated in several diseases, including bipolar disorder; type 1 diabetes mellitus; and von Hippel-Lindau disease. Is an ortholog of human SLC18A1 (solute carrier family 18 member A1) and SLC18A2 (solute carrier family 18 member A2). label: cat-1 legacy_description: cat-1 encodes a synaptic vesicular monoamine transporter required for the presence of dopamine and serotonin in nerve terminals, for the normal slowing of worms on a bacterial lawn (versus clean agar), for faster pharyngeal pumping on food, and for a normally (high) rate of egg-laying. merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human SLC18A1 (solute carrier family 18 member A1) and SLC18A2 (solute carrier family - 18 member A2). id: WBGene00000295 label: cat-1 other_names: - W01C8.6 - CELE_W01C8.6 - W01C8.6 - CE35792 - W01C8.6.1 - W01C8.6.2 taxonomy: c_elegans other_names: - W01C8.6 - CELE_W01C8.6 - W01C8.6 - CE35792 - W01C8.6.1 - W01C8.6.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00000295 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans F36H9.5; nspc-20; and nspc-18. label: CJA15246 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans F36H9.5; nspc-20; and nspc-18. id: WBGene00134450 label: CJA15246 other_names: - CJA15246 - CJA15246.1 - JA49479 - CJA15246 taxonomy: c_japonica other_names: - CJA15246 - CJA15246.1 - JA49479 - CJA15246 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00134450 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Syntaxin 18 (Syx18) encodes a SNAP receptor involved in neuromuscular synaptic transmission. label: Syx18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Syntaxin 18 (Syx18) encodes a SNAP receptor involved in neuromuscular synaptic transmission. id: FB:FBgn0039212 label: Syx18 other_names: - ~ - FB:CG13626 taxonomy: d_melanogaster other_names: - ~ - FB:CG13626 page_type: gene species: key: d_melanogaster name: Drosophila melanogaster taxonomy: genus: Drosophila id: d_melanogaster species: melanogaster wbid: FB:FBgn0039212 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Saposin B type domain. Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response." label: Cbn-spp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response. id: WBGene00140260 label: Cbn-spp-18 other_names: - CBN01535 - CBN01535 - CBN01535 - CBN01535.1 - CN16720 taxonomy: c_brenneri other_names: - CBN01535 - CBN01535 - CBN01535 - CBN01535.1 - CN16720 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00140260 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: CJA38643 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00214490 label: CJA38643 other_names: - CJA38643 - CJA38643.1 - JA62734 - CJA38643 taxonomy: c_japonica other_names: - CJA38643 - CJA38643.1 - JA62734 - CJA38643 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00214490 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Ppa-unc-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00117349 label: Ppa-unc-18 other_names: - PPA27795 - UMM-S13-21.60 - GENEPREDICTION_SNAP300000084620 - PP69402 - PPA27795 - PPA27795.1 taxonomy: p_pacificus other_names: - PPA27795 - UMM-S13-21.60 - GENEPREDICTION_SNAP300000084620 - PP69402 - PPA27795 - PPA27795.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00117349 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: TMUE_3000011930 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00290156 label: TMUE_3000011930 other_names: - TMUE_3000011930 - TMUE_s0053003100 - TMUE_3000011930.3 - TMP09906 - TMUE_3000011930 - TMUE_3000011930.2 - TMUE_3000011930.1 taxonomy: t_muris other_names: - TMUE_3000011930 - TMUE_s0053003100 - TMUE_3000011930.3 - TMP09906 - TMUE_3000011930 - TMUE_3000011930.2 - TMUE_3000011930.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00290156 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in neuropeptide signaling pathway. Is an ortholog of C. elegans flp-18. In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. label: Cbn-flp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans flp-18. - In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction id: WBGene00142461 label: Cbn-flp-18 other_names: - CBN03736 - CBN03736 - CBN03736.1 - CN20816 - CBN03736 taxonomy: c_brenneri other_names: - CBN03736 - CBN03736 - CBN03736.1 - CN20816 - CBN03736 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00142461 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Cbn-unc-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00155616 label: Cbn-unc-18 other_names: - CBN16891 - CBN16891 - CN22107 - CBN16891.1 - CBN16891 taxonomy: c_brenneri other_names: - CBN16891 - CBN16891 - CN22107 - CBN16891.1 - CBN16891 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00155616 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Cbr-unc-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00036613 label: Cbr-unc-18 other_names: - CBG16760 - CBG_16760 - CBG16760 - CBP03998 - CBG16760.1 taxonomy: c_briggsae other_names: - CBG16760 - CBG_16760 - CBG16760 - CBP03998 - CBG16760.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00036613 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Saposin B type domain. Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response." label: Cre-spp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response. id: WBGene00072225 label: Cre-spp-18 other_names: - CRE13498 - cr01.sctg327.wum.1 - CRE13498.1 - RP27179 - CRE13498 taxonomy: c_remanei other_names: - CRE13498 - cr01.sctg327.wum.1 - CRE13498.1 - RP27179 - CRE13498 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00072225 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Bma-unc-18.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00221426 label: Bma-unc-18.1 other_names: - Bm1165 - TAG1165 - Bm1_29825A - Bm1_29825 - Bm1165b.1 - BM23277 - Bm1165a - BM27838 - Bm1165b - Bm1165a.1 taxonomy: b_malayi other_names: - Bm1165 - TAG1165 - Bm1_29825A - Bm1_29825 - Bm1165b.1 - BM23277 - Bm1165a - BM27838 - Bm1165b - Bm1165a.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00221426 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Cre-unc-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00051283 label: Cre-unc-18 other_names: - CRE00513 - cr01.sctg0.wum.289 - CRE00513 - CRE00513.1 - RP02038 taxonomy: c_remanei other_names: - CRE00513 - cr01.sctg0.wum.289 - CRE00513 - CRE00513.1 - RP02038 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00051283 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: SRAE_2000442700 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00264659 label: SRAE_2000442700 other_names: - SRAE_2000442700 - SRP03057 - SRAE_2000442700.1 - SRAE_2000442700 taxonomy: s_ratti other_names: - SRAE_2000442700 - SRP03057 - SRAE_2000442700.1 - SRAE_2000442700 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00264659 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: SRAE_X000230800 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00267891 label: SRAE_X000230800 other_names: - SRAE_X000230800 - SRP06341 - SRAE_X000230800.1 - SRAE_X000230800 taxonomy: s_ratti other_names: - SRAE_X000230800 - SRP06341 - SRAE_X000230800.1 - SRAE_X000230800 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00267891 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-9; nspc-18; and nspc-1. label: CBG14036 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-9; nspc-18; and nspc-1. id: WBGene00034677 label: CBG14036 other_names: - CBG14036 - CBG_14036 - CBP33561 - CBG14036 - CBG14036.1 taxonomy: c_briggsae other_names: - CBG14036 - CBG_14036 - CBP33561 - CBG14036 - CBG14036.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00034677 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-16; nspc-18; and nspc-19. label: CJA21165 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-16; nspc-18; and nspc-19. id: WBGene00176737 label: CJA21165 other_names: - CJA21165 - JA45393 - CJA21165 - CJA21165.1 taxonomy: c_japonica other_names: - CJA21165 - JA45393 - CJA21165 - CJA21165.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00176737 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-16; nspc-18; and nspc-19. label: CJA41060 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-16; nspc-18; and nspc-19. id: WBGene00216908 label: CJA41060 other_names: - CJA41060 - JA61905 - CJA41060 - CJA41060.1 taxonomy: c_japonica other_names: - CJA41060 - JA61905 - CJA41060 - CJA41060.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00216908 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. label: CRE17492 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. id: WBGene00068573 label: CRE17492 other_names: - CRE17492 - cr01.sctg121.wum.11 - CRE17492.1 - CRE17492 - RP38922 taxonomy: c_remanei other_names: - CRE17492 - cr01.sctg121.wum.11 - CRE17492.1 - CRE17492 - RP38922 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00068573 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-9; nspc-10; and nspc-18. label: CBG01112 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-9; nspc-10; and nspc-18. id: WBGene00024390 label: CBG01112 other_names: - CBG01112 - CBG_01112 - CBP06014 - CBG01112.1 - CBG01112 taxonomy: c_briggsae other_names: - CBG01112 - CBG_01112 - CBP06014 - CBG01112.1 - CBG01112 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00024390 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: Cbr-sup-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00033243 label: Cbr-sup-18 other_names: - CBG12270 - CBG_12270 - CBP38029 - CBG12270.1 - CBG12270 taxonomy: c_briggsae other_names: - CBG12270 - CBG_12270 - CBP38029 - CBG12270.1 - CBG12270 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00033243 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans pals-25; pals-19; and pals-18. label: CJA36552 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans pals-25; pals-19; and pals-18. id: WBGene00212399 label: CJA36552 other_names: - CJA36552 - CJA36552 - JA09397 - CJA36552.1 - CJA36552.2 taxonomy: c_japonica other_names: - CJA36552 - CJA36552 - JA09397 - CJA36552.1 - CJA36552.2 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00212399 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: Cjp-sup-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00130949 label: Cjp-sup-18 other_names: - CJA11745 - CJA11745a.1 - CJA11745c.1 - JA56050 - JA49927 - CJA11745b - CJA11745a - JA52910 - CJA11745c - CJA11745b.1 taxonomy: c_japonica other_names: - CJA11745 - CJA11745a.1 - CJA11745c.1 - JA56050 - JA49927 - CJA11745b - CJA11745a - JA52910 - CJA11745c - CJA11745b.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00130949 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans gly-19; gly-18; and gly-16. label: CRE07851 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans gly-19; gly-18; and gly-16. id: WBGene00069898 label: CRE07851 other_names: - CRE07851 - cr01.sctg164.wum.4 - CRE07851.1 - RP38791 - CRE07851 taxonomy: c_remanei other_names: - CRE07851 - cr01.sctg164.wum.4 - CRE07851.1 - RP38791 - CRE07851 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00069898 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. label: CRE21029 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. id: WBGene00085521 label: CRE21029 other_names: - CRE21029 - CRE21029 - CRE21029.1 - RP31127 taxonomy: c_remanei other_names: - CRE21029 - CRE21029 - CRE21029.1 - RP31127 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00085521 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: OVOC5015 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00241824 label: OVOC5015 other_names: - OVOC5015 - OVP14113 - OVOC5015.1 - OVOC5015 taxonomy: o_volvulus other_names: - OVOC5015 - OVP14113 - OVOC5015.1 - OVOC5015 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00241824 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like. Is an ortholog of C. elegans mig-18." label: Bma-mig-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." - Is an ortholog of C. elegans mig-18. id: WBGene00223573 label: Bma-mig-18 other_names: - Bm3312 - Bm1_50515 - TAG3312 - BM31015 - Bm3312 - Bm3312.1 taxonomy: b_malayi other_names: - Bm3312 - Bm1_50515 - TAG3312 - BM31015 - Bm3312 - Bm3312.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00223573 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Bma-unc-18.2 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00234090 label: Bma-unc-18.2 other_names: - Bm13829 - TAG13829 - Bm1_07435A - Bm1_16115 - Bm1_16115A - BM23673 - Bm13829.1 - Bm13829 taxonomy: b_malayi other_names: - Bm13829 - TAG13829 - Bm1_07435A - Bm1_16115 - Bm1_16115A - BM23673 - Bm13829.1 - Bm13829 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00234090 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in neuropeptide signaling pathway. Is an ortholog of C. elegans flp-18. In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. label: Cbr-flp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans flp-18. - In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction id: WBGene00034717 label: Cbr-flp-18 other_names: - CBG14115 - CBG_14115 - CBG14115 - CBG14115.1 - CBP34912 taxonomy: c_briggsae other_names: - CBG14115 - CBG_14115 - CBG14115 - CBG14115.1 - CBP34912 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00034717 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Saposin B type domain. Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response." label: Cjp-spp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans spp-18. In C. elegans, spp-18 is involved in innate immune response. id: WBGene00131227 label: Cjp-spp-18 other_names: - CJA12023 - CJA12023.1 - CJA12023 - JA08091 taxonomy: c_japonica other_names: - CJA12023 - CJA12023.1 - CJA12023 - JA08091 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00131227 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Cjp-unc-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00135188 label: Cjp-unc-18 other_names: - CJA15984 - CJA15984.1 - JA17753 - CJA15984 taxonomy: c_japonica other_names: - CJA15984 - CJA15984.1 - JA17753 - CJA15984 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00135188 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in neuropeptide signaling pathway. Is an ortholog of C. elegans flp-18. In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction; and sleep. label: Cre-flp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans flp-18. - In C. elegans, flp-18 is involved in neuropeptide signaling pathway; regulation of muscle contraction id: WBGene00052061 label: Cre-flp-18 other_names: - CRE00446 - cr01.sctg0.wum.1038 - CRE00446.1 - RP06927 - CRE00446 taxonomy: c_remanei other_names: - CRE00446 - cr01.sctg0.wum.1038 - CRE00446.1 - RP06927 - CRE00446 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00052061 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in vesicle-mediated transport. Is an ortholog of C. elegans unc-18. In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter secretion. label: Ovo-unc-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans unc-18. - In C. elegans, unc-18 is involved in chemical synaptic transmission and positive regulation of neurotransmitter id: WBGene00239568 label: Ovo-unc-18 other_names: - OVOC2759 - OVP06317 - OVOC2759 - OVOC2759.1 taxonomy: o_volvulus other_names: - OVOC2759 - OVP06317 - OVOC2759 - OVOC2759.1 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00239568 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-9; nspc-10; and nspc-18. label: CBG01129 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-9; nspc-10; and nspc-18. id: WBGene00024405 label: CBG01129 other_names: - CBG01129 - CBG_01129 - CBP49940 - CBG01129 - CBG01129.1 taxonomy: c_briggsae other_names: - CBG01129 - CBG_01129 - CBP49940 - CBG01129 - CBG01129.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00024405 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans gly-19; gly-18; and gly-16. label: CBN30858 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans gly-19; gly-18; and gly-16. id: WBGene00192823 label: CBN30858 other_names: - CBN30858 - CN33212 - CBN30858 - CBN30858.1 taxonomy: c_brenneri other_names: - CBN30858 - CN33212 - CBN30858 - CBN30858.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00192823 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: CJA41529 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00217377 label: CJA41529 other_names: - CJA41529 - CJA41529b.1 - JA56749 - CJA41529a - JA50766 - CJA41529b - CJA41529a.1 taxonomy: c_japonica other_names: - CJA41529 - CJA41529b.1 - JA56749 - CJA41529a - JA50766 - CJA41529b - CJA41529a.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00217377 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: Cre-sup-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00071541 label: Cre-sup-18 other_names: - CRE25916 - cr01.sctg259.wum.2 - RP38819 - CRE25916.1 - CRE25916 taxonomy: c_remanei other_names: - CRE25916 - cr01.sctg259.wum.2 - RP38819 - CRE25916.1 - CRE25916 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00071541 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. label: CRE17484 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. id: WBGene00068582 label: CRE17484 other_names: - CRE17484 - cr01.sctg121.wum.20 - RP24206 - CRE17484 - CRE17484.1 taxonomy: c_remanei other_names: - CRE17484 - cr01.sctg121.wum.20 - RP24206 - CRE17484 - CRE17484.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00068582 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. label: CRE17490 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. id: WBGene00068576 label: CRE17490 other_names: - CRE17490 - cr01.sctg121.wum.14 - RP17427 - CRE17490 - CRE17490.1 taxonomy: c_remanei other_names: - CRE17490 - cr01.sctg121.wum.14 - RP17427 - CRE17490 - CRE17490.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00068576 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. label: CRE17504 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-17; nspc-18; and nspc-20. id: WBGene00068583 label: CRE17504 other_names: - CRE17504 - cr01.sctg121.wum.21 - CRE17504 - RP06915 - CRE17504.1 taxonomy: c_remanei other_names: - CRE17504 - cr01.sctg121.wum.21 - CRE17504 - RP06915 - CRE17504.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00068583 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Is an ortholog of C. elegans nspc-10; nspc-18; and nspc-1. label: CBG01113 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans nspc-10; nspc-18; and nspc-1. id: WBGene00024391 label: CBG01113 other_names: - CBG01113 - CBG_01113 - CBP45993 - CBG01113.1 - CBG01113 taxonomy: c_briggsae other_names: - CBG01113 - CBG_01113 - CBP45993 - CBG01113.1 - CBG01113 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00024391 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable oxidoreductase activity. Is an ortholog of C. elegans sup-18. label: Cbn-sup-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans sup-18. id: WBGene00191391 label: Cbn-sup-18 other_names: - CBN29426 - CBN29426 - CN34778 - CBN29426.1 taxonomy: c_brenneri other_names: - CBN29426 - CBN29426 - CN34778 - CBN29426.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00191391 - allele: - class: variation id: WBVar01083560 label: gk779770 - class: variation id: WBVar01083561 label: gk428313 - class: variation id: WBVar01083557 label: gk883058 - class: variation id: WBVar01083569 label: gk623860 - class: variation id: WBVar01083559 label: gk370980 - class: variation id: WBVar01499524 label: gk963587 - class: variation id: WBVar00482373 label: gk259130 - class: variation id: WBVar01083568 label: gk397735 - class: variation id: WBVar01499446 label: gk963489 - class: variation id: WBVar01083565 label: gk812666 - class: variation id: WBVar01083566 label: gk631275 - class: variation id: WBVar01498549 label: gk963304 - class: variation id: WBVar02146755 label: tm8492 - class: variation id: WBVar00482374 label: gk259131 - class: variation id: WBVar00482375 label: gk259132 - class: variation id: WBVar00482378 label: gk259135 - class: variation id: WBVar01083571 label: gk741826 - class: variation id: WBVar00482377 label: gk259134 - class: variation id: WBVar01083567 label: gk600120 - class: variation id: WBVar00482376 label: gk259133 - class: variation id: WBVar02137928 label: h8593 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01083564 label: gk837195 - class: variation id: WBVar00482372 label: gk259129 - class: variation id: WBVar01083563 label: gk894889 - class: variation id: WBVar01083562 label: gk831722 - class: variation id: WBVar01498290 label: gk962630 - class: variation id: WBVar01498710 label: gk964050 - class: variation id: WBVar01083558 label: gk490601 - class: variation id: WBVar01083570 label: gk853124 - class: variation id: WBVar01499525 label: gk963588 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by several genes including clk-1; pgl-1; and daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by nine chemicals including Alovudine; Sodium Chloride; and Rifampin based on RNA-seq and microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF684) and Protein of unknown function DUF684." label: Y102A5C.4 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including clk-1; pgl-1; and daf-18 based on tiling array; microarray; and id: WBGene00013613 label: Y102A5C.4 other_names: - Y102A5C.4 - CELE_Y102A5C.4 - Y102A5C.4.1 - CE48246 - Y102A5C.4 taxonomy: c_elegans other_names: - Y102A5C.4 - CELE_Y102A5C.4 - Y102A5C.4.1 - CE48246 - Y102A5C.4 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00013613 - allele: - class: variation id: WBVar00677779 label: gk620001 - class: variation id: WBVar00677788 label: gk708003 - class: variation id: WBVar00677777 label: gk315910 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar01499647 label: gk963738 - class: variation id: WBVar00677783 label: gk819867 - class: variation id: WBVar00347783 label: gk124540 - class: variation id: WBVar02128686 label: h5226 - class: variation id: WBVar00677780 label: gk881270 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar01500019 label: gk964201 - class: variation id: WBVar00677792 label: gk785137 - class: variation id: WBVar00677789 label: gk881701 - class: variation id: WBVar01499055 label: gk962859 - class: variation id: WBVar00677784 label: gk888054 - class: variation id: WBVar00347785 label: gk124542 - class: variation id: WBVar00677776 label: gk553058 - class: variation id: WBVar00677775 label: gk732839 - class: variation id: WBVar00677795 label: gk565014 - class: variation id: WBVar02128685 label: h10216 - class: variation id: WBVar00677791 label: gk340957 - class: variation id: WBVar00677778 label: gk754229 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00677774 label: gk860915 - class: variation id: WBVar00677786 label: gk471656 - class: variation id: WBVar00677781 label: gk381178 - class: variation id: WBVar01500020 label: gk964202 - class: variation id: WBVar00347787 label: gk124544 - class: variation id: WBVar00347788 label: gk124545 - class: variation id: WBVar00347784 label: gk124541 - class: variation id: WBVar00677787 label: gk428774 - class: variation id: WBVar00677794 label: gk784467 - class: variation id: WBVar00677790 label: gk924675 - class: variation id: WBVar02146276 label: tm8303 - class: variation id: WBVar00677782 label: gk507779 - class: variation id: WBVar00677793 label: gk378213 - class: variation id: WBVar00677785 label: gk536077 - class: variation id: WBVar01499204 label: gk963095 - class: variation id: WBVar00347786 label: gk124543 dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Enriched in neurons based on RNA-seq studies. Is affected by several genes including daf-12; clk-1; and daf-18 based on tiling array; microarray; and RNA-seq studies. Is affected by methylmercuric chloride based on microarray studies. Is predicted to encode a protein with the following domains: Protein of unknown function (DUF1647) and Protein of unknown function DUF1647." label: F41D3.9 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including daf-12; clk-1; and daf-18 based on tiling array; microarray; and id: WBGene00009614 label: F41D3.9 other_names: - F41D3.9 - CELE_F41D3.9 - CE16028 - F41D3.9 - F41D3.9.1 taxonomy: c_elegans other_names: - F41D3.9 - CELE_F41D3.9 - CE16028 - F41D3.9 - F41D3.9.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00009614 - allele: - class: variation id: WBVar01144450 label: gk748484 - class: variation id: WBVar01144448 label: gk550719 - class: variation id: WBVar01144436 label: gk825548 - class: variation id: WBVar01144433 label: gk523460 - class: variation id: WBVar01144446 label: gk927968 - class: variation id: WBVar01144430 label: gk791082 - class: variation id: WBVar01144452 label: gk811161 - class: variation id: WBVar01144435 label: gk625551 - class: variation id: WBVar01144434 label: gk339467 - class: variation id: WBVar01144449 label: gk602367 - class: variation id: WBVar00502716 label: gk279473 - class: variation id: WBVar00502714 label: gk279471 - class: variation id: WBVar01144442 label: gk480747 - class: variation id: WBVar01144454 label: gk737442 - class: variation id: WBVar00145722 label: gk315 - class: variation id: WBVar01144440 label: gk358454 - class: variation id: WBVar00502715 label: gk279472 - class: variation id: WBVar01144445 label: gk760871 - class: variation id: WBVar01144438 label: gk355699 - class: variation id: WBVar00502720 label: gk279477 - class: variation id: WBVar01144444 label: gk330330 - class: variation id: WBVar01144429 label: gk376969 - class: variation id: WBVar00502721 label: gk279478 - class: variation id: WBVar01144439 label: gk316528 - class: variation id: WBVar00502717 label: gk279474 - class: variation id: WBVar01144428 label: gk626336 - class: variation id: WBVar01144441 label: gk636959 - class: variation id: WBVar01144431 label: gk705674 - class: variation id: WBVar01144453 label: gk549436 - class: variation id: WBVar01144447 label: gk427690 - class: variation id: WBVar01144432 label: gk355698 - class: variation id: WBVar00502718 label: gk279475 - class: variation id: WBVar01144427 label: gk661124 - class: variation id: WBVar00502723 label: gk279480 - class: variation id: WBVar01144457 label: gk323558 - class: variation id: WBVar01144443 label: gk448437 - class: variation id: WBVar00502722 label: gk279479 - class: variation id: WBVar01144455 label: gk839074 - class: variation id: WBVar01144456 label: gk931823 - class: variation id: WBVar01144437 label: gk416440 - class: variation id: WBVar00502719 label: gk279476 - class: variation id: WBVar01144451 label: gk859320 - class: variation id: WBVar01500067 label: gk964260 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enables histone H3K4 methyltransferase activity. Predicted to be involved in chromatin remodeling. Predicted to be located in nucleus. label: set-30 legacy_description: set-30 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18; neither set-30(gk314) nor set-30(RNAi) have any obvious phenotypes. merged_into: ~ name: class: gene highlight: description_all: - 606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-30 is paralogous to SET-10, SET-14, and SET-18 id: WBGene00022499 label: set-30 other_names: - ZC8.3 - CELE_ZC8.3 - tag-226 - CE33744 - ZC8.3 - ZC8.3.1 taxonomy: c_elegans other_names: - ZC8.3 - CELE_ZC8.3 - tag-226 - CE33744 - ZC8.3 - ZC8.3.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00022499 - allele: - class: variation id: WBVar02128979 label: h10848 - class: variation id: WBVar00688588 label: gk812820 - class: variation id: WBVar00688594 label: gk438389 - class: variation id: WBVar00351452 label: gk128209 - class: variation id: WBVar00688586 label: gk535012 - class: variation id: WBVar00688604 label: gk492511 - class: variation id: WBVar00688599 label: gk879527 - class: variation id: WBVar00688597 label: gk874561 - class: variation id: WBVar00351450 label: gk128207 - class: variation id: WBVar00688605 label: gk340972 - class: variation id: WBVar02128980 label: h10221 - class: variation id: WBVar00688602 label: gk547939 - class: variation id: WBVar00688590 label: gk666955 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar00688611 label: gk450830 - class: variation id: WBVar00688591 label: gk795766 - class: variation id: WBVar00688592 label: gk638087 - class: variation id: WBVar00688608 label: gk898932 - class: variation id: WBVar00351446 label: gk128203 - class: variation id: WBVar00688609 label: gk450829 - class: variation id: WBVar00688595 label: gk930317 - class: variation id: WBVar00688593 label: gk435934 - class: variation id: WBVar00688610 label: gk881284 - class: variation id: WBVar00688584 label: gk715702 - class: variation id: WBVar00351448 label: gk128205 - class: variation id: WBVar00688596 label: gk519400 - class: variation id: WBVar00688606 label: gk924190 - class: variation id: WBVar00688598 label: gk672841 - class: variation id: WBVar00688587 label: gk608434 - class: variation id: WBVar00688600 label: gk316925 - class: variation id: WBVar00688583 label: gk378639 - class: variation id: WBVar00688603 label: gk812425 - class: variation id: WBVar00351451 label: gk128208 - class: variation id: WBVar00351449 label: gk128206 - class: variation id: WBVar00688585 label: gk536092 - class: variation id: WBVar00351447 label: gk128204 - class: variation id: WBVar01498939 label: gk962681 - class: variation id: WBVar01499823 label: gk963947 - class: variation id: WBVar00688589 label: gk514427 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00688601 label: gk695209 - class: variation id: WBVar00142591 label: cxTi10629 - class: variation id: WBVar00688607 label: gk881283 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Enriched in several structures, including ABalaaaarl; ABalaaaarr; ABplaapaaa; hyp3; and interfacial epithelial cell based on single-cell RNA-seq studies. Is affected by several genes including clk-1; daf-18; and sma-2 based on microarray; tiling array; and RNA-seq studies. Is affected by eight chemicals including methylmercuric chloride; Alovudine; and stavudine based on microarray and RNA-seq studies. label: Y71A12B.15 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is affected by several genes including clk-1; daf-18; and sma-2 based on microarray; tiling array; and id: WBGene00013511 label: Y71A12B.15 other_names: - Y71A12B.15 - Y71A12B.s - CELE_Y71A12B.15 - Y71A12B.15 taxonomy: c_elegans other_names: - Y71A12B.15 - Y71A12B.s - CELE_Y71A12B.15 - Y71A12B.15 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00013511 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: OVOC379 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00237188 label: OVOC379 other_names: - OVOC379 - OVP06519 - OVOC379.1 - OVOC379 taxonomy: o_volvulus other_names: - OVOC379 - OVP06519 - OVOC379.1 - OVOC379 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00237188 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: CBN17935 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00156660 label: CBN17935 other_names: - CBN17935 - CBN17935.1 - CBN17935 - CN25861 taxonomy: c_brenneri other_names: - CBN17935 - CBN17935.1 - CBN17935 - CN25861 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00156660 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: CBN19215 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00157940 label: CBN19215 other_names: - CBN19215 - CBN19215 - CN21389 - CBN19215.1 taxonomy: c_brenneri other_names: - CBN19215 - CBN19215 - CN21389 - CBN19215.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00157940 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "PHENOTYPE: Homozygous null mice exhibit defective IL-18-mediated immune responses such as the inability of splenocytes, T helper 1 cells and neutrophils to produce cytokines in response to IL-18. [provided by MGI curators]" label: Il18rap legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "PHENOTYPE: Homozygous null mice exhibit defective IL-18-mediated immune responses such as the inability" - of splenocytes, T helper 1 cells and neutrophils to produce cytokines in response to IL-18. id: MGI:1338888 label: Il18rap other_names: - ~ taxonomy: m_musculus other_names: - ~ page_type: gene species: key: m_musculus name: Mus musculus taxonomy: genus: Mus id: m_musculus species: musculus wbid: MGI:1338888 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: CRE09637 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00070020 label: CRE09637 other_names: - CRE09637 - cr01.sctg168.wum.20 - CRE09637.1 - CRE09637 - RP15971 taxonomy: c_remanei other_names: - CRE09637 - cr01.sctg168.wum.20 - CRE09637.1 - CRE09637 - RP15971 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00070020 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: PPA10747 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00100301 label: PPA10747 other_names: - PPA10747 - GENEPREDICTION_SNAP300000071807 - UMS-S13-63.35 - PPA10747.1 - PPA10747 - PP68565 taxonomy: p_pacificus other_names: - PPA10747 - GENEPREDICTION_SNAP300000071807 - UMS-S13-63.35 - PPA10747.1 - PPA10747 - PP68565 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00100301 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: SRAE_1000208800 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00258700 label: SRAE_1000208800 other_names: - SRAE_1000208800 - SRP07395 - SRAE_1000208800.1 - SRAE_1000208800 taxonomy: s_ratti other_names: - SRAE_1000208800 - SRP07395 - SRAE_1000208800.1 - SRAE_1000208800 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00258700 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-23. In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. label: Cbr-mab-23 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-23. - In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination id: WBGene00031215 label: Cbr-mab-23 other_names: - CBG09659 - CBG_09659 - CBP41551 - CBG09659.1 - CBG09659 taxonomy: c_briggsae other_names: - CBG09659 - CBG_09659 - CBP41551 - CBG09659.1 - CBG09659 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00031215 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable coreceptor activity and interleukin-18 receptor activity. Involved in cellular response to cytokine stimulus and cellular response to hydrogen peroxide. Predicted to be part of interleukin-18 receptor complex. Orthologous to human IL18RAP (interleukin 18 receptor accessory protein); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide. label: Il18rap legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Predicted to enable coreceptor activity and interleukin-18 receptor activity. - Predicted to be part of interleukin-18 receptor complex. - Orthologous to human IL18RAP (interleukin 18 receptor accessory protein); PARTICIPATES IN interleukin id: RGD:727867 label: Il18rap other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:727867 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: SRAE_X000103200 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00266595 label: SRAE_X000103200 other_names: - SRAE_X000103200 - SR03237 - SRAE_X000103200 - SRAE_X000103200.1 - SRP05679 taxonomy: s_ratti other_names: - SRAE_X000103200 - SR03237 - SRAE_X000103200 - SRAE_X000103200.1 - SRP05679 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00266595 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable chloride channel activity. Is an ortholog of C. elegans best-18. label: Bma-best-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans best-18. id: WBGene00230935 label: Bma-best-18 other_names: - Bm10674 - TAG5868 - TAG10674 - Bm10674 - BM39829 - Bm10674.1 taxonomy: b_malayi other_names: - Bm10674 - TAG5868 - TAG10674 - Bm10674 - BM39829 - Bm10674.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00230935 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: Cbn-npp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00157515 label: Cbn-npp-18 other_names: - CBN18790 - CBN18790 - CBN18790.1 - CN03419 - CBN18790 taxonomy: c_brenneri other_names: - CBN18790 - CBN18790 - CBN18790.1 - CN03419 - CBN18790 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00157515 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable UDP-glycosyltransferase activity. Is an ortholog of C. elegans ugt-18. label: Cbr-ugt-18.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ugt-18. id: WBGene00042767 label: Cbr-ugt-18.1 other_names: - CBG24724 - CBG_24724 - CBG24724.1 - CBP43043 - CBG24724 taxonomy: c_briggsae other_names: - CBG24724 - CBG_24724 - CBG24724.1 - CBP43043 - CBG24724 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00042767 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable chloride channel activity. Is an ortholog of C. elegans best-18. label: Cre-best-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans best-18. id: WBGene00054925 label: Cre-best-18 other_names: - CRE25496 - cr01.sctg4.wum.279 - CRE25496 - CRE25496.1 - RP46588 taxonomy: c_remanei other_names: - CRE25496 - cr01.sctg4.wum.279 - CRE25496 - CRE25496.1 - RP46588 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00054925 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Orthologous to human C18orf63 (chromosome 18 open reading frame 63); INTERACTS WITH tebuconazole (ortholog). label: LOC100359752 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Orthologous to human C18orf63 (chromosome 18 open reading frame 63); INTERACTS WITH tebuconazole (ortholog id: RGD:2323488 label: LOC100359752 other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:2323488 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable chloride channel activity. Is an ortholog of C. elegans best-18. label: Cbr-best-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans best-18. id: WBGene00031329 label: Cbr-best-18 other_names: - CBG09809 - CBG_09809 - CBG09809.1 - CBG09809 - CBP16655 taxonomy: c_briggsae other_names: - CBG09809 - CBG_09809 - CBG09809.1 - CBG09809 - CBP16655 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00031329 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable UDP-glycosyltransferase activity. Is an ortholog of C. elegans ugt-18. label: Cbr-ugt-18.2 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ugt-18. id: WBGene00030362 label: Cbr-ugt-18.2 other_names: - CBG08603 - CBG_08603 - CBP16291 - CBG08603.1 - CBG08603 taxonomy: c_briggsae other_names: - CBG08603 - CBG_08603 - CBP16291 - CBG08603.1 - CBG08603 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00030362 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans tsp-18. label: Cre-tsp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tsp-18. id: WBGene00084796 label: Cre-tsp-18 other_names: - CRE26593 - CRE26593.1 - CRE26593 - RP50180 taxonomy: c_remanei other_names: - CRE26593 - CRE26593.1 - CRE26593 - RP50180 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00084796 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: Bma-npp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00226799 label: Bma-npp-18 other_names: - Bm6538 - TAG6538 - Bm1_18460 - Bm-npp-18 - Bm1_18455 - Bm1_18455A - Bm6538.1 - BM24649 - Bm6538 taxonomy: b_malayi other_names: - Bm6538 - TAG6538 - Bm1_18460 - Bm-npp-18 - Bm1_18455 - Bm1_18455A - Bm6538.1 - BM24649 - Bm6538 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226799 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans tsp-18. label: Cbn-tsp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tsp-18. id: WBGene00154775 label: Cbn-tsp-18 other_names: - CBN16050 - CBN16050.1 - CN15718 - CBN16050 taxonomy: c_brenneri other_names: - CBN16050 - CBN16050.1 - CN15718 - CBN16050 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00154775 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: CJA31862 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00207709 label: CJA31862 other_names: - CJA31862 - JA59772 - CJA31862b.1 - JA64747 - CJA31862b - CJA31862a.1 - CJA31862a taxonomy: c_japonica other_names: - CJA31862 - JA59772 - CJA31862b.1 - JA64747 - CJA31862b - CJA31862a.1 - CJA31862a page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00207709 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable chloride channel activity. Is an ortholog of C. elegans best-18. label: Cjp-best-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans best-18. id: WBGene00121122 label: Cjp-best-18 other_names: - CJA01918 - JA30483 - CJA01918 - CJA01918.1 taxonomy: c_japonica other_names: - CJA01918 - JA30483 - CJA01918 - CJA01918.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00121122 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: Cjp-npp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00138381 label: Cjp-npp-18 other_names: - CJA19177 - JA41976 - CJA19177b - CJA19177a.2 - CJA19177a.1 - CJA19177a - JA45677 - CJA19177b.1 taxonomy: c_japonica other_names: - CJA19177 - JA41976 - CJA19177b - CJA19177a.2 - CJA19177a.1 - CJA19177a - JA45677 - CJA19177b.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00138381 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans tsp-18. label: Cjp-tsp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tsp-18. id: WBGene00137061 label: Cjp-tsp-18 other_names: - CJA17857 - CJA17857.1 - CJA17857 - JA59150 taxonomy: c_japonica other_names: - CJA17857 - CJA17857.1 - CJA17857 - JA59150 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00137061 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: Cre-npp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00061548 label: Cre-npp-18 other_names: - CRE13292 - cr01.sctg25.wum.50 - RP00994 - CRE13292.1 - CRE13292 - CRE13292.2 taxonomy: c_remanei other_names: - CRE13292 - cr01.sctg25.wum.50 - RP00994 - CRE13292.1 - CRE13292 - CRE13292.2 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00061548 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable UDP-glycosyltransferase activity. Is an ortholog of C. elegans ugt-18. label: Cre-ugt-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ugt-18. id: WBGene00052643 label: Cre-ugt-18 other_names: - CRE27167 - cr01.sctg1.wum.515 - CRE27167 - CRE27167.1 - RP34130 taxonomy: c_remanei other_names: - CRE27167 - cr01.sctg1.wum.515 - CRE27167 - CRE27167.1 - RP34130 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00052643 - allele: - class: variation id: WBVar00675096 label: gk690276 - class: variation id: WBVar00675105 label: gk545004 - class: variation id: WBVar00675157 label: gk650179 - class: variation id: WBVar00675143 label: gk916873 - class: variation id: WBVar00675149 label: gk428427 - class: variation id: WBVar00346882 label: gk123639 - class: variation id: WBVar00675093 label: gk456582 - class: variation id: WBVar00346899 label: gk123656 - class: variation id: WBVar00675108 label: gk640210 - class: variation id: WBVar00346876 label: gk123633 - class: variation id: WBVar00346874 label: gk123631 - class: variation id: WBVar00675154 label: gk712604 - class: variation id: WBVar00675097 label: gk339944 - class: variation id: WBVar00675112 label: gk640211 - class: variation id: WBVar00675137 label: gk637074 - class: variation id: WBVar00346877 label: gk123634 - class: variation id: WBVar00675162 label: gk744485 - class: variation id: WBVar01495787 label: gk960050 - class: variation id: WBVar00675131 label: gk781627 - class: variation id: WBVar00675091 label: gk565008 - class: variation id: WBVar00346884 label: gk123641 - class: variation id: WBVar00675126 label: gk801214 - class: variation id: WBVar00675118 label: gk650921 - class: variation id: WBVar00675129 label: gk937168 - class: variation id: WBVar02128614 label: h3252 - class: variation id: WBVar00675107 label: gk807342 - class: variation id: WBVar00675127 label: gk620423 - class: variation id: WBVar00675136 label: gk531336 - class: variation id: WBVar00675159 label: gk742017 - class: variation id: WBVar00675099 label: gk840457 - class: variation id: WBVar01498959 label: gk962706 - class: variation id: WBVar00346895 label: gk123652 - class: variation id: WBVar00675106 label: gk337450 - class: variation id: WBVar00346883 label: gk123640 - class: variation id: WBVar00675116 label: gk500503 - class: variation id: WBVar00675145 label: gk447404 - class: variation id: WBVar00675111 label: gk506907 - class: variation id: WBVar00346878 label: gk123635 - class: variation id: WBVar00675166 label: gk706397 - class: variation id: WBVar00675165 label: gk425781 - class: variation id: WBVar00675101 label: gk739395 - class: variation id: WBVar00675098 label: gk886191 - class: variation id: WBVar00675124 label: gk875883 - class: variation id: WBVar01476252 label: gk940509 - class: variation id: WBVar00675161 label: gk777875 - class: variation id: WBVar00598050 label: gk309041 - class: variation id: WBVar02151796 label: tm11463 - class: variation id: WBVar00675152 label: gk487332 - class: variation id: WBVar00675134 label: gk514060 - class: variation id: WBVar00305007 label: otn8186 - class: variation id: WBVar00346891 label: gk123648 - class: variation id: WBVar00346888 label: gk123645 - class: variation id: WBVar00346885 label: gk123642 - class: variation id: WBVar00675095 label: gk645612 - class: variation id: WBVar00675102 label: gk321712 - class: variation id: WBVar00675123 label: gk895926 - class: variation id: WBVar00675089 label: gk413572 - class: variation id: WBVar00675133 label: gk428107 - class: variation id: WBVar00675135 label: gk671123 - class: variation id: WBVar00346892 label: gk123649 - class: variation id: WBVar00346893 label: gk123650 - class: variation id: WBVar00346897 label: gk123654 - class: variation id: WBVar00346896 label: gk123653 - class: variation id: WBVar02128613 label: h11181 - class: variation id: WBVar00675128 label: gk525674 - class: variation id: WBVar00675142 label: gk472503 - class: variation id: WBVar00675144 label: gk354772 - class: variation id: WBVar00346894 label: gk123651 - class: variation id: WBVar00675156 label: gk472993 - class: variation id: WBVar00675153 label: gk487333 - class: variation id: WBVar01499788 label: gk963906 - class: variation id: WBVar00675148 label: gk552549 - class: variation id: WBVar00675094 label: gk516688 - class: variation id: WBVar00346889 label: gk123646 - class: variation id: WBVar01499055 label: gk962859 - class: variation id: WBVar00066909 label: cxTi5205 - class: variation id: WBVar00675139 label: gk822062 - class: variation id: WBVar00346886 label: gk123643 - class: variation id: WBVar00675122 label: gk827185 - class: variation id: WBVar00346887 label: gk123644 - class: variation id: WBVar00675104 label: gk912686 - class: variation id: WBVar00675130 label: gk313987 - class: variation id: WBVar00675151 label: gk459255 - class: variation id: WBVar00675164 label: gk837404 - class: variation id: WBVar00346900 label: gk123657 - class: variation id: WBVar00346902 label: gk123659 - class: variation id: WBVar00346881 label: gk123638 - class: variation id: WBVar00277788 label: gk1357 - class: variation id: WBVar00675155 label: gk849843 - class: variation id: WBVar00675109 label: gk321051 - class: variation id: WBVar00675168 label: gk727803 - class: variation id: WBVar00675125 label: gk740538 - class: variation id: WBVar00675114 label: gk712086 - class: variation id: WBVar00675103 label: gk792799 - class: variation id: WBVar00675163 label: gk781196 - class: variation id: WBVar00346872 label: gk123629 - class: variation id: WBVar00675132 label: gk568173 - class: variation id: WBVar00675090 label: gk839867 - class: variation id: WBVar02151430 label: tm11080 - class: variation id: WBVar00675158 label: gk442885 - class: variation id: WBVar00675169 label: gk706398 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar00675092 label: gk450304 - class: variation id: WBVar00346901 label: gk123658 - class: variation id: WBVar00675100 label: gk864337 - class: variation id: WBVar00346871 label: gk123628 - class: variation id: WBVar00346873 label: gk123630 - class: variation id: WBVar00346879 label: gk123636 - class: variation id: WBVar00675167 label: gk908976 - class: variation id: WBVar00675138 label: gk608407 - class: variation id: WBVar00092261 label: ok990 - class: variation id: WBVar00346875 label: gk123632 - class: variation id: WBVar00675121 label: gk775133 - class: variation id: WBVar00675140 label: gk866569 - class: variation id: WBVar00675146 label: gk515803 - class: variation id: WBVar00675117 label: gk657725 - class: variation id: WBVar00675119 label: gk482821 - class: variation id: WBVar00675120 label: gk773473 - class: variation id: WBVar00346898 label: gk123655 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00675141 label: gk537988 - class: variation id: WBVar00675113 label: gk888881 - class: variation id: WBVar00346880 label: gk123637 - class: variation id: WBVar00346870 label: gk123627 - class: variation id: WBVar00675110 label: gk706396 - class: variation id: WBVar00675147 label: gk928136 - class: variation id: WBVar00675115 label: gk465526 - class: variation id: WBVar00346890 label: gk123647 - class: variation id: WBVar00675150 label: gk562165 - class: variation id: WBVar00675160 label: gk511531 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Is an ortholog of human ZDHHC18 (zinc finger DHHC-type palmitoyltransferase 18) and ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9). label: dhhc-2 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human ZDHHC18 (zinc finger DHHC-type palmitoyltransferase 18) and ZDHHC9 (zinc finger id: WBGene00012948 label: dhhc-2 other_names: - Y47H9C.2 - CELE_Y47H9C.2 - Y47H9C.2.1 - Y47H9C.2 - CE42194 taxonomy: c_elegans other_names: - Y47H9C.2 - CELE_Y47H9C.2 - Y47H9C.2.1 - Y47H9C.2 - CE42194 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00012948 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: CBG08211 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00030050 label: CBG08211 other_names: - CBG08211 - CBG_08211 - CBP07894 - CBG08211 - CBG08211.1 taxonomy: c_briggsae other_names: - CBG08211 - CBG_08211 - CBP07894 - CBG08211 - CBG08211.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00030050 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable UDP-glycosyltransferase activity. Is an ortholog of C. elegans ugt-18. label: Cbn-ugt-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ugt-18. id: WBGene00159278 label: Cbn-ugt-18 other_names: - CBN20553 - CBN20553 - CBN20553.1 - CBN20553 - CN13511 taxonomy: c_brenneri other_names: - CBN20553 - CBN20553 - CBN20553.1 - CBN20553 - CN13511 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00159278 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: Cbr-npp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00026412 label: Cbr-npp-18 other_names: - CBG03573 - CBG_03573 - CBG03573.1 - CBG03573 - CBP14769 taxonomy: c_briggsae other_names: - CBG03573 - CBG_03573 - CBG03573.1 - CBG03573 - CBP14769 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00026412 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans tsp-18. label: Cbr-tsp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tsp-18. id: WBGene00087046 label: Cbr-tsp-18 other_names: - CBG25632 - CBG_25632 - CBP44435 - CBG25632 - CBG25632.1 taxonomy: c_briggsae other_names: - CBG25632 - CBG_25632 - CBP44435 - CBG25632 - CBG25632.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00087046 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable UDP-glycosyltransferase activity. Is an ortholog of C. elegans ugt-18. label: CJA09660 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ugt-18. id: WBGene00128863 label: CJA09660 other_names: - CJA09660 - CJA09660 - CJA09660.1 - JA62225 taxonomy: c_japonica other_names: - CJA09660 - CJA09660 - CJA09660.1 - JA62225 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00128863 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: Bma-mtp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00226028 label: Bma-mtp-18 other_names: - Bm5767 - Bm1_14895A - Bm1_14895 - Bm-mtp-18 - TAG5767 - BM23308 - Bm5767 - Bm5767.1 taxonomy: b_malayi other_names: - Bm5767 - Bm1_14895A - Bm1_14895 - Bm-mtp-18 - TAG5767 - BM23308 - Bm5767 - Bm5767.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226028 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable chloride channel activity. Is an ortholog of C. elegans best-18. label: Cbn-best-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans best-18. id: WBGene00147389 label: Cbn-best-18 other_names: - CBN08664 - CN10751 - CBN08664 - CBN08664.1 taxonomy: c_brenneri other_names: - CBN08664 - CN10751 - CBN08664 - CBN08664.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00147389 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans tsp-18. label: CBN08767 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tsp-18. id: WBGene00147492 label: CBN08767 other_names: - CBN08767 - CN24513 - CBN08767.1 - CBN08767 taxonomy: c_brenneri other_names: - CBN08767 - CN24513 - CBN08767.1 - CBN08767 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00147492 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable chloride channel activity. Is an ortholog of C. elegans best-18. label: CJA35822 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans best-18. id: WBGene00211669 label: CJA35822 other_names: - CJA35822 - CJA35822c.1 - CJA35822a.1 - JA58556 - CJA35822a - CJA35822b - CJA35822c - CJA35822b.1 - JA40653 - JA39576 taxonomy: c_japonica other_names: - CJA35822 - CJA35822c.1 - CJA35822a.1 - JA58556 - CJA35822a - CJA35822b - CJA35822c - CJA35822b.1 - JA40653 - JA39576 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00211669 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18. label: SRAE_2000515300 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18. id: WBGene00265407 label: SRAE_2000515300 other_names: - SRAE_2000515300 - SR00002 - SR00024 - SRAE_2000515300 - SRP09816 - SRAE_2000515300.1 taxonomy: s_ratti other_names: - SRAE_2000515300 - SR00002 - SR00024 - SRAE_2000515300 - SRP09816 - SRAE_2000515300.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00265407 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans set-18. label: SRAE_X000209500 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans set-18. id: WBGene00267673 label: SRAE_X000209500 other_names: - SRAE_X000209500 - SRAE_X000209500.1 - SRP12141 - SRAE_X000209500 taxonomy: s_ratti other_names: - SRAE_X000209500 - SRAE_X000209500.1 - SRP12141 - SRAE_X000209500 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00267673 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-23. In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. label: Bma-mab-23 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-23. - In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination id: WBGene00222767 label: Bma-mab-23 other_names: - Bm2506 - TAG2506 - Bm-mab-23 - Bm2506a.1 - BM47998 - BM40375 - Bm2506a - Bm2506b - Bm2506b.1 taxonomy: b_malayi other_names: - Bm2506 - TAG2506 - Bm-mab-23 - Bm2506a.1 - BM47998 - BM40375 - Bm2506a - Bm2506b - Bm2506b.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00222767 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-23. In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. label: Cbn-mab-23 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-23. - In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination id: WBGene00164429 label: Cbn-mab-23 other_names: - CBN25704 - CBN25704 - CBN25704 - CBN25704.1 - CN14836 taxonomy: c_brenneri other_names: - CBN25704 - CBN25704 - CBN25704 - CBN25704.1 - CN14836 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00164429 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable sequence-specific DNA binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-23. In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination; and regulation of reproductive process. label: Cre-mab-23 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-23. - In C. elegans, mab-23 is involved in negative regulation of gene expression; neuron fate determination id: WBGene00065025 label: Cre-mab-23 other_names: - CRE12856 - cr01.sctg56.wum.15 - CRE12856.1 - RP17828 - CRE12856 taxonomy: c_remanei other_names: - CRE12856 - cr01.sctg56.wum.15 - CRE12856.1 - RP17828 - CRE12856 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00065025 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Calycin and EGF-like domain. Is an ortholog of C. elegans mab-7." label: Ppa-mab-7 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-7. id: WBGene00101001 label: Ppa-mab-7 other_names: - PPA11447 - GENEPREDICTION_SNAP300000067896 - UMM-S328-10.31 - PP64609 - PPA11447 - PPA11447.1 taxonomy: p_pacificus other_names: - PPA11447 - GENEPREDICTION_SNAP300000067896 - UMM-S328-10.31 - PP64609 - PPA11447 - PPA11447.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00101001 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Bma-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00226078 label: Bma-kin-18 other_names: - Bm5817 - Bm1_55590 - Bm1_55590A - Bm-kin-18 - TAG5817 - Bm1_21775 - Bm1_21775A - Bm1_21780A - Bm1_57415 - Bm1_21780 - Bm1_57415A - Bm5817.1 - Bm5817 - BM45429 taxonomy: b_malayi other_names: - Bm5817 - Bm1_55590 - Bm1_55590A - Bm-kin-18 - TAG5817 - Bm1_21775 - Bm1_21775A - Bm1_21780A - Bm1_57415 - Bm1_21780 - Bm1_57415A - Bm5817.1 - Bm5817 - BM45429 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226078 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Ovo-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00244785 label: Ovo-kin-18 other_names: - OVOC7976 - OVOC7976.1 - OVOC7976 - OVP00242 taxonomy: o_volvulus other_names: - OVOC7976 - OVOC7976.1 - OVOC7976 - OVP00242 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00244785 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: TMUE_2000009324 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00286054 label: TMUE_2000009324 other_names: - TMUE_2000009324 - TMUE_s0007002300 - TMUE_2000009324.4 - TMUE_2000009324.5 - TMP05371 - TMUE_2000009324.1 - TMUE_2000009324 - TMUE_2000009324.2 - TMUE_2000009324.3 taxonomy: t_muris other_names: - TMUE_2000009324 - TMUE_s0007002300 - TMUE_2000009324.4 - TMUE_2000009324.5 - TMP05371 - TMUE_2000009324.1 - TMUE_2000009324 - TMUE_2000009324.2 - TMUE_2000009324.3 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00286054 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Cbr-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00039971 label: Cbr-kin-18 other_names: - CBG21107 - CBG_21107 - CBG21107 - CBP33312 - CBG21107.1 taxonomy: c_briggsae other_names: - CBG21107 - CBG_21107 - CBG21107 - CBP33312 - CBG21107.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00039971 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Cre-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00055396 label: Cre-kin-18 other_names: - CRE03128 - cr01.sctg5.wum.119 - RP47467 - CRE03128 - CRE03128.1 taxonomy: c_remanei other_names: - CRE03128 - cr01.sctg5.wum.119 - RP47467 - CRE03128 - CRE03128.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00055396 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable interleukin-18 binding activity and interleukin-18 receptor activity. Predicted to be involved in interleukin-18-mediated signaling pathway; negative regulation of cold-induced thermogenesis; and positive regulation of cytokine production. Predicted to act upstream of or within T-helper 1 cell differentiation; natural killer cell activation; and positive regulation of NIK/NF-kappaB signaling. Predicted to be part of interleukin-18 receptor complex. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IL18R1 (interleukin 18 receptor 1); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-23 signaling pathway; cytokine mediated signaling pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil. label: Il18r1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Predicted to enable interleukin-18 binding activity and interleukin-18 receptor activity. - Predicted to be involved in interleukin-18-mediated signaling pathway; negative regulation of cold-induced - Predicted to be part of interleukin-18 receptor complex. - Orthologous to human IL18R1 (interleukin 18 receptor 1); PARTICIPATES IN interleukin-12 signaling pathway id: RGD:1308589 label: Il18r1 other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:1308589 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Cbn-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00147447 label: Cbn-kin-18 other_names: - CBN08722 - CBN08722.1 - CN27991 - CBN08722 taxonomy: c_brenneri other_names: - CBN08722 - CBN08722.1 - CN27991 - CBN08722 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00147447 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Ppa-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00104010 label: Ppa-kin-18 other_names: - PPA14456 - GENEPREDICTION_SNAP300000071198 - UMM-S112-13.21 - PPA14456 - PP73646 - PPA14456.1 taxonomy: p_pacificus other_names: - PPA14456 - GENEPREDICTION_SNAP300000071198 - UMM-S112-13.21 - PPA14456 - PP73646 - PPA14456.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00104010 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: SRAE_2000319900 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00263420 label: SRAE_2000319900 other_names: - SRAE_2000319900 - SRAE_2000319900.1 - SRP05730 - SRAE_2000319900 taxonomy: s_ratti other_names: - SRAE_2000319900 - SRAE_2000319900.1 - SRP05730 - SRAE_2000319900 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00263420 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Cbn-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00143506 label: Cbn-mab-10 other_names: - CBN04781 - CBN04781 - CN30484 - CBN04781.1 taxonomy: c_brenneri other_names: - CBN04781 - CBN04781 - CN30484 - CBN04781.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00143506 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: CBG07887 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00029793 label: CBG07887 other_names: - CBG07887 - CBG_07887 - CBG07887.1 - CBG07887 - CBP42572 taxonomy: c_briggsae other_names: - CBG07887 - CBG_07887 - CBG07887.1 - CBG07887 - CBP42572 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00029793 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: Cbn-dod-18.1 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00156839 label: Cbn-dod-18.1 other_names: - CBN18114 - CBN18114 - CBN18114.1 - CN05630 taxonomy: c_brenneri other_names: - CBN18114 - CBN18114 - CBN18114.1 - CN05630 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00156839 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans ztf-18. label: Cbr-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00035500 label: Cbr-ztf-18 other_names: - CBG15176 - CBG_15176 - CBP18319 - CBG15176.1 - CBG15176 taxonomy: c_briggsae other_names: - CBG15176 - CBG_15176 - CBP18319 - CBG15176.1 - CBG15176 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00035500 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: Cre-dod-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00070021 label: Cre-dod-18 other_names: - CRE09674 - cr01.sctg168.wum.21 - RP28038 - CRE09674.1 - CRE09674 taxonomy: c_remanei other_names: - CRE09674 - cr01.sctg168.wum.21 - RP28038 - CRE09674.1 - CRE09674 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00070021 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: OVOC11132 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00247941 label: OVOC11132 other_names: - OVOC11132 - OVP11192 - OVOC11132 - OVOC11132.1 taxonomy: o_volvulus other_names: - OVOC11132 - OVP11192 - OVOC11132 - OVOC11132.1 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00247941 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: TMUE_2000007219 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00288342 label: TMUE_2000007219 other_names: - TMUE_2000007219 - TMUE_s0026005900 - TMUE_2000007219.2 - TMUE_2000007219 - TMUE_2000007219.1 - TMP06357 taxonomy: t_muris other_names: - TMUE_2000007219 - TMUE_s0026005900 - TMUE_2000007219.2 - TMUE_2000007219 - TMUE_2000007219.1 - TMP06357 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00288342 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: Bm6585 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00226846 label: Bm6585 other_names: - Bm6585 - Bm1_02020 - TAG6585 - Bm1_02020A - Bm6585.1 - BM03135 - Bm6585 taxonomy: b_malayi other_names: - Bm6585 - Bm1_02020 - TAG6585 - Bm1_02020A - Bm6585.1 - BM03135 - Bm6585 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226846 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: Cbn-dod-18.2 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00140301 label: Cbn-dod-18.2 other_names: - CBN01576 - CBN01576 - CN05631 - CBN01576.1 taxonomy: c_brenneri other_names: - CBN01576 - CBN01576 - CN05631 - CBN01576.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00140301 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: CJA17311 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00136515 label: CJA17311 other_names: - CJA17311 - JA07404 - CJA17311.1 - CJA17311 taxonomy: c_japonica other_names: - CJA17311 - JA07404 - CJA17311.1 - CJA17311 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00136515 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in RNA splicing. Is an ortholog of C. elegans prp-18. label: Cjp-prp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans prp-18. id: WBGene00207561 label: Cjp-prp-18 other_names: - CJA31714 - CJA31714 - CJA31714.1 - JA49135 taxonomy: c_japonica other_names: - CJA31714 - CJA31714 - CJA31714.1 - JA49135 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00207561 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: Cjp-ttr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00130070 label: Cjp-ttr-18 other_names: - CJA10866 - JA17186 - CJA10866 - CJA10866.1 taxonomy: c_japonica other_names: - CJA10866 - JA17186 - CJA10866 - CJA10866.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00130070 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans ztf-18. label: Cre-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00063474 label: Cre-ztf-18 other_names: - CRE03007 - cr01.sctg39.wum.65 - CRE03007 - RP25454 - CRE03007.1 taxonomy: c_remanei other_names: - CRE03007 - cr01.sctg39.wum.65 - CRE03007 - RP25454 - CRE03007.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00063474 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: SRAE_1000208700 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00258699 label: SRAE_1000208700 other_names: - SRAE_1000208700 - SRAE_1000208700 - SRAE_1000208700.1 - SRP07780 taxonomy: s_ratti other_names: - SRAE_1000208700 - SRAE_1000208700 - SRAE_1000208700.1 - SRP07780 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00258699 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans ztf-18. label: Bma-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00226244 label: Bma-ztf-18 other_names: - Bm5983 - Bm-ztf-18 - Bm1_04595 - Bm1_04595A - TAG5983 - Bm5983.1 - Bm5983 - BM34445 taxonomy: b_malayi other_names: - Bm5983 - Bm-ztf-18 - Bm1_04595 - Bm1_04595A - TAG5983 - Bm5983.1 - Bm5983 - BM34445 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226244 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans ztf-18. label: Cbn-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00156236 label: Cbn-ztf-18 other_names: - CBN17511 - CBN17511.1 - CBN17511 - CN28264 taxonomy: c_brenneri other_names: - CBN17511 - CBN17511.1 - CBN17511 - CN28264 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00156236 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: CBN08558 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00147283 label: CBN08558 other_names: - CBN08558 - CBN08558.1 - CBN08558 - CN04932 taxonomy: c_brenneri other_names: - CBN08558 - CBN08558.1 - CBN08558 - CN04932 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00147283 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: Ppa-dod-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00273487 label: Ppa-dod-18 other_names: - PPA35118 - PPA35118 - PP57783 - PPA35118.1 taxonomy: p_pacificus other_names: - PPA35118 - PPA35118 - PP57783 - PPA35118.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00273487 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: PPA28104 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00117658 label: PPA28104 other_names: - PPA28104 - UMM-S10-71.12 - GENEPREDICTION_SNAP300000086521 - PP36504 - PPA28104.1 - PPA28104 taxonomy: p_pacificus other_names: - PPA28104 - UMM-S10-71.12 - GENEPREDICTION_SNAP300000086521 - PP36504 - PPA28104.1 - PPA28104 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00117658 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans kin-18. In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal pumping. label: Cjp-kin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans kin-18. - In C. elegans, kin-18 is involved in feeding behavior; regulation of meiosis I; and regulation of pharyngeal id: WBGene00127702 label: Cjp-kin-18 other_names: - CJA08497 - JA43561 - CJA08497 - CJA08497.1 taxonomy: c_japonica other_names: - CJA08497 - JA43561 - CJA08497 - CJA08497.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00127702 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: Cbn-ttr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00160301 label: Cbn-ttr-18 other_names: - CBN21576 - CBN21576 - CN08238 - CBN21576.1 - CBN21576 taxonomy: c_brenneri other_names: - CBN21576 - CBN21576 - CN08238 - CBN21576.1 - CBN21576 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00160301 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: Cbr-dod-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00030049 label: Cbr-dod-18 other_names: - CBG08210 - CBG_08210 - CBG08210.1 - CBP34715 - CBG08210 taxonomy: c_briggsae other_names: - CBG08210 - CBG_08210 - CBG08210.1 - CBP34715 - CBG08210 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00030049 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans ztf-18. label: Cjp-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00131753 label: Cjp-ztf-18 other_names: - CJA12549 - CJA12549a.1 - CJA12549a - CJA12549b.1 - JA59980 - CJA12549b - JA41602 taxonomy: c_japonica other_names: - CJA12549 - CJA12549a.1 - CJA12549a - CJA12549b.1 - JA59980 - CJA12549b - JA41602 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00131753 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: Cre-ttr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00053580 label: Cre-ttr-18 other_names: - CRE01741 - cr01.sctg2.wum.364 - RP08732 - CRE01741.1 - CRE01741 taxonomy: c_remanei other_names: - CRE01741 - cr01.sctg2.wum.364 - RP08732 - CRE01741.1 - CRE01741 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00053580 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans ztf-18. label: Ovo-ztf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ztf-18. id: WBGene00243093 label: Ovo-ztf-18 other_names: - OVOC6284 - OVP06937 - OVOC6284.1 - OVOC6284 taxonomy: o_volvulus other_names: - OVOC6284 - OVP06937 - OVOC6284.1 - OVOC6284 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00243093 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: Ppa-ttr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00094267 label: Ppa-ttr-18 other_names: - PPA04713 - UMM-S273-1.10 - GENEPREDICTION_SNAP300000061131 - PP08958 - PPA04713 - PPA04713.1 taxonomy: p_pacificus other_names: - PPA04713 - UMM-S273-1.10 - GENEPREDICTION_SNAP300000061131 - PP08958 - PPA04713 - PPA04713.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00094267 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: PPA04714 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00094268 label: PPA04714 other_names: - PPA04714 - GENEPREDICTION_SNAP300000061132 - UMM-S273-1.29 - PPA04714 - PPA04714.1 - PP44815 taxonomy: p_pacificus other_names: - PPA04714 - GENEPREDICTION_SNAP300000061132 - UMM-S273-1.29 - PPA04714 - PPA04714.1 - PP44815 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00094268 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: PPA25969 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00115523 label: PPA25969 other_names: - PPA25969 - GENEPREDICTION_SNAP300000086654 - GENEPREDICTION_SNAP300000082821 - GENEPREDICTION_SNAP300000086656 - UMM-S10-77.32 - PPA25969.1 - PPA25969 - PP68637 taxonomy: p_pacificus other_names: - PPA25969 - GENEPREDICTION_SNAP300000086654 - GENEPREDICTION_SNAP300000082821 - GENEPREDICTION_SNAP300000086656 - UMM-S10-77.32 - PPA25969.1 - PPA25969 - PP68637 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00115523 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: PPA30825 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00203691 label: PPA30825 other_names: - PPA30825 - UMM-S7-12.37 - PPA30825.1 - PPA30825 - PP73200 taxonomy: p_pacificus other_names: - PPA30825 - UMM-S7-12.37 - PPA30825.1 - PPA30825 - PP73200 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00203691 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Ovo-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00247437 label: Ovo-mab-10 other_names: - OVOC10628 - OVOC10628 - OVP07338 - OVOC10628.1 taxonomy: o_volvulus other_names: - OVOC10628 - OVOC10628 - OVP07338 - OVOC10628.1 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00247437 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: TMUE_1000003090 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00292769 label: TMUE_1000003090 other_names: - TMUE_1000003090 - TMUE_s0113000100 - TMP08771 - TMUE_1000003090 - TMUE_1000003090.1 taxonomy: t_muris other_names: - TMUE_1000003090 - TMUE_s0113000100 - TMP08771 - TMUE_1000003090 - TMUE_1000003090.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00292769 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Bma-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00225701 label: Bma-mab-10 other_names: - Bm5440 - Bm1_56365 - TAG5440 - Bm1_57325 - Bm1_57325A - Bm1_56365A - Bm-mab-10 - BM46356 - Bm5440 - Bm5440.1 taxonomy: b_malayi other_names: - Bm5440 - Bm1_56365 - TAG5440 - Bm1_57325 - Bm1_57325A - Bm1_56365A - Bm-mab-10 - BM46356 - Bm5440 - Bm5440.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00225701 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Cbr-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00026014 label: Cbr-mab-10 other_names: - CBG03078 - CBG_03078 - CBP49400 - CBG03078 - CBG03078.1 taxonomy: c_briggsae other_names: - CBG03078 - CBG_03078 - CBP49400 - CBG03078 - CBG03078.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00026014 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Cre-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00053391 label: Cre-mab-10 other_names: - CRE02223 - cr01.sctg2.wum.179 - CRE02223.1 - RP39277 - CRE02223 taxonomy: c_remanei other_names: - CRE02223 - cr01.sctg2.wum.179 - CRE02223.1 - RP39277 - CRE02223 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00053391 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Ppa-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00099664 label: Ppa-mab-10 other_names: - PPA10110 - UMM-S296-10.76 - GENEPREDICTION_SNAP300000067157 - PPA10110 - PPA10110.1 - PP59651 taxonomy: p_pacificus other_names: - PPA10110 - UMM-S296-10.76 - GENEPREDICTION_SNAP300000067157 - PPA10110 - PPA10110.1 - PP59651 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00099664 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is affected by Cbr-spr-4 based on RNA-seq studies. Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and Mitochondrial 18kDa protein. Is an ortholog of C. elegans mtp-18." label: CBG28141 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Mitochondrial 18 KDa protein (MTP18) and" - Is an ortholog of C. elegans mtp-18. id: WBGene00164982 label: CBG28141 other_names: - CBG28141 - CBG_28141 - CBG28141 - CBP44102 - CBG28141.1 taxonomy: c_briggsae other_names: - CBG28141 - CBG_28141 - CBG28141 - CBP44102 - CBG28141.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00164982 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in nucleus. Is an ortholog of C. elegans mab-10. In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development, heterochronic; and regulation of vulval development. label: Cjp-mab-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans mab-10. - In C. elegans, mab-10 is involved in several processes, including exit from mitosis; regulation of development id: WBGene00131621 label: Cjp-mab-10 other_names: - CJA12417 - JA54043 - CJA12417 - CJA12417.1 taxonomy: c_japonica other_names: - CJA12417 - JA54043 - CJA12417 - CJA12417.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00131621 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: Bma-dod-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00223198 label: Bma-dod-18 other_names: - Bm2937 - Bm-dod-18 - TAG2937 - Bm1_26810 - Bm1_26810A - BM47933 - Bm2937a.1 - Bm2937a - Bm2937b - BM48173 - Bm2937b.1 taxonomy: b_malayi other_names: - Bm2937 - Bm-dod-18 - TAG2937 - Bm1_26810 - Bm1_26810A - BM47933 - Bm2937a.1 - Bm2937a - Bm2937b - BM48173 - Bm2937b.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00223198 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in cell surface. Is an ortholog of C. elegans ttr-18. label: Cbr-ttr-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ttr-18. id: WBGene00025847 label: Cbr-ttr-18 other_names: - CBG02878 - CBG_02878 - CBG02878.1 - CBP00868 - CBG02878 taxonomy: c_briggsae other_names: - CBG02878 - CBG_02878 - CBG02878.1 - CBP00868 - CBG02878 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00025847 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleic acid binding activity. Is an ortholog of C. elegans Y46G5A.18. label: CRE24584 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y46G5A.18. id: WBGene00059565 label: CRE24584 other_names: - CRE24584 - cr01.sctg15.wum.11 - CRE24584.1 - CRE24584 - RP46117 taxonomy: c_remanei other_names: - CRE24584 - cr01.sctg15.wum.11 - CRE24584.1 - CRE24584 - RP46117 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00059565 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable nucleoside triphosphate diphosphatase activity. Is an ortholog of C. elegans dod-18. label: OVOC13398 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans dod-18. id: WBGene00255405 label: OVOC13398 other_names: - OVOC13398 - OVOC13398 - OVOC13398.1 - OVP13211 taxonomy: o_volvulus other_names: - OVOC13398 - OVOC13398 - OVOC13398.1 - OVP13211 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00255405 - allele: - class: variation id: WBVar01060000 label: gk549901 - class: variation id: WBVar01060066 label: gk554356 - class: variation id: WBVar01059994 label: gk760243 - class: variation id: WBVar01059981 label: gk895250 - class: variation id: WBVar01060085 label: gk832363 - class: variation id: WBVar01060018 label: gk529872 - class: variation id: WBVar01060049 label: gk478156 - class: variation id: WBVar00474455 label: gk251212 - class: variation id: WBVar01060064 label: gk812650 - class: variation id: WBVar01060043 label: gk459551 - class: variation id: WBVar01060059 label: gk591192 - class: variation id: WBVar00474440 label: gk251197 - class: variation id: WBVar01060032 label: gk530345 - class: variation id: WBVar01059983 label: gk730410 - class: variation id: WBVar00474437 label: gk251194 - class: variation id: WBVar01060002 label: gk625442 - class: variation id: WBVar01060023 label: gk760798 - class: variation id: WBVar01059998 label: gk765929 - class: variation id: WBVar01059991 label: gk731065 - class: variation id: WBVar01060021 label: gk833039 - class: variation id: WBVar01060029 label: gk382118 - class: variation id: WBVar01060083 label: gk869929 - class: variation id: WBVar01060025 label: gk537006 - class: variation id: WBVar00261705 label: ttTi34392 - class: variation id: WBVar00146282 label: gk1131 - class: variation id: WBVar01060030 label: gk460609 - class: variation id: WBVar00474443 label: gk251200 - class: variation id: WBVar00474445 label: gk251202 - class: variation id: WBVar01060065 label: gk933948 - class: variation id: WBVar01060087 label: gk834567 - class: variation id: WBVar01496882 label: gk961145 - class: variation id: WBVar01060071 label: gk377825 - class: variation id: WBVar01060070 label: gk935732 - class: variation id: WBVar00262230 label: ttTI35718 - class: variation id: WBVar01059985 label: gk469984 - class: variation id: WBVar01060082 label: gk697247 - class: variation id: WBVar01060017 label: gk720860 - class: variation id: WBVar01060010 label: gk810415 - class: variation id: WBVar00094398 label: ok3378 - class: variation id: WBVar01060042 label: gk878810 - class: variation id: WBVar01060037 label: gk925039 - class: variation id: WBVar01060067 label: gk327075 - class: variation id: WBVar01060031 label: gk891905 - class: variation id: WBVar02137387 label: h10675 - class: variation id: WBVar01059984 label: gk903261 - class: variation id: WBVar01060015 label: gk537004 - class: variation id: WBVar01484859 label: gk949119 - class: variation id: WBVar00474450 label: gk251207 - class: variation id: WBVar01060011 label: gk709070 - class: variation id: WBVar00474441 label: gk251198 - class: variation id: WBVar01060038 label: gk622619 - class: variation id: WBVar01060046 label: gk775533 - class: variation id: WBVar01060012 label: gk586650 - class: variation id: WBVar01059992 label: gk809281 - class: variation id: WBVar01060020 label: gk467852 - class: variation id: WBVar02137386 label: h3445 - class: variation id: WBVar01060016 label: gk678080 - class: variation id: WBVar01060048 label: gk567944 - class: variation id: WBVar01500213 label: gk964459 - class: variation id: WBVar02151838 label: tm11509 - class: variation id: WBVar00474447 label: gk251204 - class: variation id: WBVar01060069 label: gk789273 - class: variation id: WBVar01060075 label: gk500782 - class: variation id: WBVar01060008 label: gk624441 - class: variation id: WBVar00474439 label: gk251196 - class: variation id: WBVar01060079 label: gk814230 - class: variation id: WBVar00474456 label: gk251213 - class: variation id: WBVar01499299 label: gk963271 - class: variation id: WBVar01060036 label: gk617958 - class: variation id: WBVar01060060 label: gk497279 - class: variation id: WBVar01060041 label: gk684601 - class: variation id: WBVar00474454 label: gk251211 - class: variation id: WBVar00296443 label: tm4860 - class: variation id: WBVar01060078 label: gk639964 - class: variation id: WBVar01499316 label: gk963301 - class: variation id: WBVar01059988 label: gk387611 - class: variation id: WBVar01493058 label: gk957321 - class: variation id: WBVar01060022 label: gk637841 - class: variation id: WBVar01060068 label: gk561388 - class: variation id: WBVar01060045 label: gk324781 - class: variation id: WBVar01060052 label: gk521275 - class: variation id: WBVar01060035 label: gk761687 - class: variation id: WBVar00474448 label: gk251205 - class: variation id: WBVar01060044 label: gk366486 - class: variation id: WBVar01059995 label: gk879897 - class: variation id: WBVar00474442 label: gk251199 - class: variation id: WBVar01060073 label: gk655445 - class: variation id: WBVar01060062 label: gk825484 - class: variation id: WBVar01060033 label: gk825483 - class: variation id: WBVar00278350 label: gk1132 - class: variation id: WBVar01060019 label: gk609887 - class: variation id: WBVar01060063 label: gk928655 - class: variation id: WBVar01060053 label: gk542691 - class: variation id: WBVar00474444 label: gk251201 - class: variation id: WBVar00531859 label: gk1125 - class: variation id: WBVar01060007 label: gk658889 - class: variation id: WBVar01060028 label: gk873654 - class: variation id: WBVar01060076 label: gk442610 - class: variation id: WBVar01060080 label: gk871093 - class: variation id: WBVar01060056 label: gk553454 - class: variation id: WBVar01060047 label: gk336197 - class: variation id: WBVar01059993 label: gk772651 - class: variation id: WBVar01060077 label: gk776640 - class: variation id: WBVar00474452 label: gk251209 - class: variation id: WBVar01059997 label: gk744303 - class: variation id: WBVar01060058 label: gk384113 - class: variation id: WBVar01060039 label: gk806200 - class: variation id: WBVar01060027 label: gk817057 - class: variation id: WBVar01059989 label: gk595707 - class: variation id: WBVar00145920 label: gk552 - class: variation id: WBVar01500212 label: gk964458 - class: variation id: WBVar01060024 label: gk537005 - class: variation id: WBVar01060006 label: gk673049 - class: variation id: WBVar01060054 label: gk566243 - class: variation id: WBVar01060051 label: gk642916 - class: variation id: WBVar01060086 label: gk652074 - class: variation id: WBVar00474438 label: gk251195 - class: variation id: WBVar01060004 label: gk454524 - class: variation id: WBVar01059990 label: gk321326 - class: variation id: WBVar01060074 label: gk710680 - class: variation id: WBVar00474451 label: gk251208 - class: variation id: WBVar01059999 label: gk313335 - class: variation id: WBVar01060057 label: gk798808 - class: variation id: WBVar01059996 label: gk354983 - class: variation id: WBVar01060001 label: gk753296 - class: variation id: WBVar01060040 label: gk642370 - class: variation id: WBVar01060072 label: gk488309 - class: variation id: WBVar01060061 label: gk558438 - class: variation id: WBVar01059987 label: gk365773 - class: variation id: WBVar01059986 label: gk612621 - class: variation id: WBVar00474446 label: gk251203 - class: variation id: WBVar00278354 label: gk1133 - class: variation id: WBVar01059982 label: gk900113 - class: variation id: WBVar01498809 label: gk964462 - class: variation id: WBVar00261443 label: ttTi33641 - class: variation id: WBVar01060003 label: gk566242 - class: variation id: WBVar00092917 label: ok1712 - class: variation id: WBVar01499621 label: gk963706 - class: variation id: WBVar01060026 label: gk537007 - class: variation id: WBVar01060088 label: gk822325 - class: variation id: WBVar00262583 label: ttTi36569 - class: variation id: WBVar01060013 label: gk522491 - class: variation id: WBVar01060034 label: gk818884 - class: variation id: WBVar00474453 label: gk251210 - class: variation id: WBVar01060014 label: gk538629 - class: variation id: WBVar01060055 label: gk909185 - class: variation id: WBVar01060084 label: gk859671 - class: variation id: WBVar00474449 label: gk251206 - class: variation id: WBVar01060081 label: gk675437 - class: variation id: WBVar01060005 label: gk469985 - class: variation id: WBVar01060009 label: gk325964 - class: variation id: WBVar01060050 label: gk450954 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including male anatomical structure morphogenesis; mechanosensory behavior; and negative regulation of synapse pruning. Predicted to be located in nucleus. Expressed in several structures, including AVG; body wall musculature; head neurons; intestine; and vulval muscle. Is an ortholog of human DMRT1 (doublesex and mab-3 related transcription factor 1) and DMRTC2 (DMRT like family C2). label: dmd-10 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of human DMRT1 (doublesex and mab-3 related transcription factor 1) and DMRTC2 (DMRT like id: WBGene00007929 label: dmd-10 other_names: - C34D1.1 - CELE_C34D1.1 - dmd-11 - C34D1.1.1 - C34D1.1 - CE54228 taxonomy: c_elegans other_names: - C34D1.1 - CELE_C34D1.1 - dmd-11 - C34D1.1.1 - C34D1.1 - CE54228 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00007929 - allele: - class: variation id: WBVar02129155 label: h18175 - class: variation id: WBVar01498889 label: gk962611 - class: variation id: WBVar00695666 label: gk724694 - class: variation id: WBVar00695680 label: gk343399 - class: variation id: WBVar01498978 label: gk962738 - class: variation id: WBVar00695679 label: gk906569 - class: variation id: WBVar01499569 label: gk963640 - class: variation id: WBVar01476747 label: gk941004 - class: variation id: WBVar00695676 label: gk347260 - class: variation id: WBVar00319658 label: snx2086 - class: variation id: WBVar00695659 label: gk607527 - class: variation id: WBVar00695677 label: gk433707 - class: variation id: WBVar00253661 label: ttTi2215 - class: variation id: WBVar00353801 label: gk130558 - class: variation id: WBVar00353800 label: gk130557 - class: variation id: WBVar01499823 label: gk963947 - class: variation id: WBVar00695665 label: gk451884 - class: variation id: WBVar00695663 label: gk458488 - class: variation id: WBVar00695658 label: gk393577 - class: variation id: WBVar01499999 label: gk964175 - class: variation id: WBVar01499889 label: gk964031 - class: variation id: WBVar01495546 label: gk959809 - class: variation id: WBVar00353799 label: gk130556 - class: variation id: WBVar00695672 label: gk735146 - class: variation id: WBVar00695657 label: gk898539 - class: variation id: WBVar01499058 label: gk962862 - class: variation id: WBVar00695671 label: gk523865 - class: variation id: WBVar00353802 label: gk130559 - class: variation id: WBVar01500050 label: gk964241 - class: variation id: WBVar01498534 label: gk963270 - class: variation id: WBVar01499739 label: gk963849 - class: variation id: WBVar00695654 label: gk748695 - class: variation id: WBVar00695664 label: gk380922 - class: variation id: WBVar00695678 label: gk406136 - class: variation id: WBVar00695660 label: gk537999 - class: variation id: WBVar00695656 label: gk932479 - class: variation id: WBVar01498890 label: gk962612 - class: variation id: WBVar00695655 label: gk367962 - class: variation id: WBVar00695662 label: gk671660 - class: variation id: WBVar01499908 label: gk964059 - class: variation id: WBVar00321489 label: snx3917 - class: variation id: WBVar00695674 label: gk424387 - class: variation id: WBVar00695668 label: gk808516 - class: variation id: WBVar00353797 label: gk130554 - class: variation id: WBVar00695669 label: gk325096 - class: variation id: WBVar00695670 label: gk889965 - class: variation id: WBVar01498979 label: gk962739 - class: variation id: WBVar01500181 label: gk964417 - class: variation id: WBVar00695661 label: gk639069 - class: variation id: WBVar00695673 label: gk870166 - class: variation id: WBVar00353798 label: gk130555 - class: variation id: WBVar01498939 label: gk962681 - class: variation id: WBVar01476748 label: gk941005 - class: variation id: WBVar00695675 label: gk456604 - class: variation id: WBVar00695667 label: gk553075 - class: variation id: WBVar02151455 label: tm11106 - class: variation id: WBVar00317790 label: snx218 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable metal ion binding activity. Predicted to be located in nucleus. Expressed in hypodermis. label: set-10 legacy_description: set-10 encodes a divergent ortholog of human SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-10 is paralogous to SET-14, SET-18, and SET-30; SET-10 has no obvious function in individual RNAi assays of vulval development, or in mass RNAi assays. merged_into: ~ name: class: gene highlight: description_all: - SMYD1 (OMIM:606846), SMYD2 (OMIM:610663), and SYMD3 (OMIM:608783); SET-10 is paralogous to SET-14, SET-18 id: WBGene00009370 label: set-10 other_names: - F33H2.7 - CELE_F33H2.7 - CE34302 - F33H2.7 - F33H2.7.1 - F33H2.7.2 taxonomy: c_elegans other_names: - F33H2.7 - CELE_F33H2.7 - CE34302 - F33H2.7 - F33H2.7.1 - F33H2.7.2 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00009370 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Is an ortholog of C. elegans vps-18. In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. label: Cbn-vps-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans vps-18. - In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in id: WBGene00155013 label: Cbn-vps-18 other_names: - CBN16288 - CBN16288.1 - CN02029 - CBN16288 taxonomy: c_brenneri other_names: - CBN16288 - CBN16288.1 - CN02029 - CBN16288 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00155013 - allele: - class: variation id: WBVar01499663 label: gk963756 - class: variation id: WBVar02150845 label: tm4474 - class: variation id: WBVar00761192 label: gk612918 - class: variation id: WBVar00095038 label: oy40 - class: variation id: WBVar00761195 label: gk361441 - class: variation id: WBVar00761186 label: gk544342 - class: variation id: WBVar00761188 label: gk444433 - class: variation id: WBVar00761187 label: gk932983 - class: variation id: WBVar00761180 label: gk853479 - class: variation id: WBVar00761185 label: gk767977 - class: variation id: WBVar00761193 label: gk446683 - class: variation id: WBVar00761189 label: gk425466 - class: variation id: WBVar00761190 label: gk405038 - class: variation id: WBVar00375675 label: gk152432 - class: variation id: WBVar01499702 label: gk963801 - class: variation id: WBVar00761184 label: gk322215 - class: variation id: WBVar00761194 label: gk901074 - class: variation id: WBVar00761177 label: gk788440 - class: variation id: WBVar00091586 label: ok288 - class: variation id: WBVar00089237 label: mu220 - class: variation id: WBVar01498435 label: gk963053 - class: variation id: WBVar00761191 label: gk505952 - class: variation id: WBVar00761183 label: gk851026 - class: variation id: WBVar00761178 label: gk321110 - class: variation id: WBVar01498940 label: gk962682 - class: variation id: WBVar00761181 label: gk882464 - class: variation id: WBVar00375674 label: gk152431 - class: variation id: WBVar00761182 label: gk474107 - class: variation id: WBVar00145296 label: ez11 - class: variation id: WBVar01499662 label: gk963755 - class: variation id: WBVar00761179 label: gk768999 - class: variation id: WBVar00145294 label: ez6 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including epidermal cell fate specification; negative regulation of transcription by RNA polymerase II; and nematode male tail tip morphogenesis. Located in nucleus. Expressed in several structures, including E lineage cell; embryonic cell; intestine; mc3V; and pharyngeal cell. Is an ortholog of human HES5 (hes family bHLH transcription factor 5). label: ref-1 legacy_description: ref-1 encodes a protein with two basic helix-loop-helix (bHLH) domains that is distantly related to the hairy/Enhancer of split subfamily of bHLH transcription factors; REF-1 is required in hermaphrodites during early larval development for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB-5 homeodomain protein activity; REF-1 is also required for head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB-3 transcriptional repression which in turn, promotes expression of LIN-32, a proneural bHLH transcription factor. merged_into: ~ name: class: gene highlight: description_all: - for regulating the pattern of posterior Pn.p hypodermal cell fusions, primarily through regulation of MAB - head morphogenesis and specification of the V6 lateral seam cell fate; in males, ref-1 is a target of MAB id: WBGene00004334 label: ref-1 other_names: - T01E8.2 - hlh-24 - CELE_T01E8.2 - T01E8.2 - CE02306 - T01E8.2.1 taxonomy: c_elegans other_names: - T01E8.2 - hlh-24 - CELE_T01E8.2 - T01E8.2 - CE02306 - T01E8.2.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00004334 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Is an ortholog of C. elegans vps-18. In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. label: Cbr-vps-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans vps-18. - In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in id: WBGene00034243 label: Cbr-vps-18 other_names: - CBG13485 - CBG_13485 - CBG13485.1 - CBP41902 - CBG13485.2 - CBG13485 taxonomy: c_briggsae other_names: - CBG13485 - CBG_13485 - CBG13485.1 - CBP41902 - CBG13485.2 - CBG13485 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00034243 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Is an ortholog of C. elegans vps-18. In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. label: Cjp-vps-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans vps-18. - In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in id: WBGene00129326 label: Cjp-vps-18 other_names: - CJA10122 - JA67250 - CJA10122 - CJA10122.1 taxonomy: c_japonica other_names: - CJA10122 - JA67250 - CJA10122 - CJA10122.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00129326 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in intracellular protein transport and vesicle-mediated transport. Is an ortholog of C. elegans vps-18. In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance. label: Cre-vps-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans vps-18. - In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in id: WBGene00065127 label: Cre-vps-18 other_names: - CRE17349 - cr01.sctg57.wum.35 - RP36498 - CRE17349.1 - CRE17349 taxonomy: c_remanei other_names: - CRE17349 - cr01.sctg57.wum.35 - RP36498 - CRE17349.1 - CRE17349 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00065127 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity and protein kinase activity. Expressed in AFDL and AFDR. Is an ortholog of C. elegans gcy-18. In C. elegans, gcy-18 is involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis. label: Cbn-gcy-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans gcy-18. - In C. elegans, gcy-18 is involved in detection of temperature stimulus; thermosensory behavior; and thermotaxis id: WBGene00151174 label: Cbn-gcy-18 other_names: - CBN12449 - CN38108 - CBN12449.1 - CBN12449 taxonomy: c_brenneri other_names: - CBN12449 - CN38108 - CBN12449.1 - CBN12449 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00151174 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: Bm6308 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00226569 label: Bm6308 other_names: - Bm6308 - TAG6308 - Bm1_24090 - Bm1_24090A - BM44063 - Bm6308 - Bm6308.1 taxonomy: b_malayi other_names: - Bm6308 - TAG6308 - Bm1_24090 - Bm1_24090A - BM44063 - Bm6308 - Bm6308.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226569 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: Bm6652 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00226913 label: Bm6652 other_names: - Bm6652 - Bm1_41750A - Bm1_41750 - TAG6652 - Bm6652a - BM00647 - Bm6652b - Bm6652b.1 - Bm6652a.1 - BM48516 taxonomy: b_malayi other_names: - Bm6652 - Bm1_41750A - Bm1_41750 - TAG6652 - Bm6652a - BM00647 - Bm6652b - Bm6652b.1 - Bm6652a.1 - BM48516 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226913 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans acl-9 and bus-18. label: Bma-bus-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans acl-9 and bus-18. id: WBGene00228263 label: Bma-bus-18 other_names: - Bm8002 - Bm1_04260A - TAG8002 - Bm-bus-18 - Bm1_04260 - Bm8002.1 - Bm8002 - BM42905 taxonomy: b_malayi other_names: - Bm8002 - Bm1_04260A - TAG8002 - Bm-bus-18 - Bm1_04260 - Bm8002.1 - Bm8002 - BM42905 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00228263 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: CJA05418 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00124622 label: CJA05418 other_names: - CJA05418 - CJA05418 - CJA05418.1 - JA03474 taxonomy: c_japonica other_names: - CJA05418 - CJA05418 - CJA05418.1 - JA03474 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00124622 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: CJA06822 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00126026 label: CJA06822 other_names: - CJA06822 - JA15839 - CJA06822.1 - CJA06822 taxonomy: c_japonica other_names: - CJA06822 - JA15839 - CJA06822.1 - CJA06822 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00126026 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: CRE26368 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00054423 label: CRE26368 other_names: - CRE26368 - cr01.sctg3.wum.423 - RP44542 - CRE26368.1 - CRE26368 taxonomy: c_remanei other_names: - CRE26368 - cr01.sctg3.wum.423 - RP44542 - CRE26368.1 - CRE26368 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00054423 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: SRAE_2000005800 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00260247 label: SRAE_2000005800 other_names: - SRAE_2000005800 - SR04500 - SR03303 - SRAE_2000005800.1 - SRP02802 - SRAE_2000005800 taxonomy: s_ratti other_names: - SRAE_2000005800 - SR04500 - SR03303 - SRAE_2000005800.1 - SRP02802 - SRAE_2000005800 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00260247 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: SRAE_2000071100 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00260909 label: SRAE_2000071100 other_names: - SRAE_2000071100 - SR03064 - SRP12050 - SRAE_2000071100 - SRAE_2000071100.1 taxonomy: s_ratti other_names: - SRAE_2000071100 - SR03064 - SRP12050 - SRAE_2000071100 - SRAE_2000071100.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00260909 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: Bm6623 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00226884 label: Bm6623 other_names: - Bm6623 - Bm1_17190A - TAG6623 - Bm1_17190 - Bm6623.1 - Bm6623 - BM00499 taxonomy: b_malayi other_names: - Bm6623 - Bm1_17190A - TAG6623 - Bm1_17190 - Bm6623.1 - Bm6623 - BM00499 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00226884 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable acyltransferase activity. Is an ortholog of C. elegans acl-9 and bus-18. label: Bma-acl-9 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans acl-9 and bus-18. id: WBGene00233858 label: Bma-acl-9 other_names: - Bm13597 - Bm-acl-9 - TAG13597 - Bm13597.1 - BM40423 - Bm13597 taxonomy: b_malayi other_names: - Bm13597 - Bm-acl-9 - TAG13597 - Bm13597.1 - BM40423 - Bm13597 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00233858 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: CBG14940 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00035314 label: CBG14940 other_names: - CBG14940 - CBG_14940 - CBP44913 - CBG14940 - CBG14940.1 taxonomy: c_briggsae other_names: - CBG14940 - CBG_14940 - CBP44913 - CBG14940 - CBG14940.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00035314 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: CBN02669 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00141394 label: CBN02669 other_names: - CBN02669 - CBN02669.1 - CBN02669 - CN27777 taxonomy: c_brenneri other_names: - CBN02669 - CBN02669.1 - CBN02669 - CN27777 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00141394 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: CBN14142 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00152867 label: CBN14142 other_names: - CBN14142 - CN06337 - CBN14142.1 - CBN14142 taxonomy: c_brenneri other_names: - CBN14142 - CN06337 - CBN14142.1 - CBN14142 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00152867 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans metl-18. label: Cbr-metl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans metl-18. id: WBGene00031383 label: Cbr-metl-18 other_names: - CBG09867 - CBG_09867 - CBG09867.1 - CBG09867 - CBP16665 taxonomy: c_briggsae other_names: - CBG09867 - CBG_09867 - CBG09867.1 - CBG09867 - CBP16665 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00031383 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans metl-18. label: CJA16153 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans metl-18. id: WBGene00135357 label: CJA16153 other_names: - CJA16153 - CJA16153 - CJA16153.1 - JA44178 taxonomy: c_japonica other_names: - CJA16153 - CJA16153 - CJA16153.1 - JA44178 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00135357 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: CJA17997 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00137201 label: CJA17997 other_names: - CJA17997 - CJA17997.1 - JA36211 - CJA17997 taxonomy: c_japonica other_names: - CJA17997 - CJA17997.1 - JA36211 - CJA17997 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00137201 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA03947 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00093501 label: PPA03947 other_names: - PPA03947 - GENEPREDICTION_SNAP300000060367 - UMM-S7-6.31 - PPA03947.1 - PP73670 - PPA03947 taxonomy: p_pacificus other_names: - PPA03947 - GENEPREDICTION_SNAP300000060367 - UMM-S7-6.31 - PPA03947.1 - PP73670 - PPA03947 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00093501 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA37719 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00276088 label: PPA37719 other_names: - PPA37719 - PPA37719.1 - PP70849 - PPA37719 taxonomy: p_pacificus other_names: - PPA37719 - PPA37719.1 - PP70849 - PPA37719 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00276088 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans metl-18. label: SRAE_X000174600 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans metl-18. id: WBGene00267323 label: SRAE_X000174600 other_names: - SRAE_X000174600 - SRAE_X000174600.1 - SRP05216 - SRAE_X000174600 taxonomy: s_ratti other_names: - SRAE_X000174600 - SRAE_X000174600.1 - SRP05216 - SRAE_X000174600 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00267323 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: CBG20783 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00039705 label: CBG20783 other_names: - CBG20783 - CBG_20783 - CBG20783b.1 - CBG20783a.1 - CBG20783a - CBP19991 - CBG20783b - CBP43784 taxonomy: c_briggsae other_names: - CBG20783 - CBG_20783 - CBG20783b.1 - CBG20783a.1 - CBG20783a - CBP19991 - CBG20783b - CBP43784 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00039705 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans metl-18. label: Cbn-metl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans metl-18. id: WBGene00143084 label: Cbn-metl-18 other_names: - CBN04359 - CBN04359.1 - CBN04359 - CN03656 taxonomy: c_brenneri other_names: - CBN04359 - CBN04359.1 - CBN04359 - CN03656 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00143084 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: CBN03019 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00141744 label: CBN03019 other_names: - CBN03019 - CBN03019 - CBN03019.1 - CN06337 taxonomy: c_brenneri other_names: - CBN03019 - CBN03019 - CBN03019.1 - CN06337 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00141744 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: CBN06828 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00145553 label: CBN06828 other_names: - CBN06828 - CBN06828.1 - CBN06828 - CN06940 taxonomy: c_brenneri other_names: - CBN06828 - CBN06828.1 - CBN06828 - CN06940 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00145553 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: CBN20292 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00159017 label: CBN20292 other_names: - CBN20292 - CN23434 - CBN20292 - CBN20292.1 taxonomy: c_brenneri other_names: - CBN20292 - CN23434 - CBN20292 - CBN20292.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00159017 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans metl-18. label: Cre-metl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans metl-18. id: WBGene00054862 label: Cre-metl-18 other_names: - CRE25466 - cr01.sctg4.wum.217 - CRE25466 - CRE25466.1 - RP24717 taxonomy: c_remanei other_names: - CRE25466 - cr01.sctg4.wum.217 - CRE25466 - CRE25466.1 - RP24717 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00054862 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: CRE04025 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00057597 label: CRE04025 other_names: - CRE04025 - cr01.sctg9.wum.323 - RP29108 - CRE04025.1 - CRE04025 taxonomy: c_remanei other_names: - CRE04025 - cr01.sctg9.wum.323 - RP29108 - CRE04025.1 - CRE04025 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00057597 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA03950 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00093504 label: PPA03950 other_names: - PPA03950 - UMM-S7-6.34 - GENEPREDICTION_SNAP300000060370 - GENEPREDICTION_SNAP300000060371 - PPA03950.1 - PP60587 - PPA03950 taxonomy: p_pacificus other_names: - PPA03950 - UMM-S7-6.34 - GENEPREDICTION_SNAP300000060370 - GENEPREDICTION_SNAP300000060371 - PPA03950.1 - PP60587 - PPA03950 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00093504 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA19069 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00108623 label: PPA19069 other_names: - PPA19069 - UMM-S71-29.16 - GENEPREDICTION_SNAP300000075888 - PP63939 - PPA19069.1 - PPA19069 taxonomy: p_pacificus other_names: - PPA19069 - UMM-S71-29.16 - GENEPREDICTION_SNAP300000075888 - PP63939 - PPA19069.1 - PPA19069 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00108623 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA19073 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00108627 label: PPA19073 other_names: - PPA19073 - GENEPREDICTION_SNAP300000075892 - UMM-S71-29.18 - PPA19073 - PPA19073.1 - PP71445 taxonomy: p_pacificus other_names: - PPA19073 - GENEPREDICTION_SNAP300000075892 - UMM-S71-29.18 - PPA19073 - PPA19073.1 - PP71445 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00108627 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: PPA24415 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00113969 label: PPA24415 other_names: - PPA24415 - UMM-S13-81.33 - GENEPREDICTION_SNAP300000081299 - PPA24415.1 - PP69133 - PPA24415 taxonomy: p_pacificus other_names: - PPA24415 - UMM-S13-81.33 - GENEPREDICTION_SNAP300000081299 - PPA24415.1 - PP69133 - PPA24415 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00113969 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA37858 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00276227 label: PPA37858 other_names: - PPA37858 - PPA37858 - PPA37858.1 - PP58907 taxonomy: p_pacificus other_names: - PPA37858 - PPA37858 - PPA37858.1 - PP58907 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00276227 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: SRAE_1000031100 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00256905 label: SRAE_1000031100 other_names: - SRAE_1000031100 - SRP08193 - SRAE_1000031100 - SRAE_1000031100.1 taxonomy: s_ratti other_names: - SRAE_1000031100 - SRP08193 - SRAE_1000031100 - SRAE_1000031100.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00256905 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: TMUE_1000002881 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00287434 label: TMUE_1000002881 other_names: - TMUE_1000002881 - TMUE_s0017001000 - TMUE_1000002881 - TMP02329 - TMUE_1000002881.1 taxonomy: t_muris other_names: - TMUE_1000002881 - TMUE_s0017001000 - TMUE_1000002881 - TMP02329 - TMUE_1000002881.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00287434 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: TMUE_2000007318 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00288259 label: TMUE_2000007318 other_names: - TMUE_2000007318 - TMUE_s0025005800 - TMP06746 - TMUE_2000007318 - TMUE_2000007318.1 taxonomy: t_muris other_names: - TMUE_2000007318 - TMUE_s0025005800 - TMP06746 - TMUE_2000007318 - TMUE_2000007318.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00288259 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: Cbr-evl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00030843 label: Cbr-evl-18 other_names: - CBG09214 - CBG_09214 - CBG09214 - CBG09214.1 - CBP42372 taxonomy: c_briggsae other_names: - CBG09214 - CBG_09214 - CBG09214 - CBG09214.1 - CBP42372 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00030843 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: Cjp-evl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00119262 label: Cjp-evl-18 other_names: - CJA00058 - JA41055 - CJA00058 - CJA00058.1 taxonomy: c_japonica other_names: - CJA00058 - JA41055 - CJA00058 - CJA00058.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00119262 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: Cre-evl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00054808 label: Cre-evl-18 other_names: - CRE25146 - cr01.sctg4.wum.163 - RP47677 - CRE25146 - CRE25146.1 taxonomy: c_remanei other_names: - CRE25146 - cr01.sctg4.wum.163 - RP47677 - CRE25146 - CRE25146.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00054808 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: CRE28038 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00056450 label: CRE28038 other_names: - CRE28038 - cr01.sctg6.wum.521 - CRE28038 - CRE28038.1 - RP31147 taxonomy: c_remanei other_names: - CRE28038 - cr01.sctg6.wum.521 - CRE28038 - CRE28038.1 - RP31147 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00056450 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: OVOC10854 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00247663 label: OVOC10854 other_names: - OVOC10854 - OVOC10854.1 - OVOC10854 - OVP11157 taxonomy: o_volvulus other_names: - OVOC10854 - OVOC10854.1 - OVOC10854 - OVP11157 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00247663 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable double-stranded RNA binding activity. Is an ortholog of C. elegans Y48C3A.18. label: OVOC1560 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y48C3A.18. id: WBGene00238369 label: OVOC1560 other_names: - OVOC1560 - OVP00134 - OVOC1560 - OVOC1560.1 taxonomy: o_volvulus other_names: - OVOC1560 - OVP00134 - OVOC1560 - OVOC1560.1 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00238369 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Orthologous to human PRR18 (proline rich 18); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon. label: Prr18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Orthologous to human PRR18 (proline rich 18); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; Cuprizon id: RGD:1564079 label: Prr18 other_names: - ~ taxonomy: r_norvegicus other_names: - ~ page_type: gene species: key: r_norvegicus name: Rattus norvegicus taxonomy: genus: Rattus id: r_norvegicus species: norvegicus wbid: RGD:1564079 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: TMUE_0000000406 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00296346 label: TMUE_0000000406 other_names: - TMUE_0000000406 - TMP07838 - TMUE_0000000406.1 - TMUE_0000000406 taxonomy: t_muris other_names: - TMUE_0000000406 - TMP07838 - TMUE_0000000406.1 - TMUE_0000000406 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00296346 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: TMUE_2000008270 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00300196 label: TMUE_2000008270 other_names: - TMUE_2000008270 - TMUE_2000008270.1 - TMUE_2000008270 - TMP02291 taxonomy: t_muris other_names: - TMUE_2000008270 - TMUE_2000008270.1 - TMUE_2000008270 - TMP02291 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00300196 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: Cbn-lin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00142452 label: Cbn-lin-18 other_names: - CBN03727 - CBN03727 - CN25642 - CBN03727 - CBN03727.1 taxonomy: c_brenneri other_names: - CBN03727 - CBN03727 - CN25642 - CBN03727 - CBN03727.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00142452 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: CJA19549 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00175120 label: CJA19549 other_names: - CJA19549 - CJA19549a - CJA19549a.1 - CJA19549b - JA60527 - CJA19549b.1 - JA47316 taxonomy: c_japonica other_names: - CJA19549 - CJA19549a - CJA19549a.1 - CJA19549b - JA60527 - CJA19549b.1 - JA47316 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00175120 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: Cre-klp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00059346 label: Cre-klp-18 other_names: - CRE11026 - cr01.sctg14.wum.194 - CRE11026.1 - CRE11026 - RP31847 taxonomy: c_remanei other_names: - CRE11026 - cr01.sctg14.wum.194 - CRE11026.1 - CRE11026 - RP31847 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00059346 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: Cre-lin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00051903 label: Cre-lin-18 other_names: - CRE00854 - cr01.sctg0.wum.889 - CRE00854.1 - CRE00854 - RP45402 taxonomy: c_remanei other_names: - CRE00854 - cr01.sctg0.wum.889 - CRE00854.1 - CRE00854 - RP45402 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00051903 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: Cbn-klp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00155140 label: Cbn-klp-18 other_names: - CBN16415 - CBN16415 - CBN16415.1 - CN09031 taxonomy: c_brenneri other_names: - CBN16415 - CBN16415 - CBN16415.1 - CN09031 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00155140 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: OVOC2377 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00239186 label: OVOC2377 other_names: - OVOC2377 - OVOC2377 - OVP13417 - OVOC2377.1 taxonomy: o_volvulus other_names: - OVOC2377 - OVOC2377 - OVP13417 - OVOC2377.1 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00239186 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: TMUE_0000000202 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00287635 label: TMUE_0000000202 other_names: - TMUE_0000000202 - TMUE_s0018011400 - TMP03739 - TMUE_0000000202 - TMUE_0000000202.1 taxonomy: t_muris other_names: - TMUE_0000000202 - TMUE_s0018011400 - TMP03739 - TMUE_0000000202 - TMUE_0000000202.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00287635 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: TMUE_3000014898 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00302382 label: TMUE_3000014898 other_names: - TMUE_3000014898 - TMP04897 - TMUE_3000014898 - TMUE_3000014898.1 taxonomy: t_muris other_names: - TMUE_3000014898 - TMP04897 - TMUE_3000014898 - TMUE_3000014898.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00302382 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: Cbr-klp-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00037244 label: Cbr-klp-18 other_names: - CBG17679 - CBG_17679 - Cbr-klp-10 - CBG17679a.1 - CBG17679a - CBG17679b.1 - CBG17679c - CBG17679c.1 - CBG17679b - CBP46303 - CBP41481 - CBP38924 taxonomy: c_briggsae other_names: - CBG17679 - CBG_17679 - Cbr-klp-10 - CBG17679a.1 - CBG17679a - CBG17679b.1 - CBG17679c - CBG17679c.1 - CBG17679b - CBP46303 - CBP41481 - CBP38924 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00037244 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: Cjp-lin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00138082 label: Cjp-lin-18 other_names: - CJA18878 - CJA18878.1 - CJA18878 - JA17043 taxonomy: c_japonica other_names: - CJA18878 - CJA18878.1 - CJA18878 - JA17043 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00138082 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Zinc finger, RING-type. Is an ortholog of C. elegans vps-18. In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in apoptotic cell clearance." label: SRAE_2000313500 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans vps-18. - In C. elegans, vps-18 is involved in endosome organization and phagosome-lysosome fusion involved in id: WBGene00263355 label: SRAE_2000313500 other_names: - SRAE_2000313500 - SRP09673 - SRAE_2000313500 - SRAE_2000313500.1 taxonomy: s_ratti other_names: - SRAE_2000313500 - SRP09673 - SRAE_2000313500 - SRAE_2000313500.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00263355 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans lin-18. In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved in cell fate determination; axis specification; and positive regulation of axon guidance. label: Cbr-lin-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans lin-18. - In C. elegans, lin-18 is involved in several processes, including asymmetric protein localization involved id: WBGene00034859 label: Cbr-lin-18 other_names: - CBG14316 - CBG_14316 - CBP47154 - CBG14316.1 - CBG14316 taxonomy: c_briggsae other_names: - CBG14316 - CBG_14316 - CBP47154 - CBG14316.1 - CBG14316 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00034859 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: SRAE_2000296000 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00263179 label: SRAE_2000296000 other_names: - SRAE_2000296000 - SR01888 - SRP00654 - SRAE_2000296000.1 - SRAE_2000296000 taxonomy: s_ratti other_names: - SRAE_2000296000 - SR01888 - SRP00654 - SRAE_2000296000.1 - SRAE_2000296000 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00263179 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: Bma-evl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00224074 label: Bma-evl-18 other_names: - Bm3813 - Bm1_17910A - TAG3813 - Bm1_17910 - Bm3813 - Bm3813.1 - BM28765 taxonomy: b_malayi other_names: - Bm3813 - Bm1_17910A - TAG3813 - Bm1_17910 - Bm3813 - Bm3813.1 - BM28765 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00224074 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: CBG21009 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00039895 label: CBG21009 other_names: - CBG21009 - CBG_21009 - CBG21009a.1 - CBG21009b - CBG21009b.1 - CBP36631 - CBP04975 - CBG21009a taxonomy: c_briggsae other_names: - CBG21009 - CBG_21009 - CBG21009a.1 - CBG21009b - CBG21009b.1 - CBP36631 - CBP04975 - CBG21009a page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00039895 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: Cbn-evl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00144792 label: Cbn-evl-18 other_names: - CBN06067 - CBN06067 - CN00316 - CBN06067.1 taxonomy: c_brenneri other_names: - CBN06067 - CBN06067 - CN00316 - CBN06067.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00144792 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: CBN15404 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00154129 label: CBN15404 other_names: - CBN15404 - CBN15404.1 - CN27777 - CBN15404 taxonomy: c_brenneri other_names: - CBN15404 - CBN15404.1 - CN27777 - CBN15404 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00154129 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: CJA40439 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00216287 label: CJA40439 other_names: - CJA40439 - CJA40439 - CJA40439.1 - JA47907 taxonomy: c_japonica other_names: - CJA40439 - CJA40439 - CJA40439.1 - JA47907 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00216287 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans metl-18. label: Cjp-metl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans metl-18. id: WBGene00215463 label: Cjp-metl-18 other_names: - CJA39616 - JA06169 - CJA39616.1 - CJA39616 taxonomy: c_japonica other_names: - CJA39616 - JA06169 - CJA39616.1 - CJA39616 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00215463 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be involved in DNA replication initiation. Is an ortholog of C. elegans evl-18. label: Ovo-evl-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans evl-18. id: WBGene00245698 label: Ovo-evl-18 other_names: - OVOC8889 - OVOC8889.1 - OVOC8889 - OVP06702 taxonomy: o_volvulus other_names: - OVOC8889 - OVOC8889.1 - OVOC8889 - OVP06702 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00245698 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable phosphatidylinositol-4-phosphate binding activity. Is an ortholog of C. elegans Y47G6A.18. label: OVOC1420 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y47G6A.18. id: WBGene00238229 label: OVOC1420 other_names: - OVOC1420 - OVOC1420.1 - OVP09625 - OVOC1420 taxonomy: o_volvulus other_names: - OVOC1420 - OVOC1420.1 - OVP09625 - OVOC1420 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00238229 - allele: - class: variation id: WBVar00601256 label: tu92 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein kinase activity. Is an ortholog of C. elegans T19D2.2 and lin-18. label: PPA00022 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans T19D2.2 and lin-18. id: WBGene00089576 label: PPA00022 other_names: - PPA00022 - Ppa-prl-1 - GENEPREDICTION_SNAP300000057152 - GENEPREDICTION_SNAP300000083955 - UMM-S57-18.32 - PPA00022 - PPA00022.1 - PP51809 taxonomy: p_pacificus other_names: - PPA00022 - Ppa-prl-1 - GENEPREDICTION_SNAP300000057152 - GENEPREDICTION_SNAP300000083955 - UMM-S57-18.32 - PPA00022 - PPA00022.1 - PP51809 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00089576 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA03949 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00093503 label: PPA03949 other_names: - PPA03949 - UMM-S7-6.33 - GENEPREDICTION_SNAP300000060369 - PP58222 - PPA03949 - PPA03949.1 taxonomy: p_pacificus other_names: - PPA03949 - UMM-S7-6.33 - GENEPREDICTION_SNAP300000060369 - PP58222 - PPA03949 - PPA03949.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00093503 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." label: PPA06378 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domain: Abnormal cell migration protein 18-like." id: WBGene00095932 label: PPA06378 other_names: - PPA06378 - UMM-S2842-9.62 - GENEPREDICTION_SNAP300000062742 - GENEPREDICTION_SNAP300000062743 - PPA06378 - PP51067 - PPA06378.1 taxonomy: p_pacificus other_names: - PPA06378 - UMM-S2842-9.62 - GENEPREDICTION_SNAP300000062742 - GENEPREDICTION_SNAP300000062743 - PPA06378 - PP51067 - PPA06378.1 page_type: gene species: key: p_pacificus name: Pristionchus pacificus taxonomy: genus: Pristionchus id: p_pacificus species: pacificus wbid: WBGene00095932 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Is an ortholog of C. elegans Y17G7B.18. label: TMUE_3000014312 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans Y17G7B.18. id: WBGene00295112 label: TMUE_3000014312 other_names: - TMUE_3000014312 - TMUE_s0248001200 - TMUE_3000014312.1 - TMUE_3000014312 - TMP00221 taxonomy: t_muris other_names: - TMUE_3000014312 - TMUE_s0248001200 - TMUE_3000014312.1 - TMUE_3000014312 - TMP00221 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00295112 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: CJA17299 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00136503 label: CJA17299 other_names: - CJA17299 - JA08054 - CJA17299.1 - CJA17299 taxonomy: c_japonica other_names: - CJA17299 - JA08054 - CJA17299.1 - CJA17299 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00136503 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable ATP binding activity; microtubule binding activity; and microtubule motor activity. Predicted to be involved in microtubule-based movement. Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. label: CJA34153 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans klp-18. In C. elegans, klp-18 is involved in meiotic spindle assembly. id: WBGene00210000 label: CJA34153 other_names: - CJA34153 - CJA34153b - CJA34153a.1 - CJA34153a - CJA34153b.1 - JA51999 - JA62244 taxonomy: c_japonica other_names: - CJA34153 - CJA34153b - CJA34153a.1 - CJA34153a - CJA34153b.1 - JA51999 - JA62244 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00210000 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Is predicted to encode a protein with the following domains: Calycin and EGF-like domain. Is an ortholog of C. elegans ZC13.10 and mab-7." label: Ovo-mab-7 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ZC13.10 and mab-7. id: WBGene00242506 label: Ovo-mab-7 other_names: - OVOC5697 - OVP14345 - OVOC5697.1 - OVOC5697 taxonomy: o_volvulus other_names: - OVOC5697 - OVP14345 - OVOC5697.1 - OVOC5697 page_type: gene species: key: o_volvulus name: Onchocerca volvulus taxonomy: genus: Onchocerca id: o_volvulus species: volvulus wbid: WBGene00242506 - allele: - class: variation id: WBVar01145112 label: gk475882 - class: variation id: WBVar00502949 label: gk279706 - class: variation id: WBVar01145103 label: gk467968 - class: variation id: WBVar01145114 label: gk695038 - class: variation id: WBVar01145143 label: gk478699 - class: variation id: WBVar00502942 label: gk279699 - class: variation id: WBVar01145104 label: gk615196 - class: variation id: WBVar01145109 label: gk505695 - class: variation id: WBVar01145122 label: gk372599 - class: variation id: WBVar02148559 label: ac3 - class: variation id: WBVar01145127 label: gk802432 - class: variation id: WBVar00502954 label: gk279711 - class: variation id: WBVar01145141 label: gk608159 - class: variation id: WBVar01145142 label: gk900793 - class: variation id: WBVar01145131 label: gk779371 - class: variation id: WBVar00502951 label: gk279708 - class: variation id: WBVar00094278 label: ok3211 - class: variation id: WBVar01145137 label: gk328072 - class: variation id: WBVar01145102 label: gk899697 - class: variation id: WBVar00502946 label: gk279703 - class: variation id: WBVar00502941 label: gk279698 - class: variation id: WBVar01145113 label: gk357514 - class: variation id: WBVar00502944 label: gk279701 - class: variation id: WBVar01145110 label: gk344298 - class: variation id: WBVar01500067 label: gk964260 - class: variation id: WBVar01145108 label: gk316532 - class: variation id: WBVar01145130 label: gk788220 - class: variation id: WBVar01145120 label: gk905797 - class: variation id: WBVar01145125 label: gk801720 - class: variation id: WBVar01145119 label: gk344299 - class: variation id: WBVar01145121 label: gk937648 - class: variation id: WBVar01145115 label: gk640763 - class: variation id: WBVar00502947 label: gk279704 - class: variation id: WBVar00502957 label: gk279714 - class: variation id: WBVar01145138 label: gk612687 - class: variation id: WBVar00276043 label: ok5885 - class: variation id: WBVar01145116 label: gk709140 - class: variation id: WBVar00502945 label: gk279702 - class: variation id: WBVar00502959 label: gk279716 - class: variation id: WBVar00502961 label: gk279718 - class: variation id: WBVar00502952 label: gk279709 - class: variation id: WBVar01145106 label: gk535316 - class: variation id: WBVar01145139 label: gk867017 - class: variation id: WBVar01145100 label: gk328131 - class: variation id: WBVar01145126 label: gk578682 - class: variation id: WBVar01145133 label: gk325582 - class: variation id: WBVar00502953 label: gk279710 - class: variation id: WBVar01145105 label: gk363734 - class: variation id: WBVar01145144 label: gk670577 - class: variation id: WBVar02152636 label: tm12379 - class: variation id: WBVar00502943 label: gk279700 - class: variation id: WBVar01145101 label: gk346288 - class: variation id: WBVar01145140 label: gk618025 - class: variation id: WBVar00502955 label: gk279712 - class: variation id: WBVar01145111 label: gk900792 - class: variation id: WBVar01145129 label: gk725108 - class: variation id: WBVar00502950 label: gk279707 - class: variation id: WBVar00502956 label: gk279713 - class: variation id: WBVar02139258 label: h11582 - class: variation id: WBVar01145118 label: gk898116 - class: variation id: WBVar01145107 label: gk791083 - class: variation id: WBVar01145128 label: gk866337 - class: variation id: WBVar01145099 label: gk861847 - class: variation id: WBVar00502958 label: gk279715 - class: variation id: WBVar02139257 label: h12828 - class: variation id: WBVar01145134 label: gk384153 - class: variation id: WBVar02153565 label: crg9070 - class: variation id: WBVar01145132 label: gk644968 - class: variation id: WBVar01145124 label: gk811924 - class: variation id: WBVar01145135 label: gk520706 - class: variation id: WBVar00601209 label: gkDf37 - class: variation id: WBVar01145117 label: gk472887 - class: variation id: WBVar00502960 label: gk279717 - class: variation id: WBVar00502948 label: gk279705 - class: variation id: WBVar01145123 label: gk663664 - class: variation id: WBVar01145098 label: gk541990 - class: variation id: WBVar01145136 label: gk368626 dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable lipid transporter activity. Predicted to be involved in lipid transport. Located in cytoplasmic vesicle; vesicle lumen; and yolk granule. Expressed in embryonic cell; gonad; intestine; oocyte; and pseudocoelom. label: vit-2 legacy_description: vit-2 encodes the vitellogenin homolog YP170; vit-2 is expressed in the adult hermaphrodite intestine and VIT-2 is secreted into the pseudocoelomic space before being taken up by developing oocytes; vit-2 expression is regulated in a sex-, stage-, and tissue-specific manner by the ELT-2/GATA and MAB-3 transcription factors. merged_into: ~ name: class: gene highlight: description_all: - ; vit-2 expression is regulated in a sex-, stage-, and tissue-specific manner by the ELT-2/GATA and MAB id: WBGene00006926 label: vit-2 other_names: - C42D8.2 - CELE_C42D8.2 - C42D8.2 - CE06950 - C42D8.2.1 taxonomy: c_elegans other_names: - C42D8.2 - CELE_C42D8.2 - C42D8.2 - CE06950 - C42D8.2.1 page_type: gene species: key: c_elegans name: Caenorhabditis elegans taxonomy: genus: Caenorhabditis id: c_elegans species: elegans wbid: WBGene00006926 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable helicase activity. Is an ortholog of C. elegans ugt-16; ugt-18; and C44H9.4. label: CBG24231 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans ugt-16; ugt-18; and C44H9.4. id: WBGene00042393 label: CBG24231 other_names: - CBG24231 - CBG_24231 - CBG24231.1 - CBP40806 - CBG24231 taxonomy: c_briggsae other_names: - CBG24231 - CBG_24231 - CBG24231.1 - CBP40806 - CBG24231 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00042393 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to be located in membrane. Is an ortholog of C. elegans tsp-18 and tsp-7. label: TMUE_1000004656 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans tsp-18 and tsp-7. id: WBGene00295181 label: TMUE_1000004656 other_names: - TMUE_1000004656 - TMUE_s0257001000 - TMUE_1000004656 - TMP06854 - TMUE_1000004656.1 taxonomy: t_muris other_names: - TMUE_1000004656 - TMUE_s0257001000 - TMUE_1000004656 - TMP06854 - TMUE_1000004656.1 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00295181 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of C. elegans rab-18. label: Cbr-rab-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans rab-18. id: WBGene00035481 label: Cbr-rab-18 other_names: - CBG15153 - CBG_15153 - CBG15153 - CBP18335 - CBG15153.1 taxonomy: c_briggsae other_names: - CBG15153 - CBG_15153 - CBG15153 - CBP18335 - CBG15153.1 page_type: gene species: key: c_briggsae name: Caenorhabditis briggsae taxonomy: genus: Caenorhabditis id: c_briggsae species: briggsae wbid: WBGene00035481 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable structural molecule activity. Is an ortholog of C. elegans npp-18 and npp-20. label: TMUE_2000008467 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans npp-18 and npp-20. id: WBGene00285953 label: TMUE_2000008467 other_names: - TMUE_2000008467 - TMUE_s0006004100 - TMUE_2000008467.1 - TMP00628 - TMUE_2000008467 taxonomy: t_muris other_names: - TMUE_2000008467 - TMUE_s0006004100 - TMUE_2000008467.1 - TMP00628 - TMUE_2000008467 page_type: gene species: key: t_muris name: Trichuris muris taxonomy: genus: Trichuris id: t_muris species: muris wbid: WBGene00285953 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of C. elegans rab-18. label: Cbn-rab-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans rab-18. id: WBGene00142155 label: Cbn-rab-18 other_names: - CBN03430 - CN26537 - CBN03430.1 - CBN03430 taxonomy: c_brenneri other_names: - CBN03430 - CN26537 - CBN03430.1 - CBN03430 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00142155 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable GTP binding activity and GTPase activity. Is an ortholog of C. elegans rab-18. label: Cjp-rab-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans rab-18. id: WBGene00125135 label: Cjp-rab-18 other_names: - CJA05931 - CJA05931 - JA48586 - CJA05931.1 taxonomy: c_japonica other_names: - CJA05931 - CJA05931 - JA48586 - CJA05931.1 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00125135 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: "Enriched in digestive tract based on proteomic studies. Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. Is an ortholog of C. elegans C54G4.7." label: Bm2938 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - "Is predicted to encode a protein with the following domains: Alpha/beta hydrolase domain containing 18" - ; Alpha/beta hydrolase domain-containing protein 18; and Alpha/Beta hydrolase fold. id: WBGene00223199 label: Bm2938 other_names: - Bm2938 - Bm1_26805 - TAG11284 - TAG2938 - Bm1_26805A - Bm2938.1 - Bm2938 - BM43756 taxonomy: b_malayi other_names: - Bm2938 - Bm1_26805 - TAG11284 - TAG2938 - Bm1_26805A - Bm2938.1 - Bm2938 - BM43756 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00223199 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans daf-18. In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. label: Bma-daf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans daf-18. - In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive id: WBGene00225891 label: Bma-daf-18 other_names: - Bm5630 - TAG12547 - TAG5630 - Bm1_36650 - Bm5630b - BM23741 - Bm5630a - Bm5630b.1 - BM46314 - Bm5630a.1 taxonomy: b_malayi other_names: - Bm5630 - TAG12547 - TAG5630 - Bm1_36650 - Bm5630b - BM23741 - Bm5630a - Bm5630b.1 - BM46314 - Bm5630a.1 page_type: gene species: key: b_malayi name: Brugia malayi taxonomy: genus: Brugia id: b_malayi species: malayi wbid: WBGene00225891 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans daf-18. In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. label: Cjp-daf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans daf-18. - In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive id: WBGene00124009 label: Cjp-daf-18 other_names: - CJA04805 - CJA04805 - CJA04805.1 - JA48596 taxonomy: c_japonica other_names: - CJA04805 - CJA04805 - CJA04805.1 - JA48596 page_type: gene species: key: c_japonica name: Caenorhabditis japonica taxonomy: genus: Caenorhabditis id: c_japonica species: japonica wbid: WBGene00124009 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans daf-18. In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. label: Cre-daf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans daf-18. - In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive id: WBGene00071877 label: Cre-daf-18 other_names: - CRE22193 - cr01.sctg287.wum.2 - RP28668 - CRE22193 - CRE22193.1 taxonomy: c_remanei other_names: - CRE22193 - cr01.sctg287.wum.2 - RP28668 - CRE22193 - CRE22193.1 page_type: gene species: key: c_remanei name: Caenorhabditis remanei taxonomy: genus: Caenorhabditis id: c_remanei species: remanei wbid: WBGene00071877 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans daf-18. In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. label: SRAE_X000132800 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans daf-18. - In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive id: WBGene00266895 label: SRAE_X000132800 other_names: - SRAE_X000132800 - SR01742 - SRP04669 - SRAE_X000132800 - SRAE_X000132800.1 taxonomy: s_ratti other_names: - SRAE_X000132800 - SR01742 - SRP04669 - SRAE_X000132800 - SRAE_X000132800.1 page_type: gene species: key: s_ratti name: Strongyloides ratti taxonomy: genus: Strongyloides id: s_ratti species: ratti wbid: WBGene00266895 - allele: ~ dead: !!perl/scalar:JSON::PP::Boolean 0 description: Predicted to enable protein tyrosine phosphatase activity. Is an ortholog of C. elegans daf-18. In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive regulation of dauer larval development; and positive regulation of positive chemotaxis. label: Cbn-daf-18 legacy_description: ~ merged_into: ~ name: class: gene highlight: description_all: - Is an ortholog of C. elegans daf-18. - In C. elegans, daf-18 is involved in several processes, including determination of adult lifespan; positive id: WBGene00150057 label: Cbn-daf-18 other_names: - CBN11332 - CBN11332 - CN02190 - CBN11332 - CBN11332.1 taxonomy: c_brenneri other_names: - CBN11332 - CBN11332 - CN02190 - CBN11332 - CBN11332.1 page_type: gene species: key: c_brenneri name: Caenorhabditis brenneri taxonomy: genus: Caenorhabditis id: c_brenneri species: brenneri wbid: WBGene00150057 species: ~ type: gene uri: search/gene/mab-18/all