- hmit-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol transport and transmembrane transport. Located in apical plasma membrane. Expressed in intestinal cell. Is an ortholog of human SLC2A13 (solute carrier family 2 member 13).
- hmit-1.3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol transport and transmembrane transport. Located in apical plasma membrane. Expressed in amphid sheath cell; head; and phasmid sheath cell. Is an ortholog of human SLC2A13 (solute carrier family 2 member 13).
- hmit-1.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable myo-inositol:proton symporter activity. Predicted to be involved in myo-inositol transport and transmembrane transport. Located in apical plasma membrane and basal plasma membrane. Expressed in amphid sheath cell; excretory canal; and phasmid sheath cell. Is an ortholog of human SLC2A13 (solute carrier family 2 member 13).
- myo-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction and sarcomere organization. Predicted to be located in cytoplasm and myosin filament. Predicted to be part of muscle myosin complex. Expressed in neurons and pharynx. Human ortholog(s) of this gene implicated in several diseases, including congenital heart disease (multiple); distal myopathy 1; and intrinsic cardiomyopathy (multiple). Is an ortholog of several human genes including MYH1 (myosin heavy chain 1); MYH2 (myosin heavy chain 2); and MYH3 (myosin heavy chain 3).
- arf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable GTP binding activity and GTPase activity. Involved in negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; and positive regulation of endosome to plasma membrane protein transport. Located in basolateral plasma membrane; cytoplasmic side of apical plasma membrane; and recycling endosome membrane. Expressed in several structures, including excretory cell; intestine; pharyngeal muscle cell; ventral nerve cord; and vulva. Is an ortholog of human ARF6 (ADP ribosylation factor 6).
- unc-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables SH3 domain binding activity; cytoskeletal protein binding activity; and protein kinase binding activity. Involved in several processes, including positive regulation of ovulation; positive regulation of sarcomere organization; and skeletal muscle myosin thick filament assembly. Located in A band and myosin filament. Expressed in alimentary muscle; body wall musculature; gonad; vulval muscle; and in male. Is an ortholog of human MYH16 (myosin heavy chain 16 (pseudogene)).
- plc-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables GTPase inhibitor activity; phosphatidylinositol phospholipase C activity; and small GTPase binding activity. Involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process; defense response to Gram-positive bacterium; and positive regulation of protein import into nucleus. Expressed in excretory system; intestine; neurons; spermatheca; and vulva. Human ortholog(s) of this gene implicated in gastric adenocarcinoma; nephrotic syndrome type 2; and nephrotic syndrome type 3. Is an ortholog of human PLCE1 (phospholipase C epsilon 1).