orai-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables store-operated calcium channel activity. Involved in ovulation and store-operated calcium entry. Located in apical plasma membrane and basolateral plasma membrane. Part of voltage-gated calcium channel complex. Expressed in gonadal sheath cell; head; and tail. Human ortholog(s) of this gene implicated in immunodeficiency 9 and tubular aggregate myopathy 2. Is an ortholog of human ORAI2 (ORAI calcium release-activated calcium modulator 2) and ORAI3 (ORAI calcium release-activated calcium modulator 3).