- Gr39a [Search on AGR]
Drosophila melanogaster Gustatory receptor 39a (Gr39a) encodes a member of the gustatory receptors and is expressed in gustatory sensilla receptor neurons. They detect tastants (non-volatile compounds) via contact chemosensation.
- Gr68a [Search on AGR]
Drosophila melanogaster Gustatory receptor 68a (Gr68a) encodes a member of the seven-transmembrane chemoreceptor family expressed in gustatory sensilla receptor neurons. It mediates courtship behavior and functions as a sensor for sex pheromones and mechanosensory stimuli.
- tyra-3 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable G protein-coupled serotonin receptor activity; neurotransmitter receptor activity; and octopamine receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to be located in dendrite. Expressed in SDQ; gonad; head neurons; and vulva. Used to study Parkinson's disease.
- tkr-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable tachykinin receptor activity. Predicted to be involved in tachykinin receptor signaling pathway. Predicted to be located in plasma membrane. Expressed in ADEsoL; ADEsoR; PDEsoL; and PDEsoR. Human ortholog(s) of this gene implicated in exercise-induced bronchoconstriction and hypogonadotropic hypogonadism 11 with or without anosmia. Is an ortholog of human TACR1 (tachykinin receptor 1) and TACR3 (tachykinin receptor 3).
- nompA [Search on AGR]
Drosophila melanogaster no mechanoreceptor potential A (nompA) encodes an apical extracellular matrix protein involved in mechanotransduction. In mechanosensory sensilla, the product of nompAis transported to and incorporated into an apical extracellular cap, which encloses the tips of sensory cilia and connects them to force-transmitting structures. nompA loss causes sensory defects including deafness, touch-insensitivity, and lack of coordination due to loss of proprioception.
- daf-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in several processes, including negative regulation of transcription by RNA polymerase II; positive regulation of dauer larval development; and regulation of insulin receptor signaling pathway. Located in cytoplasmic vesicle and plasma membrane. Expressed in several structures, including cuticle; excretory system; interfacial epithelial cell; neurons; and vulval cell. Is an ortholog of human PTCHD3 (patched domain containing 3 (gene/pseudogene)).
- lit-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables beta-catenin binding activity and protein serine/threonine kinase activity. Involved in several processes, including cell fate commitment; polarity specification of proximal/distal axis; and positive regulation of nematode male tail tip morphogenesis. Located in cell cortex and nucleus. Part of serine/threonine protein kinase complex. Expressed in several structures, including hermaphrodite gonad; pharynx; tail hypodermis; and vulva. Is an ortholog of human NLK (nemo like kinase).
- wrt-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable peptidase activity. Predicted to be involved in cell-cell signaling; protein autoprocessing; and system development. Predicted to be located in cell surface; extracellular region; and plasma membrane. Expressed in anterior ganglion (ant); hypodermis; and neuronal sheath cell. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; gastrointestinal system cancer (multiple); and glomerulonephritis (multiple). Is an ortholog of human SHH (sonic hedgehog signaling molecule).