ceh-33 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Expressed in head and head muscle. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant nonsyndromic deafness 23; carcinoma (multiple); and optic disc anomalies with retinal and/or macular dystrophy. Is an ortholog of human SIX1 (SIX homeobox 1); SIX2 (SIX homeobox 2); and SIX6 (SIX homeobox 6).
ceh-32 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in post-embryonic animal morphogenesis. Located in nucleus. Expressed in several structures, including anterior hypodermis; gonadal sheath cell; head ganglion; pharyngeal neurons; and somatic nervous system. Human ortholog(s) of this gene implicated in several diseases, including holoprosencephaly 2; optic disc anomalies with retinal and/or macular dystrophy; and renal Wilms' tumor. Is an ortholog of human SIX3 (SIX homeobox 3) and SIX6 (SIX homeobox 6).