sqv-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables glucuronosyltransferase activity. Involved in several processes, including chondroitin sulfate biosynthetic process; multicellular organism reproduction; and pharynx development. Located in membrane. Human ortholog(s) of this gene implicated in Barrett's esophagus; Larsen-like syndrome B3GAT3 type; and schizophrenia. Is an ortholog of human B3GAT3 (
beta-1,3-glucuronyltransferase 3).
spe-8 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Involved in spermatid development. Located in plasma membrane. Expressed in sperm and spermatocyte.
spe-44 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in positive regulation of transcription by RNA polymerase II and spermatogenesis. Located in autosome. Expressed in germ line; sperm; and in male. Is an ortholog of human GMEB1 (glucocorticoid modulatory element binding protein 1) and GMEB2 (glucocorticoid modulatory element binding protein 2).
spe-39 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in germ cell development; vacuolar protein processing; and vacuolar transport. Located in cytoplasm. Expressed in male-specific anatomical entity and in male. Human ortholog(s) of this gene implicated in arthrogryposis, renal dysfunction, and cholestasis 2. Is an ortholog of human VIPAS39 (VPS33B interacting protein, apical-basolateral polarity regulator,
spe-39 homolog).
spe-6 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein serine/threonine kinase activity. Involved in male meiosis chromosome separation; regulation of protein localization; and spermatid differentiation. Predicted to be located in nucleus. Expressed in sperm.
spe-10 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including amoeboid sperm motility; cellular component organization; and spermatid development. Located in membrane-bounded organelle. Expressed in spermatid.
spe-9 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable signaling receptor binding activity. Involved in single fertilization. Located in several cellular components, including cell surface; cytoplasm; and pseudopodium. Expressed in sperm and spermatid. Human ortholog(s) of this gene implicated in several diseases, including Adams-Oliver syndrome; limb ischemia; and temporal arteritis. Is an ortholog of human DLL1 (delta like canonical Notch ligand 1) and DLL4 (delta like canonical Notch ligand 4).
spe-4 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable endopeptidase activity. Involved in cellular component organization; protein localization; and spermatid development. Located in intracellular membrane-bounded organelle. Expressed in male.
spe-41 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Enables store-operated calcium channel activity. Involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization. Located in cytoplasmic vesicle and pseudopodium membrane. Expressed in sperm and spermatid.
spe-26 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin binding activity. Predicted to be located in cytoplasm and cytoskeleton. Expressed in spermatocyte and in male. Human ortholog(s) of this gene implicated in spermatogenic failure 11. Is an ortholog of human KLHL10 (kelch like family member 10).
spe-5 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable proton-transporting ATPase activity, rotational mechanism. Involved in intracellular pH reduction; positive regulation of programmed cell death; and spermatocyte division. Located in cytoplasm. Expressed in sperm and spermatocyte. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy and renal tubular acidosis. Is an ortholog of human ATP6V1B1 (ATPase H+ transporting V1 subunit B1) and ATP6V1B2 (ATPase H+ transporting V1 subunit B2).
spe-15 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable actin filament binding activity and microfilament motor activity. Involved in organelle localization and spermatid development. Predicted to be located in actin cytoskeleton and endocytic vesicle. Predicted to be part of myosin complex. Expressed in primary spermatocyte. Human ortholog(s) of this gene implicated in auditory system disease (multiple) and reproductive organ cancer (multiple). Is an ortholog of human MYO6 (myosin VI).
swm-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable serine-type endopeptidase inhibitor activity. Involved in spermatid development. Located in extracellular space and secretory vesicle. Expressed in body wall musculature; coelomocyte; reproductive tract; and in male.
OVOC787 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable ATP binding activity; actin filament binding activity; and cytoskeletal motor activity. Predicted to be part of myosin complex. Is an ortholog of C. elegans
spe-15. In C. elegans,
spe-15 is involved in organelle localization and spermatid development.
OVOC10351 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable ATP binding activity; actin filament binding activity; and cytoskeletal motor activity. Predicted to be part of myosin complex. Is an ortholog of C. elegans
spe-15. In C. elegans,
spe-15 is involved in organelle localization and spermatid development.
Cbn-spe-4.1 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Cbr-spe-39 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Is predicted to encode a protein with the following domains: Spermatogenesis-defective protein 39 and Vps16, C-terminal domain superfamily. Is an ortholog of C. elegans
spe-39. In C. elegans,
spe-39 is involved in germ cell development; vacuolar protein processing; and vacuolar transport.
Cjp-spe-39 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Is predicted to encode a protein with the following domains: Spermatogenesis-defective protein 39 and Vps16, C-terminal domain superfamily. Is an ortholog of C. elegans
spe-39. In C. elegans,
spe-39 is involved in germ cell development; vacuolar protein processing; and vacuolar transport.
Bma-spe-4.1 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
SRAE_1000350200 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
CBG11946 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Cbn-spe-4.2 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Cbr-spe-4 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Cre-spe-4 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Ppa-spe-39 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Is predicted to encode a protein with the following domains: Spermatogenesis-defective protein 39 and Vps16, C-terminal domain superfamily. Is an ortholog of C. elegans
spe-39. In C. elegans,
spe-39 is involved in germ cell development; vacuolar protein processing; and vacuolar transport.
PPA33196 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable ATP binding activity; actin filament binding activity; and cytoskeletal motor activity. Predicted to be part of myosin complex. Is an ortholog of C. elegans
spe-15. In C. elegans,
spe-15 is involved in organelle localization and spermatid development.
trp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport and regulation of cytosolic calcium ion concentration. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Expressed in ASER; SMDDL; SMDDR; SMDVL; and SMDVR. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1H; lung cancer; and stomach cancer. Is an ortholog of human TRPC4 (transient receptor potential cation channel subfamily C member 4) and TRPC5 (transient receptor potential cation channel subfamily C member 5).
Cjp-spe-4 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Cre-spe-39 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Is predicted to encode a protein with the following domains: Spermatogenesis-defective protein 39 and Vps16, C-terminal domain superfamily. Is an ortholog of C. elegans
spe-39. In C. elegans,
spe-39 is involved in germ cell development; vacuolar protein processing; and vacuolar transport.
Ovo-spe-4 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Bma-spe-41 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
Cre-spe-41 [Browse genome (BioProject PRJNA577507)] [Search on AGR]
Caenorhabditis remanei Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
TMUE_1000002600 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
TMUE_1000005030 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
TMUE_2000009879 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
Cbn-spe-41 [Browse genome (BioProject PRJNA20035)] [Search on AGR]
Caenorhabditis brenneri Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
Cjp-spe-41 [Browse genome (BioProject PRJNA12591)] [Search on AGR]
Caenorhabditis japonica Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
TMUE_1000002933 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
Bma-spe-4.2 [Browse genome (BioProject PRJNA10729)] [Search on AGR]
Brugia malayi Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
Ppa-spe-4 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable aspartic endopeptidase activity, intramembrane cleaving. Predicted to be involved in protein processing. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-4. In C. elegans,
spe-4 is involved in cellular component organization; protein localization; and spermatid development.
SRAE_1000251100 [Browse genome (BioProject PRJEB125)] [Search on AGR]
Strongyloides ratti Is predicted to encode a protein with the following domains: Spermatogenesis-defective protein 39 and Vps16, C-terminal domain superfamily. Is an ortholog of C. elegans
spe-39. In C. elegans,
spe-39 is involved in germ cell development; vacuolar protein processing; and vacuolar transport.
trp-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in calcium ion transmembrane transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to be located in plasma membrane. Predicted to be part of cation channel complex. Expressed in neurons and non-striated muscle. Used to study nicotine dependence. Human ortholog(s) of this gene implicated in several diseases, including cerebellar ataxia type 41; chronic fatigue syndrome; and focal segmental glomerulosclerosis 2. Is an ortholog of human TRPC3 (transient receptor potential cation channel subfamily C member 3); TRPC6 (transient receptor potential cation channel subfamily C member 6); and TRPC7 (transient receptor potential cation channel subfamily C member 7).
nphp-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Involved in protein localization to ciliary inversin compartment. Located in ciliary inversin compartment. Expressed in neurons. Human ortholog(s) of this gene implicated in hypertension and nephronophthisis 2. Is an ortholog of human INVS (inversin).
Cbr-spe-41 [Browse genome (BioProject PRJNA10731)] [Search on AGR]
Caenorhabditis briggsae Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
Ppa-spe-41 [Browse genome (BioProject PRJNA12644)] [Search on AGR]
Pristionchus pacificus Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
Ovo-spe-41 [Browse genome (BioProject PRJEB513)] [Search on AGR]
Onchocerca volvulus Predicted to enable calcium channel activity. Predicted to be involved in calcium ion transmembrane transport. Predicted to be located in membrane. Is an ortholog of C. elegans
spe-41. In C. elegans,
spe-41 is involved in calcium ion transport; intracellular calcium ion homeostasis; and single fertilization.
TMUE_2000009032 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
spe-6 and
prde-1 and members of the C. elegans ttbk gene class including C39H7.1. In C. elegans,
spe-6 is involved in male meiosis chromosome separation; regulation of protein localization; and spermatid differentiation.
TMUE_1000005661 [Browse genome (BioProject PRJEB126)] [Search on AGR]
Trichuris muris Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans
spe-6 and
prde-1 and members of the C. elegans ttbk gene class including C39H7.1. In C. elegans,
spe-6 is involved in male meiosis chromosome separation; regulation of protein localization; and spermatid differentiation.
nonu-1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable endonuclease activity. Human ortholog(s) of this gene implicated in several diseases, including alcoholic liver cirrhosis; hypomyelinating leukodystrophy 20; and restless legs syndrome. Is an ortholog of several human genes including CNP (2',3'-cyclic nucleotide 3' phosphodiesterase); N4BP2 (NEDD4 binding protein 2); and N4BP2L2 (NEDD4 binding protein 2 like 2).
pfd-2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable protein folding chaperone. Predicted to be involved in protein folding. Located in endoplasmic reticulum; sarcomere; and striated muscle dense body. Is an ortholog of human PFDN2 (prefoldin subunit 2).
pfkb-1.1 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).
pfkb-1.2 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable 6-phosphofructo-2-kinase activity and fructose-2,6-bisphosphate 2-phosphatase activity. Predicted to be involved in fructose 2,6-bisphosphate metabolic process. Predicted to be located in cytosol. Is an ortholog of several human genes including PFKFB1 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1); PFKFB2 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2); and PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3).
C03A7.13 [Browse genome (BioProject PRJNA13758)] [Search on AGR]
Caenorhabditis elegans Predicted to enable UDP-glycosyltransferase activity. Predicted to be located in membrane. Is an ortholog of several human genes including UGT2B10 (UDP glucuronosyltransferase family 2 member B10); UGT2B4 (UDP glucuronosyltransferase family 2 member B4); and UGT2B7 (UDP glucuronosyltransferase family 2 member B7).