Predicted to enable protein prenyltransferase activity and zinc ion binding activity. Predicted to contribute to protein farnesyltransferase activity. Predicted to be part of protein farnesyltransferase complex. Expressed in body wall musculature; neurons; pharyngeal muscle cell; rectal epithelial cell; and vulval cell. Is an ortholog of human CHURC1-FNTB (CHURC1-FNTB readthrough) and FNTB (farnesyltransferase, CAAX box, beta).
Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).
Enriched in male based on RNA-seq studies. Is affected by several genes including daf-2; csr-1; and nhr-114 based on microarray; tiling array; and RNA-seq studies.
Enriched in coelomocyte based on tiling array studies. Is affected by several genes including cyc-1; mrps-5; and nhr-114 based on microarray; tiling array; and RNA-seq studies.
Predicted to enable RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and nuclear receptor activity. Involved in regulation of gene expression. Acts upstream of with a positive effect on S-adenosylmethionine cycle. Located in nucleus. Expressed in germ line; hypodermis; and intestine. Human ortholog(s) of this gene implicated in obesity. Is an ortholog of human NR1H3 (nuclear receptor subfamily 1 group H member 3).
Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).