Enables zinc ion transmembrane transporter activity. Involved in intracellular zinc ion homeostasis; multicellular organismal reproductive process; and regulation of reproductive process. Located in membrane. Expressed in hypodermis; neurons; spermatocyte; ventral nerve cord; and vulva.
Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).
Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).
Is affected by several genes including daf-12; eat-2; and prg-1 based on tiling array and RNA-seq studies. Is affected by nicotine and sanguinarine based on quantitative PCR and RNA-seq studies. Used to study Parkinson's disease.
Is predicted to encode a protein with the following domains: Transmembrane protein 230/134; Transmembrane proteins 230/134; and Transmembrane protein 134.
Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination.