Predicted to enable AP-2 adaptor complex binding activity and protein serine/threonine kinase activity. Predicted to be involved in positive regulation of Notch signaling pathway and regulation of clathrin-dependent endocytosis. Predicted to be located in cytoplasm. Expressed in intestine; neurons; and pharynx. Is an ortholog of human GAK (cyclin G associated kinase).
Predicted to enable ATP binding activity and protein kinase activity. Is an ortholog of C. elegans dnj-25. In C. elegans, dnj-25 is involved in receptor-mediated endocytosis.
Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).
Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).