Enables ubiquitin-protein transferase activity. Involved in protein ubiquitination. Located in nucleus. Expressed in head neurons; tail neurons; and ventral nerve cord. Human ortholog(s) of this gene implicated in nonphotosensitive trichothiodystrophy 5. Is an ortholog of human RNF113A (ring finger protein 113A).
Predicted to be located in endoplasmic reticulum membrane. Expressed in head; neurons; spermatheca; and vulva. Is an ortholog of human TMEM41B (transmembrane protein 41B).
Predicted to be involved in negative regulation of apoptotic signaling pathway. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Expressed in excretory system; neurons; and pharyngeal muscle cell. Is an ortholog of human GRINA (glutamate ionotropic receptor NMDA type subunit associated protein 1).
Predicted to enable protein tag activity and ubiquitin protein ligase binding activity. Predicted to be involved in modification-dependent protein catabolic process and protein ubiquitination.