- Brugia_malayi_secretome_MFES
Secretome proteins of microfilariae of Brugia malayi. This is a large-scale proteomic analysis using mass spectrometry to identify the excretory-secretory (ES) products of the L3, L3 to L4 molting ES, adult male, adult female, and microfilarial stages of the filarial parasite Brugia malayi.
- Brugia_malayi_secretome_L3_ES
Secretome proteins of Brugia malayi L3 larvae. This is a large-scale proteomic analysis using mass spectrometry to identify the excretory-secretory (ES) products of the L3, L3 to L4 molting ES, adult male, adult female, and microfilarial stages of the filarial parasite Brugia malayi.
- Brugia_malayi_secretome_AFES
Secretome proteins of adult female Brugia malayi. This is a large-scale proteomic analysis using mass spectrometry to identify the excretory-secretory (ES) products of the L3, L3 to L4 molting ES, adult male, adult female, and microfilarial stages of the filarial parasite Brugia malayi.
- Brugia_malayi_secretome_AMES
Secretome proteins of adult male Brugia malayi. This is a large-scale proteomic analysis using mass spectrometry to identify the excretory-secretory (ES) products of the L3, L3 to L4 molting ES, adult male, adult female, and microfilarial stages of the filarial parasite Brugia malayi.
- Brugia_malayi_secretome_L3_MES
Secretome proteins of Brugia malayi L3 larvae molting into L4 stage. This is a large-scale proteomic analysis using mass spectrometry to identify the excretory-secretory (ES) products of the L3, L3 to L4 molting ES, adult male, adult female, and microfilarial stages of the filarial parasite Brugia malayi.
- conserved_RDE-1_cluster
C. elegans genes showing correlated conservation patterns with RDE-1 are predicted to function in small RNA pathways such as miRNA and siRNA-based gene silencing. The signature phylogenetic profile of the Argonaute proteins is that they are absent in 9 out of 31 Ascomycota species, 1 out of 3 Basidiomycota species, and 6 out of 14 protist species, but have not been lost in any of the 33 animal or 6 land plant species compared. High-confidence candidates from this analysis were tested for defects in RNAi silencing. RDE-1 was used to generate a rank-order list of proteins with the similar phylogenetic profiles.