- preQ1 synthase activity
Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP+ = 7-cyano-7-deazaguanine + 3 H+ + 2 NADPH.
- regulation of exit from mitosis
Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
- G2/M transition of mitotic cell cycle
The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.