In a wild-type animal at the Pn.pxx stage,
lin-11::gfp expression is typically detected in P5.ppx and P7.pax cells. However, in
lin-17(
n671) animals, the pattern of expression is defective in P7.p but not in P5.p progeny. The most frequent defect is a mirror image of the wild-type pattern in P7.p progeny. The other defect is either a graded or uniform distribution of GFP in all P7.p progeny. In VPC greatgranddaughter (Pn.pxxx stage), the overall level of
lin-11::GFP fluorescence in
lin-17(
n671) was considerably reduced in both the P5.p and P7.p lineage cells.