Although oga-1 mutants are not sensitive to 250 mm glucose stress in a wild-type background, in the daf-2 background, oga-1 mutants had reduced fertility at both the semipermissive (40% reduction in brood size) and restrictive(70% reduction) temperatures.
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oga-1 expression was upregulated, in the heat-shocked hsp::hbl-1 animals relative to the heat-shocked hsp::DsRed2 control animals, exceeding a two-fold difference at p < 0.05.