"A similar loss in UPR-ER activation was evident upon examination of transcript levels (Figure 1C). Levels of total
xbp-1 transcript increased 2-fold following tunicamycin treatment at day 1 of adulthood but were virtually unchanged upon tunicamycin treatment at day 5. Levels of spliced
xbp-1 transcript were increased around 20-fold by tunicamycin treatment at day 1, but very little increase in spliced transcript was observed by day 5."