"KIN-29 phosphorylates the HDA-4 class II histone deacetylase (HDAC) and inhibits the gene repression functions of HDA-4 and anMEF-2 MADS domain transcription factor."
"In addition we determined the gene expression of individual 31A genes by RT-PCR (Fig. 4). As indicated by the gene filter results these P450 forms are inducible by another class of substances. In accordance with the gene filters atrazine and phenobarbital induced 31A1 and 31A3. Pyrazol produced an induction of 31A3 and a more slight induction of 31A1. Furthermore, 31A3 was found to be inducible by toluene, lansoprasol, and primaquine, too."
"In addition we determined the gene expression of individual 31A genes by RT-PCR (Fig. 4). As indicated by the gene filter results these P450 forms are inducible by another class of substances. In accordance with the gene filters atrazine and phenobarbital induced 31A1 and 31A3. Pyrazol produced an induction of 31A3 and a more slight induction of 31A1. Furthermore, 31A3 was found to be inducible by toluene, lansoprasol, and primaquine, too."