mec-12 mutations enhanced
mec-15 synaptic and cell-body defects. One copy of
mec-12 significantly enhanced the Sam phenotype of
mec-15.
mec-15;
mec-12 double mutants had a Sam phenotype similar to that of
mec-12 mutants with enhanced penetrance of cell body phenotype. Finally, double heterozygotes (
mec-15/+;
mec-12/+) enhanced the Sam phenotypecompared to
mec-15/+ and
mec-12/+ animals.