FIGL-1-AAA forms homohexamer in solution and this interaction can be largely attributed to charge interactions mediated by two acidic residues in helix alpha-9a.
Y48A6B.8 expression was downregulated, in the heat-shocked hsp::hbl-1 animals relative to the heat-shocked hsp::DsRed2 control animals, exceeding a two-fold difference at p < 0.05.
"we examined the expression pattern of glutamate receptor subunits in an unc-42 mutant background. We confirmed that unc-42 is required for GLR-1 expression in AVA, AVD, AVE, and RMD neurons (Fig. 9A)."