"While interaction of RIC-3 with DEG-3 does not require assembly of DEG-3 with DES-2, it is enhanced by the presence of DES-2, suggesting that RIC-3 prefers DEG-3/DES-2 heteromers to DEG-3 monomers or homomers."
FEM-3 is absent from the distal wild-type adult gremlin detected by anti- FEM-3 antibodies. In nos-3(0), FEM-3 accumulates throughout the distal germline, supporting a role for NOS-3-mediated repression of fem-3 translation in this region.