RNAi targeting the transcription factor mep-1, which strongly regulates fos-1a expression, reduced GFP::HLH-2 fluorescence to a similar degree as fos-1 RNAi , suggesting that MEP-1 regulates GFP::HLH-2 indirectly through fos-1a.
fos-1 RNAi treatment of unc-40 mutants resulted in an increased block in AC invasion. Authors state this indicates that FOS-1A has functions in AC invasion that are independent of the UNC-6 pathway.