gem-4(
dx77) is capable of suppressing a reduction of
gon-2 activity mediated by RNAi. However,
gon-2(RNAi) did not completely eliminate
gon-2 activity. To reduce
gon-2 activity to a negligible level, authors performed
gon-2(RNAi) in a
gon-2(
q388) background. In these animals, no suppression by
gem-4(
dx77) was observed. Therefore, suppression by
gem-4(
dx77) requires that the level of
gon-2(+) activity be above a certain threshold.