Worms co-expressing BAX inhibitotor (BI) showed healthy dopamine neurons with normal neuron morphology and continuity, similar to that of GFP control animals.
Worms co-expressing PrP and BAX in dopamine only neurons showed healthy dopamine neurons with normal neuron morphology and continuity, similar to that of GFP control animals.
The expression of cyp-35a3, cyp-35a5 and cyp-35c1 was greatly increased by up to 100-fold after 1.5 hr TBZ exposure in gfp controls compared to those exposed to DMSO.
The expression of cyp-35a3, cyp-35a5 and cyp-35c1 was greatly increased by up to 100-fold after 1.5 hr TBZ exposure in gfp controls compared to those exposed to DMSO.
The expression of cyp-35a3, cyp-35a5 and cyp-35c1 was greatly increased by up to 100-fold after 1.5 hr TBZ exposure in gfp controls compared to those exposed to DMSO.
TDP-1::GFP was highly induced in the daf-2(e1370);TDP-1::GFP strain compared to TDP-1::GFP controls and was further elevated in daf-2(e1370) mutants exposed to stress.
when nhr-176 was targeted by RNAi the expression of cyp-35d1 was knocked down to approximately 37 8 % after DMSO exposure and to approximately 17 % 3 % after TBZ exposure compared to the gfp control. In other words the induction of cyp-35d1 is ablated in an nhr-176 (RNAi) background.