"When we analyzed the activation of UPRmt and ROS defense at day 3 of adulthood, we not only observed a continued activation of UPRmt, but now, unlike the situation at day 1, also a strong activation of the
sod-3 promoter in worms treated with AZD2281, NR (Figure 4C), or
pme-1 RNAi (Figure S4B)."