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[
Rivista Di Biologia Biology Forum,
1992]
Certain mutants of the nematode Caenorhabditis elegans exhibit an abnormal reiteration of specific cell divisions...
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[
Curr Biol,
1994]
Two genes that control dauer formation in the soil nematode Caenorhabditis elegans have direct effects on senescence.
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Research Resources Reporter (DHHS),
1986]
A comprehensive collection of the nematode Caenorhabditis elegans, including strains useful in research and in teaching genetics, is maintained at the Caenorhabditis Genetics Center at the University of Missouri in Columbia, Missouri.
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Sci Robot,
2021]
Analysis of <i>Caenorhabditis elegans</i> natural movement and optogenetic control of its muscle cells enable controlled locomotion.
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Methods Mol Biol,
2006]
The genome of the nematode Caenorhabditis elegans was the first animal genome sequenced. Subsequent sequencing of the Caenorhabditis briggsae genome enabled a comparison of the genomes of two nematode species. In this chapter, we describe the methods that we used to compare the C. elegans genome to that of C. briggsae. We discuss how these methods could be developed to compare the C. elegans and C. briggsae genomes to those of Caenorhabditis remanei, C. n. sp. represented by strains PB2801 and CB5161, among others (1), and Caenorhabditis japonica, which are currently being sequenced.
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Genome Biol,
2003]
The publication of the draft genome sequence of Caenorhabditis briggsae improves the annotation of the genome of its close relative Caenorhabditis elegans and will facilitate comparative genomics and the study of the evolutionary changes during development.
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[
Trends in Genetics,
1985]
Sexual phenotype in Caenorhabditis elegans is determined by a small number of control genes which are organized in a cascade of regulatory interactions.
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Expert Rev Anti Infect Ther,
2003]
The nematode worm, Caenorhabditis elegans, has been used to develop a facile model system of host-pathogen interactions to identify basic evolutionarily conserved pathways associated with microbial pathogenesis. The model involves the killing of Caenorhabditis elegans by a variety of human pathogens. Several virulence-related genes in a variety of pathogens previously shown to be involved in mammalian infection have also been shown to play a role in Caenorhabditis elegans killing. Screening of large numbers of microbial mutants for attenuation in a mammalian model would require thousands of mice, rats or rabbits. In contrast, the Caenorhabditis elegans model allows rapid identification of mutants in microbial genes associated with pathogenesis and then these phenotypes can be confirmed in a relevant mammalian model.
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[
2015]
This chapter focuses on the nematode (roundworm) Caenorhabditis elegans as an example of the phylum Nematoda. C. elegans provides a powerful genetic system for studying glycans during embryological development and in primitive organ systems.
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Curr Biol,
1999]
RNA -mediated gene interference (RNAi), a rapid, convenient tool for inhibiting gene function in Caenorhabditis elegans, has recently been shown to work in other organisms.