Animals exhibit variations in the burst pharyngeal pumping response to light, during which the pharyngeal pumping rate slightly increases during the5-10 seconds after light exposure onset, compared to controls.
Animals exhibit variations in the recovery pharyngeal pumping response to light, during which the pharyngeal pumping rate slowly increases during the 0-10 seconds afterremoval of light exposure, compared to controls.
Animals exhibit an enhanced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a greater extent than in controls.
Animals exhibit a reduced burst pharyngeal pumping response to light, such that during the5-10 seconds after light exposure onset the pharyngeal pumping rate increases to a lesser extent than in controls.
Animals exhibit a reduced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increasesto a lesser extent than in controls.
Animals die during embryonic development. In C. elegans, often assayed as refractile eggs that fail to hatch; when applied to large-scale RNAi screens in C. elegans, more than 10% of embryos die.
Animals exhibit an enhanced recovery pharyngeal pumping response to light, such that during the 0-10 seconds after removal of light exposure the pharyngeal pumping rate increases to a greater extent than in controls.
Premature lethality during the adult stage. When applied to large-scale RNAi screens in C. elegans, this phenotype is present in at least 10% of analyzed worms, or at least 30% in the case of rrf-3 perturbed background.
Animals do not respond with sleeping behavior induced through the EGF pathway. The EGF-induced sleep pathway is thought to represent a distinct molecular pathway from developmentally linked sleep. The EGF-induced sleep state occurs in two contexts: by overexpressing the EGF ortholog (LIN-3C), or by EGF signaling after stress (such as temperature elevation) in wildtype animals.