(A) Fluorescent signals observed under low magnification in an adult transgenic worm expressing a full-length TDP-1::GFP fusion under control of the endogenous
tdp-1 promoter. The head (h) and tail (t) of the animal are indicated. GFP is observed in many tissues and appears to be primarily nuclear. (B) High magnification image of the head of a TDP-1::GFP transgenic revealing expression in head neurons (n) as well as the intestine (i). (C) High magnification image of the tail region of a TDP-1::GFP transgenic revealing expression in tail neurons (n) as well as muscle cells (m). (D) High magnification image revealing the expression of TDP-1::GFP in intestinal (i) cells.