mid-L4 miRNA expression change

miRNA expression change N2 mid-L4 larvae (Waterston project, Slack subgroup)

Details

small RNAs (<200bp) were isolated from mid-L4 larvae, and sequenced using Illumina technology. We show changes in expression levels for each miRNA feature.

Series Description

We report a significant number of miRNAs and other non-coding small RNAs show dramatic changes in expression during aging in C. elegans. RNAs were prepared from four diffrent timepoints during adulthood of C. elegans hermaphrodites, Day 0, 5, 8 and 12 post-L4 molt, and used for making cDNA libraries for small RNAs. Each library was sequenced using recent advances in high-throughput sequencing technology, Solexa. This study should lead to a better understanding of the aging process and age-related diseases.

Protocols

  1. Other Protocols: small RNA annotation

Sample Details

  1. Animals/Lines: Caenorhabditis elegans
  2. External Links: GSM336059

Related modENCODE submissions:


Release Date: 2010-02-13