WormBase Tree Display for Expr_pattern: Expr9917
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| Expr9917 | Expression_of | Gene | WBGene00001864 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00001864 | |||
| Expression_data | Anatomy_term | WBbt:0005175 | Certain | |
| GO_term | GO:0000793 | |||
| Subcellular_localization | HIM-5 protein is found associated with chromosomes from the mitotic region of the germline until late pachytene. HIM-5 can be seen at low levels in the mitotic zone, accumulates in the transition zone and early pachytene, and decreases mildly upon entry into pachytene and more dramatically in late pachytene. No staining is observed outside of the gonad. In the germlines of wild type hermaphrodites, HIM-5 preferentially localizes to most meiotic chromosomes but is clearly excluded from one pair. To determine if HIM-5 is also under-represented on the X, hermaphrodite germlines were co-stained with anti- XND-1 and anti-HIM-5 antibodies. XND-1 and HIM-5 co-localize to the same subset of chromosomes, indicating that HIM-5 is also enriched on autosomes. | |||
| Type | Antibody | The HIM-5 antibody was made by Strategic Diagnostics Inc. (Newark, DE) as part of the modENCODE project using the ~100 C- terminal amino acids of the protein. | ||
| Picture | WBPicture0000011054 | |||
| Reference | WBPaper00040572 |
