WormBase Tree Display for Gene: WBGene00000229
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| WBGene00000229 | SMap | S_parent | Sequence | C34E10 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 1 | |||||||
| Name | CGC_name | atp-2 | Person_evidence | WBPerson364 | |||||
| Sequence_name | C34E10.6 | ||||||||
| Molecular_name | C34E10.6 | ||||||||
| C34E10.6.1 | |||||||||
| CE29950 | |||||||||
| C34E10.6.2 | |||||||||
| Other_name | CELE_C34E10.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | atp-2 | ||||||||
| DB_info | Database (12) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:20 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | atp | ||||||||
| Allele (29) | |||||||||
| Strain | WBStrain00006141 | ||||||||
| WBStrain00001205 | |||||||||
| WBStrain00024104 | |||||||||
| WBStrain00024105 | |||||||||
| WBStrain00037206 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (53) | |||||||||
| Contained_in_operon | CEOP3268 | ||||||||
| Ortholog (35) | |||||||||
| Paralog | WBGene00004959 | Caenorhabditis elegans | From_analysis | WormBase-Compara | |||||
| WBGene00006921 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00010419 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00012040 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| WBGene00013025 | Caenorhabditis elegans | From_analysis | WormBase-Compara | ||||||
| Structured_description | Concise_description | atp-2 encodes the beta subunit of the soluble, catalytic F1 portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); atp-2 activity is required for embryonic and larval development past the L3 stage, as well as for normal mobility, pharyngeal pumping, defecation, growth rate, and larval lifespan; in males, atp-2 activity is also required cell autonomously in male-specific sensory neurons for response to hermaphrodite contact, the first step in a series of stereotypical male mating behaviors; in vitro, the N-terminus of ATP-2 interacts directly with the conserved PLAT domains of human polycystin (PC)-1 and C. elegans LOV-1, which is expressed exclusively in adult male sensory neurons and is also required for the response to hermaphrodite contact; atp-2 is widely expressed throughout development in both sexes; ATP-2 localizes to mitochondria and to cilia of male-specific neurons; in the male-specific CEM neurons ATP-2 colocalizes with PKD-2, the C. elegans homolog of human polycystin (PC)-2. | Paper_evidence | WBPaper00004403 | |||||
| WBPaper00004813 | |||||||||
| WBPaper00024944 | |||||||||
| Curator_confirmed | WBPerson48 | ||||||||
| WBPerson1843 | |||||||||
| Date_last_updated | 16 Jan 2007 00:00:00 | ||||||||
| Automated_description | Enables protein domain specific binding activity. Involved in several processes, including determination of adult lifespan; inductive cell migration; and pharyngeal pumping. Located in mitochondrion and non-motile cilium. Expressed in HOB; head; ray neuron type B; and tail. Is an ortholog of human ATP5F1B (ATP synthase F1 subunit beta). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | C34E10.6 | |||||||
| Corresponding_transcript | C34E10.6.1 | ||||||||
| C34E10.6.2 | |||||||||
| Other_sequence (447) | |||||||||
| Associated_feature (19) | |||||||||
| Experimental_info (11) | |||||||||
| Map_info | Map | III | Position | -1.91727 | Error | 0.020951 | |||
| Positive | Positive_clone | C34E10 | Inferred_automatically | From CDS info | |||||
| From sequence, transcript, pseudogene data | |||||||||
| Mapping_data | Multi_point | 4167 | |||||||
| 4513 | |||||||||
| Pseudo_map_position | |||||||||
| Reference (48) | |||||||||
| Remark | Sequence connection from [Tsang LW, Lemire BD] | ||||||||
| Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | ||||||||
| Method | Gene |
