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WormBase Tree Display for Gene: WBGene00001683

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Name Class

WBGene00001683SMapS_parentSequenceT09F3
IdentityVersion1
NameCGC_namegpd-1Person_evidenceWBPerson1051
Sequence_nameT09F3.3
Molecular_nameT09F3.3
T09F3.3.1
CE02343
Other_nameCELE_T09F3.3Accession_evidenceNDBBX284602
Public_namegpd-1
DB_infoDatabase (11)
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:25WBPerson1971EventImportedInitial conversion from geneace
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classgpd
Allele (23)
Legacy_information[C.elegansII] NMK. Encodes glyceraldehyde-3-phosphate-dehydrogenase, minor isozyme (GAPDHase-1), ubiquitous, predominant expression in embryo; sequence closest to gpd-4. [Barrios et al. 1989; HH]
RNASeq_FPKM (74)
GO_annotation (14)
Contained_in_operonCEOP2484
Ortholog (60)
ParalogWBGene00001686Caenorhabditis elegansFrom_analysisTreeFam
Inparanoid_8
Panther
WormBase-Compara
WBGene00001685Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
WBGene00001684Caenorhabditis elegansFrom_analysisInparanoid_8
Panther
WormBase-Compara
Structured_descriptionConcise_descriptiongpd-1 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-1 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; GPD-1 is required for embryogenesis, normal body morphology, and gonad development; in C. elegans, GPD-1 and GPD-4 constitute the minor GAPDH isoenzymes and are expressed primarily in embryos, in all cell types.Paper_evidenceWBPaper00000730
WBPaper00001143
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Automated_descriptionPredicted to enable glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity. Predicted to be involved in glycolytic process. Predicted to be located in cytosol. Expressed in germ line. Human ortholog(s) of this gene implicated in Alzheimer's disease and lymphangioleiomyomatosis. Is an ortholog of human GAPDH (glyceraldehyde-3-phosphate dehydrogenase).Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS290 version of WormBase
Date_last_updated11 Sep 2023 00:00:00
Disease_infoPotential_modelDOID:10652Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
DOID:3319Homo sapiensInferred_automaticallyInferred by orthology to human genes with DO annotation (HGNC:4141)
Molecular_infoCorresponding_CDST09F3.3
Corresponding_transcriptT09F3.3.1
Other_sequence (202)
Associated_featureWBsf1013017
WBsf222004
Experimental_infoRNAi_resultWBRNAi00018506Inferred_automaticallyRNAi_primary
WBRNAi00052969Inferred_automaticallyRNAi_primary
WBRNAi00008168Inferred_automaticallyRNAi_primary
WBRNAi00008043Inferred_automaticallyRNAi_primary
WBRNAi00114592Inferred_automaticallyRNAi_primary
WBRNAi00046227Inferred_automaticallyRNAi_primary
WBRNAi00014257Inferred_automaticallyRNAi_primary
WBRNAi00115891Inferred_automaticallyRNAi_primary
Expr_patternExpr776
Expr4125
Expr1031003
Expr1156572
Expr2012205
Expr2030441
Drives_constructWBCnstr00036773
Construct_productWBCnstr00036773
Microarray_resultsSMD_T09F3.3
A_12_P101710
GPL19516_CGZ0034430
GPL19516_CGZ0034431
GPL21109_T09F3.3.1
GPL3518_CE02343
GPL8304_CE_WBGene00001683_A
GPL8304_CE_WBGene00001683_B
Expression_cluster (186)
Interaction (162)
Map_infoMapIIPosition2.55928Error0.007034
PositivePositive_cloneHH#7B
T09F3Inferred_automaticallyFrom sequence, transcript, pseudogene data
Pseudo_map_position
Reference (25)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene