WormBase Tree Display for Gene: WBGene00004350
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| WBGene00004350 | SMap | S_parent | Sequence | F56B6 | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 2 | |||||||
| Name | CGC_name | rgs-7 | Person_evidence | WBPerson330 | |||||
| Sequence_name | F56B6.2 | ||||||||
| Molecular_name (27) | |||||||||
| Other_name | CELE_F56B6.2 | Accession_evidence | NDB | BX284606 | |||||
| Public_name | rgs-7 | ||||||||
| DB_info | Database | AceView | gene | XE175 | |||||
| WormQTL | gene | WBGene00004350 | |||||||
| WormFlux | gene | WBGene00004350 | |||||||
| NDB | locus_tag | CELE_F56B6.2 | |||||||
| Panther | gene | CAEEL|WormBase=WBGene00004350|UniProtKB=Q8WQC0 | |||||||
| family | PTHR10845 | ||||||||
| NCBI | gene | 180645 | |||||||
| RefSeq | protein | NM_001129682.5 | |||||||
| NM_001373262.3 | |||||||||
| NM_001373261.4 | |||||||||
| NM_001374994.1 | |||||||||
| NM_001029543.5 | |||||||||
| NM_001129681.4 | |||||||||
| NM_001373260.4 | |||||||||
| NM_001029544.6 | |||||||||
| NM_076209.7 | |||||||||
| SwissProt | UniProtAcc | Q8WQC0 | |||||||
| TrEMBL | UniProtAcc | A0A4V0IJG9 | |||||||
| Q1W0R0 | |||||||||
| H2KYQ7 | |||||||||
| A0A4V0IKM4 | |||||||||
| A0A4V0ILX5 | |||||||||
| H2KYQ8 | |||||||||
| UniProt_GCRP | UniProtAcc | Q8WQC0 | |||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:35 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 03 Dec 2004 16:13:27 | WBPerson2970 | Event | Acquires_merge | WBGene00018936 | ||||
| Acquires_merge | WBGene00018936 | ||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | rgs | ||||||||
| Allele (194) | |||||||||
| Strain | WBStrain00026370 | ||||||||
| WBStrain00026372 | |||||||||
| WBStrain00032622 | |||||||||
| WBStrain00034758 | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation | 00021823 | ||||||||
| 00021824 | |||||||||
| 00021825 | |||||||||
| 00085200 | |||||||||
| 00085201 | |||||||||
| Ortholog (38) | |||||||||
| Paralog (12) | |||||||||
| Structured_description | Concise_description | rgs-7 encodes three isoforms of an atypical regulator of G protein signaling (RGS) protein that contains both a C2 and an RGS domain, and that binds EGL-30 via both domains, similar in organization to mammalian PDZ-RGS3; the RGS domain has GTPase activator protein (GAP) activity in vitro on mammalian G[alphai]3; RGS-7 thus may stably bind EGL-30 at all stages of EGL-30's GTPase cycle, might organize EGL-30 into a stable multiprotein signalling complex (with GTP[gamma]S), and might persistently inhibit EGL-30 when triggered by calcium or phospholipids; rgs-7 has no obvious function in mass RNAi assays | Paper_evidence | WBPaper00005654 | |||||
| WBPaper00005958 | |||||||||
| WBPaper00013066 | |||||||||
| Curator_confirmed | WBPerson567 | ||||||||
| Date_last_updated | 18 Jun 2007 00:00:00 | ||||||||
| Automated_description | Enables GTPase activator activity. Predicted to be involved in negative regulation of signal transduction. Located in cell cortex. Is an ortholog of several human genes including RGS1 (regulator of G protein signaling 1); RGS13 (regulator of G protein signaling 13); and RGS4 (regulator of G protein signaling 4). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Molecular_info | Corresponding_CDS | F56B6.2a | |||||||
| F56B6.2b | |||||||||
| F56B6.2c | |||||||||
| F56B6.2e | |||||||||
| F56B6.2f | |||||||||
| F56B6.2g | |||||||||
| F56B6.2h | |||||||||
| F56B6.2i | |||||||||
| F56B6.2j | |||||||||
| Corresponding_CDS_history | F56B6.2d:wp271 | ||||||||
| Corresponding_transcript | F56B6.2a.1 | ||||||||
| F56B6.2b.1 | |||||||||
| F56B6.2c.1 | |||||||||
| F56B6.2e.1 | |||||||||
| F56B6.2f.1 | |||||||||
| F56B6.2g.1 | |||||||||
| F56B6.2h.1 | |||||||||
| F56B6.2i.1 | |||||||||
| F56B6.2j.1 | |||||||||
| Other_sequence (21) | |||||||||
| Associated_feature (27) | |||||||||
| Experimental_info | RNAi_result | WBRNAi00048645 | Inferred_automatically | RNAi_primary | |||||
| WBRNAi00048644 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00032932 | Inferred_automatically | RNAi_primary | |||||||
| WBRNAi00015785 | Inferred_automatically | RNAi_primary | |||||||
| Expr_pattern | Expr3108 | ||||||||
| Expr1025711 | |||||||||
| Expr1032168 | |||||||||
| Expr1152407 | |||||||||
| Expr1200208 | |||||||||
| Expr2015330 | |||||||||
| Expr2033564 | |||||||||
| Drives_construct | WBCnstr00011142 | ||||||||
| WBCnstr00035547 | |||||||||
| Construct_product | WBCnstr00011142 | ||||||||
| WBCnstr00035547 | |||||||||
| Microarray_results (53) | |||||||||
| Expression_cluster (147) | |||||||||
| Interaction (11) | |||||||||
| WBProcess | WBbiopr:00000017 | ||||||||
| Map_info | Map | X | Position | -10.1117 | Error | 0.033929 | |||
| Positive | Positive_clone | F56B6 | Inferred_automatically | From sequence, transcript, pseudogene data | |||||
| Mapping_data | Multi_point | 5042 | |||||||
| Pseudo_map_position | |||||||||
| Reference | WBPaper00004281 | ||||||||
| WBPaper00010184 | |||||||||
| WBPaper00010619 | |||||||||
| WBPaper00010738 | |||||||||
| WBPaper00019732 | |||||||||
| WBPaper00024480 | |||||||||
| WBPaper00024864 | |||||||||
| WBPaper00025439 | |||||||||
| WBPaper00027230 | |||||||||
| WBPaper00027672 | |||||||||
| WBPaper00029025 | |||||||||
| WBPaper00032337 | |||||||||
| WBPaper00033032 | |||||||||
| WBPaper00038491 | |||||||||
| WBPaper00051799 | |||||||||
| WBPaper00055090 | |||||||||
| WBPaper00055830 | |||||||||
| Remark | Map position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC. | CGC_data_submission | |||||||
| Method | Gene |
