WormBase Tree Display for Gene: WBGene00006811
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| WBGene00006811 | SMap | S_parent | Sequence | CHROMOSOME_III | |||||
|---|---|---|---|---|---|---|---|---|---|
| Identity | Version | 4 | |||||||
| Name | CGC_name | unc-79 | Person_evidence | WBPerson261 | |||||
| Sequence_name | E03A3.6 | ||||||||
| Molecular_name | E03A3.6a | ||||||||
| E03A3.6a.1 | |||||||||
| CE43495 | |||||||||
| E03A3.6b | |||||||||
| CE30720 | |||||||||
| E03A3.6b.1 | |||||||||
| E03A3.6b.2 | |||||||||
| E03A3.6b.3 | |||||||||
| Other_name | CELE_E03A3.6 | Accession_evidence | NDB | BX284603 | |||||
| Public_name | unc-79 | ||||||||
| DB_info | Database (11) | ||||||||
| Species | Caenorhabditis elegans | ||||||||
| History | Version_change | 1 | 07 Apr 2004 11:29:43 | WBPerson1971 | Event | Imported | Initial conversion from geneace | ||
| 2 | 16 Jul 2007 17:47:14 | WBPerson1983 | Event | Acquires_merge | WBGene00008466 | ||||
| 3 | 16 Jul 2007 17:49:52 | WBPerson1983 | Event | Acquires_merge | WBGene00007272 | ||||
| 4 | 19 Jul 2007 11:54:11 | WBPerson1983 | Event | Acquires_merge | WBGene00008467 | ||||
| Acquires_merge | WBGene00008466 | ||||||||
| WBGene00007272 | |||||||||
| WBGene00008467 | |||||||||
| Status | Live | ||||||||
| Gene_info | Biotype | SO:0001217 | |||||||
| Gene_class | unc | ||||||||
| Reference_allele | WBVar00143719 | ||||||||
| Allele (224) | |||||||||
| Legacy_information | e1068 : irregular movement somewhat sluggish. ES2 ME3. NA4 (e1031 etc.). | ||||||||
| See also e1030, e1031, e1068, e1291, e1510 | |||||||||
| [C.elegansII] e1068 : irregular movement, somewhat sluggish ("fainter"); hypersensitive to volatile anaesthetics.ES2 ME3. OA>5: e1031, e1291, e1510, ec1 etc. [Sedensky and Meneely 1987; Morgan et al. 1991; CW] | |||||||||
| Strain (12) | |||||||||
| RNASeq_FPKM (74) | |||||||||
| GO_annotation (11) | |||||||||
| Ortholog (43) | |||||||||
| Structured_description | Concise_description | unc-79 encodes a novel, conserved protein; unc-79 functions in a pathway with unc-77 and nca-2, which encode alpha-1 subunits of voltage-insensitive cation leak channels, to regulate locomotion and the response to specific volatile anesthetics; unc-79 exerts its effects on these processes, at least in part, by regulating the levels of UNC-77 and NCA-2 proteins; an unc-79::gfp reporter is expressed in the nervous system in ventral nerve cord neurons in L2 and L3 larvae and in one or two head neurons in adults; UNC-79 exhibits a punctate staining pattern in ventral nerve cord and nerve ring processes, and this staining is dependent upon UNC-80, UNC-77, and NCA-2. | Paper_evidence | WBPaper00001281 | |||||
| WBPaper00030757 | |||||||||
| WBPaper00031592 | |||||||||
| Curator_confirmed | WBPerson1843 | ||||||||
| WBPerson324 | |||||||||
| Date_last_updated | 22 Jun 2010 00:00:00 | ||||||||
| Automated_description | Involved in several processes, including response to anesthetic; response to ethanol; and response to toluene. Located in axon. Expressed in head neurons; nerve ring; nervous system; tail neurons; and ventral cord neurons. Used to study alcohol use disorder. Is an ortholog of human UNC79 (unc-79 homolog, NALCN channel complex subunit). | Paper_evidence | WBPaper00065943 | ||||||
| Curator_confirmed | WBPerson324 | ||||||||
| WBPerson37462 | |||||||||
| Inferred_automatically | This description was generated automatically by a script based on data from the WS291 version of WormBase | ||||||||
| Date_last_updated | 29 Nov 2023 00:00:00 | ||||||||
| Disease_info | Experimental_model | DOID:1574 | Homo sapiens | Paper_evidence | WBPaper00002358 | ||||
| Curator_confirmed | WBPerson324 | ||||||||
| Date_last_updated | 29 Apr 2019 00:00:00 | ||||||||
| Models_disease_in_annotation | WBDOannot00000654 | ||||||||
| Molecular_info | Corresponding_CDS | E03A3.6a | |||||||
| E03A3.6b | |||||||||
| Corresponding_CDS_history | E03A3.6:wp79 | ||||||||
| E03A3.6:wp179 | |||||||||
| E03A3.6:wp183 | |||||||||
| E03A3.6a:wp200 | |||||||||
| Corresponding_transcript | E03A3.6a.1 | ||||||||
| E03A3.6b.1 | |||||||||
| E03A3.6b.2 | |||||||||
| E03A3.6b.3 | |||||||||
| Other_sequence (50) | |||||||||
| Associated_feature (23) | |||||||||
| Experimental_info | RNAi_result (26) | ||||||||
| Expr_pattern | Expr8062 | ||||||||
| Expr8326 | |||||||||
| Expr16167 | |||||||||
| Expr1027571 | |||||||||
| Expr1032877 | |||||||||
| Expr1147615 | |||||||||
| Expr2017908 | |||||||||
| Expr2036044 | |||||||||
| Drives_construct | WBCnstr00013262 | ||||||||
| WBCnstr00017149 | |||||||||
| WBCnstr00042791 | |||||||||
| Construct_product | WBCnstr00017149 | ||||||||
| Antibody | WBAntibody00001385 | ||||||||
| WBAntibody00002202 | |||||||||
| Microarray_results (50) | |||||||||
| Expression_cluster (204) | |||||||||
| Interaction (66) | |||||||||
| Map_info | Map | III | Position | -3.89038 | Error | 0.022171 | |||
| Well_ordered | |||||||||
| Positive | Inside_rearr | nDf10 | |||||||
| nDf11 | |||||||||
| nDf14 | |||||||||
| Positive_clone | E03A3 | Inferred_automatically | From sequence, transcript, pseudogene data | ||||||
| Mapping_data | 2_point | 60 | |||||||
| 2714 | |||||||||
| 7066 | |||||||||
| Multi_point (30) | |||||||||
| Pos_neg_data (14) | |||||||||
| Reference (74) | |||||||||
| Method | Gene |
