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WormBase Tree Display for Gene: WBGene00006825

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Name Class

WBGene00006825SMapS_parentSequenceF13C5
IdentityVersion2
NameCGC_nameunc-96Paper_evidenceWBPaper00027703
Person_evidenceWBPerson261
Sequence_nameF13C5.6
Molecular_nameF13C5.6a
F13C5.6a.1
CE27424
F13C5.6b
CE29760
F13C5.6b.1
Other_namegei-10Person_evidenceWBPerson1796
CELE_F13C5.6Accession_evidenceNDBBX284606
Public_nameunc-96
DB_infoDatabaseAceViewgeneXB230
WormQTLgeneWBGene00006825
WormFluxgeneWBGene00006825
NDBlocus_tagCELE_F13C5.6
NCBIgene180413
RefSeqproteinNM_171939.5
NM_171612.8
TREEFAMTREEFAM_IDTF316199
TrEMBLUniProtAccO76566
H2KZR3
UniProt_GCRPUniProtAccH2KZR3
SpeciesCaenorhabditis elegans
HistoryVersion_change107 Apr 2004 11:29:43WBPerson1971EventImportedInitial conversion from geneace
202 Feb 2007 10:15:15WBPerson2970EventAcquires_mergeWBGene00001567
Name_changeOther_namegei-10
Acquires_mergeWBGene00001567
StatusLive
Gene_infoBiotypeSO:0001217
Gene_classunc
Reference_alleleWBVar00248853
Allele (153)
Legacy_informationsu151 : very slightly slow slightly Egl moves well; abnormal muscle birefringence and ultrastruture collections of thin filaments near ends of cells. ES1 ME3. NA1.
[C.elegansII] su151 : very slightly slow, slightly Egl, moves well; abnormal muscle birefringence and ultrastructure, collections of thin filaments near ends of cells. ES1 ME3. NA1. [Zengel and Epstein 1980; HE]
StrainWBStrain00007703
WBStrain00008393
RNASeq_FPKM (74)
GO_annotation (14)
Ortholog (27)
Structured_descriptionConcise_descriptionunc-96 encodes a novel protein with no recognizable domains; unc-96 was identified in screens for mutations that disrupt body wall muscle cell structure and is required for muscle thick filament assembly, maintenance of muscle organization in response to muscle contraction, and normal locomotion; mutations in unc-96 interact genetically with mutations in unc-54, unc-98, unc-15, and unc-105, which encode a muscle-specific myosin heavy chain, zinc finger protein, paramyosin, and degenerin, respectively; in addition, UNC-96 physically interacts with UNC-98 and UNC-15, the latter of which is required for proper UNC-96 localization in body wall muscle; UNC-96 is found in body wall, pharyngeal, and anal depressor muscles; UNC-96 copurifies with thick filaments; antibody staining indicates that UNC-96 localizes to M-lines, while GFP tagging indicates that UNC-96 localizes to both M-lines and dense bodies.Paper_evidenceWBPaper00000488
WBPaper00005938
WBPaper00027703
Curator_confirmedWBPerson1843
Date_last_updated31 Jul 2007 00:00:00
Automated_descriptionEnables myosin binding activity. Involved in locomotion; regulation of cytoskeleton organization; and striated muscle myosin thick filament assembly. Located in M band and striated muscle myosin thick filament. Expressed in anal depressor muscle; body wall musculature; and pharyngeal muscle cell.Paper_evidenceWBPaper00065943
Curator_confirmedWBPerson324
WBPerson37462
Inferred_automaticallyThis description was generated automatically by a script based on data from the WS291 version of WormBase
Date_last_updated29 Nov 2023 00:00:00
Molecular_infoCorresponding_CDSF13C5.6a
F13C5.6b
Corresponding_transcriptF13C5.6a.1
F13C5.6b.1
Other_sequence (22)
Associated_feature (12)
Experimental_infoRNAi_result (15)
Expr_patternExpr7859
Expr7860
Expr7861
Expr1021808
Expr1032889
Expr1148443
Expr2017922
Expr2036058
Drives_constructWBCnstr00012957
WBCnstr00034134
Construct_productWBCnstr00012957
WBCnstr00034134
AntibodyWBAntibody00001112
Microarray_results (24)
Expression_cluster (146)
Interaction (31)
Map_infoMapXPosition-19.557Error0.643684
PositivePositive_cloneF13C5Inferred_automaticallyFrom sequence, transcript, pseudogene data
Mapping_data2_point395
Multi_point313
4495
5271
5713
Reference (22)
MethodGene