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WormBase Tree Display for RNAi: WBRNAi00110535

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Name Class

WBRNAi00110535HomolHomol_homolDY3:RNAi
Sequence_infoPCR_productsjj_DY3.3
ExperimentGenotyperrf-3(pk1426); hlh-2(bx115) unc-13(e51); mgIs18 [ttx-3prom::gfp]
InhibitsPredicted_geneDY3.3Inferred_automaticallyRNAi_primary
GeneWBGene00001960Inferred_automaticallyRNAi_primary
TranscriptDY3.3.1Inferred_automaticallyRNAi_primary
SpeciesCaenorhabditis elegans
ReferenceWBPaper00039859
PhenotypeWBPhenotype:0001224RemarkAuthors found that RNAi against hlh-16 affected the outgrowth of the axons of both AIY interneurons into the nerve ring such that they stop prematurely. AIYL was significantly more affected than AIYR.
Remarkpk1426 globally sensitizing animals to the effects of RNAi and bx115 (a mutation in the bHLH cofactor hlh-2) sensitizing animals for the loss of function of other bHLH factors. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation. No methods of RNAi introduction to organism given.
MethodRNAi