WormBase Tree Display for Disease_model_annotation: WBDOannot00000745
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| WBDOannot00000745 | Disease_term | DOID:11723 | |
|---|---|---|---|
| Disease_of_species | Homo sapiens | ||
| Modeled_by | Strain | WBStrain00024340 | |
| Asserted_gene | WBGene00001131 | ||
| WBGene00001948 | |||
| Association_type | is_model_of | ||
| Evidence_code | GO_code | IMP | |
| ECO_term | ECO:0007013 | ||
| Modifier_info | Modifier_molecule | WBMol:00001788 | |
| Modifier_association_type | condition_ameliorated_by | ||
| Genetic_sex | hermaphrodite | ||
| Paper_evidence | WBPaper00056839 | ||
| Disease_model_description | Treatment of a Duchenne muscular dystrophy (DMD) worm model LS587 (dys-1(cx18) I; hlh-1(cc561) II) with actinonin, a matrix metalloproteinase (MMP) inhibitor, resulted in a significant reduction in muscle damage, through prevention of extracellular matrix and collagen degradation. | ||
| Curator_confirmed | WBPerson324 | ||
| Date_last_updated | 17 Mar 2020 00:00:00 |
