WormBase Tree Display for Expr_pattern: Expr1040
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Expr1040 | Expression_of | Gene | WBGene00003001 | |
---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00003001 | |||
Expression_data | Life_stage | WBls:0000018 | ||
Anatomy_term | WBbt:0005792 | Certain | ||
Type | Antibody | Affinity-purified antiserum against the LIN-12 protein. | ||
Pattern | LIN-12 expression is first detected at very low, but above background, levels in each of the cells in the E4 intestinal primordium. By the E8 stage, LIN-12 appears most abundant in cells in the right half of the primordium, and is present at lower or undetectable levels in cells in the left half. The left-right asymmetry in LIN-12 expression persists to the E16 stage, when dynamic changes in LIN-12 expression occur along the anterior-posterior axis of the primordium. At the E16 stage, LIN-12 is prominent in punctate structures near the midline of the primordium; these structures resemble in shape, position and timing of appearance the 'apical vesicles' described in an ultrastructural study of the primordium. | |||
Picture | WBPicture0000008061 | |||
Remark | Authors only analyzed the expression pattern of LIN-12 before and during intestinal twist. The patterns describe are not observed in embryos from lin-12(n941) hermaphrodites or from lin-12(RNAi) hermaphrodites, and are thus specific for LIN-12. | |||
Reference | WBPaper00004315 | |||
Antibody_info | WBAntibody00000303 |