WormBase Tree Display for Expr_pattern: Expr1084
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Expr1084 | Expression_of | Gene | WBGene00003002 | ||
---|---|---|---|---|---|
Reflects_endogenous_expression_of | WBGene00003002 | ||||
Expression_data | Life_stage | WBls:0000002 | |||
Anatomy_term | WBbt:0005734 | Certain | |||
WBbt:0005753 | Certain | ||||
WBbt:0008112 | Uncertain | ||||
Remark | Occasional expression. | ||||
WBbt:0008117 | Uncertain | ||||
Remark | Occasional expression. | ||||
WBbt:0008121 | Uncertain | ||||
Remark | Occasional expression. | ||||
WBbt:0008125 | Uncertain | ||||
Remark | Occasional expression. | ||||
WBbt:0008129 | Uncertain | ||||
Remark | Occasional expression. | ||||
WBbt:0008133 | Uncertain | ||||
Remark | Occasional expression. | ||||
GO_term | GO:0005634 | ||||
Subcellular_localization | The LIN-13::GFP hybrid proteins localize to the nucleus. In the nucleus, there are also discrete bodies or speckles of fluorescence; other nuclear proteins have been found to localize in such patterns, but in most cases the functional significance of these structures is not clear. Nuclear accumulation observed in other cell types (not characterized in detail, but the expression pattern of LIN-13::GFP seems roughly equivalent to that of lin-13::lacZ). | ||||
Type | Reporter_gene | ||||
Pattern | Significant GFP fluorescence seen in embryos of living animals (not determined the cell types). In living larvae, however, expression is very low, and in particular no expression was detected during the L3 stage. Hermaphrodites fixed and stained with antibodies to GFP showed consistent LIN-13::GFP accumulation in the nuclei of hyp7 and in seam cells throughout development, including the L3 stage. No reliable expression of LIN-13::GFP observed in the VPCs, although occasionally detected GFP in one or two VPCs in fixed and antibody-stained hermaphrodites. | ||||
Picture | WBPicture0000011722 | ||||
Remark | Transgenes expressing either of these LIN-13::GFP hybrid proteins fully rescue the Muv and sterility defects of lin-13(n387) and appear to have identical expression patterns. | ||||
Reference | WBPaper00004202 | ||||
Transgene | WBTransgene00000049 | ||||
WBTransgene00000050 |