WormBase Tree Display for Expr_pattern: Expr11228
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| Expr11228 | Expression_of | Gene | WBGene00194892 | |
|---|---|---|---|---|
| WBGene00008580 | ||||
| Reflects_endogenous_expression_of | WBGene00008580 | |||
| WBGene00194892 | ||||
| Expression_data | Anatomy_term | WBbt:0005175 | Certain | |
| GO_term | GO:0005634 | |||
| GO:0000785 | ||||
| Subcellular_localization | Nuclear localization of DSB-1 and DSB-2 is detected in the same region of the gonad, and their staining patterns on chromatin have a similar appearance. However, the relative intensity patterns of the two proteins differ during meiotic progression. Within the gonad, DSB-1 signal is detected on nuclei slightly before DSB-2 and has a stronger intensity early on, which then declines as nuclei progress through pachytene (except for the outlier nuclei); DSB-2 signal is weaker early on and peaks in intensity later than DSB-1 before eventually declining. Both proteins disappear from nuclei at the same time, and both localize to the same outlier nuclei. Within each nucleus, the intensity patterns on chromatin are also different, such that the DSB-1 and DSB-2 signals partially overlap but do not match each other. | |||
| Type | Antibody | |||
| Picture | WBPicture0000013312 | |||
| Reference | WBPaper00044072 | |||
| Antibody_info | WBAntibody00002458 |
