WormBase Tree Display for Expr_pattern: Expr12013
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| Expr12013 | Expression_of | Gene | WBGene00019126 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00019126 | |||
| Expression_data | Anatomy_term | WBbt:0006749 | Certain | |
| GO_term | GO:0030672 | |||
| Subcellular_localization | SAM-4 preferentially accumulates in the synaptic varicosities of PLMs and small quantities of SAM-4 accumulate as puncta in the neurites. Further examination demonstrated that these SAM-4 particles colocalize well with the RAB-3 labeled SV particles. By cell fractionation it was observed that, like the SV protein synaptobrevin SNB-1, SAM-4 was present in the SV membrane containing pellet but was absent from the cytosolic fraction, indicating that SAM-4 is likely associated with SVs. | |||
| Type | Reporter_gene | |||
| Pattern | Immunohistochemical analysis of the transgene revealed that SAM-4 is localized primarily to the nerve ring region of the head, indicating that sam-4 is broadly expressed in the nervous system. | |||
| Picture | WBPicture0000013805 | |||
| Reference | WBPaper00045884 | |||
| Transgene | WBTransgene00020272 | |||
| WBTransgene00020273 |
