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WormBase Tree Display for Expr_pattern: Expr1329

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Name Class

Expr1329Expression_ofGeneWBGene00006778
Reflects_endogenous_expression_ofWBGene00006778
Expression_dataLife_stageWBls:0000022
WBls:0000015
WBls:0000014
WBls:0000021
Anatomy_termWBbt:0003844Certain
WBbt:0003845Certain
WBbt:0003846Certain
WBbt:0003847Certain
WBbt:0003848Certain
WBbt:0003849Certain
WBbt:0003863Certain
WBbt:0003864Certain
WBbt:0003865Certain
WBbt:0003866Certain
WBbt:0003869Certain
WBbt:0003870Certain
WBbt:0003889Certain
WBbt:0003890Certain
WBbt:0003905Certain
WBbt:0003965Certain
WBbt:0003967Certain
WBbt:0004070Certain
WBbt:0004587Certain
WBbt:0004647Certain
WBbt:0004973Certain
WBbt:0004974Certain
WBbt:0004975Certain
WBbt:0004976Certain
WBbt:0004977Certain
WBbt:0004978Certain
WBbt:0004979Certain
WBbt:0004981Certain
WBbt:0005001Certain
WBbt:0005003Certain
WBbt:0005005Certain
WBbt:0005007Certain
WBbt:0005033Certain
WBbt:0005037Certain
WBbt:0005041Certain
WBbt:0005043Certain
WBbt:0005270Certain
WBbt:0005300Certain
WBbt:0005733Certain
WBbt:0006751Certain
TypeAntibodyPolyclonal mice or rabbit antibody against UNC-42 recombinant protein.
Reporter_gene
PatternUNC-42 expression was detected with a mouse antiserum in several cells as early as 260 minutes of embryogenesis and in neurons at high levels in the head by comma stage, the time when these neurons extend axons and establish connections. Expression in head neurons continues into adulthood. UNC-42 was strongly expressed in at least 20 pairs of neurons of the head, including the AVA, AVD and AVE interneurons, ASH sensory neurons, and RMD and SMB motor neurons. Other neurons that express high levels of UNC-42 include the AIN, AVH, AVJ, AVK, RIV, SAA and SIB interneurons. The same expression pattern in the head was detected in animals that carry a transgene that encodes an UNC-42 protein tagged at its C terminus with GFP(gmEx186). Antiserum to UNC-42 and the gmEx104 GFP reporter gene revealed low levels of unc-42 expression in hypodermis and additional neurons in the head. Transient expression of UNC-42 protein was also detected in the DD motor neurons at hatching and at low levels in postembryonic ventral cord motor neurons derived from P11. UNC-42 protein was not detected in descendants of P2-P10 or P12. In the tail, unc-42-gfp (gmEx104) is strongly expressed in PVT.
PictureWBPicture0000008017
ReferenceWBPaper00003555
TransgeneWBTransgene00027466
Antibody_infoWBAntibody00000226
WBAntibody00000227