WormBase Tree Display for Expr_pattern: Expr13622
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| Expr13622 | Expression_of | Gene | WBGene00018949 | |
|---|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00018949 | |||
| Expression_data | Anatomy_term | WBbt:0005772 | Certain | |
| Type | Reporter_gene | |||
| Pattern | ACBP-4::GFP is found to be specifically localized to granular structures in the intestine. These granules are likely to be fat storage granules, as ACBP- 4::GFP expression could not be observed upon RNAi (RNA interference) knockdown of sbp-1, the C. elegans homologue of the mammalian lipogenic transcription factor SREBP-1c. Furthermore, under the light microscope, the ACBP-4::GFP-labelled granules have the smooth appearance of fat storage granules and not the more-obviously structured appearance of lysosomes. However, we cannot completely rule out the possibility that ACBP-4::GFP is also associated with lysosomes. | |||
| Reference | WBPaper00038378 | |||
| Transgene | WBTransgene00032157 |
