WormBase Tree Display for Expr_pattern: Expr13795
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| Expr13795 | Expression_of | Gene | WBGene00013917 |
|---|---|---|---|
| Reflects_endogenous_expression_of | WBGene00013917 | ||
| Expression_data | GO_term | GO:0005634 | |
| GO:0005737 | |||
| Subcellular_localization | CDK-11.2 protein levels vary throughout the germ line. CDK-11.2 was found in nuclei and cytoplasm; both nuclear and cytoplasmic levels are relatively low in the mitotic region, peak in late pachytene, and then gradually decrease as oocytes mature. CDK-11.2 was also found in the sheath cell nuclei and in the nuclei and cytoplasm of embryos where levels steadily increase as embryos develop. The subcellular distribution of CDK-11.2 appears to be developmental regulated. In the mitotic region, CDK- 11.2 is more concentrated in the cytoplasm than nuclei but as cells enter late pachytene, the protein becomes enriched in nuclei. In oocytes, CDK-11.2 is more evenly distributed between cytoplasm and nuclei, and in embryos the protein is initially evenly distributed between nuclei and cytoplasm but gradually becomes more concentrated in nuclei as embryos develop. This nuclear enrichment is first evident in four- and six-cell stage embryos, and increases during the ensuing cell divisions. | ||
| Type | Reporter_gene | ||
| Reference | WBPaper00054706 | ||
| Transgene | WBTransgene00023832 |
